FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6732, 130 aa 1>>>pF1KB6732 130 - 130 aa - 130 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7585+/-0.000312; mu= 14.4012+/- 0.019 mean_var=69.7646+/-14.792, 0's: 0 Z-trim(117.7): 32 B-trim: 579 in 1/53 Lambda= 0.153552 statistics sampled from 29914 (29961) to 29914 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.351), width: 16 Scan time: 4.440 The best scores are: opt bits E(85289) NP_002029 (OMIM: 147572) interferon alpha-inducibl ( 130) 840 194.1 5.2e-50 NP_075010 (OMIM: 147572) interferon alpha-inducibl ( 134) 822 190.2 8.4e-49 NP_075011 (OMIM: 147572) interferon alpha-inducibl ( 138) 814 188.4 2.9e-48 NP_114425 (OMIM: 611319) interferon alpha-inducibl ( 130) 268 67.4 7.2e-12 NP_660292 (OMIM: 611320) interferon alpha-inducibl ( 104) 249 63.1 1.1e-10 XP_011534707 (OMIM: 611320) PREDICTED: interferon ( 104) 249 63.1 1.1e-10 NP_996832 (OMIM: 611320) interferon alpha-inducibl ( 104) 249 63.1 1.1e-10 XP_016876450 (OMIM: 611320) PREDICTED: interferon ( 124) 249 63.2 1.3e-10 XP_005267371 (OMIM: 611320) PREDICTED: interferon ( 129) 243 61.9 3.3e-10 XP_011534709 (OMIM: 611320) PREDICTED: interferon ( 103) 241 61.4 3.8e-10 XP_011534708 (OMIM: 611320) PREDICTED: interferon ( 103) 241 61.4 3.8e-10 XP_016876451 (OMIM: 611320) PREDICTED: interferon ( 113) 237 60.5 7.6e-10 NP_001275885 (OMIM: 600009) interferon alpha-induc ( 122) 237 60.5 8.1e-10 NP_001275881 (OMIM: 600009) interferon alpha-induc ( 122) 237 60.5 8.1e-10 NP_001123552 (OMIM: 600009) interferon alpha-induc ( 122) 237 60.5 8.1e-10 NP_001275883 (OMIM: 600009) interferon alpha-induc ( 119) 231 59.2 2e-09 NP_001275924 (OMIM: 600009) interferon alpha-induc ( 119) 231 59.2 2e-09 NP_001275887 (OMIM: 600009) interferon alpha-induc ( 119) 231 59.2 2e-09 NP_001275886 (OMIM: 600009) interferon alpha-induc ( 119) 231 59.2 2e-09 NP_005523 (OMIM: 600009) interferon alpha-inducibl ( 119) 231 59.2 2e-09 NP_001275889 (OMIM: 600009) interferon alpha-induc ( 74) 217 55.9 1.2e-08 NP_001275888 (OMIM: 600009) interferon alpha-induc ( 79) 217 55.9 1.3e-08 XP_016876452 (OMIM: 611320) PREDICTED: interferon ( 112) 206 53.6 8.8e-08 >>NP_002029 (OMIM: 147572) interferon alpha-inducible pr (130 aa) initn: 840 init1: 840 opt: 840 Z-score: 1018.9 bits: 194.1 E(85289): 5.2e-50 Smith-Waterman score: 840; 100.0% identity (100.0% similar) in 130 aa overlap (1-130:1-130) 10 20 30 40 50 60 pF1KB6 MRQKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MRQKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATH 70 80 90 100 110 120 130 pF1KB6 KYLDSEEDEE :::::::::: NP_002 KYLDSEEDEE 130 >>NP_075010 (OMIM: 147572) interferon alpha-inducible pr (134 aa) initn: 700 init1: 700 opt: 822 Z-score: 997.1 bits: 190.2 E(85289): 8.4e-49 Smith-Waterman score: 822; 97.0% identity (97.0% similar) in 134 aa overlap (1-130:1-134) 10 20 30 40 50 pF1KB6 MRQKAVSLFLCYLLLFTCSGVEAG----KKKCSESSDSGSGFWKALTFMAVGGGLAVAGL :::::::::::::::::::::::: :::::::::::::::::::::::::::::::: NP_075 