FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6743, 99 aa 1>>>pF1KB6743 99 - 99 aa - 99 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5162+/-0.000302; mu= 12.9999+/- 0.019 mean_var=53.5314+/-10.388, 0's: 0 Z-trim(117.4): 65 B-trim: 319 in 1/49 Lambda= 0.175295 statistics sampled from 29276 (29341) to 29276 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.344), width: 16 Scan time: 4.120 The best scores are: opt bits E(85289) NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 657 173.2 5.9e-44 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 489 130.8 3.6e-31 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 482 129.0 1.2e-30 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 462 123.9 4e-29 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 449 120.6 4e-28 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 237 67.0 5.3e-12 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 237 67.0 5.3e-12 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 234 66.3 8.8e-12 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 230 65.2 1.8e-11 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 214 61.2 2.9e-10 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 214 61.3 3.6e-10 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 214 61.3 3.6e-10 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 214 61.3 3.6e-10 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 202 58.1 2.3e-09 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 194 56.1 9.7e-09 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 193 56.0 1.6e-08 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 193 56.0 1.7e-08 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 189 54.9 2.4e-08 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 174 51.1 3.7e-07 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 174 51.2 4e-07 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 174 51.2 4e-07 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 168 49.6 9.4e-07 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 168 49.6 9.4e-07 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 165 48.8 1.6e-06 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 161 47.8 3.2e-06 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 161 47.8 3.2e-06 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 161 47.9 4.7e-06 NP_002987 (OMIM: 601880) fractalkine isoform 1 pre ( 397) 165 49.2 5e-06 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 158 47.0 5.3e-06 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 147 44.3 3.8e-05 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 147 44.3 4.1e-05 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 147 44.3 4.6e-05 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 147 44.3 4.7e-05 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 145 43.8 5.5e-05 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 143 43.3 9.2e-05 NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 140 42.4 9.5e-05 NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 140 42.4 9.5e-05 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 143 43.4 0.0001 NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 140 42.5 0.00012 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 140 42.5 0.00014 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 139 42.3 0.00018 NP_001123518 (OMIM: 601960) C-C motif chemokine 20 ( 95) 137 41.7 0.00022 NP_004582 (OMIM: 601960) C-C motif chemokine 20 is ( 96) 137 41.7 0.00022 NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 134 41.0 0.00043 XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 134 41.0 0.00043 NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 134 41.0 0.00043 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 128 39.5 0.0011 NP_001265665 (OMIM: 187011) C-C motif chemokine 5 ( 154) 127 39.3 0.0019 XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 121 37.7 0.0041 NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 121 37.7 0.0041 >>NP_002973 (OMIM: 158105,182940,607948,609423) C-C moti (99 aa) initn: 657 init1: 657 opt: 657 Z-score: 910.2 bits: 173.2 E(85289): 5.9e-44 Smith-Waterman score: 657; 100.0% identity (100.0% similar) in 99 aa overlap (1-99:1-99) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP 10 20 30 40 50 60 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT ::::::::::::::::::::::::::::::::::::::: NP_002 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT 70 80 90 >>NP_006264 (OMIM: 158106) C-C motif chemokine 7 precurs (99 aa) initn: 489 init1: 489 opt: 489 Z-score: 680.5 bits: 130.8 E(85289): 3.6e-31 Smith-Waterman score: 489; 74.5% identity (84.7% similar) in 98 aa overlap (1-98:1-98) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP ::.::::::::: ::.: ::::::: .::. .:::: : :.:: ::: :::: :::.:: NP_006 MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCP 10 20 30 40 50 60 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT .::::::: . ::::::: :::::: : ::::.::::: NP_006 REAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL 70 80 90 >>NP_005614 (OMIM: 602283) C-C motif chemokine 8 precurs (99 aa) initn: 501 init1: 478 opt: 482 Z-score: 671.0 bits: 129.0 E(85289): 1.2e-30 Smith-Waterman score: 482; 69.4% identity (85.7% similar) in 98 aa overlap (1-98:1-98) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP ::::::::::::.:::: ::::::::... :.:::.: :::: .::: :: :::. .:: NP_005 MKVSAALLCLLLMAATFSPQGLAQPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCP 10 20 30 40 50 60 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT :::::::: .::.:::::..::.::: :::. :. : NP_005 KEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP 70 80 90 >>NP_002977 (OMIM: 600807,601156,609423) eotaxin precurs (97 aa) initn: 370 init1: 358 opt: 462 Z-score: 643.8 bits: 123.9 E(85289): 4e-29 Smith-Waterman score: 462; 70.4% identity (88.8% similar) in 98 aa overlap (1-98:1-96) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP :::::::: ::::::.: ::::: : .. :.:::.:..:::: .::: :::::::.::: NP_002 MKVSAALLWLLLIAAAFSPQGLAGPASV--PTTCCFNLANRKIPLQRLESYRRITSGKCP 10 20 30 40 50 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT ..:::::: .::.::::::.::::::: .::... ::: NP_002 QKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP 60 70 80 90 >>NP_005399 (OMIM: 601391) C-C motif chemokine 13 precur (98 aa) initn: 267 init1: 259 opt: 449 Z-score: 625.9 bits: 120.6 E(85289): 4e-28 Smith-Waterman score: 449; 64.6% identity (89.9% similar) in 99 aa overlap (1-99:1-98) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP :::::.::::::..:.: :::::::::.:.: :::..:...:::.::: :: ::.:.:: NP_005 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKSYV-ITTSRCP 10 20 30 40 50 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT ..::::.: ..::::::::.::::. : :: ....: :: NP_005 QKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT 60 70 80 90 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 255 init1: 128 opt: 237 Z-score: 336.5 bits: 67.0 E(85289): 5.3e-12 Smith-Waterman score: 237; 39.6% identity (74.7% similar) in 91 aa overlap (1-91:1-90) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP :.::.: : .:: . .. : :. : : ..:..::...:.:.: . .:.: . :::.: NP_001 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFE-TSSQCS 10 20 30 40 50 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT : .::: : ....::::...::: .. :. NP_001 KPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 255 init1: 128 opt: 237 Z-score: 336.5 bits: 67.0 E(85289): 5.3e-12 Smith-Waterman score: 237; 39.6% identity (74.7% similar) in 91 aa overlap (1-91:1-90) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP :.::.: : .:: . .. : :. : : ..:..::...:.:.: . .:.: . :::.: NP_066 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFE-TSSQCS 10 20 30 40 50 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT : .::: : ....::::...::: .. :. NP_066 KPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 237 init1: 128 opt: 234 Z-score: 332.5 bits: 66.3 E(85289): 8.8e-12 Smith-Waterman score: 234; 36.3% identity (74.7% similar) in 91 aa overlap (1-91:1-90) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP ::. ...: ::...:.: .:. : . . :..::...: ::. . ...: . ::: : NP_002 MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYE-TSSLCS 10 20 30 40 50 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT . ::.:.: .:..::::...:::. . :. NP_002 QPAVVFQTKRSKQVCADPSESWVQEYVYDLELN 60 70 80 90 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 233 init1: 127 opt: 230 Z-score: 327.0 bits: 65.2 E(85289): 1.8e-11 Smith-Waterman score: 230; 36.3% identity (74.7% similar) in 91 aa overlap (1-91:1-90) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP ::. ...: ::...:.: .:. : . . :..::...: ::. . ...: . ::: : NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVDYYE-TSSLCS 10 20 30 40 50 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT . ::.:.: .:..::::...:::. . :. NP_996 QPAVVFQTKRGKQVCADPSESWVQEYVYDLELN 60 70 80 90 >>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa) initn: 208 init1: 128 opt: 214 Z-score: 305.1 bits: 61.2 E(85289): 2.9e-10 Smith-Waterman score: 214; 37.4% identity (73.6% similar) in 91 aa overlap (1-91:1-89) 10 20 30 40 50 60 pF1KB6 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP :.::.: : .:: . .. : .. : ..:..::...:.:.: . .:.: . :::.: NP_002 MQVSTAALAVLLCTMALCNQ-FSASLAADTPTACCFSYTSRQIPQNFIADYFE-TSSQCS 10 20 30 40 50 70 80 90 pF1KB6 KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT : .::: : ....::::...::: .. :. NP_002 KPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 99 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:45:46 2016 done: Fri Nov 4 23:45:47 2016 Total Scan time: 4.120 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]