FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6742, 142 aa 1>>>pF1KB6742 142 - 142 aa - 142 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8200+/-0.000285; mu= 13.8625+/- 0.018 mean_var=58.5629+/-11.855, 0's: 0 Z-trim(118.3): 53 B-trim: 53 in 1/52 Lambda= 0.167596 statistics sampled from 31054 (31114) to 31054 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.365), width: 16 Scan time: 4.490 The best scores are: opt bits E(85289) NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 950 237.2 7e-63 NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-tr ( 142) 950 237.2 7e-63 NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans ( 142) 950 237.2 7e-63 XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-pr ( 142) 950 237.2 7e-63 NP_060416 (OMIM: 614505,614557) peptidyl-prolyl ci ( 211) 346 91.2 8.8e-19 NP_001128684 (OMIM: 607062) peptidyl-prolyl cis-tr ( 221) 334 88.3 6.8e-18 XP_011523402 (OMIM: 259450,607063,610968) PREDICTE ( 510) 335 88.8 1.1e-17 NP_068758 (OMIM: 259450,607063,610968) peptidyl-pr ( 582) 335 88.9 1.3e-17 XP_011523401 (OMIM: 259450,607063,610968) PREDICTE ( 601) 335 88.9 1.3e-17 NP_851939 (OMIM: 607062) peptidyl-prolyl cis-trans ( 222) 329 87.1 1.6e-17 NP_057678 (OMIM: 610571) peptidyl-prolyl cis-trans ( 201) 324 85.9 3.4e-17 NP_001271272 (OMIM: 616257) peptidyl-prolyl cis-tr ( 338) 324 86.0 5.1e-17 NP_009201 (OMIM: 616257) peptidyl-prolyl cis-trans ( 570) 324 86.2 7.8e-17 NP_001271270 (OMIM: 616257) peptidyl-prolyl cis-tr ( 623) 324 86.2 8.4e-17 NP_001139249 (OMIM: 602623,608516) peptidyl-prolyl ( 268) 318 84.5 1.2e-16 NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 318 84.7 1.8e-16 NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 318 84.7 1.8e-16 NP_004108 (OMIM: 602623,608516) peptidyl-prolyl ci ( 457) 318 84.7 1.8e-16 NP_000792 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 305 81.1 4.9e-16 NP_463460 (OMIM: 186945) peptidyl-prolyl cis-trans ( 108) 305 81.1 4.9e-16 XP_011534867 (OMIM: 186947) PREDICTED: peptidyl-pr ( 191) 305 81.3 7.8e-16 NP_002004 (OMIM: 186947) peptidyl-prolyl cis-trans ( 224) 305 81.3 8.9e-16 NP_001137254 (OMIM: 610571) peptidyl-prolyl cis-tr ( 146) 302 80.5 1e-15 XP_011513417 (OMIM: 616257) PREDICTED: peptidyl-pr ( 359) 291 78.1 1.4e-14 XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-pr ( 414) 291 78.1 1.5e-14 NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans ( 459) 291 78.1 1.7e-14 NP_004107 (OMIM: 600620) peptidyl-prolyl cis-trans ( 108) 272 73.2 1.2e-13 XP_005246695 (OMIM: 607062) PREDICTED: peptidyl-pr ( 181) 269 72.6 3.1e-13 XP_016876582 (OMIM: 186947) PREDICTED: peptidyl-pr ( 196) 258 69.9 2.1e-12 XP_016876581 (OMIM: 186947) PREDICTED: peptidyl-pr ( 229) 258 70.0 2.4e-12 XP_016859085 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 231 63.2 9.3e-11 XP_016859083 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 231 63.2 9.3e-11 NP_001309893 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 231 63.2 9.3e-11 XP_016859084 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 231 63.2 9.3e-11 XP_016859082 (OMIM: 600620) PREDICTED: peptidyl-pr ( 79) 231 63.2 9.3e-11 NP_001309892 (OMIM: 600620) peptidyl-prolyl cis-tr ( 79) 231 63.2 9.3e-11 XP_016868231 (OMIM: 604839) PREDICTED: inactive pe ( 266) 176 50.2 2.5e-06 XP_006716216 (OMIM: 604839) PREDICTED: