FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6751, 104 aa 1>>>pF1KB6751 104 - 104 aa - 104 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7182+/-0.00032; mu= 11.6976+/- 0.020 mean_var=47.9253+/- 9.646, 0's: 0 Z-trim(114.9): 8 B-trim: 1338 in 2/50 Lambda= 0.185264 statistics sampled from 24962 (24970) to 24962 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.293), width: 16 Scan time: 3.350 The best scores are: opt bits E(85289) NP_000272 (OMIM: 126090,264070) pterin-4-alpha-car ( 104) 699 193.9 4.1e-50 NP_001309933 (OMIM: 126090,264070) pterin-4-alpha- ( 104) 506 142.3 1.4e-34 NP_115527 (OMIM: 609836) pterin-4-alpha-carbinolam ( 130) 468 132.1 1.9e-31 NP_001276726 (OMIM: 126090,264070) pterin-4-alpha- ( 55) 361 103.4 3.7e-23 >>NP_000272 (OMIM: 126090,264070) pterin-4-alpha-carbino (104 aa) initn: 699 init1: 699 opt: 699 Z-score: 1020.7 bits: 193.9 E(85289): 4.1e-50 Smith-Waterman score: 699; 100.0% identity (100.0% similar) in 104 aa overlap (1-104:1-104) 10 20 30 40 50 60 pF1KB6 MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKL 10 20 30 40 50 60 70 80 90 100 pF1KB6 DHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT :::::::::::::::::::::::::::::::::::::::::::: NP_000 DHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT 70 80 90 100 >>NP_001309933 (OMIM: 126090,264070) pterin-4-alpha-carb (104 aa) initn: 506 init1: 506 opt: 506 Z-score: 741.9 bits: 142.3 E(85289): 1.4e-34 Smith-Waterman score: 506; 100.0% identity (100.0% similar) in 73 aa overlap (1-73:1-73) 10 20 30 40 50 60 pF1KB6 MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKL 10 20 30 40 50 60 70 80 90 100 pF1KB6 DHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT ::::::::::::: NP_001 DHHPEWFNVYNKVSRLQASGVQQYHLLSWFSSLPTTDLGTCQPP 70 80 90 100 >>NP_115527 (OMIM: 609836) pterin-4-alpha-carbinolamine (130 aa) initn: 479 init1: 462 opt: 468 Z-score: 685.5 bits: 132.1 E(85289): 1.9e-31 Smith-Waterman score: 468; 61.2% identity (93.2% similar) in 103 aa overlap (1-103:28-130) 10 20 30 pF1KB6 MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDA :.. .:::.::::.: . .:.:.::.:: ::: NP_115 MAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 IFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLA :.:.: :..::.:::::.::::::::..::::::::::::.:::..:.:. :...:..:: NP_115 IYKEFSFHNFNQAFGFMSRVALQAEKMNHHPEWFNVYNKVQITLTSHDCGELTKKDVKLA 70 80 90 100 110 120 100 pF1KB6 SFIEQVAVSMT .:::..:.:. NP_115 KFIEKAAASV 130 >>NP_001276726 (OMIM: 126090,264070) pterin-4-alpha-carb (55 aa) initn: 361 init1: 361 opt: 361 Z-score: 536.8 bits: 103.4 E(85289): 3.7e-23 Smith-Waterman score: 361; 100.0% identity (100.0% similar) in 55 aa overlap (50-104:1-55) 20 30 40 50 60 70 pF1KB6 LRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLST :::::::::::::::::::::::::::::: NP_001 MTRVALQAEKLDHHPEWFNVYNKVHITLST 10 20 30 80 90 100 pF1KB6 HECAGLSERDINLASFIEQVAVSMT ::::::::::::::::::::::::: NP_001 HECAGLSERDINLASFIEQVAVSMT 40 50 104 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:47:34 2016 done: Fri Nov 4 23:47:34 2016 Total Scan time: 3.350 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]