FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6729, 92 aa 1>>>pF1KB6729 92 - 92 aa - 92 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8288+/-0.000334; mu= 10.4860+/- 0.021 mean_var=49.0663+/- 9.904, 0's: 0 Z-trim(113.2): 26 B-trim: 1179 in 1/54 Lambda= 0.183098 statistics sampled from 22424 (22449) to 22424 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.263), width: 16 Scan time: 3.130 The best scores are: opt bits E(85289) NP_003085 (OMIM: 128260,615059) small nuclear ribo ( 92) 601 166.0 7.6e-42 NP_001315566 (OMIM: 128260,615059) small nuclear r ( 90) 494 137.8 2.4e-33 NP_001291393 (OMIM: 128260,615059) small nuclear r ( 84) 481 134.3 2.4e-32 NP_001315567 (OMIM: 128260,615059) small nuclear r ( 79) 427 120.0 4.5e-28 NP_036454 (OMIM: 607285) U6 snRNA-associated Sm-li ( 91) 136 43.2 7.1e-05 NP_001124182 (OMIM: 607285) U6 snRNA-associated Sm ( 62) 126 40.5 0.00032 NP_001132971 (OMIM: 607285) U6 snRNA-associated Sm ( 62) 126 40.5 0.00032 NP_001304100 (OMIM: 603542) small nuclear ribonucl ( 58) 111 36.5 0.0046 NP_001304097 (OMIM: 603542) small nuclear ribonucl ( 64) 111 36.5 0.0051 NP_001304098 (OMIM: 603542) small nuclear ribonucl ( 64) 111 36.5 0.0051 NP_001304096 (OMIM: 603542) small nuclear ribonucl ( 68) 111 36.5 0.0053 NP_003087 (OMIM: 603542) small nuclear ribonucleop ( 76) 111 36.6 0.0059 >>NP_003085 (OMIM: 128260,615059) small nuclear ribonucl (92 aa) initn: 601 init1: 601 opt: 601 Z-score: 872.3 bits: 166.0 E(85289): 7.6e-42 Smith-Waterman score: 601; 100.0% identity (100.0% similar) in 92 aa overlap (1-92:1-92) 10 20 30 40 50 60 pF1KB6 MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDD 10 20 30 40 50 60 70 80 90 pF1KB6 AEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN :::::::::::::::::::::::::::::::: NP_003 AEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN 70 80 90 >>NP_001315566 (OMIM: 128260,615059) small nuclear ribon (90 aa) initn: 481 init1: 481 opt: 494 Z-score: 719.7 bits: 137.8 E(85289): 2.4e-33 Smith-Waterman score: 494; 86.8% identity (94.5% similar) in 91 aa overlap (2-92:3-90) 10 20 30 40 50 pF1KB6 MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLD : .: :.... ..:: ::::::::::::::::::::::::::::::::::::::::: NP_001 MDAAKG-GKRTSATVVQ--NLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLD 10 20 30 40 50 60 70 80 90 pF1KB6 DAEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN ::::::::::::::::::::::::::::::::: NP_001 DAEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN 60 70 80 90 >>NP_001291393 (OMIM: 128260,615059) small nuclear ribon (84 aa) initn: 481 init1: 481 opt: 481 Z-score: 701.6 bits: 134.3 E(85289): 2.4e-32 Smith-Waterman score: 481; 100.0% identity (100.0% similar) in 74 aa overlap (19-92:11-84) 10 20 30 40 50 60 pF1KB6 MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDD :::::::::::::::::::::::::::::::::::::::::: NP_001 MSGLGATVVQNLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDD 10 20 30 40 50 70 80 90 pF1KB6 AEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN :::::::::::::::::::::::::::::::: NP_001 AEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN 60 70 80 >>NP_001315567 (OMIM: 128260,615059) small nuclear ribon (79 aa) initn: 422 init1: 422 opt: 427 Z-score: 624.9 bits: 120.0 E(85289): 4.5e-28 Smith-Waterman score: 427; 97.1% identity (97.1% similar) in 70 aa overlap (23-92:11-79) 10 20 30 40 50 60 pF1KB6 MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDD : :: ::::::::::::::::::::::::::::::::: NP_001 