FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6722, 134 aa 1>>>pF1KB6722 134 - 134 aa - 134 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4251+/-0.000265; mu= 12.2355+/- 0.017 mean_var=92.3901+/-18.311, 0's: 0 Z-trim(121.5): 56 B-trim: 0 in 0/54 Lambda= 0.133433 statistics sampled from 38226 (38285) to 38226 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.449), width: 16 Scan time: 4.850 The best scores are: opt bits E(85289) NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 919 185.6 2.1e-47 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 843 171.0 5.7e-43 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 231 53.0 1.2e-07 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 206 48.2 3.5e-06 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 201 47.2 6.5e-06 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 201 47.2 6.9e-06 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 197 46.4 1.1e-05 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 193 45.7 2e-05 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 185 44.2 6.7e-05 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 185 44.2 6.7e-05 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 183 43.8 7.6e-05 NP_001123518 (OMIM: 601960) C-C motif chemokine 20 ( 95) 178 42.8 0.00014 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 175 42.2 0.00021 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 172 41.6 0.00031 NP_004582 (OMIM: 601960) C-C motif chemokine 20 is ( 96) 172 41.6 0.00032 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 171 41.4 0.00036 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 171 41.4 0.00036 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 170 41.2 0.00042 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 170 41.2 0.00042 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 170 41.4 0.00058 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 165 40.3 0.00083 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 161 39.6 0.0016 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 161 39.6 0.0016 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 161 39.6 0.0016 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 154 38.2 0.0035 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 153 37.9 0.0039 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 150 37.4 0.0059 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 150 37.4 0.0059 XP_016882611 (OMIM: 602565) PREDICTED: C-C motif c ( 149) 151 37.8 0.0073 NP_001188288 (OMIM: 602565) C-C motif chemokine 25 ( 149) 151 37.8 0.0073 NP_005615 (OMIM: 602565) C-C motif chemokine 25 is ( 150) 151 37.8 0.0074 XP_016882609 (OMIM: 602565) PREDICTED: C-C motif c ( 150) 151 37.8 0.0074 XP_016882610 (OMIM: 602565) PREDICTED: C-C motif c ( 150) 151 37.8 0.0074 XP_011526479 (OMIM: 602565) PREDICTED: C-C motif c ( 150) 151 37.8 0.0074 XP_016882608 (OMIM: 602565) PREDICTED: C-C motif c ( 210) 152 38.1 0.0082 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 149 37.3 0.009 >>NP_002980 (OMIM: 602737) C-C motif chemokine 21 precur (134 aa) initn: 919 init1: 919 opt: 919 Z-score: 972.0 bits: 185.6 E(85289): 2.1e-47 Smith-Waterman score: 919; 100.0% identity (100.0% similar) in 134 aa overlap (1-134:1-134) 10 20 30 40 50 60 pF1KB6 MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 AILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSK 70 80 90 100 110 120 130 pF1KB6 GCKRTERSQTPKGP :::::::::::::: NP_002 GCKRTERSQTPKGP 130 >>XP_011516306 (OMIM: 602737) PREDICTED: C-C motif chemo (145 aa) initn: 905 init1: 843 opt: 843 Z-score: 892.5 bits: 171.0 E(85289): 5.7e-43 Smith-Waterman score: 887; 92.4% identity (92.4% similar) in 145 aa overlap (1-134:1-145) 10 20 30 40 50 60 pF1KB6 MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 AILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSK 70 80 90 100 110 120 130 pF1KB6 GCK-----------RTERSQTPKGP ::: ::::::::::: XP_011 GCKSQPLTPLFCPHRTERSQTPKGP 130 140 >>NP_006265 (OMIM: 602227) C-C motif chemokine 19 precur (98 aa) initn: 231 init1: 132 opt: 231 Z-score: 258.0 bits: 53.0 E(85289): 1.2e-07 Smith-Waterman score: 231; 37.8% identity (67.3% similar) in 98 aa overlap (1-98:1-94) 10 20 30 40 50 60 pF1KB6 MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIP :: ::::::.: . : .:.. :.::::. .:. ::. .::... . :: .: NP_006 MALLLALSLLVLWTS-PAPTLSGTND-AEDCCLSVTQKPIPGYIVRNFHYLLIKDGCRVP 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 AILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSK :..: . : ::: : . ::....:.:..: . .: NP_006 AVVFTTLRGRQ--LCAPPDQPWVERIIQRLQRTSAKMKRRSS 60 70 80 90 130 pF1KB6 GCKRTERSQTPKGP >>NP_002977 (OMIM: 600807,601156,609423) eotaxin precurs (97 aa) initn: 182 init1: 105 opt: 206 Z-score: 232.0 bits: 48.2 E(85289): 3.5e-06 Smith-Waterman