FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6739, 98 aa 1>>>pF1KB6739 98 - 98 aa - 98 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6630+/-0.000284; mu= 12.8859+/- 0.018 mean_var=59.2022+/-11.447, 0's: 0 Z-trim(118.7): 34 B-trim: 0 in 0/54 Lambda= 0.166688 statistics sampled from 31804 (31838) to 31804 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.373), width: 16 Scan time: 3.990 The best scores are: opt bits E(85289) NP_001556 (OMIM: 147310) C-X-C motif chemokine 10 ( 98) 640 161.2 2.5e-40 NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 p ( 125) 234 63.6 7.5e-11 NP_005400 (OMIM: 604852) C-X-C motif chemokine 11 ( 94) 194 53.9 4.7e-08 NP_001289052 (OMIM: 604852) C-X-C motif chemokine ( 106) 190 53.0 1e-07 NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 p ( 114) 186 52.0 2.1e-07 XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 167 47.4 4.8e-06 NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 167 47.4 4.8e-06 NP_001502 (OMIM: 155730) growth-regulated alpha pr ( 107) 161 46.0 1.3e-05 NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 p ( 107) 160 45.7 1.5e-05 NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 p ( 114) 159 45.5 1.9e-05 NP_002695 (OMIM: 121010) platelet basic protein pr ( 128) 158 45.3 2.4e-05 NP_002610 (OMIM: 173460) platelet factor 4 precurs ( 101) 150 43.3 7.7e-05 XP_005265753 (OMIM: 173460) PREDICTED: platelet fa ( 110) 150 43.4 8.2e-05 NP_002611 (OMIM: 173461) platelet factor 4 variant ( 104) 148 42.9 0.00011 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 141 41.2 0.00034 NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 p ( 107) 135 39.7 0.00098 NP_001029058 (OMIM: 600835,609423) stromal cell-de ( 119) 131 38.8 0.0021 NP_000600 (OMIM: 600835,609423) stromal cell-deriv ( 93) 128 38.0 0.0028 NP_954637 (OMIM: 600835,609423) stromal cell-deriv ( 89) 127 37.8 0.0032 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 123 36.8 0.0068 >>NP_001556 (OMIM: 147310) C-X-C motif chemokine 10 prec (98 aa) initn: 640 init1: 640 opt: 640 Z-score: 844.9 bits: 161.2 E(85289): 2.5e-40 Smith-Waterman score: 640; 100.0% identity (100.0% similar) in 98 aa overlap (1-98:1-98) 10 20 30 40 50 60 pF1KB6 MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRV 10 20 30 40 50 60 70 80 90 pF1KB6 EIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP :::::::::::::::::::::::::::::::::::::: NP_001 EIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP 70 80 90 >>NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 precu (125 aa) initn: 234 init1: 136 opt: 234 Z-score: 315.8 bits: 63.6 E(85289): 7.5e-11 Smith-Waterman score: 234; 38.1% identity (72.2% similar) in 97 aa overlap (1-96:1-96) 10 20 30 40 50 pF1KB6 MNQTAIL-ICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPR :.....: . .:.:.: :.::.:. : ::.::: .. .. .::. :. . : : . NP_002 MKKSGVLFLLGIILLVLIGVQGTPVVRKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEK 10 20 30 40 50 60 60 70 80 90 pF1KB6 VEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP .:::::.:. : . ::::.: .:.:.: :. :.. NP_002 IEIIATLKN-GVQTCLNPDSADVKELIKKWEKQVSQKKKQKNGKKHQKKKVLKVRKSQRS 70 80 90 100 110 NP_002 RQKKTT 120 >>NP_005400 (OMIM: 604852) C-X-C motif chemokine 11 isof (94 aa) initn: 196 init1: 182 opt: 194 Z-score: 265.5 bits: 53.9 E(85289): 4.7e-08 Smith-Waterman score: 194; 31.5% identity (64.1% similar) in 92 aa overlap (1-92:1-92) 10 20 30 40 50 60 pF1KB6 MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRV :. .. : ..: . .:: :. . :: ::. . . :. ..:: :. :. : .. NP_005 MSVKGMAIALAVILCATVVQGFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKI 10 20 30 40 50 60 70 80 90 pF1KB6 EIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP :.: :.:.. .:::::.:: . ..: : .. NP_005 EVIITLKENKGQRCLNPKSKQARLIIKKVERKNF 70 80 90 >>NP_001289052 (OMIM: 604852) C-X-C motif chemokine 11 i (106 aa) initn: 189 init1: 175 opt: 190 Z-score: 259.6 bits: 53.0 E(85289): 1e-07 Smith-Waterman score: 190; 33.3% identity (63.4% similar) in 93 aa overlap (1-93:1-91) 10 20 30 40 50 60 pF1KB6 MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRV :. .. : ..: . .:: :. . :: ::. . . :. ..:: :. :. : .. NP_001 MSVKGMAIALAVILCATVVQGFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKI 10 20 30 40 50 60 70 