inactive pe ( 282) 176 50.2 2.6e-06 XP_016868230 (OMIM: 604839) PREDICTED: inactive pe ( 317) 176 50.2 2.9e-06 NP_001128683 (OMIM: 604839) inactive peptidyl-prol ( 322) 176 50.2 2.9e-06 NP_003593 (OMIM: 604839) inactive peptidyl-prolyl ( 327) 176 50.2 3e-06 NP_001137253 (OMIM: 610571) peptidyl-prolyl cis-tr ( 99) 167 47.7 5.1e-06 NP_473374 (OMIM: 600620) peptidyl-prolyl cis-trans ( 80) 158 45.5 1.9e-05 XP_011531001 (OMIM: 600620) PREDICTED: peptidyl-pr ( 100) 158 45.6 2.3e-05 NP_001295302 (OMIM: 604840) peptidyl-prolyl cis-tr ( 412) 150 44.0 0.00028 XP_011526166 (OMIM: 604840) PREDICTED: peptidyl-pr ( 383) 141 41.8 0.0012 XP_011526165 (OMIM: 604840) PREDICTED: peptidyl-pr ( 413) 141 41.8 0.0013 NP_036313 (OMIM: 604840) peptidyl-prolyl cis-trans ( 413) 141 41.8 0.0013 NP_001268233 (OMIM: 604839) inactive peptidyl-prol ( 297) 129 38.9 0.0072 >>NP_004461 (OMIM: 186946) peptidyl-prolyl cis-trans iso (142 aa) initn: 950 init1: 950 opt: 950 Z-score: 1249.9 bits: 237.2 E(85289): 7e-63 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 70 80 90 100 110 120 130 140 pF1KB6 IPGGATLVFEVELLKIERRTEL :::::::::::::::::::::: NP_004 IPGGATLVFEVELLKIERRTEL 130 140 >>NP_001128680 (OMIM: 186946) peptidyl-prolyl cis-trans (142 aa) initn: 950 init1: 950 opt: 950 Z-score: 1249.9 bits: 237.2 E(85289): 7e-63 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 70 80 90 100 110 120 130 140 pF1KB6 IPGGATLVFEVELLKIERRTEL :::::::::::::::::::::: NP_001 IPGGATLVFEVELLKIERRTEL 130 140 >>NP_476433 (OMIM: 186946) peptidyl-prolyl cis-trans iso (142 aa) initn: 950 init1: 950 opt: 950 Z-score: 1249.9 bits: 237.2 E(85289): 7e-63 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_476 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 70 80 90 100 110 120 130 140 pF1KB6 IPGGATLVFEVELLKIERRTEL :::::::::::::::::::::: NP_476 IPGGATLVFEVELLKIERRTEL 130 140 >>XP_005273905 (OMIM: 186946) PREDICTED: peptidyl-prolyl (142 aa) initn: 950 init1: 950 opt: 950 Z-score: 1249.9 bits: 237.2 E(85289): 7e-63 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142) 10 20 30 40 50 60 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 70 80 90 100 110 120 130 140 pF1KB6 IPGGATLVFEVELLKIERRTEL :::::::::::::::::::::: XP_005 IPGGATLVFEVELLKIERRTEL 130 140 >>NP_060416 (OMIM: 614505,614557) peptidyl-prolyl cis-tr (211 aa) initn: 302 init1: 208 opt: 346 Z-score: 458.2 bits: 91.2 E(85289): 8.8e-19 Smith-Waterman score: 346; 43.9% identity (68.3% similar) in 139 aa overlap (1-136:1-134) 10 20 30 40 50 60 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL ::: : .::.. .... : : . :... : . : :.. ::.. .:: : : NP_060 MRL--FLWNAVLTLFVTSLIGALIPEPEVKIEVLQKPFI--CHRKTKGGDLMLVHYEGYL 10 20 30 40 50 70 80 90 100 110 pF1KB6 E-DGTEFDSSLPQN--QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGA : ::. : :. .: ::. :.:: ...::::::: ::: ::::::.:: ::::..: NP_060 EKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGK 60 70 80 90 100 110 120 130 140 pF1KB6 PPKIPGGATLVFEVELLKIERRTEL ::: .::.:...::.: NP_060 G-KIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVV 120 130 140 150 160 170 >>NP_001128684 (OMIM: 607062) peptidyl-prolyl cis-trans (221 aa) initn: 286 init1: 218 opt: 334 Z-score: 442.2 bits: 88.3 E(85289): 6.8e-18 Smith-Waterman score: 334; 46.6% identity (69.8% similar) in 116 aa overlap (26-138:30-145) 10 20 30 40 50 