score: 206; 39.8% identity (62.1% similar) in 103 aa overlap (1-99:1-97) 10 20 30 40 50 pF1KB6 MAQSLALSLLILVLAFGIPRTQGSDGGAQ---DCCLKYSQRKIPAKVVRSYRKQEPSLGC : : :: :.:. : : :: : :. ::.. ..:::: . ..:::. : : NP_002 MKVSAALLWLLLIAAAFSP--QGLAGPASVPTTCCFNLANRKIPLQRLESYRRIT-SGKC 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 SIPAILFLPRKRSQAELCADPKELWVQQLMQHLD-KTPSPQKPAQGCRKDRGASKTGKKG :..: . . ..:::::. :::. :..:: :.:.: :: NP_002 PQKAVIF--KTKLAKDICADPKKKWVQDSMKYLDQKSPTP-KP 60 70 80 90 120 130 pF1KB6 KGSKGCKRTERSQTPKGP >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 196 init1: 73 opt: 201 Z-score: 227.1 bits: 47.2 E(85289): 6.5e-06 Smith-Waterman score: 201; 44.3% identity (64.8% similar) in 88 aa overlap (7-91:8-90) 10 20 30 40 50 pF1KB6 MAQSLALSLLILVLAFGIPRTQ---GSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLG ::::.:: :: : . ::: . ::..:. ::.: . : .: : : NP_002 MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTA-CCFSYTARKLPRNFVVDY--YETSSL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKG :: ::..: :::. ..::::.: :::. . :. NP_002 CSQPAVVF-QTKRSK-QVCADPSESWVQEYVYDLELN 60 70 80 90 120 130 pF1KB6 KGSKGCKRTERSQTPKGP >>NP_006264 (OMIM: 158106) C-C motif chemokine 7 precurs (99 aa) initn: 165 init1: 102 opt: 201 Z-score: 226.7 bits: 47.2 E(85289): 6.9e-06 Smith-Waterman score: 201; 35.6% identity (61.4% similar) in 101 aa overlap (1-97:1-98) 10 20 30 40 50 pF1KB6 MAQSLALSLLILVLAFGIPRTQGSDGG---AQDCCLKYSQRKIPAKVVRSYRKQEPSLGC : : :: :.:. : :. .. : . :: .. ..::: . ..:::. : : NP_006 MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSS-HC 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 SIPAILFLPRKRSQAELCADPKELWVQQLMQHLDK-TPSPQKPAQGCRKDRGASKTGKKG :..: . . . :.:::: . :::..:.:::: : .:. NP_006 PREAVIF--KTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL 60 70 80 90 120 130 pF1KB6 KGSKGCKRTERSQTPKGP >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 169 init1: 73 opt: 197 Z-score: 222.9 bits: 46.4 E(85289): 1.1e-05 Smith-Waterman score: 197; 40.9% identity (64.8% similar) in 88 aa overlap (7-91:8-90) 10 20 30 40 50 pF1KB6 MAQSLALSLLILVLAF---GIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLG ::::.:: :: .. .::: . ::..:. ::.: . : .: : : NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTA-CCFSYTARKLPRNFVVDY--YETSSL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKG :: ::..: .. .: .::::.: :::. . :. NP_996 CSQPAVVFQTKRGKQ--VCADPSESWVQEYVYDLELN 60 70 80 90 120 130 pF1KB6 KGSKGCKRTERSQTPKGP >>NP_002973 (OMIM: 158105,182940,607948,609423) C-C moti (99 aa) initn: 178 init1: 103 opt: 193 Z-score: 218.4 bits: 45.7 E(85289): 2e-05 Smith-Waterman score: 193; 36.6% identity (60.4% similar) in 101 aa overlap (1-97:1-98) 10 20 30 40 50 pF1KB6 MAQSLALSLLILVLAFGIPRTQGSDGGAQ---DCCLKYSQRKIPAKVVRSYRKQEPSLGC : : :: :.:. : ::. .. . . :: ....::: .. . :::. : : NP_002 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSS-KC 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 SIPAILFLPRKRSQAELCADPKELWVQQLMQHLDK-TPSPQKPAQGCRKDRGASKTGKKG :..: . :.:::::. :::. :.:::: : .:. NP_002 PKEAVIF--KTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT 60 70 80 90 120 130 pF1KB6 KGSKGCKRTERSQTPKGP >>XP_005258077 (OMIM: 601394) PREDICTED: C-C motif chemo (120 aa) initn: 152 init1: 82 opt: 185 Z-score: 209.0 bits: 44.2 E(85289): 6.7e-05 Smith-Waterman score: 185; 37.5% identity (70.5% similar) in 88 aa overlap (6-88:7-89) 10 20 30 40 50 pF1KB6 MAQSLALSLLILVLAF-GIPRTQGSD----GGAQDCCLKYSQRKIPAKVVRSYRKQEPS :::::.:.: . . :.: . . . ::::: .. .: ..: .::: . XP_005 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRK---A 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 LGCSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGK :.: .:::.:. ::.. :.:..:.. :::. .. XP_005 LNCHLPAIIFVT-KRNR-EVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQ 60 70 80 90 100 110 120 130 pF1KB6 KGKGSKGCKRTERSQTPKGP XP_005 LLNSQ 120 >>NP_004581 (OMIM: 601394) C-C motif chemokine 16 precur (120 aa) initn: 152 init1: 82 opt: 185 Z-score: 209.0 bits: 44.2 E(85289): 6.7e-05 Smith-Waterman score: 185; 37.5% identity (70.5% similar) in 88 aa overlap (6-88:7-89) 10 20 30 40 50 pF1KB6 MAQSLALSLLILVLAF-GIPRTQGSD----GGAQDCCLKYSQRKIPAKVVRSYRKQEPS :::::.:.: . . :.: . . . ::::: .. .: ..: .::: . NP_004 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRK---A 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 LGCSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGK :.: .:::.:. ::.. :.:..:.. :::. .. NP_004 LNCHLPAIIFVT-KRNR-EVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQ 60 70 80 90 100 110 120 130 pF1KB6 KGKGSKGCKRTERSQTPKGP NP_004 LLNSQ 120 134 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:34:39 2016 done: Fri Nov 4 23:34:40 2016 Total Scan time: 4.850 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]