FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6761, 109 aa 1>>>pF1KB6761 109 - 109 aa - 109 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7094+/-0.000267; mu= 13.0134+/- 0.017 mean_var=57.0287+/-11.085, 0's: 0 Z-trim(120.5): 69 B-trim: 318 in 2/51 Lambda= 0.169835 statistics sampled from 35835 (35904) to 35835 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.421), width: 16 Scan time: 4.690 The best scores are: opt bits E(85289) NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 666 170.2 5.5e-43 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 489 126.8 6.2e-30 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 449 117.0 5.4e-27 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 443 115.5 1.5e-26 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 422 110.4 5.4e-25 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 259 70.4 5.4e-13 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 255 69.4 1.1e-12 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 248 67.7 3.5e-12 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 248 67.7 3.5e-12 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 231 63.6 7.7e-11 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 231 63.6 7.7e-11 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 231 63.6 7.7e-11 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 225 62.1 1.7e-10 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 225 62.1 1.7e-10 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 217 60.1 6.5e-10 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 218 60.5 7e-10 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 218 60.5 7e-10 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 214 59.4 1.1e-09 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 201 56.3 1.4e-08 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 201 56.3 1.5e-08 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 197 55.2 2e-08 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 196 55.0 2.4e-08 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 196 55.0 2.4e-08 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 195 54.8 3.2e-08 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 196 55.1 3.5e-08 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 186 52.5 1.3e-07 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 186 52.5 1.3e-07 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 179 50.8 4.4e-07 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 178 50.7 6.4e-07 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 178 50.7 6.4e-07 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 176 50.1 8.4e-07 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 176 50.2 9.8e-07 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 173 49.4 1.2e-06 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 169 48.5 2.9e-06 NP_001265665 (OMIM: 187011) C-C motif chemokine 5 ( 154) 166 47.8 5.9e-06 NP_002987 (OMIM: 601880) fractalkine isoform 1 pre ( 397) 168 48.6 8.9e-06 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 155 45.0 2.8e-05 NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 154 44.8 3.6e-05 NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 154 44.8 3.6e-05 XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 154 44.8 3.6e-05 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 150 43.7 6.1e-05 NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 148 43.1 6.2e-05 NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 148 43.1 6.2e-05 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 149 43.5 7.7e-05 NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 148 43.2 7.9e-05 XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 142 41.8 0.00026 NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 142 41.8 0.00026 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 140 41.3 0.00034 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 136 40.3 0.00067 NP_000600 (OMIM: 600835,609423) stromal cell-deriv ( 93) 135 40.0 0.00076 >>NP_006264 (OMIM: 158106) C-C motif chemokine 7 precurs (99 aa) initn: 666 init1: 666 opt: 666 Z-score: 892.8 bits: 170.2 E(85289): 5.5e-43 Smith-Waterman score: 666; 100.0% identity (100.0% similar) in 99 aa overlap (11-109:1-99) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES :::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES 10 20 30 40 50 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL ::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL 60 70 80 90 >>NP_002973 (OMIM: 158105,182940,607948,609423) C-C moti (99 aa) initn: 489 init1: 489 opt: 489 Z-score: 658.4 bits: 126.8 E(85289): 6.2e-30 Smith-Waterman score: 489; 74.5% identity (84.7% similar) in 98 aa overlap (11-108:1-98) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES ::.::::::::: ::.: ::::::: .::. .:::: : :.:: ::: : NP_002 MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLAS 10 20 30 40 50 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL ::: :::.::.::::::: . ::::::: :::::: : ::::.::::: NP_002 YRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT 60 70 80 90 >>NP_002977 (OMIM: 600807,601156,609423) eotaxin precurs (97 aa) initn: 356 init1: 342 opt: 449 Z-score: 605.6 bits: 117.0 E(85289): 5.4e-27 Smith-Waterman score: 449; 69.4% identity (85.7% similar) in 98 aa overlap (11-108:1-96) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES ::.::::: ::: :::::::::: :... ::::. . :.::: ::::: NP_002 MKVSAALLWLLLIAAAFSPQGLAGPASV--PTTCCFNLANRKIPLQRLES 10 20 30 40 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL ::: ::..::..:::::::: :.::::: .::::: ::.::.:. ::: NP_002 YRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP 50 60 70 80 90 >>NP_005614 (OMIM: 602283) C-C motif chemokine 8 precurs (99 aa) initn: 459 init1: 439 opt: 443 Z-score: 597.5 bits: 115.5 E(85289): 1.5e-26 Smith-Waterman score: 443; 65.3% identity (81.6% similar) in 98 aa overlap (11-108:1-98) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES ::.::::::::: ::.::::::::: ... :::. ::.::: ::::: NP_005 MKVSAALLCLLLMAATFSPQGLAQPDSVSIPITCCFNVINRKIPIQRLES 10 20 30 40 50 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL : : :. .::.:::::::: ::.:::: ..::.: :::::. :. : NP_005 YTRITNIQCPKEAVIFKTKRGKEVCADPKERWVRDSMKHLDQIFQNLKP 60 70 80 90 >>NP_005399 (OMIM: 601391) C-C motif chemokine 13 precur (98 aa) initn: 420 init1: 231 opt: 422 Z-score: 569.7 bits: 110.4 E(85289): 5.4e-25 Smith-Waterman score: 422; 64.3% identity (85.7% similar) in 98 aa overlap (11-108:1-97) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES ::.::.:::::: .:::.::::::: ..:. .:::. : .::: :::.: NP_005 MKVSAVLLCLLLMTAAFNPQGLAQPDALNVPSTCCFTFSSKKISLQRLKS 10 20 30 40 50 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL : ::: .::..::::.::: ::::::: .::::..:::: .:..: : NP_005 YVITTS-RCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT 60 70 80 90 >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 283 init1: 146 opt: 259 Z-score: 354.3 bits: 70.4 E(85289): 5.4e-13 Smith-Waterman score: 259; 38.5% identity (73.6% similar) in 91 aa overlap (11-101:1-90) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES :: ...: ::. .::: .:. :.: . :.::. . .:.:.. . . NP_002 MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVD 10 20 30 40 50 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL : .: :: : . ::.:.:: .:..::::...:::... :. NP_002 YYET-SSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN 60 70 80 90 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 260 init1: 145 opt: 255 Z-score: 349.0 bits: 69.4 E(85289): 1.1e-12 Smith-Waterman score: 255; 38.5% identity (72.5% similar) in 91 aa overlap (11-101:1-90) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES :: ...: ::. .::: .:. :.: . :.::. . .:.:.. . . NP_996 MKLCVTVLSLLVLVAAFCSLALSAPMGSDPPTACCFSYTARKLPRNFVVD 10 20 30 40 50 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL : .: :: : . ::.:.:: :..::::...:::... :. NP_996 YYET-SSLCSQPAVVFQTKRGKQVCADPSESWVQEYVYDLELN 60 70 80 90 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 229 init1: 140 opt: 248 Z-score: 339.6 bits: 67.7 E(85289): 3.5e-12 Smith-Waterman score: 248; 37.4% identity (74.7% similar) in 91 aa overlap (11-101:1-90) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES :..:.: : .:: . :. : :. :.. .: :.::. . ...::.. . . NP_001 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIAD 10 20 30 40 50 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL : .: ::.: . .::: :: ...::::...::: ... :. NP_001 YFET-SSQCSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 229 init1: 140 opt: 248 Z-score: 339.6 bits: 67.7 E(85289): 3.5e-12 Smith-Waterman score: 248; 37.4% identity (74.7% similar) in 91 aa overlap (11-101:1-90) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES :..:.: : .:: . :. : :. :.. .: :.::. . ...::.. . . NP_066 MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIAD 10 20 30 40 50 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL : .: ::.: . .::: :: ...::::...::: ... :. NP_066 YFET-SSQCSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 >>XP_011514761 (OMIM: 602495) PREDICTED: C-C motif chemo (119 aa) initn: 258 init1: 222 opt: 231 Z-score: 315.6 bits: 63.6 E(85289): 7.7e-11 Smith-Waterman score: 231; 36.0% identity (65.0% similar) in 100 aa overlap (11-108:5-99) 10 20 30 40 50 60 pF1KB6 MWKPMPSPSNMKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLES : ..:: : . : . : : .. . ::. :..:.::..:. : XP_011 MAGLMTIVTSLLFLGVCAHHIIPTG-----SVVIPSPCCMFFVSKRIPENRVVS 10 20 30 40 70 80 90 100 pF1KB6 YRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQ--TPKL :. .. : : . .::: :: ...:.:: :.::: .::.:: : . .:. XP_011 YQLSSRSTCLKAGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPV 50 60 70 80 90 100 XP_011 QRYPGNQTTC 110 109 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:26:52 2016 done: Sat Nov 5 20:26:53 2016 Total Scan time: 4.690 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]