FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6723, 91 aa 1>>>pF1KB6723 91 - 91 aa - 91 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8184+/-0.000272; mu= 11.0919+/- 0.017 mean_var=51.4312+/- 9.985, 0's: 0 Z-trim(119.0): 68 B-trim: 0 in 0/55 Lambda= 0.178838 statistics sampled from 32521 (32591) to 32521 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.382), width: 16 Scan time: 3.840 The best scores are: opt bits E(85289) NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 609 163.9 3.3e-41 NP_001265665 (OMIM: 187011) C-C motif chemokine 5 ( 154) 423 116.0 1.4e-26 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 338 94.0 3.7e-20 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 338 94.0 3.7e-20 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 332 92.4 1.1e-19 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 325 90.6 3.7e-19 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 308 86.2 7.8e-18 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 272 76.9 4.7e-15 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 248 70.8 3.6e-13 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 246 70.2 5e-13 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 238 68.2 2.2e-12 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 231 66.4 7.6e-12 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 231 66.4 7.6e-12 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 231 66.5 1.1e-11 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 225 64.8 2.3e-11 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 222 64.1 4.3e-11 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 219 63.3 8.1e-11 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 219 63.3 8.1e-11 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 217 62.8 9.8e-11 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 215 62.3 1.4e-10 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 207 60.2 5.7e-10 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 201 58.6 1.6e-09 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 201 58.6 1.6e-09 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 199 58.1 2.5e-09 NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 195 57.0 3.4e-09 NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 195 57.0 3.4e-09 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 196 57.4 4.3e-09 NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 195 57.1 4.4e-09 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 194 56.8 6e-09 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 190 55.8 1.4e-08 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 189 55.6 1.9e-08 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 188 55.3 2.1e-08 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 184 54.3 3.5e-08 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 167 49.9 8.7e-07 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 167 49.9 8.7e-07 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 167 49.9 8.7e-07 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 165 49.3 1e-06 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 165 49.4 1.3e-06 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 165 49.4 1.3e-06 XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 153 46.3 1e-05 NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 153 46.3 1e-05 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 153 46.3 1.2e-05 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 153 46.3 1.3e-05 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 151 45.7 1.3e-05 NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 151 45.8 1.5e-05 NP_954637 (OMIM: 600835,609423) stromal cell-deriv ( 89) 147 44.7 2.4e-05 NP_000600 (OMIM: 600835,609423) stromal cell-deriv ( 93) 147 44.7 2.5e-05 NP_001029058 (OMIM: 600835,609423) stromal cell-de ( 119) 147 44.7 3.1e-05 NP_001171605 (OMIM: 600835,609423) stromal cell-de ( 140) 147 44.8 3.6e-05 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 141 43.2 7.6e-05 >>NP_002976 (OMIM: 187011) C-C motif chemokine 5 isoform (91 aa) initn: 609 init1: 609 opt: 609 Z-score: 860.9 bits: 163.9 E(85289): 3.3e-41 Smith-Waterman score: 609; 100.0% identity (100.0% similar) in 91 aa overlap (1-91:1-91) 10 20 30 40 50 60 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNP 10 20 30 40 50 60 70 80 90 pF1KB6 AVVFVTRKNRQVCANPEKKWVREYINSLEMS ::::::::::::::::::::::::::::::: NP_002 AVVFVTRKNRQVCANPEKKWVREYINSLEMS 70 80 90 >>NP_001265665 (OMIM: 187011) C-C motif chemokine 5 isof (154 aa) initn: 423 init1: 423 opt: 423 Z-score: 598.0 bits: 116.0 E(85289): 1.4e-26 Smith-Waterman score: 423; 95.5% identity (97.0% similar) in 67 aa overlap (1-67:1-67) 10 20 30 40 50 60 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNP 10 20 30 40 50 60 70 80 