FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6741, 98 aa 1>>>pF1KB6741 98 - 98 aa - 98 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8262+/-0.0003; mu= 11.3340+/- 0.019 mean_var=53.7689+/-10.722, 0's: 0 Z-trim(118.0): 70 B-trim: 508 in 1/49 Lambda= 0.174908 statistics sampled from 30536 (30606) to 30536 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.359), width: 16 Scan time: 4.140 The best scores are: opt bits E(85289) NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 652 171.6 1.8e-43 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 449 120.4 4.7e-28 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 431 115.9 1.1e-26 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 422 113.6 5.3e-26 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 406 109.5 8.6e-25 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 272 75.7 1.2e-14 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 272 75.7 1.2e-14 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 270 75.2 1.8e-14 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 265 74.0 4.2e-14 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 240 67.6 3.3e-12 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 236 66.6 6.8e-12 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 233 65.9 1.1e-11 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 222 63.2 9.7e-11 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 222 63.2 9.7e-11 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 222 63.2 9.7e-11 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 218 62.1 1.8e-10 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 216 61.6 2.3e-10 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 216 61.6 2.3e-10 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 215 61.3 2.6e-10 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 216 61.7 3.3e-10 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 193 55.8 1.3e-08 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 190 55.1 2.6e-08 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 190 55.1 2.6e-08 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 188 54.5 2.9e-08 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 173 50.7 4.2e-07 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 173 50.8 5.2e-07 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 173 50.8 5.2e-07 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 171 50.2 5.9e-07 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 171 50.2 5.9e-07 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 168 49.5 1.2e-06 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 167 49.3 1.6e-06 XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 166 49.0 1.7e-06 NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 166 49.0 1.7e-06 NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 166 49.0 1.7e-06 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 164 48.5 2.2e-06 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 165 48.8 2.3e-06 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 165 48.8 2.4e-06 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 163 48.3 2.9e-06 NP_002987 (OMIM: 601880) fractalkine isoform 1 pre ( 397) 165 49.0 5.7e-06 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 155 46.2 9.9e-06 NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 153 45.6 1e-05 NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 153 45.6 1e-05 NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 153 45.7 1.3e-05 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 153 45.7 1.5e-05 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 144 43.4 6.9e-05 NP_001265665 (OMIM: 187011) C-C motif chemokine 5 ( 154) 145 43.8 8.5e-05 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 142 42.9 9.9e-05 NP_000600 (OMIM: 600835,609423) stromal cell-deriv ( 93) 133 40.6 0.00045 NP_954637 (OMIM: 600835,609423) stromal cell-deriv ( 89) 131 40.1 0.00062 NP_001029058 (OMIM: 600835,609423) stromal cell-de ( 119) 131 40.2 0.00079 >>NP_005399 (OMIM: 601391) C-C motif chemokine 13 precur (98 aa) initn: 652 init1: 652 opt: 652 Z-score: 901.5 bits: 171.6 E(85289): 1.8e-43 Smith-Waterman score: 652; 100.0% identity (100.0% similar) in 98 aa overlap (1-98:1-98) 10 20 30 40 50 60 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQ 10 20 30 40 50 60 70 80 90 pF1KB6 KAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT :::::::::::::::::::::::::::::::::::::: NP_005 KAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT 70 80 90 >>NP_002973 (OMIM: 158105,182940,607948,609423) C-C moti (99 aa) initn: 267 init1: 259 opt: 449 Z-score: 624.6 bits: 120.4 E(85289): 4.7e-28 Smith-Waterman score: 449; 64.6% identity (89.9% similar) in 99 aa overlap (1-98:1-99) 10 20 30 40 50 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYV-ITTSRCP :::::.::::::..:.: :::::::::.:.: :::..:...:::.::: :: ::.:.:: NP_002 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP 10 20 