FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6720, 134 aa 1>>>pF1KB6720 134 - 134 aa - 134 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8877+/-0.000358; mu= 12.9166+/- 0.022 mean_var=53.7980+/-10.861, 0's: 0 Z-trim(112.6): 39 B-trim: 0 in 0/49 Lambda= 0.174860 statistics sampled from 21600 (21639) to 21600 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.254), width: 16 Scan time: 4.100 The best scores are: opt bits E(85289) NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 911 237.5 5e-63 NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 556 147.9 4.6e-36 NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 495 132.6 2.7e-31 NP_113679 (OMIM: 611866) retinol-binding protein 5 ( 135) 460 123.7 9e-29 XP_016875491 (OMIM: 611866) PREDICTED: retinol-bin ( 126) 417 112.8 1.6e-25 NP_001316383 (OMIM: 611866) retinol-binding protei ( 86) 354 96.9 6.9e-21 NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 330 90.9 6.6e-19 NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 301 83.6 1e-16 NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 295 82.1 3e-16 XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 291 81.0 5.8e-16 XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 286 79.8 1.5e-15 NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 286 79.8 1.5e-15 NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 286 79.8 1.5e-15 NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 282 78.8 3e-15 NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 272 76.3 2e-14 NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 268 75.3 3.4e-14 NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 262 73.8 1.1e-13 NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 259 73.0 1.8e-13 NP_001307925 (OMIM: 134651) fatty acid-binding pro ( 144) 257 72.5 2.5e-13 NP_001305971 (OMIM: 602965) fatty acid-binding pro ( 128) 230 65.7 2.5e-11 NP_001305970 (OMIM: 602965) fatty acid-binding pro ( 97) 218 62.6 1.6e-10 NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 190 55.6 2.8e-08 NP_001435 (OMIM: 605168) fatty acid-binding protei ( 135) 184 54.1 8.2e-08 NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 154 46.5 1.5e-05 NP_001436 (OMIM: 600422) gastrotropin isoform 2 [H ( 128) 130 40.4 0.00099 NP_001124430 (OMIM: 600422) gastrotropin isoform 1 ( 177) 130 40.5 0.0013 NP_001035532 (OMIM: 600422) gastrotropin isoform 1 ( 177) 130 40.5 0.0013 >>NP_004155 (OMIM: 180280) retinol-binding protein 2 [Ho (134 aa) initn: 911 init1: 911 opt: 911 Z-score: 1252.5 bits: 237.5 E(85289): 5e-63 Smith-Waterman score: 911; 100.0% identity (100.0% similar) in 134 aa overlap (1-134:1-134) 10 20 30 40 50 60 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL 70 80 90 100 110 120 130 pF1KB6 TCGDQVCRQVFKKK :::::::::::::: NP_004 TCGDQVCRQVFKKK 130 >>NP_443192 (OMIM: 608604) retinoid-binding protein 7 [H (134 aa) initn: 558 init1: 545 opt: 556 Z-score: 768.5 bits: 147.9 E(85289): 4.6e-36 Smith-Waterman score: 556; 59.4% identity (80.5% similar) in 133 aa overlap (1-133:1-133) 10 20 30 40 50 60 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN : : .::: . :..:::::: :: ::::::::: : :::.:.::.: .:.:..:: NP_443 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL : : : :: :::: ...::::. :.:: :..: :.:.:::::.:::: .:::::::.::. NP_443 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM 70 80 90 100 110 120 130 pF1KB6 TCGDQVCRQVFKKK : :::.:.:.. NP_443 FCEGQVCKQTFQRA 130 >>NP_002890 (OMIM: 180260) retinol-binding protein 1 iso (197 aa) initn: 464 init1: 464 opt: 495 Z-score: 682.8 bits: 132.6 E(85289): 2.7e-31 Smith-Waterman score: 495; 55.6% identity (72.9% similar) in 133 aa overlap (1-133:63-195) 10 20 30 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFAT : : .: :.: ::::: :..:::.. : NP_002 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 RKIAVRLTQTKVIDQDGDNFKTKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWE :::: : : : ::::.. .: :::::: .:: :: ::.: ..:.:. . :.:. NP_002 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWD 100 110 120 130 140 150 100 110 120 130 pF1KB6 GDVLVCVQKGEKENRGWKQWIEGDKLYLELTCGDQVCRQVFKKK :: : ::::::::.::: ::::::.:.::. ::.::::: NP_002 GDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ 160 170 180 190 >>NP_113679 (OMIM: 611866) retinol-binding protein 5 iso (135 aa) initn: 437 init1: 421 opt: 460 Z-score: 637.6 bits: 123.7 E(85289): 9e-29 Smith-Waterman score: 460; 51.1% identity (80.5% similar) in 133 aa overlap (1-133:1-133) 10 20 30 40 50 60 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN : . .: ... :..:.: :..::.:..:.::::. : : :...:... ..: ::::: NP_113 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL : :.: :::::.: .:.:.:. ...:::: . :::::::: ::::..:.::. ::::: NP_113 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL 70 80 90 100 110 120 130 pF1KB6 TCGDQVCRQVFKKK : : ::.:::.: NP_113 TARDAVCEQVFRKVR 130 >>XP_016875491 (OMIM: 611866) PREDICTED: retinol-binding (126 aa) initn: 433 init1: 417 opt: 417 Z-score: 579.4 bits: 112.8 E(85289): 1.6e-25 Smith-Waterman score: 417; 56.0% identity (81.7% similar) in 109 aa overlap (25-133:16-124) 10 20 30 40 50 60 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN ::..:.::::. : : :...:... ..: ::::: XP_016 MMNQAQWILKPGTMADISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL : :.: :::::.: .:.:.:. ...:::: . :::::::: ::::..:.::. ::::: XP_016 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL 60 70 80 90 100 110 130 pF1KB6 TCGDQVCRQVFKKK : : ::.:::.: XP_016 TARDAVCEQVFRKVR 120 >>NP_001316383 (OMIM: 611866) retinol-binding protein 5 (86 aa) initn: 363 init1: 347 opt: 354 Z-score: 496.0 bits: 96.9 E(85289): 6.9e-21 Smith-Waterman score: 354; 61.7% identity (82.7% similar) in 81 aa overlap (53-133:4-84) 30 40 50 60 70 80 pF1KB6 ALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRNYDVDFTVGVEFDEYTKSLDNRH .: :::::: :.: :::::.: .:.:.:. NP_001 MTVRTLSTFRNYTVQFDVGVEFEEDLRSVDGRK 10 20 30 90 100 110 120 130 pF1KB6 VKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLELTCGDQVCRQVFKKK ...:::: . :::::::: ::::..:.::. :::::: : ::.:::.: NP_001 CQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR 40 50 60 70 80 >>NP_004093 (OMIM: 134651) fatty acid-binding protein, h (133 aa) initn: 306 init1: 229 opt: 330 Z-score: 460.4 bits: 90.9 E(85289): 6.6e-19 Smith-Waterman score: 330; 42.6% identity (71.3% similar) in 129 aa overlap (7-134:7-132) 10 20 30 40 50 60 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN :::.. ...::. :::.: . ::::..: : .:...:: . :: :::.: NP_004 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGE-KENRGWKQWIEGDKLYLE ...: .:::::: : :.:.::..:: .: :: .:: . .:. .. :.: :: : NP_004 TEISFKLGVEFDETTA--DDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDG-KLILT 70 80 90 100 110 120 130 pF1KB6 LTCGDQVCRQVFKKK :: : :: ....:. NP_004 LTHGTAVCTRTYEKEA 120 130 >>NP_001437 (OMIM: 602965) fatty acid-binding protein, b (132 aa) initn: 310 init1: 210 opt: 301 Z-score: 420.9 bits: 83.6 E(85289): 1e-16 Smith-Waterman score: 301; 38.1% identity (69.0% similar) in 126 aa overlap (8-133:8-131) 10 20 30 40 50 60 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN ::.. ...::. ::::: . ::::... : .:.:.::. .: :::.: NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL ...: .: :::: : :.:. :..:. .:: :: .:: . .. .. . :. :. . : NP_001 TEISFQLGEEFDETTA--DDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTL 70 80 90 100 110 130 pF1KB6 TCGDQVCRQVFKKK : :: : . ..: NP_001 TFGDVVAVRHYEKA 120 130 >>NP_001433 (OMIM: 600434) fatty acid-binding protein, a (132 aa) initn: 294 init1: 211 opt: 295 Z-score: 412.7 bits: 82.1 E(85289): 3e-16 Smith-Waterman score: 295; 39.4% identity (66.1% similar) in 127 aa overlap (7-133:7-131) 10 20 30 40 50 60 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN :::.. :.:::. ::: . . :::::.: . .:. .:: . :. :::.: NP_001 MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL ...: .: :::: : :.:.::. .: .: ::: ::: . .. :. : ::: .: NP_001 TEISFILGQEFDEVTA--DDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVEC 70 80 90 100 110 130 pF1KB6 TCGDQVCRQVFKKK . . .:... NP_001 VMKGVTSTRVYERA 120 130 >>XP_011539309 (OMIM: 134651) PREDICTED: fatty acid-bind (126 aa) initn: 281 init1: 229 opt: 291 Z-score: 407.6 bits: 81.0 E(85289): 5.8e-16 Smith-Waterman score: 291; 41.2% identity (71.1% similar) in 114 aa overlap (7-119:7-118) 10 20 30 40 50 60 pF1KB6 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN :::.. ...::. :::.: . ::::..: : .:...:: . :: :::.: XP_011 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGE-KENRGWKQWIEGDKLYLE ...: .:::::: : :.:.::..:: .: :: .:: . .:. .. :.: . .: XP_011 TEISFKLGVEFDETTA--DDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILME 70 80 90 100 110 120 130 pF1KB6 LTCGDQVCRQVFKKK XP_011 KLQLRNVK 120 134 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:52:35 2016 done: Sat Nov 5 13:52:36 2016 Total Scan time: 4.100 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]