FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6753, 105 aa 1>>>pF1KB6753 105 - 105 aa - 105 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6603+/-0.000358; mu= 12.9617+/- 0.022 mean_var=67.4247+/-13.383, 0's: 0 Z-trim(114.5): 82 B-trim: 720 in 1/53 Lambda= 0.156194 statistics sampled from 24215 (24324) to 24215 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.285), width: 16 Scan time: 3.650 The best scores are: opt bits E(85289) NP_005611 (OMIM: 603114) protein S100-A11 [Homo sa ( 105) 680 161.5 2.3e-40 NP_006262 (OMIM: 176940) protein S100-A1 [Homo sap ( 94) 265 67.9 3e-12 NP_002957 (OMIM: 114085) protein S100-A10 [Homo sa ( 97) 254 65.5 1.7e-11 NP_005971 (OMIM: 600614) protein S100-P [Homo sapi ( 95) 250 64.6 3.1e-11 XP_011541546 (OMIM: 610103) PREDICTED: protein S10 ( 99) 241 62.5 1.3e-10 XP_016864661 (OMIM: 610103) PREDICTED: protein S10 ( 99) 241 62.5 1.3e-10 XP_011541542 (OMIM: 610103) PREDICTED: protein S10 ( 99) 241 62.5 1.3e-10 XP_011541541 (OMIM: 610103) PREDICTED: protein S10 ( 99) 241 62.5 1.3e-10 XP_016864662 (OMIM: 610103) PREDICTED: protein S10 ( 99) 241 62.5 1.3e-10 XP_016864660 (OMIM: 610103) PREDICTED: protein S10 ( 99) 241 62.5 1.3e-10 XP_011541543 (OMIM: 610103) PREDICTED: protein S10 ( 99) 241 62.5 1.3e-10 NP_570128 (OMIM: 610103) protein S100-Z [Homo sapi ( 99) 241 62.5 1.3e-10 XP_011541547 (OMIM: 610103) PREDICTED: protein S10 ( 99) 241 62.5 1.3e-10 XP_016883913 (OMIM: 176990) PREDICTED: protein S10 ( 92) 237 61.6 2.3e-10 NP_006263 (OMIM: 176990) protein S100-B [Homo sapi ( 92) 237 61.6 2.3e-10 NP_062427 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 216 56.9 6.6e-09 NP_002952 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 216 56.9 6.6e-09 NP_005612 (OMIM: 603112) protein S100-A12 [Homo sa ( 92) 203 54.0 4.7e-08 XP_011507833 (OMIM: 616284) PREDICTED: filaggrin-2 (2239) 215 57.9 7.4e-08 NP_001014364 (OMIM: 616284) filaggrin-2 [Homo sapi (2391) 215 57.9 7.8e-08 NP_002956 (OMIM: 123886) protein S100-A9 [Homo sap ( 114) 197 52.7 1.4e-07 NP_005969 (OMIM: 176993) protein S100-A2 [Homo sap ( 97) 189 50.8 4.4e-07 NP_002951 (OMIM: 176992) protein S100-A3 [Homo sap ( 101) 189 50.8 4.5e-07 XP_016857520 (OMIM: 176991) PREDICTED: protein S10 ( 92) 184 49.7 9.2e-07 XP_016857521 (OMIM: 176991) PREDICTED: protein S10 ( 92) 184 49.7 9.2e-07 NP_002953 (OMIM: 176991) protein S100-A5 [Homo sap ( 92) 184 49.7 9.2e-07 XP_011508162 (OMIM: 176991) PREDICTED: protein S10 ( 104) 184 49.7 1e-06 XP_016857519 (OMIM: 176991) PREDICTED: protein S10 ( 110) 184 49.7 1e-06 XP_016857518 (OMIM: 176991) PREDICTED: protein S10 ( 133) 184 49.8 1.2e-06 XP_016857522 (OMIM: 114110) PREDICTED: protein S10 ( 90) 178 48.3 2.3e-06 NP_055439 (OMIM: 114110) protein S100-A6 [Homo sap ( 90) 178 48.3 2.3e-06 NP_005970 (OMIM: 601989) protein S100-A13 [Homo sa ( 98) 174 47.4 4.6e-06 XP_016857525 (OMIM: 601989) PREDICTED: protein S10 ( 98) 174 47.4 4.6e-06 XP_016857523 (OMIM: 601989) PREDICTED: protein S10 ( 98) 174 47.4 4.6e-06 NP_001019383 (OMIM: 601989) protein S100-A13 [Homo ( 98) 174 47.4 4.6e-06 NP_001019382 (OMIM: 601989) protein S100-A13 [Homo ( 98) 174 47.4 4.6e-06 XP_011508165 (OMIM: 601989) PREDICTED: protein S10 ( 98) 174 47.4 4.6e-06 NP_001019381 (OMIM: 601989) protein S100-A13 [Homo ( 98) 174 47.4 4.6e-06 XP_005245491 (OMIM: 601989) PREDICTED: protein S10 ( 98) 174 47.4 4.6e-06 XP_011508164 (OMIM: 601989) PREDICTED: protein S10 ( 98) 174 47.4 4.6e-06 XP_011508166 (OMIM: 601989) PREDICTED: protein S10 ( 98) 174 47.4 4.6e-06 NP_001019384 (OMIM: 601989) protein S100-A13 [Homo ( 98) 174 47.4 4.6e-06 XP_016857524 (OMIM: 601989) PREDICTED: protein S10 ( 98) 174 47.4 4.6e-06 NP_002954 (OMIM: 600353) protein S100-A7 [Homo sap ( 101) 162 44.8 3.1e-05 NP_002007 (OMIM: 135940,146700,605803) filaggrin [ (4061) 179 50.0 3.2e-05 NP_009044 (OMIM: 190370) trichohyalin [Homo sapien (1943) 173 48.4 4.7e-05 NP_004048 (OMIM: 302020) protein S100-G [Homo sapi ( 79) 156 43.3 6.5e-05 XP_016885330 (OMIM: 302020) PREDICTED: protein S10 ( 79) 156 43.3 6.5e-05 NP_001116437 (OMIM: 613259) repetin [Homo sapiens] ( 784) 164 46.0 9.9e-05 NP_057274 (OMIM: 611312) cornulin [Homo sapiens] ( 495) 159 44.7 0.00016 >>NP_005611 (OMIM: 603114) protein S100-A11 [Homo sapien (105 aa) initn: 680 init1: 680 opt: 680 Z-score: 845.7 bits: 161.5 E(85289): 2.3e-40 Smith-Waterman score: 680; 100.0% identity (100.0% similar) in 105 aa overlap (1-105:1-105) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL 10 20 30 40 50 60 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT ::::::::::::::::::::::::::::::::::::::::::::: NP_005 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT 70 80 90 100 >>NP_006262 (OMIM: 176940) protein S100-A1 [Homo sapiens (94 aa) initn: 258 init1: 244 opt: 265 Z-score: 340.9 bits: 67.9 E(85289): 3e-12 Smith-Waterman score: 265; 43.2% identity (79.5% similar) in 88 aa overlap (8-95:3-90) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL .: : .:.:: ::. ..::.: .: ::: :. ...:::..: ::: .. NP_006 MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :..::.:: :.::..::.:.. :...:..::.. : NP_006 DKVMKELDENGDGEVDFQEYVVLVAALTVACNNFFWENS 60 70 80 90 >>NP_002957 (OMIM: 114085) protein S100-A10 [Homo sapien (97 aa) initn: 235 init1: 163 opt: 254 Z-score: 327.4 bits: 65.5 E(85289): 1.7e-11 Smith-Waterman score: 254; 40.0% identity (75.6% similar) in 90 aa overlap (7-96:2-88) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL :.. :. .:... .:.:.:: :: :.: .. .:. :. .: .::::: .. NP_002 MPSQMEHAMETMMFTFHKFAGDKGY---LTKEDLRVLMEKEFPGFLENQKDPLAV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :..:: :: ::.. :. :..::.::..::.: :. NP_002 DKIMKDLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK 60 70 80 90 >>NP_005971 (OMIM: 600614) protein S100-P [Homo sapiens] (95 aa) initn: 250 init1: 250 opt: 250 Z-score: 322.6 bits: 64.6 E(85289): 3.1e-11 Smith-Waterman score: 250; 40.7% identity (74.7% similar) in 91 aa overlap (8-98:2-92) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL :: : . .: ::..:.:..: . ::.: :. .:. :: .: .. :: .. NP_005 MTELETAMGMIIDVFSRYSGSEGSTQTLTKGELKVLMEKELPGFLQSGKDKDAV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :...: ::.:.:.:.:::::. ...... ::: : :: NP_005 DKLLKDLDANGDAQVDFSEFIVFVAAITSACHKYFEKAGLK 60 70 80 90 >>XP_011541546 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 256 init1: 241 opt: 