FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6737, 97 aa 1>>>pF1KB6737 97 - 97 aa - 97 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7133+/-0.000251; mu= 12.4477+/- 0.016 mean_var=55.9678+/-10.736, 0's: 0 Z-trim(121.5): 67 B-trim: 364 in 1/56 Lambda= 0.171437 statistics sampled from 38117 (38190) to 38117 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.448), width: 16 Scan time: 4.500 The best scores are: opt bits E(85289) NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 658 169.5 7.5e-43 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 462 121.1 3e-28 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 456 119.6 8.3e-28 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 449 117.8 2.8e-27 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 406 107.2 4.4e-24 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 240 66.1 9.5e-12 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 238 65.6 1.3e-11 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 236 65.1 1.9e-11 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 231 63.9 4.5e-11 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 231 63.9 4.5e-11 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 224 62.2 1.8e-10 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 224 62.2 1.8e-10 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 224 62.2 1.8e-10 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 218 60.7 4.1e-10 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 212 59.2 1.2e-09 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 206 57.8 4.4e-09 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 206 57.8 4.6e-09 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 198 55.7 1.2e-08 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 197 55.5 1.5e-08 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 197 55.5 1.5e-08 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 197 55.6 2.2e-08 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 192 54.3 4.1e-08 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 173 49.5 9e-07 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 172 49.4 1.4e-06 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 172 49.4 1.4e-06 XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 171 49.1 1.5e-06 NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 171 49.1 1.5e-06 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 169 48.6 1.9e-06 NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 169 48.6 2.2e-06 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 167 48.2 3.6e-06 NP_002987 (OMIM: 601880) fractalkine isoform 1 pre ( 397) 172 49.7 3.6e-06 NP_001265665 (OMIM: 187011) C-C motif chemokine 5 ( 154) 167 48.2 3.9e-06 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 163 47.1 5.2e-06 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 163 47.1 5.2e-06 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 161 46.6 7.3e-06 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 161 46.7 9.1e-06 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 161 46.7 9.1e-06 XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 158 45.9 1.4e-05 NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 158 45.9 1.4e-05 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 149 43.6 5.8e-05 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 150 43.9 5.9e-05 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 148 43.4 7.3e-05 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 148 43.4 7.9e-05 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 144 42.4 0.00015 NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 141 41.5 0.00017 NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 141 41.5 0.00017 NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 141 41.6 0.00021 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 137 40.7 0.00047 NP_004582 (OMIM: 601960) C-C motif chemokine 20 is ( 96) 134 39.9 0.00076 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 134 39.9 0.00078 >>NP_002977 (OMIM: 600807,601156,609423) eotaxin precurs (97 aa) initn: 658 init1: 658 opt: 658 Z-score: 890.3 bits: 169.5 E(85289): 7.5e-43 Smith-Waterman score: 658; 100.0% identity (100.0% similar) in 97 aa overlap (1-97:1-97) 10 20 30 40 50 60 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQK 10 20 30 40 50 60 70 80 90 pF1KB6 AVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP ::::::::::::::::::::::::::::::::::::: NP_002 AVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP 70 80 90 >>NP_002973 (OMIM: 158105,182940,607948,609423) C-C moti (99 aa) initn: 475 init1: 358 opt: 462 Z-score: 628.2 bits: 121.1 E(85289): 3e-28 Smith-Waterman score: 462; 70.4% identity (88.8% similar) in 98 aa overlap (1-96:1-98) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGPASV--PTTCCFNLANRKIPLQRLESYRRITSGKCP :::::::: ::::::.: ::::: : .. :.:::.:..:::: .::: :::::::.::: NP_002 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP 10 20 30 40 50 60 60 70 80 90 pF1KB6 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP ..:::::: .::.::::::.::::::: .::... ::: NP_002 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT 