FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6725, 92 aa 1>>>pF1KB6725 92 - 92 aa - 92 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7127+/-0.000298; mu= 11.5933+/- 0.018 mean_var=50.9131+/-10.418, 0's: 0 Z-trim(117.2): 66 B-trim: 1270 in 1/54 Lambda= 0.179746 statistics sampled from 28926 (28996) to 28926 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.34), width: 16 Scan time: 3.630 The best scores are: opt bits E(85289) NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 612 165.6 1e-41 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 574 155.8 9.5e-39 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 574 155.8 9.5e-39 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 395 109.3 8.8e-25 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 388 107.5 3.1e-24 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 375 104.1 3.1e-23 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 344 96.1 8.1e-21 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 332 93.0 7.2e-20 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 318 89.4 9.1e-19 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 290 82.1 1.6e-16 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 251 72.0 1.6e-13 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 243 69.9 7.1e-13 NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 239 68.8 9.8e-13 NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 239 68.8 9.8e-13 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 241 69.4 1e-12 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 240 69.2 1.2e-12 NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 239 68.9 1.3e-12 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 240 69.2 1.4e-12 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 240 69.2 1.6e-12 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 237 68.4 1.9e-12 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 237 68.4 1.9e-12 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 237 68.5 2.8e-12 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 235 67.9 3.2e-12 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 232 67.1 5.9e-12 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 232 67.1 5.9e-12 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 225 65.3 1.7e-11 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 223 64.8 2.9e-11 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 223 64.8 2.9e-11 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 223 64.8 2.9e-11 NP_001265665 (OMIM: 187011) C-C motif chemokine 5 ( 154) 224 65.1 3e-11 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 218 63.4 6.1e-11 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 216 62.9 8.8e-11 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 214 62.4 1.3e-10 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 189 55.9 1.1e-08 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 189 55.9 1.1e-08 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 178 53.1 8e-08 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 175 52.4 1.8e-07 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 175 52.4 1.9e-07 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 164 49.4 1e-06 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 163 49.2 1.2e-06 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 163 49.2 1.4e-06 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 163 49.2 1.5e-06 NP_004582 (OMIM: 601960) C-C motif chemokine 20 is ( 96) 151 46.1 1e-05 NP_001123518 (OMIM: 601960) C-C motif chemokine 20 ( 95) 146 44.8 2.5e-05 NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 140 43.3 8.5e-05 XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 140 43.3 8.5e-05 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 138 42.7 0.00011 NP_002987 (OMIM: 601880) fractalkine isoform 1 pre ( 397) 141 43.8 0.0002 NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 135 42.0 0.00021 >>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa) initn: 612 init1: 612 opt: 612 Z-score: 870.0 bits: 165.6 E(85289): 1e-41 Smith-Waterman score: 612; 100.0% identity (100.0% similar) in 92 aa overlap (1-92:1-92) 10 20 30 40 50 60 pF1KB6 MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKP 10 20 30 40 50 60 70 80 90 pF1KB6 GVIFLTKRSRQVCADPSEEWVQKYVSDLELSA :::::::::::::::::::::::::::::::: NP_002 GVIFLTKRSRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 572 init1: 460 opt: 574 Z-score: 816.7 bits: 155.8 E(85289): 9.5e-39 Smith-Waterman score: 574; 94.6% identity (97.8% similar) in 93 aa overlap (1-92:1-93) 10 20 30 40 50 pF1KB6 MQVSTAALAVLLCTMALCNQ-FSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK :::::::::::::::::::: .:: ::::::::::::::::::::::::::::::::::: NP_001 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 60 70 80 90 pF1KB6 PGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA :.:::::::.::::::::::::::::::::::: NP_001 PSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 572 init1: 460 opt: 574 Z-score: 816.7 bits: 155.8 E(85289): 9.5e-39 Smith-Waterman score: 574; 94.6% identity (97.8% similar) in 93 aa overlap (1-92:1-93) 10 20 30 40 50 pF1KB6 MQVSTAALAVLLCTMALCNQ-FSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK :::::::::::::::::::: .:: ::::::::::::::::::::::::::::::::::: NP_066 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 60 70 80 90 pF1KB6 PGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA :.:::::::.::::::::::::::::::::::: NP_066 PSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 388 init1: 366 opt: 395 Z-score: 565.9 bits: 109.3 E(85289): 8.8e-25 Smith-Waterman score: 395; 57.6% identity (88.0% similar) in 92 aa overlap (1-91:1-92) 10 20 30 40 50 pF1KB6 MQVSTAALAVLLCTMALCNQ-FSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK :.. ...:..:. . :.:. .:: ...: :::::::::.:..:.::..::.:::: ::. NP_002 MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 60 70 80 90 pF1KB6 PGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA :.:.: ::::.:::::::: :::.:: ::::. NP_002 PAVVFQTKRSKQVCADPSESWVQEYVYDLELN 70 80 90 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 383 init1: 361 opt: 388 Z-score: 556.1 bits: 107.5 E(85289): 3.1e-24 Smith-Waterman score: 388; 56.5% identity (88.0% similar) in 92 aa overlap (1-91:1-92) 10 20 30 40 50 pF1KB6 MQVSTAALAVLLCTMALCN-QFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK :.. ...:..:. . :.:. .:: ...: :::::::::.:..:.::..::.:::: ::. NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 60 70 80 90 pF1KB6 PGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA :.:.: :::..:::::::: :::.:: ::::. NP_996 PAVVFQTKRGKQVCADPSESWVQEYVYDLELN 70 80 90 >>NP_002979 (OMIM: 603757) C-C motif chemokine 18 precur (89 aa) initn: 378 init1: 319 opt: 375 Z-score: 538.1 bits: 104.1 E(85289): 3.1e-23 Smith-Waterman score: 375; 60.9% identity (81.5% similar) in 92 aa overlap (1-92:1-89) 10 20 30 40 50 60 pF1KB6 MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKP :. .::: ::.:::::: : . .. . ::. ::: ::::.::.:: ::: :: :: NP_002 MKGLAAALLVLVCTMALC---SCAQVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKP 10 20 30 40 50 70 80 90 pF1KB6 GVIFLTKRSRQVCADPSEEWVQKYVSDLELSA :::.::::.::.::::...:::::.:::.:.: NP_002 GVILLTKRGRQICADPNKKWVQKYISDLKLNA 60 70 80 >>NP_001278397 (OMIM: 610757) C-C motif chemokine 4-like (87 aa) initn: 342 init1: 212 opt: 344 Z-score: 494.8 bits: 96.1 E(85289): 8.1e-21 Smith-Waterman score: 344; 52.2% identity (83.7% similar) in 92 aa overlap (1-91:1-87) 10 20 30 40 50 pF1KB6 MQVSTAALAVLLCTMALCN-QFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK :.. ...:..:. . :.:. .:: ...: :::::::::.:..:.::..::.:::: ::. NP_001 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 60 70 80 90 pF1KB6 PGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA :.:. ..:::::::: :::.:: ::::. NP_001 PAVV-----GKQVCADPSESWVQEYVYDLELN 70 80 >>NP_002976 (OMIM: 187011) C-C motif chemokine 5 isoform (91 aa) initn: 344 init1: 323 opt: 332 Z-score: 477.7 bits: 93.0 E(85289): 7.2e-20 Smith-Waterman score: 332; 49.5% identity (81.3% similar) in 91 aa overlap (1-91:1-91) 10 20 30 40 50 60 pF1KB6 MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKP :.::.:::::.: . ::: ::: .. : :::.: .: .:. : .:: ::..::.: NP_002 MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNP 10 20 30 40 50 60 70 80 90 pF1KB6 GVIFLTKRSRQVCADPSEEWVQKYVSDLELSA .:.:.:...:::::.: ..::..:...::.: NP_002 AVVFVTRKNRQVCANPEKKWVREYINSLEMS 70 80 90 >>NP_116739 (OMIM: 601392) C-C motif chemokine 14 isofor (93 aa) initn: 299 init1: 279 opt: 318 Z-score: 457.9 bits: 89.4 E(85289): 9.1e-19 Smith-Waterman score: 318; 48.4% identity (82.4% similar) in 91 aa overlap (1-89:1-91) 10 20 30 40 50 pF1KB6 MQVSTAALAV-LLCTMALCNQF-SASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCS :..:.::. :: :.:: .. :.: . :. :::.::. .::.. : ::.::.:::: NP_116 MKISVAAIPFFLLITIALGTKTESSSRGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCS 10 20 30 40 50 60 60 70 80 90 pF1KB6 KPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA :::..:.:::...::..::..::: :..:.. NP_116 KPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 70 80 90 >>NP_116738 (OMIM: 601392) C-C motif chemokine 14 isofor (109 aa) initn: 292 init1: 279 opt: 290 Z-score: 417.6 bits: 82.1 E(85289): 1.6e-16 Smith-Waterman score: 290; 55.0% identity (91.7% similar) in 60 aa overlap (30-89:48-107) 10 20 30 40 50 pF1KB6 MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK :. :::.::. .::.. : ::.::.::::: NP_116 LGTKTESSSQTGGKPKVVKIQLKLVGGPYHPSECCFTYTTYKIPRQRIMDYYETNSQCSK 20 30 40 50 60 70 60 70 80 90 pF1KB6 PGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA ::..:.:::...::..::..::: :..:.. NP_116 PGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 80 90 100 92 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:36:50 2016 done: Fri Nov 4 23:36:51 2016 Total Scan time: 3.630 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]