241 Z-score: 311.4 bits: 62.5 E(85289): 1.3e-10 Smith-Waterman score: 241; 31.6% identity (76.5% similar) in 98 aa overlap (7-104:2-99) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL ::. : ....: .:..:.::. . ::: :. ... ::. : . ::. .. XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :.... ::.:.:...::.::. ....:..::.: :.. . .. . XP_011 DKIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_016864661 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 256 init1: 241 opt: 241 Z-score: 311.4 bits: 62.5 E(85289): 1.3e-10 Smith-Waterman score: 241; 31.6% identity (76.5% similar) in 98 aa overlap (7-104:2-99) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL ::. : ....: .:..:.::. . ::: :. ... ::. : . ::. .. XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :.... ::.:.:...::.::. ....:..::.: :.. . .. . XP_016 DKIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_011541542 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 256 init1: 241 opt: 241 Z-score: 311.4 bits: 62.5 E(85289): 1.3e-10 Smith-Waterman score: 241; 31.6% identity (76.5% similar) in 98 aa overlap (7-104:2-99) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL ::. : ....: .:..:.::. . ::: :. ... ::. : . ::. .. XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :.... ::.:.:...::.::. ....:..::.: :.. . .. . XP_011 DKIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_011541541 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 256 init1: 241 opt: 241 Z-score: 311.4 bits: 62.5 E(85289): 1.3e-10 Smith-Waterman score: 241; 31.6% identity (76.5% similar) in 98 aa overlap (7-104:2-99) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL ::. : ....: .:..:.::. . ::: :. ... ::. : . ::. .. XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :.... ::.:.:...::.::. ....:..::.: :.. . .. . XP_011 DKIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_016864662 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 256 init1: 241 opt: 241 Z-score: 311.4 bits: 62.5 E(85289): 1.3e-10 Smith-Waterman score: 241; 31.6% identity (76.5% similar) in 98 aa overlap (7-104:2-99) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL ::. : ....: .:..:.::. . ::: :. ... ::. : . ::. .. XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :.... ::.:.:...::.::. ....:..::.: :.. . .. . XP_016 DKIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 >>XP_016864660 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa) initn: 256 init1: 241 opt: 241 Z-score: 311.4 bits: 62.5 E(85289): 1.3e-10 Smith-Waterman score: 241; 31.6% identity (76.5% similar) in 98 aa overlap (7-104:2-99) 10 20 30 40 50 60 pF1KB6 MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVL ::. : ....: .:..:.::. . ::: :. ... ::. : . ::. .. XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLV 10 20 30 40 50 70 80 90 100 pF1KB6 DRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT :.... ::.:.:...::.::. ....:..::.: :.. . .. . XP_016 DKIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK 60 70 80 90 105 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:48:52 2016 done: Fri Nov 4 23:48:53 2016 Total Scan time: 3.650 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]