70 80 90 >>NP_005614 (OMIM: 602283) C-C motif chemokine 8 precurs (99 aa) initn: 349 init1: 349 opt: 456 Z-score: 620.2 bits: 119.6 E(85289): 8.3e-28 Smith-Waterman score: 456; 68.7% identity (86.9% similar) in 99 aa overlap (1-97:1-99) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGP--ASVPTTCCFNLANRKIPLQRLESYRRITSGKCP :::::::: :::.::.::::::: : .:.: :::::. :::::.:::::: :::. .:: NP_005 MKVSAALLCLLLMAATFSPQGLAQPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCP 10 20 30 40 50 60 60 70 80 90 pF1KB6 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP ..::::::: .:..:::::..::.::::.::: . :: NP_005 KEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP 70 80 90 >>NP_006264 (OMIM: 158106) C-C motif chemokine 7 precurs (99 aa) initn: 469 init1: 342 opt: 449 Z-score: 610.8 bits: 117.8 E(85289): 2.8e-27 Smith-Waterman score: 449; 69.4% identity (85.7% similar) in 98 aa overlap (1-96:1-98) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGPASV--PTTCCFNLANRKIPLQRLESYRRITSGKCP ::.::::: ::: :::::::::: :... ::::. . :.::: :::::::: ::..:: NP_006 MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCP 10 20 30 40 50 60 60 70 80 90 pF1KB6 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP ..:::::::: :.::::: .::::: ::.::.:. ::: NP_006 REAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL 70 80 90 >>NP_005399 (OMIM: 601391) C-C motif chemokine 13 precur (98 aa) initn: 411 init1: 214 opt: 406 Z-score: 553.4 bits: 107.2 E(85289): 4.4e-24 Smith-Waterman score: 406; 64.3% identity (87.8% similar) in 98 aa overlap (1-96:1-97) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGPAS--VPTTCCFNLANRKIPLQRLESYRRITSGKCP :::::.:: :::..:::.::::: : . ::.::::.....:: ::::.:: ::...:: NP_005 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYV-ITTSRCP 10 20 30 40 50 60 70 80 90 pF1KB6 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP ::::::.:::.:.::::::.::::. ::.: .:. : : NP_005 QKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT 60 70 80 90 >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 245 init1: 139 opt: 240 Z-score: 331.9 bits: 66.1 E(85289): 9.5e-12 Smith-Waterman score: 240; 40.7% identity (75.8% similar) in 91 aa overlap (1-89:1-90) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGP--ASVPTTCCFNLANRKIPLQRLESYRRITSGKCP ::. ...: ::...::: .:..: .. ::.:::. . ::.: . . .: . ::. : NP_002 MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYE-TSSLCS 10 20 30 40 50 60 70 80 90 pF1KB6 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP : ::.:.:: .:..::::...:::. . :. NP_002 QPAVVFQTKRSKQVCADPSESWVQEYVYDLELN 60 70 80 90 >>NP_002976 (OMIM: 187011) C-C motif chemokine 5 isoform (91 aa) initn: 252 init1: 183 opt: 238 Z-score: 329.3 bits: 65.6 E(85289): 1.3e-11 Smith-Waterman score: 238; 43.3% identity (68.9% similar) in 90 aa overlap (1-89:1-89) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGPASVPTT-CCFNLANRKIPLQRLESYRRITSGKCPQ :::::: : ..:::.:. . :.: : :: ::: : .: ... : ::::: . NP_002 MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFY-TSGKCSN 10 20 30 40 50 60 70 80 90 pF1KB6 KAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP ::.: :. ...::.:.::::.. .. :. NP_002 PAVVFVTRKNRQVCANPEKKWVREYINSLEMS 60 70 80 90 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 236 init1: 133 opt: 236 Z-score: 326.6 bits: 65.1 E(85289): 1.9e-11 Smith-Waterman score: 236; 40.7% identity (75.8% similar) in 91 aa overlap (1-89:1-90) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGP--ASVPTTCCFNLANRKIPLQRLESYRRITSGKCP ::. ...: ::...::: .:..: .. ::.:::. . ::.: . . .: . ::. : NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYE-TSSLCS 10 20 30 40 50 60 70 80 90 pF1KB6 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP : ::.:.:: .:..::::...:::. . :. NP_996 QPAVVFQTKRGKQVCADPSESWVQEYVYDLELN 60 70 80 90 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 186 init1: 121 opt: 231 Z-score: 319.8 bits: 63.9 E(85289): 4.5e-11 Smith-Waterman score: 231; 40.7% identity (75.8% similar) in 91 aa overlap (1-89:1-90) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGP--ASVPTTCCFNLANRKIPLQRLESYRRITSGKCP :.::.: : .:: . :. : :..: :..::.:::. ..:.:: . . .: . ::..: NP_001 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFE-TSSQCS 10 20 30 40 50 60 70 80 90 pF1KB6 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP . .::: :: ....::::...::: .. :. NP_001 KPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 186 init1: 121 opt: 231 Z-score: 319.8 bits: 63.9 E(85289): 4.5e-11 Smith-Waterman score: 231; 40.7% identity (75.8% similar) in 91 aa overlap (1-89:1-90) 10 20 30 40 50 pF1KB6 MKVSAALLWLLLIAAAFSPQGLAGP--ASVPTTCCFNLANRKIPLQRLESYRRITSGKCP :.::.: : .:: . :. : :..: :..::.:::. ..:.:: . . .: . ::..: NP_066 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFE-TSSQCS 10 20 30 40 50 60 70 80 90 pF1KB6 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP . .::: :: ....::::...::: .. :. NP_066 KPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 97 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:42:34 2016 done: Fri Nov 4 23:42:35 2016 Total Scan time: 4.500 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]