80 90 pF1KB6 EIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP :.: :.:.. .:::::.:: . ..: ::: NP_001 EVIITLKENKGQRCLNPKSKQARLIIKL--KERIFKNIKTYEVLEKSI 70 80 90 100 >>NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 precu (114 aa) initn: 169 init1: 103 opt: 186 Z-score: 254.0 bits: 52.0 E(85289): 2.1e-07 Smith-Waterman score: 186; 31.2% identity (70.8% similar) in 96 aa overlap (7-97:21-114) 10 20 30 40 pF1KB6 MNQTAILICCLIFLTLSG--IQGVPLSRTV---RCTCISISNQPVN :. :..:: : .. :.: .. ::::. .. . :: NP_002 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLR-VN 10 20 30 40 50 50 60 70 80 90 pF1KB6 PRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP :... ::...::. : .::..:..:. :.. ::.::. .:.... . .:.. NP_002 PKTIGKLQVFPAGPQCSKVEVVASLKN-GKQVCLDPEAPFLKKVIQKILDSGNKKN 60 70 80 90 100 110 >>XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif che (109 aa) initn: 128 init1: 102 opt: 167 Z-score: 229.5 bits: 47.4 E(85289): 4.8e-06 Smith-Waterman score: 167; 29.8% identity (64.9% similar) in 94 aa overlap (7-98:8-100) 10 20 30 40 50 pF1KB6 MNQTAILICCLIFLTLSGIQGV--PLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFC :. :. .:: .::: ..:: :.. :. . : .....:.: .. : XP_006 MKFISTSLLLMLLVSSLSPVQGVLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGC 10 20 30 40 50 60 60 70 80 90 pF1KB6 PRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP :: :::. ::. :..:... :. ..... :. :. : XP_006 PRKEIIV-WKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP 70 80 90 100 >>NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 prec (109 aa) initn: 128 init1: 102 opt: 167 Z-score: 229.5 bits: 47.4 E(85289): 4.8e-06 Smith-Waterman score: 167; 29.8% identity (64.9% similar) in 94 aa overlap (7-98:8-100) 10 20 30 40 50 pF1KB6 MNQTAILICCLIFLTLSGIQGV--PLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFC :. :. .:: .::: ..:: :.. :. . : .....:.: .. : NP_006 MKFISTSLLLMLLVSSLSPVQGVLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGC 10 20 30 40 50 60 60 70 80 90 pF1KB6 PRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP :: :::. ::. :..:... :. ..... :. :. : NP_006 PRKEIIV-WKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP 70 80 90 100 >>NP_001502 (OMIM: 155730) growth-regulated alpha protei (107 aa) initn: 87 init1: 52 opt: 161 Z-score: 221.9 bits: 46.0 E(85289): 1.3e-05 Smith-Waterman score: 161; 28.7% identity (71.3% similar) in 87 aa overlap (11-94:22-106) 10 20 30 40 pF1KB6 MNQTAILICCLIFLTLSG--IQGVPLSRTVRCTCISISNQPVNPRSLEK :..:. .: :. .. .:: :.. . : ..:..... NP_001 MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQ-TLQGIHPKNIQS 10 20 30 40 50 50 60 70 80 90 pF1KB6 LEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLL-KAVSKERSKRSP ... . : ..:.:::.:. :.: :::: : .:... : .....: NP_001 VNVKSPGPHCAQTEVIATLKN-GRKACLNPASPIVKKIIEKMLNSDKSN 60 70 80 90 100 >>NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 precu (107 aa) initn: 100 init1: 55 opt: 160 Z-score: 220.6 bits: 45.7 E(85289): 1.5e-05 Smith-Waterman score: 160; 31.0% identity (71.8% similar) in 71 aa overlap (21-91:34-102) 10 20 30 40 50 pF1KB6 MNQTAILICCLIFLTLSGIQGVPLSRTVRCTCISISNQPVNPRSLEKLEI :.::. .:: :.. . : .. ........ NP_002 ATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQ-TLQGIHLKNIQSVKV 10 20 30 40 50 60 60 70 80 90 pF1KB6 IPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP . : ..:.:::.:. :.: :::: : .:.... . : NP_002 KSPGPHCAQTEVIATLKN-GQKACLNPASPMVKKIIEKMLKNGKSN 70 80 90 100 >>NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 precu (114 aa) initn: 71 init1: 49 opt: 159 Z-score: 218.9 bits: 45.5 E(85289): 1.9e-05 Smith-Waterman score: 159; 27.5% identity (64.8% similar) in 91 aa overlap (8-89:18-106) 10 20 30 40 pF1KB6 MNQTAILICCLIFLTLSGIQGVPLS---------RTVRCTCISISNQPVN .: :. : : : :.. : .::.:.. ..: :. NP_002 MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIASAGPAAAVLRELRCVCLQ-TTQGVH 10 20 30 40 50 50 60 70 80 90 pF1KB6 PRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP :. . .:... . : .::..:..:. :.. ::.::. .:.... . NP_002 PKMISNLQVFAIGPQCSKVEVVASLKN-GKEICLDPEAPFLKKVIQKILDGGNKEN 60 70 80 90 100 110 98 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:54:54 2016 done: Sat Nov 5 07:54:55 2016 Total Scan time: 3.990 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]