MRQKAVSLFLCYLLLFTCSGVEAGENAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 PALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_075 PALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMG 70 80 90 100 110 120 120 130 pF1KB6 YATHKYLDSEEDEE :::::::::::::: NP_075 YATHKYLDSEEDEE 130 >>NP_075011 (OMIM: 147572) interferon alpha-inducible pr (138 aa) initn: 702 init1: 702 opt: 814 Z-score: 987.4 bits: 188.4 E(85289): 2.9e-48 Smith-Waterman score: 814; 94.2% identity (94.2% similar) in 138 aa overlap (1-130:1-138) 10 20 30 40 50 pF1KB6 MRQKAVSLFLCYLLLFTCSGVEAG--------KKKCSESSDSGSGFWKALTFMAVGGGLA :::::::::::::::::::::::: :::::::::::::::::::::::::::: NP_075 MRQKAVSLFLCYLLLFTCSGVEAGENAGKDAGKKKCSESSDSGSGFWKALTFMAVGGGLA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 VAGLPALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_075 VAGLPALGFTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIG 70 80 90 100 110 120 120 130 pF1KB6 ALMGYATHKYLDSEEDEE :::::::::::::::::: NP_075 ALMGYATHKYLDSEEDEE 130 >>NP_114425 (OMIM: 611319) interferon alpha-inducible pr (130 aa) initn: 326 init1: 207 opt: 268 Z-score: 334.0 bits: 67.4 E(85289): 7.2e-12 Smith-Waterman score: 268; 57.0% identity (86.1% similar) in 79 aa overlap (46-116:9-87) 20 30 40 50 60 70 pF1KB6 FTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLP----ALGFTGAGIAANSV ::::.:::...: :.:::::::::.:. NP_114 MMKRAAAAAVGGALAVGAVPVVLSAMGFTGAGIAASSI 10 20 30 80 90 100 110 120 pF1KB6 AASLMSWSAILNGGGVPAGGLVATLQSLGAGG----SSVVIGNIGALMGYATHKYLDSEE ::..:: .:: ::::: ::.:::::::.::.: :.......:...: NP_114 AAKMMSAAAIANGGGVSAGSLVATLQSVGAAGLSTSSNILLASVGSVLGACLGNSPSSSL 40 50 60 70 80 90 130 pF1KB6 DEE NP_114 PAEPEAKEDEARENVPQGEPPKPPLKSEKHEE 100 110 120 130 >>NP_660292 (OMIM: 611320) interferon alpha-inducible pr (104 aa) initn: 319 init1: 249 opt: 249 Z-score: 312.6 bits: 63.1 E(85289): 1.1e-10 Smith-Waterman score: 249; 49.5% identity (75.3% similar) in 93 aa overlap (33-125:8-100) 10 20 30 40 50 60 pF1KB6 QKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFT ::: . :.. .:. : ....: :.::: NP_660 MGKESGWDSGRAAVAAVVGGVVAVGTVLVALSAMGFT 10 20 30 70 80 90 100 110 120 pF1KB6 GAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATHKY ..::::.:.::..:: .:: ::::: ::.::: :::.::.: ::. ::.. : : . NP_660 SVGIAASSIAAKMMSTAAIANGGGVAAGSLVAILQSVGAAGLSVTSKVIGGFAGTALGAW 40 50 60 70 80 90 130 pF1KB6 LDSEEDEE : : NP_660 LGSPPSS 100 >>XP_011534707 (OMIM: 611320) PREDICTED: interferon alph (104 aa) initn: 319 init1: 249 opt: 249 Z-score: 312.6 bits: 63.1 E(85289): 1.1e-10 Smith-Waterman score: 249; 49.5% identity (75.3% similar) in 93 aa overlap (33-125:8-100) 10 20 30 40 50 60 pF1KB6 QKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFT ::: . :.. .:. : ....: :.::: XP_011 MGKESGWDSGRAAVAAVVGGVVAVGTVLVALSAMGFT 10 20 30 70 80 90 100 110 120 pF1KB6 GAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATHKY ..::::.:.::..:: .:: ::::: ::.::: :::.::.: ::. ::.. : : . XP_011 SVGIAASSIAAKMMSTAAIANGGGVAAGSLVAILQSVGAAGLSVTSKVIGGFAGTALGAW 40 50 60 70 80 90 130 