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHY :. ....: : .: ..: :.:::.:. :: NP_001 MPKTMHFLFRFIVFFYLWGLFTAQRQKKEESTEEVKIEVLHRPENCSKTSKKGDLLNAHY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TGKL-EDGTEFDSSLPQNQ--PFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYG : : .::..: : ::. : : ::.:::::: : .. :: :::::.::: ..:: NP_001 DGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKRKVVIPPSFAYG 70 80 90 100 110 120 120 130 140 pF1KB6 ERGAPPKIPGGATLVFEVELLKIERRTEL ..: ::: :::.::.:: . . NP_001 KEGYEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQLSKAEINLYLQREFEKD 130 140 150 160 170 180 >>XP_011523402 (OMIM: 259450,607063,610968) PREDICTED: p (510 aa) initn: 723 init1: 326 opt: 335 Z-score: 438.2 bits: 88.8 E(85289): 1.1e-17 Smith-Waterman score: 335; 46.2% identity (69.8% similar) in 106 aa overlap (31-136:65-170) 10 20 30 40 50 60 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL .:... : ::: . :: ...::.: : XP_011 RSLIQAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTL 40 50 60 70 80 90 70 80 90 100 110 120 pF1KB6 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK ::: ::.: .. . .:.: .::: :::::::: ::.::..:: :.:::.: XP_011 LDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTV 100 110 120 130 140 150 130 140 pF1KB6 IPGGATLVFEVELLKIERRTEL :: :.:::.: :. . XP_011 IPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDS 160 170 180 190 200 210 >-- initn: 397 init1: 302 opt: 308 Z-score: 403.0 bits: 82.3 E(85289): 1e-15 Smith-Waterman score: 308; 46.2% identity (74.2% similar) in 93 aa overlap (42-134:188-280) 20 30 40 50 60 70 pF1KB6 LSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLP : .. :: ...::.:.: ::: :::: XP_011 QASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYS 160 170 180 190 200 210 80 90 100 110 120 130 pF1KB6 QNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEV .:. . .: : .: : :::: : : ::.:...:: .:.::: :. ::::.:.:.:.: XP_011 RNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNV 220 230 240 250 260 270 140 pF1KB6 ELLKIERRTEL ... XP_011 HVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSGETDAGSHE 280 290 300 310 320 330 >-- initn: 249 init1: 158 opt: 215 Z-score: 281.4 bits: 59.8 E(85289): 6.2e-09 Smith-Waterman score: 227; 39.1% identity (63.5% similar) in 115 aa overlap (42-137:301-414) 20 30 40 50 60 pF1KB6 LSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTE-FDS-- : .. :: ...::. .: :::. : : XP_011 AVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSGE 280 290 300 310 320 330 70 80 90 100 110 pF1KB6 --------SLPQ--------NQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGY : :. . : .::...::.: : :: ::: ::.:.:..: .:.. XP_011 TDAGSHEPSRPHFRGQRHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAH 340 350 360 370 380 390 120 130 140 pF1KB6 GERGAPPKIPGGATLVFEVELLKIERRTEL :: :: .::.:.:.:::::.. : XP_011 GESGARG-VPGSAVLLFEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEE 400 410 420 430 440 >>NP_068758 (OMIM: 259450,607063,610968) peptidyl-prolyl (582 aa) initn: 973 init1: 326 opt: 335 Z-score: 437.4 bits: 88.9 E(85289): 1.3e-17 Smith-Waterman score: 335; 46.2% identity (69.8% similar) in 106 aa overlap (31-136:156-261) 10 20 30 40 50 60 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL .:... : ::: . :: ...::.: : NP_068 GSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTL 