Result of FASTA (omim) for
pF1KB6724
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6724, 135 aa
1>>>pF1KB6724 135 - 135 aa - 135 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5021+/-0.000337; mu= 15.4679+/- 0.021
mean_var=55.5263+/-11.147, 0's: 0 Z-trim(113.7): 28 B-trim: 85 in 1/54
Lambda= 0.172117
statistics sampled from 23091 (23118) to 23091 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.271), width: 16
Scan time: 3.460
The best scores are: opt bits E(85289)
NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 927 237.9 5.7e-63
NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 566 148.1 4.6e-36
NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 565 147.9 5.4e-36
NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 562 147.1 8.1e-36
NP_113679 (OMIM: 611866) retinol-binding protein 5 ( 135) 548 143.6 9.1e-35
NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 495 130.5 8.3e-31
XP_016875491 (OMIM: 611866) PREDICTED: retinol-bin ( 126) 472 124.7 4.1e-29
NP_001316383 (OMIM: 611866) retinol-binding protei ( 86) 364 97.8 3.6e-21
NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 338 91.5 4.6e-19
NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 338 91.5 4.6e-19
XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 338 91.5 4.6e-19
NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 335 90.7 7.7e-19
NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 324 88.0 4.9e-18
NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 315 85.8 2.8e-17
NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 305 83.3 1.3e-16
NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 281 77.3 8.1e-15
NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 272 75.1 3.8e-14
NP_001305970 (OMIM: 602965) fatty acid-binding pro ( 97) 260 72.0 2.4e-13
XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 260 72.1 2.9e-13
NP_001305971 (OMIM: 602965) fatty acid-binding pro ( 128) 250 69.6 1.6e-12
NP_001435 (OMIM: 605168) fatty acid-binding protei ( 135) 234 65.7 2.7e-11
NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 197 56.5 1.5e-08
NP_001307925 (OMIM: 134651) fatty acid-binding pro ( 144) 197 56.5 1.6e-08
NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 152 45.3 3.4e-05
>>NP_002890 (OMIM: 180260) retinol-binding protein 1 iso (197 aa)
initn: 927 init1: 927 opt: 927 Z-score: 1251.5 bits: 237.9 E(85289): 5.7e-63
Smith-Waterman score: 927; 100.0% identity (100.0% similar) in 135 aa overlap (1-135:63-197)
10 20 30
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVAL
::::::::::::::::::::::::::::::
NP_002 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB6 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWD
100 110 120 130 140 150
100 110 120 130
pF1KB6 GDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
:::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
160 170 180 190
>>NP_001124464 (OMIM: 180260) retinol-binding protein 1 (157 aa)
initn: 583 init1: 566 opt: 566 Z-score: 768.4 bits: 148.1 E(85289): 4.6e-36
Smith-Waterman score: 566; 97.7% identity (98.9% similar) in 87 aa overlap (1-87:63-149)
10 20 30
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVAL
::::::::::::::::::::::::::::::
NP_001 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB6 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::. :
NP_001 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMAGVQSR
100 110 120 130 140 150
100 110 120 130
pF1KB6 GDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
NP_001 DLSSL
>>NP_001124465 (OMIM: 180260) retinol-binding protein 1 (153 aa)
initn: 582 init1: 565 opt: 565 Z-score: 767.3 bits: 147.9 E(85289): 5.4e-36
Smith-Waterman score: 565; 98.8% identity (100.0% similar) in 85 aa overlap (1-85:63-147)
10 20 30
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVAL
::::::::::::::::::::::::::::::
NP_001 HHPRSTGSRCPGSLQPSRPLVANWLQSLPEMPVDFTGYWKMLVNENFEEYLRALDVNVAL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB6 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 RKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMSETGFS
100 110 120 130 140 150
100 110 120 130
pF1KB6 GDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
NP_001 S
>>NP_443192 (OMIM: 608604) retinoid-binding protein 7 [H (134 aa)
initn: 587 init1: 562 opt: 562 Z-score: 764.0 bits: 147.1 E(85289): 8.1e-36
Smith-Waterman score: 562; 57.1% identity (82.7% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRN
::.:..: : .: ..::: :. :: .. : ::::.::::.: : :.:: . :.: :..::
NP_443 MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQKGEKEGRGWTQWIEGDELHLEM
:.. :.::.::.:: :.:.::: . : ::.:.: :.:::::..::::.:::::.:::::
NP_443 YFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEM
70 80 90 100 110 120
130
pF1KB6 RVEGVVCKQVFKKVQ
:: ::::.:..
NP_443 FCEGQVCKQTFQRA
130
>>NP_113679 (OMIM: 611866) retinol-binding protein 5 iso (135 aa)
initn: 584 init1: 548 opt: 548 Z-score: 745.2 bits: 143.6 E(85289): 9.1e-35
Smith-Waterman score: 548; 55.6% identity (86.7% similar) in 135 aa overlap (1-135:1-135)
10 20 30 40 50 60
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRN
:: ..:::.... ..:.:.::.::....:.:::: :::::::: ..:.:: .::::::::
NP_113 MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQKGEKEGRGWTQWIEGDELHLEM
: ..:.:: :::::: ..: :::.: :.:. ..: :::::: .::: .:.::. :.::.