pF1KB6 LDSEEDEE : : XP_011 LGSPPSS 100 >>NP_996832 (OMIM: 611320) interferon alpha-inducible pr (104 aa) initn: 319 init1: 249 opt: 249 Z-score: 312.6 bits: 63.1 E(85289): 1.1e-10 Smith-Waterman score: 249; 49.5% identity (75.3% similar) in 93 aa overlap (33-125:8-100) 10 20 30 40 50 60 pF1KB6 QKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFT ::: . :.. .:. : ....: :.::: NP_996 MGKESGWDSGRAAVAAVVGGVVAVGTVLVALSAMGFT 10 20 30 70 80 90 100 110 120 pF1KB6 GAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATHKY ..::::.:.::..:: .:: ::::: ::.::: :::.::.: ::. ::.. : : . NP_996 SVGIAASSIAAKMMSTAAIANGGGVAAGSLVAILQSVGAAGLSVTSKVIGGFAGTALGAW 40 50 60 70 80 90 130 pF1KB6 LDSEEDEE : : NP_996 LGSPPSS 100 >>XP_016876450 (OMIM: 611320) PREDICTED: interferon alph (124 aa) initn: 319 init1: 249 opt: 249 Z-score: 311.6 bits: 63.2 E(85289): 1.3e-10 Smith-Waterman score: 249; 49.5% identity (75.3% similar) in 93 aa overlap (33-125:28-120) 10 20 30 40 50 60 pF1KB6 QKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALGFT ::: . :.. .:. : ....: :.::: XP_016 MQKVEVQESEWRLTEAKGPTMGKESGWDSGRAAVAAVVGGVVAVGTVLVALSAMGFT 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 GAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATHKY ..::::.:.::..:: .:: ::::: ::.::: :::.::.: ::. ::.. : : . XP_016 SVGIAASSIAAKMMSTAAIANGGGVAAGSLVAILQSVGAAGLSVTSKVIGGFAGTALGAW 60 70 80 90 100 110 130 pF1KB6 LDSEEDEE : : XP_016 LGSPPSS 120 >>XP_005267371 (OMIM: 611320) PREDICTED: interferon alph (129 aa) initn: 280 init1: 216 opt: 243 Z-score: 304.2 bits: 61.9 E(85289): 3.3e-10 Smith-Waterman score: 243; 43.8% identity (71.4% similar) in 105 aa overlap (21-125:21-125) 10 20 30 40 50 60 pF1KB6 MRQKAVSLFLCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGGGLAVAGLPALG : : . . . ..: . :.. .:. : ....: :.: XP_005 MFLPALRAQHNSGGPGMLCPVLQGAQPQGWAEETGRAAVAAVVGGVVAVGTVLVALSAMG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FTGAGIAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATH ::..::::.:.::..:: .:: ::::: ::.::: :::.::.: ::. ::.. : : XP_005 FTSVGIAASSIAAKMMSTAAIANGGGVAAGSLVAILQSVGAAGLSVTSKVIGGFAGTALG 70 80 90 100 110 120 130 pF1KB6 KYLDSEEDEE .: : XP_005 AWLGSPPSS >>XP_011534709 (OMIM: 611320) PREDICTED: interferon alph (103 aa) initn: 280 init1: 216 opt: 241 Z-score: 303.0 bits: 61.4 E(85289): 3.8e-10 Smith-Waterman score: 241; 50.0% identity (74.4% similar) in 90 aa overlap (40-125:10-99) 10 20 30 40 50 60 pF1KB6 LCYLLLFTCSGVEAGKKKCSESSDSGSGFWKALTFMAVGG----GLAVAGLPALGFTGAG .: . .::: : ....: :.:::..: XP_011 MVRLDISEGRAAVAAVVGGVVAVGTVLVALSAMGFTSVG 10 20 30 70 80 90 100 110 120 pF1KB6 IAANSVAASLMSWSAILNGGGVPAGGLVATLQSLGAGGSSVVIGNIGALMGYATHKYLDS :::.:.::..:: .:: ::::: ::.::: :::.::.: ::. ::.. : : .: : XP_011 IAASSIAAKMMSTAAIANGGGVAAGSLVAILQSVGAAGLSVTSKVIGGFAGTALGAWLGS 40 50 60 70 80 90 130 pF1KB6 EEDEE XP_011 PPSS 100 130 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:41:06 2016 done: Fri Nov 4 23:41:06 2016 Total Scan time: 4.440 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]