30 40 50 60 60 70 80 90 pF1KB6 QKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT ..::::.: ..::::::::.::::. : :: ....: :: NP_002 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT 70 80 90 >>NP_005614 (OMIM: 602283) C-C motif chemokine 8 precurs (99 aa) initn: 429 init1: 245 opt: 431 Z-score: 600.1 bits: 115.9 E(85289): 1.1e-26 Smith-Waterman score: 431; 62.2% identity (88.8% similar) in 98 aa overlap (1-97:1-98) 10 20 30 40 50 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYV-ITTSRCP :::::.:::::::.:.:.::::::::....: ::::. ..:: .:::.::. ::. .:: NP_005 MKVSAALLCLLLMAATFSPQGLAQPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCP 10 20 30 40 50 60 60 70 80 90 pF1KB6 QKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT ..::::.:: :::.::::::.::.. :::: . ..:: NP_005 KEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP 70 80 90 >>NP_006264 (OMIM: 158106) C-C motif chemokine 7 precurs (99 aa) initn: 420 init1: 231 opt: 422 Z-score: 587.8 bits: 113.6 E(85289): 5.3e-26 Smith-Waterman score: 422; 64.3% identity (85.7% similar) in 98 aa overlap (1-97:1-98) 10 20 30 40 50 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTS-RCP ::.::.:::::: .:::.::::::: ..:. .:::. : .::: :::.:: ::: .:: NP_006 MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCP 10 20 30 40 50 60 60 70 80 90 pF1KB6 QKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT ..::::.::: ::::::: .::::..:::: .:..: : NP_006 REAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL 70 80 90 >>NP_002977 (OMIM: 600807,601156,609423) eotaxin precurs (97 aa) initn: 411 init1: 214 opt: 406 Z-score: 566.1 bits: 109.5 E(85289): 8.6e-25 Smith-Waterman score: 406; 64.3% identity (87.8% similar) in 98 aa overlap (1-97:1-96) 10 20 30 40 50 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYV-ITTSRCP :::::.:: :::..:::.::::: : . ::.::::.....:: ::::.:: ::...:: NP_002 MKVSAALLWLLLIAAAFSPQGLAGPAS--VPTTCCFNLANRKIPLQRLESYRRITSGKCP 10 20 30 40 50 60 70 80 90 pF1KB6 QKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT ::::::.:::.:.::::::.::::. ::.: .:. : : NP_002 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP 60 70 80 90 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 285 init1: 263 opt: 272 Z-score: 383.6 bits: 75.7 E(85289): 1.2e-14 Smith-Waterman score: 272; 42.7% identity (76.4% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQ :.::.. : .:: : :. : :. : : ..:..:::...:..: . . .: :.:.: . NP_066 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 70 80 90 pF1KB6 KAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT .::: :: :...::::.:.:::.:.. : NP_066 PSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 285 init1: 263 opt: 272 Z-score: 383.6 bits: 75.7 E(85289): 1.2e-14 Smith-Waterman score: 272; 42.7% identity (76.4% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQ :.::.. : .:: : :. : :. : : ..:..:::...:..: . . .: :.:.: . NP_001 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 60 70 80 90 pF1KB6 KAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT .::: :: :...::::.:.:::.:.. : NP_001 PSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 70 80 90 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 287 init1: 270 opt: 270 Z-score: 381.0 bits: 75.2 E(85289): 1.8e-14 Smith-Waterman score: 270; 41.6% identity (76.4% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQ ::. ...: ::...::: .:. : . . :..:::.....:. . . .: :.: : : NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 70 80 90 pF1KB6 KAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT ::.:.:: ::..::::.:.:::.:. : NP_996 PAVVFQTKRGKQVCADPSESWVQEYVYDLELN 70 80 90 >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 289 init1: 265 opt: 265 Z-score: 374.2 bits: 74.0 E(85289): 4.2e-14 Smith-Waterman score: 265; 40.4% identity (76.4% similar) in 89 aa overlap (1-89:1-89) 10 20 30 40 50 60 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQ ::. ...: ::...::: .:. : . . :..:::.....:. . . .: :.: : : NP_002 MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQ 10 20 30 40 50 60 70 80 90 pF1KB6 KAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT ::.:.:: .:..::::.:.:::.:. : NP_002 PAVVFQTKRSKQVCADPSESWVQEYVYDLELN 70 80 90 >>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa) initn: 244 init1: 196 opt: 240 Z-score: 340.1 bits: 67.6 E(85289): 3.3e-12 Smith-Waterman score: 240; 39.3% identity (75.3% similar) in 89 aa overlap (1-89:1-88) 10 20 30 40 50 60 pF1KB6 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQ :.::.. : .:: : :. : .. : ..:..:::...:..: . . .: :.:.: . NP_002 MQVSTAALAVLLCTMALCNQ-FSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSK 10 20 30 40 50 70 80 90 pF1KB6 KAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT .::: :: ....::::.:.:::.:.. : NP_002 PGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 98 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:43:40 2016 done: Fri Nov 4 23:43:41 2016 Total Scan time: 4.140 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]