NP_113 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
70 80 90 100 110 120
130
pF1KB6 RVEGVVCKQVFKKVQ
.. .::.:::.::.
NP_113 TARDAVCEQVFRKVR
130
>>NP_004155 (OMIM: 180280) retinol-binding protein 2 [Ho (134 aa)
initn: 464 init1: 464 opt: 495 Z-score: 674.1 bits: 130.5 E(85289): 8.3e-31
Smith-Waterman score: 495; 55.6% identity (72.9% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRN
: : .: :.: ::::: :..:::.. : :::: : : : ::::.. .: :::::
NP_004 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQKGEKEGRGWTQWIEGDELHLEM
: .:: :: ::.: ..:.:. . :.:.:: : ::::::::.::: ::::::.:.::.
NP_004 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRGWKQWIEGDKLYLEL
70 80 90 100 110 120
130
pF1KB6 RVEGVVCKQVFKKVQ
::.:::::
NP_004 TCGDQVCRQVFKKK
130
>>XP_016875491 (OMIM: 611866) PREDICTED: retinol-binding (126 aa)
initn: 477 init1: 452 opt: 472 Z-score: 643.6 bits: 124.7 E(85289): 4.1e-29
Smith-Waterman score: 472; 58.6% identity (85.6% similar) in 111 aa overlap (25-135:16-126)
10 20 30 40 50 60
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRN
:...:.:::: :::::::: ..:.:: .::::::::
XP_016 MMNQAQWILKPGTMADISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 YIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQKGEKEGRGWTQWIEGDELHLEM
: ..:.:: :::::: ..: :::.: :.:. ..: :::::: .::: .:.::. :.::.
XP_016 YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
60 70 80 90 100 110
130
pF1KB6 RVEGVVCKQVFKKVQ
.. .::.:::.::.
XP_016 TARDAVCEQVFRKVR
120
>>NP_001316383 (OMIM: 611866) retinol-binding protein 5 (86 aa)
initn: 390 init1: 354 opt: 364 Z-score: 501.0 bits: 97.8 E(85289): 3.6e-21
Smith-Waterman score: 364; 57.0% identity (83.7% similar) in 86 aa overlap (50-135:1-86)
20 30 40 50 60 70
pF1KB6 YLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGID
: .::::::::: ..:.:: :::::: ..:
NP_001 MTVRTLSTFRNYTVQFDVGVEFEEDLRSVD
10 20 30
80 90 100 110 120 130
pF1KB6 DRKCMTTVSWDGDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
:::.: :.:. ..: :::::: .::: .:.::. :.::. .. .::.:::.::.
NP_001 GRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
40 50 60 70 80
>>NP_001869 (OMIM: 180231) cellular retinoic acid-bindin (138 aa)
initn: 290 init1: 129 opt: 338 Z-score: 463.2 bits: 91.5 E(85289): 4.6e-19
Smith-Waterman score: 338; 44.2% identity (67.4% similar) in 138 aa overlap (1-131:1-135)
10 20 30 40 50
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIA--NLLKPDKEIVQDGDHMIIRTLSTF
:: .:.: ::.. .::::: :..: ::: ::::: :: :: :.:: . :.: .:
NP_001 MP-NFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTV
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 RNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGD-KLQCVQK---GEKEGRGWTQWIEGD
:. ..:.::.::::. .: : : . :.:... :. : :: :: .::. . .:
NP_001 RTTEINFKVGEEFEEQT--VDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTND
60 70 80 90 100 110
120 130
pF1KB6 -ELHLEMRVEGVVCKQVFKKVQ
:: : : .. ::: .:.
NP_001 GELILTMTADDVVCTRVYVRE
120 130
>>NP_001186652 (OMIM: 180231) cellular retinoic acid-bin (138 aa)
initn: 290 init1: 129 opt: 338 Z-score: 463.2 bits: 91.5 E(85289): 4.6e-19
Smith-Waterman score: 338; 44.2% identity (67.4% similar) in 138 aa overlap (1-131:1-135)
10 20 30 40 50
pF1KB6 MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIA--NLLKPDKEIVQDGDHMIIRTLSTF
:: .:.: ::.. .::::: :..: ::: ::::: :: :: :.:: . :.: .:
NP_001 MP-NFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTV
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 RNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGD-KLQCVQK---GEKEGRGWTQWIEGD
:. ..:.::.::::. .: : : . :.:... :. : :: :: .::. . .:
NP_001 RTTEINFKVGEEFEEQT--VDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTND
60 70 80 90 100 110
120 130
pF1KB6 -ELHLEMRVEGVVCKQVFKKVQ
:: : : .. ::: .:.
NP_001 GELILTMTADDVVCTRVYVRE
120 130
135 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:36:17 2016 done: Fri Nov 4 23:36:18 2016
Total Scan time: 3.460 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]