FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6763, 113 aa 1>>>pF1KB6763 113 - 113 aa - 113 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5664+/-0.000282; mu= 14.0553+/- 0.018 mean_var=54.9561+/-10.587, 0's: 0 Z-trim(118.3): 57 B-trim: 136 in 2/50 Lambda= 0.173008 statistics sampled from 30988 (31046) to 30988 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.364), width: 16 Scan time: 3.760 The best scores are: opt bits E(85289) NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 754 195.2 1.8e-50 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 541 142.1 2e-34 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 312 85.0 3.5e-17 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 269 74.2 5e-14 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 243 67.6 3.9e-12 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 243 67.6 3.9e-12 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 235 65.6 1.6e-11 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 220 61.9 2.1e-10 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 202 57.4 4.6e-09 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 198 56.4 9.4e-09 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 190 54.4 3.7e-08 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 190 54.4 3.7e-08 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 176 50.9 4.5e-07 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 171 49.7 1e-06 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 171 49.7 1.3e-06 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 171 49.7 1.3e-06 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 168 48.9 1.7e-06 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 168 48.9 1.7e-06 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 168 48.9 1.8e-06 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 164 47.9 3.6e-06 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 163 47.7 4.1e-06 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 163 47.7 4.1e-06 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 163 47.7 4.9e-06 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 163 47.7 4.9e-06 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 163 47.7 4.9e-06 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 163 47.8 5.8e-06 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 160 46.9 7.1e-06 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 158 46.4 9.1e-06 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 148 43.9 5.6e-05 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 147 43.8 8.6e-05 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 147 43.8 9.1e-05 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 142 42.4 0.00016 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 142 42.5 0.00019 XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 142 42.5 0.00019 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 139 41.7 0.00027 NP_002986 (OMIM: 600250) lymphotactin precursor [H ( 114) 136 41.0 0.00051 XP_011508167 (OMIM: 600250) PREDICTED: lymphotacti ( 114) 136 41.0 0.00051 NP_003166 (OMIM: 604828) cytokine SCM-1 beta precu ( 114) 136 41.0 0.00051 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 135 40.7 0.00052 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 128 39.0 0.0019 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 122 37.5 0.0053 >>NP_116741 (OMIM: 601393) C-C motif chemokine 15 prepro (113 aa) initn: 754 init1: 754 opt: 754 Z-score: 1026.9 bits: 195.2 E(85289): 1.8e-50 Smith-Waterman score: 754; 100.0% identity (100.0% similar) in 113 aa overlap (1-113:1-113) 10 20 30 40 50 60 pF1KB6 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 SIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 SIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI 70 80 90 100 110 >>NP_665905 (OMIM: 602494) C-C motif chemokine 23 isofor (120 aa) initn: 541 init1: 308 opt: 541 Z-score: 739.2 bits: 142.1 E(85289): 2e-34 Smith-Waterman score: 541; 74.5% identity (88.2% similar) in 110 aa overlap (1-109:1-110) 10 20 30 40 50 pF1KB6 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLNSFH-FAADCCTSYIS ::::::::::::::..:::::. :.:::::.:::::::::::.:. :: .:::: :: NP_665 MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 QSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI .::::::..:::::.::::::::::::::::. ::.:: :: ::. :: NP_665 RSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN 70 80 90 100 110 120 >>NP_005055 (OMIM: 602494) C-C motif chemokine 23 isofor (137 aa) initn: 524 init1: 308 opt: 312 Z-score: 429.5 bits: 85.0 E(85289): 3.5e-17 Smith-Waterman score: 498; 64.6% identity (77.2% similar) in 127 aa overlap (1-109:1-127) 10 20 30 40 pF1KB6 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLN--------------- ::::::::::::::..:::::. :.:::::.:::::::::::.:. NP_005 MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 --SFH-FAADCCTSYISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQ .:: .:::: :: .::::::..:::::.::::::::::::::::. ::.:: :: NP_005 AAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQ 70 80 90 100 110 120 110 pF1KB6 DCMKKLKPYSI ::. :: NP_005 VCMRMLKLDTRIKTRKN 130 >>NP_116738 (OMIM: 601392) C-C motif chemokine 14 isofor (109 aa) initn: 267 init1: 216 opt: 269 Z-score: 372.9 bits: 74.2 E(85289): 5e-14 Smith-Waterman score: 269; 36.4% identity (75.5% similar) in 110 aa overlap (1-109:1-107) 10 20 30 40 50 pF1KB6 MKVSVAALSCLMLVAV-LGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYIS ::.::::. ..:... ::.... .... . . :. :. .: . .: ..:: .: . NP_116 MKISVAAIPFFLLITIALGTKTESSSQTGGKPKVVKIQLK--LVGGPYH-PSECCFTYTT 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 QSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI .:: . . .:.::.:.:::::..:.::.:..::..:: ::: .: .: NP_116 YKIPRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 60 70 80 90 100 >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 280 init1: 233 opt: 243 Z-score: 338.8 bits: 67.6 E(85289): 3.9e-12 Smith-Waterman score: 243; 48.3% identity (69.0% similar) in 87 aa overlap (27-109:6-90) 10 20 30 40 50 pF1KB6 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAAD----CCTS : ... . : : :. : .::: :: : NP_066 MQVSTAALAVLLCTMALCNQVL--SAPLAADTPTACCFS 10 20 30 60 70 80 90 100 110 pF1KB6 YISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI : :..:: ... .::::::.::::.::::::.:::::: :: :: .. :. NP_066 YTSRQIPQNFIADYFETSSQCSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 40 50 60 70 80 90 >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 280 init1: 233 opt: 243 Z-score: 338.8 bits: 67.6 E(85289): 3.9e-12 Smith-Waterman score: 243; 48.3% identity (69.0% similar) in 87 aa overlap (27-109:6-90) 10 20 30 40 50 pF1KB6 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAAD----CCTS : ... . : : :. : .::: :: : NP_001 MQVSTAALAVLLCTMALCNQVL--SAPLAADTPTACCFS 10 20 30 60 70 80 90 100 110 pF1KB6 YISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI : :..:: ... .::::::.::::.::::::.:::::: :: :: .. :. NP_001 YTSRQIPQNFIADYFETSSQCSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 40 50 60 70 80 90 >>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa) initn: 275 init1: 233 opt: 235 Z-score: 328.1 bits: 65.6 E(85289): 1.6e-11 Smith-Waterman score: 237; 42.2% identity (66.1% similar) in 109 aa overlap (1-109:1-89) 10 20 30 40 50 60 pF1KB6 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQ :.::.:::. :. . .: .: :. ..: ..:.. :: :: :. NP_002 MQVSTAALAVLLCTMALCNQ--FS---------ASLAADTPTA---------CCFSYTSR 10 20 30 40 70 80 90 100 110 pF1KB6 SIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI .:: ... .::::::.:::::::::::..::::: :: :: .. :. NP_002 QIPQNFIADYFETSSQCSKPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA 50 60 70 80 90 >>NP_116739 (OMIM: 601392) C-C motif chemokine 14 isofor (93 aa) initn: 273 init1: 216 opt: 220 Z-score: 307.8 bits: 61.9 E(85289): 2.1e-10 Smith-Waterman score: 237; 35.5% identity (67.3% similar) in 110 aa overlap (1-109:1-91) 10 20 30 40 50 pF1KB6 MKVSVAALSCLMLVAV-LGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYIS ::.::::. ..:... ::.... . :. : .: ..:: .: . NP_116 MKISVAAIPFFLLITIALGTKTESS---------SRGP---------YH-PSECCFTYTT 10 20 30 40 60 70 80 90 100 110 pF1KB6 QSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI .:: . . .:.::.:.:::::..:.::.:..::..:: ::: .: .: NP_116 YKIPRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 50 60 70 80 90 >>NP_002979 (OMIM: 603757) C-C motif chemokine 18 precur (89 aa) initn: 236 init1: 202 opt: 202 Z-score: 283.8 bits: 57.4 E(85289): 4.6e-09 Smith-Waterman score: 202; 50.9% identity (71.9% similar) in 57 aa overlap (53-109:30-86) 30 40 50 60 70 80 pF1KB6 FTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQSIPCSLMKSYFETSSECSKPGV :: : : .:: ... .: ::: .: :::: NP_002 MKGLAAALLVLVCTMALCSCAQVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKPGV 10 20 30 40 50 90 100 110 pF1KB6 IFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI :.:::.:::.:: :. :: .. :: NP_002 ILLTKRGRQICADPNKKWVQKYISDLKLNA 60 70 80 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 246 init1: 197 opt: 198 Z-score: 278.2 bits: 56.4 E(85289): 9.4e-09 Smith-Waterman score: 202; 37.6% identity (59.6% similar) in 109 aa overlap (1-109:1-90) 10 20 30 40 50 60 pF1KB6 MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQ ::. :..:: :.:::. : . : . : : : :: :: .. NP_996 MKLCVTVLSLLVLVAA------FCSLALSAPMGSDPPTA-------------CCFSYTAR 10 20 30 40 70 80 90 100 110 pF1KB6 SIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI ..: ... .:.:::: ::.:.:.: ::.:.:::: :: ::. . :. NP_996 KLPRNFVVDYYETSSLCSQPAVVFQTKRGKQVCADPSESWVQEYVYDLELN 50 60 70 80 90 113 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:51:09 2016 done: Fri Nov 4 23:51:09 2016 Total Scan time: 3.760 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]