130 140 150 160 170 180 70 80 90 100 110 120 pF1KB6 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK ::: ::.: .. . .:.: .::: :::::::: ::.::..:: :.:::.: NP_068 LDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTV 190 200 210 220 230 240 130 140 pF1KB6 IPGGATLVFEVELLKIERRTEL :: :.:::.: :. . NP_068 IPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDS 250 260 270 280 290 300 >-- initn: 397 init1: 302 opt: 308 Z-score: 402.1 bits: 82.3 E(85289): 1.2e-15 Smith-Waterman score: 308; 46.2% identity (74.2% similar) in 93 aa overlap (42-134:279-371) 20 30 40 50 60 70 pF1KB6 LSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLP : .. :: ...::.:.: ::: :::: NP_068 QASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYS 250 260 270 280 290 300 80 90 100 110 120 130 pF1KB6 QNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEV .:. . .: : .: : :::: : : ::.:...:: .:.::: :. ::::.:.:.:.: NP_068 RNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNV 310 320 330 340 350 360 140 pF1KB6 ELLKIERRTEL ... NP_068 HVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEA 370 380 390 400 410 420 >-- initn: 321 init1: 301 opt: 301 Z-score: 393.0 bits: 80.6 E(85289): 3.8e-15 Smith-Waterman score: 301; 45.3% identity (71.6% similar) in 95 aa overlap (42-136:55-149) 20 30 40 50 60 70 pF1KB6 LSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLP :: . . :: ...::.: .::: .:::: NP_068 QAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYD 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB6 QNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEV .: .. .:.:..: : :.::.::: .:.:.:..: .:::: : :: ::: :.: NP_068 RNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDV 90 100 110 120 130 140 140 pF1KB6 ELLKIERRTEL :: . NP_068 VLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTY 150 160 170 180 190 200 >-- initn: 261 init1: 213 opt: 268 Z-score: 349.9 bits: 72.7 E(85289): 9.5e-13 Smith-Waterman score: 268; 43.8% identity (74.0% similar) in 96 aa overlap (42-137:392-486) 20 30 40 50 60 70 pF1KB6 LSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLP : .. :: ...::. .: :::.. .: NP_068 AVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHD 370 380 390 400 410 420 80 90 100 110 120 130 pF1KB6 QNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEV . : .::...::.: : :: ::: ::.:.:..: .:..:: :: .::.:.:.::: NP_068 YGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARG-VPGSAVLLFEV 430 440 450 460 470 480 140 pF1KB6 ELLKIERRTEL ::.. : NP_068 ELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRLMPG 490 500 510 520 530 540 >>XP_011523401 (OMIM: 259450,607063,610968) PREDICTED: p (601 aa) initn: 973 init1: 326 opt: 335 Z-score: 437.2 bits: 88.9 E(85289): 1.3e-17 Smith-Waterman score: 335; 46.2% identity (69.8% similar) in 106 aa overlap (31-136:156-261) 10 20 30 40 50 60 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL .:... : ::: . :: ...::.: : XP_011 GSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTL 130 140 150 160 170 180 70 80 90 100 110 120 pF1KB6 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK ::: ::.: .. . .:.: .::: :::::::: ::.::..:: :.:::.: XP_011 LDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTV 190 200 210 220 230 240 130 140 pF1KB6 IPGGATLVFEVELLKIERRTEL :: :.:::.: :. . XP_011 IPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDS 250 260 270 280 290 300 >-- initn: 397 init1: 302 opt: 308 Z-score: 401.9 bits: 82.3 E(85289): 1.2e-15 Smith-Waterman score: 308; 46.2% identity (74.2% similar) in 93 aa overlap (42-134:279-371) 20 30 40 50 60 70 pF1KB6 LSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLP : .. :: ...::.:.: ::: :::: XP_011 QASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYS 250 260 270 280 290 300 80 90 100 110 120 130 pF1KB6 QNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEV .:. . .: : .: : :::: : : ::.:...:: .:.::: :. ::::.:.:.:.: XP_011 RNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNV 310 320 330 340 350 360 140 pF1KB6 ELLKIERRTEL ... XP_011 HVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSGETDAGSHE 370 380 390 400 410 420 >-- initn: 321 init1: 301 opt: 301 Z-score: 392.8 bits: 80.6 E(85289): 3.9e-15 Smith-Waterman score: 301; 45.3% identity (71.6% similar) in 95 aa overlap (42-136:55-149) 20 30 40 50 60 70 pF1KB6 LSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLP :: . . :: ...::.: .::: .:::: XP_011 QAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYD 30 40 50 60 70 80 80 90 100 110 120 130 pF1KB6 QNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEV .: .. .:.:..: : :.::.::: .:.:.:..: .:::: : :: ::: :.: XP_011 RNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDV 90 100 110 120 130 140 140 pF1KB6 ELLKIERRTEL :: . XP_011 VLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTY 150 160 170 180 190 200 >-- initn: 249 init1: 158 opt: 215 Z-score: 280.4 bits: 59.8 E(85289): 7e-09 Smith-Waterman score: 227; 39.1% identity (63.5% similar) in 115 aa overlap (42-137:392-505) 20 30 40 50 60 pF1KB6 LSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTE-FDS-- : .. :: ...::. .: :::. : : XP_011 AVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSGE 370 380 390 400 410 420 70 80 90 100 110 pF1KB6 --------SLPQ--------NQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGY : :. . : .::...::.: : :: ::: ::.:.:..: .:.. XP_011 TDAGSHEPSRPHFRGQRHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAH 430 440 450 460 470 480 120 130 140 pF1KB6 GERGAPPKIPGGATLVFEVELLKIERRTEL :: :: .::.:.:.:::::.. : XP_011 GESGARG-VPGSAVLLFEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEE 490 500 510 520 530 540 >>NP_851939 (OMIM: 607062) peptidyl-prolyl cis-trans iso (222 aa) initn: 281 init1: 153 opt: 329 Z-score: 435.6 bits: 87.1 E(85289): 1.6e-17 Smith-Waterman score: 329; 47.0% identity (70.1% similar) in 117 aa overlap (26-138:30-146) 10 20 30 40 50 pF1KB6 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHY :. ....: : .: ..: :.:::.:. :: NP_851 MPKTMHFLFRFIVFFYLWGLFTAQRQKKEESTEEVKIEVLHRPENCSKTSKKGDLLNAHY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TGKL-EDGTEFDSSLPQNQ--PFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYG : : .::..: : ::. : : ::.:::::: : .. :: :::::.::: ..:: NP_851 DGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKRKVVIPPSFAYG 70 80 90 100 110 120 120 130 140 pF1KB6 ERG-APPKIPGGATLVFEVELLKIERRTEL ..: : ::: :::.::.:: . . NP_851 KEGYAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQLSKAEINLYLQREFEK 130 140 150 160 170 180 142 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:45:13 2016 done: Fri Nov 4 23:45:14 2016 Total Scan time: 4.490 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]