90 pF1KB6 AVVFVTRKNRQVCANPEKKWVREYINSLEMS ::: .: NP_001 AVVHRSRMPKREGQQVWQDFLYDSRLNKGKLCHPKEPPSVCQPREEMGSGVHQLFGDELG 70 80 90 100 110 120 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 339 init1: 260 opt: 338 Z-score: 482.9 bits: 94.0 E(85289): 3.7e-20 Smith-Waterman score: 338; 48.9% identity (83.7% similar) in 92 aa overlap (1-91:1-92) 10 20 30 40 50 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDT-TPCCFAYIARPLPRAHIKEYFYTSGKCSN :.::.:::::.: . ::: . ..: ..:: : :::.: .: .:. : .:: ::..::. NP_066 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 60 70 80 90 pF1KB6 PAVVFVTRKNRQVCANPEKKWVREYINSLEMS :.:.:.:...:::::.: ..::..:...::.: NP_066 PSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 339 init1: 260 opt: 338 Z-score: 482.9 bits: 94.0 E(85289): 3.7e-20 Smith-Waterman score: 338; 48.9% identity (83.7% similar) in 92 aa overlap (1-91:1-92) 10 20 30 40 50 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDT-TPCCFAYIARPLPRAHIKEYFYTSGKCSN :.::.:::::.: . ::: . ..: ..:: : :::.: .: .:. : .:: ::..::. NP_001 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 60 70 80 90 pF1KB6 PAVVFVTRKNRQVCANPEKKWVREYINSLEMS :.:.:.:...:::::.: ..::..:...::.: NP_001 PSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa) initn: 344 init1: 323 opt: 332 Z-score: 474.6 bits: 92.4 E(85289): 1.1e-19 Smith-Waterman score: 332; 49.5% identity (81.3% similar) in 91 aa overlap (1-91:1-91) 10 20 30 40 50 60 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNP :.::.:::::.: . ::: ::: .. : :::.: .: .:. : .:: ::..::.: NP_002 MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKP 10 20 30 40 50 60 70 80 90 pF1KB6 AVVFVTRKNRQVCANPEKKWVREYINSLEMS .:.:.:...:::::.: ..::..:...::.: NP_002 GVIFLTKRSRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 359 init1: 260 opt: 325 Z-score: 464.8 bits: 90.6 E(85289): 3.7e-19 Smith-Waterman score: 325; 45.7% identity (83.7% similar) in 92 aa overlap (1-91:1-92) 10 20 30 40 50 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDT-TPCCFAYIARPLPRAHIKEYFYTSGKCSN ::. ...:.......:.:.:: ..:..:: : :::.: :: ::: . .:. ::. ::. NP_002 MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 60 70 80 90 pF1KB6 PAVVFVTRKNRQVCANPEKKWVREYINSLEMS ::::: :....::::.: ..::.::. .::.. NP_002 PAVVFQTKRSKQVCADPSESWVQEYVYDLELN 70 80 90 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 349 init1: 259 opt: 308 Z-score: 441.1 bits: 86.2 E(85289): 7.8e-18 Smith-Waterman score: 308; 44.6% identity (82.6% similar) in 92 aa overlap (1-91:1-92) 10 20 30 40 50 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDT-TPCCFAYIARPLPRAHIKEYFYTSGKCSN ::. ...:.......:.:. : ..:..:: : :::.: :: ::: . .:. ::. ::. NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 60 70 80 90 pF1KB6 PAVVFVTRKNRQVCANPEKKWVREYINSLEMS ::::: :....::::.: ..::.::. .::.. NP_996 PAVVFQTKRGKQVCADPSESWVQEYVYDLELN 70 80 90 >>NP_001278397 (OMIM: 610757) C-C motif chemokine 4-like (87 aa) initn: 226 init1: 146 opt: 272 Z-score: 391.3 bits: 76.9 E(85289): 4.7e-15 Smith-Waterman score: 272; 42.4% identity (78.3% similar) in 92 aa overlap (1-91:1-87) 10 20 30 40 50 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDT-TPCCFAYIARPLPRAHIKEYFYTSGKCSN ::. ...:.......:.:. : ..:..:: : :::.: :: ::: . .:. ::. ::. NP_001 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 60 70 80 90 pF1KB6 PAVVFVTRKNRQVCANPEKKWVREYINSLEMS :::: ..::::.: ..::.::. .::.. NP_001 PAVV-----GKQVCADPSESWVQEYVYDLELN 70 80 >>NP_116739 (OMIM: 601392) C-C motif chemokine 14 isofor (93 aa) initn: 256 init1: 219 opt: 248 Z-score: 357.4 bits: 70.8 E(85289): 3.6e-13 Smith-Waterman score: 248; 36.3% identity (72.5% similar) in 91 aa overlap (1-89:1-91) 10 20 30 40 50 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDTTP--CCFAYIARPLPRAHIKEYFYTSGKCS ::.:.::. .:. : . . : . : :::.: . .:: .: .:. :...:: NP_116 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS 10 20 30 40 50 60 60 70 80 90 pF1KB6 NPAVVFVTRKNRQVCANPEKKWVREYINSLEMS .:..::.:.....::.:: :::..::.... NP_116 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 70 80 90 >>NP_002979 (OMIM: 603757) C-C motif chemokine 18 precur (89 aa) initn: 249 init1: 209 opt: 246 Z-score: 354.9 bits: 70.2 E(85289): 5e-13 Smith-Waterman score: 246; 38.5% identity (73.6% similar) in 91 aa overlap (1-91:1-88) 10 20 30 40 50 60 pF1KB6 MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNP :: :::: :.. . ::: : . ... ::..: . .:. : .: :: .: .: NP_002 MKGLAAALLVLVCTMALC---SCAQVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKP 10 20 30 40 50 70 80 90 pF1KB6 AVVFVTRKNRQVCANPEKKWVREYINSLEMS .:...:...::.::.:.::::..::..:... NP_002 GVILLTKRGRQICADPNKKWVQKYISDLKLNA 60 70 80 91 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:35:44 2016 done: Fri Nov 4 23:35:45 2016 Total Scan time: 3.840 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]