MQEWTRQKEGRELQ-RSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDD 10 20 30 40 70 80 90 pF1KB6 AEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN :::::::::::::::::::::::::::::::: NP_001 AEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN 50 60 70 >>NP_036454 (OMIM: 607285) U6 snRNA-associated Sm-like p (91 aa) initn: 138 init1: 66 opt: 136 Z-score: 208.5 bits: 43.2 E(85289): 7.1e-05 Smith-Waterman score: 136; 32.9% identity (74.0% similar) in 73 aa overlap (17-87:14-82) 10 20 30 40 50 60 pF1KB6 MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDD :..:. . . :::.. . . . .: : ..:::...:.::.: NP_036 MAANATTNPSQLLPLELVDKCIG--SRIHIVM--KSDKEIVGTLLGFDDFVNMVLED 10 20 30 40 50 70 80 90 pF1KB6 AEEIHSKTKSRK--QLGRIMLKGDNITLLQSVSN . :.. ..:. .: .:.:.:.:::.: NP_036 VTEFEITPEGRRITKLDQILLNGNNITMLVPGGEGPEV 60 70 80 90 >>NP_001124182 (OMIM: 607285) U6 snRNA-associated Sm-lik (62 aa) initn: 138 init1: 66 opt: 126 Z-score: 196.9 bits: 40.5 E(85289): 0.00032 Smith-Waterman score: 126; 40.4% identity (80.9% similar) in 47 aa overlap (43-87:7-53) 20 30 40 50 60 70 pF1KB6 VMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRK : : ..:::...:.::.:. :.. ..:. NP_001 MKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRR 10 20 30 80 90 pF1KB6 --QLGRIMLKGDNITLLQSVSN .: .:.:.:.:::.: NP_001 ITKLDQILLNGNNITMLVPGGEGPEV 40 50 60 >>NP_001132971 (OMIM: 607285) U6 snRNA-associated Sm-lik (62 aa) initn: 138 init1: 66 opt: 126 Z-score: 196.9 bits: 40.5 E(85289): 0.00032 Smith-Waterman score: 126; 40.4% identity (80.9% similar) in 47 aa overlap (43-87:7-53) 20 30 40 50 60 70 pF1KB6 VMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRK : : ..:::...:.::.:. :.. ..:. NP_001 MKSDKEIVGTLLGFDDFVNMVLEDVTEFEITPEGRR 10 20 30 80 90 pF1KB6 --QLGRIMLKGDNITLLQSVSN .: .:.:.:.:::.: NP_001 ITKLDQILLNGNNITMLVPGGEGPEV 40 50 60 >>NP_001304100 (OMIM: 603542) small nuclear ribonucleopr (58 aa) initn: 71 init1: 67 opt: 111 Z-score: 175.9 bits: 36.5 E(85289): 0.0046 Smith-Waterman score: 111; 29.2% identity (79.2% similar) in 48 aa overlap (43-90:9-55) 20 30 40 50 60 70 pF1KB6 VMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRK ..: . ::: .::::.:. :. .. . .. NP_001 MKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQ-QN 10 20 30 80 90 pF1KB6 QLGRIMLKGDNITLLQSVSN ..: ....:..: .:... NP_001 NIGMVVIRGNSIIMLEALERV 40 50 >>NP_001304097 (OMIM: 603542) small nuclear ribonucleopr (64 aa) initn: 67 init1: 67 opt: 111 Z-score: 175.2 bits: 36.5 E(85289): 0.0051 Smith-Waterman score: 111; 29.2% identity (79.2% similar) in 48 aa overlap (43-90:15-61) 20 30 40 50 60 70 pF1KB6 VMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRK ..: . ::: .::::.:. :. .. . .. NP_001 MDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQ-QN 10 20 30 40 80 90 pF1KB6 QLGRIMLKGDNITLLQSVSN ..: ....:..: .:... NP_001 NIGMVVIRGNSIIMLEALERV 50 60 >>NP_001304098 (OMIM: 603542) small nuclear ribonucleopr (64 aa) initn: 67 init1: 67 opt: 111 Z-score: 175.2 bits: 36.5 E(85289): 0.0051 Smith-Waterman score: 111; 29.2% identity (79.2% similar) in 48 aa overlap (43-90:15-61) 20 30 40 50 60 70 pF1KB6 VMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRK ..: . ::: .::::.:. :. .. . .. NP_001 MDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQ-QN 10 20 30 40 80 90 pF1KB6 QLGRIMLKGDNITLLQSVSN ..: ....:..: .:... NP_001 NIGMVVIRGNSIIMLEALERV 50 60 92 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:39:53 2016 done: Fri Nov 4 23:39:54 2016 Total Scan time: 3.130 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]