FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6764, 148 aa 1>>>pF1KB6764 148 - 148 aa - 148 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9027+/-0.000362; mu= 13.4657+/- 0.022 mean_var=57.1546+/-11.697, 0's: 0 Z-trim(112.8): 25 B-trim: 694 in 1/51 Lambda= 0.169648 statistics sampled from 21793 (21812) to 21793 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.256), width: 16 Scan time: 4.540 The best scores are: opt bits E(85289) NP_000230 (OMIM: 105200,153450) lysozyme C precurs ( 148) 1028 259.5 1.4e-69 NP_776246 (OMIM: 612749) sperm acrosome membrane-a ( 215) 500 130.4 1.5e-30 XP_016885001 (OMIM: 300593) PREDICTED: sperm acros ( 159) 482 125.9 2.5e-29 NP_995328 (OMIM: 300593) sperm acrosome-associated ( 159) 482 125.9 2.5e-29 NP_898881 (OMIM: 612748) lysozyme-like protein 2 [ ( 194) 482 126.0 3e-29 NP_065159 (OMIM: 612751) lysozyme-like protein 6 p ( 148) 428 112.7 2.2e-25 NP_001186880 (OMIM: 612751) lysozyme-like protein ( 148) 428 112.7 2.2e-25 XP_016861195 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 382 101.4 5.4e-22 NP_653235 (OMIM: 612750) lysozyme-like protein 4 p ( 146) 382 101.4 5.4e-22 NP_001291315 (OMIM: 612750) lysozyme-like protein ( 146) 382 101.4 5.4e-22 XP_016861194 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 382 101.4 5.4e-22 NP_001304155 (OMIM: 612749) sperm acrosome membran ( 112) 359 95.7 2.2e-20 NP_001304154 (OMIM: 612749) sperm acrosome membran ( 123) 355 94.8 4.6e-20 NP_002280 (OMIM: 149750) alpha-lactalbumin precurs ( 142) 334 89.7 1.8e-18 XP_006719458 (OMIM: 149750) PREDICTED: alpha-lacta ( 149) 334 89.7 1.9e-18 XP_011517608 (OMIM: 612748) PREDICTED: lysozyme-li ( 181) 334 89.7 2.2e-18 XP_011531657 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 321 86.5 1.7e-17 XP_011517609 (OMIM: 612748) PREDICTED: lysozyme-li ( 163) 319 86.0 2.6e-17 >>NP_000230 (OMIM: 105200,153450) lysozyme C precursor [ (148 aa) initn: 1028 init1: 1028 opt: 1028 Z-score: 1370.2 bits: 259.5 E(85289): 1.4e-69 Smith-Waterman score: 1028; 99.3% identity (100.0% similar) in 148 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB6 MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TNYNAGDRSTDYGIFQINSRYWCNDGKNPGAVNACHLSCSALLQDNIADAVACAKRVVRD :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_000 TNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRD 70 80 90 100 110 120 130 140 pF1KB6 PQGIRAWVAWRNRCQNRDVRQYVQGCGV :::::::::::::::::::::::::::: NP_000 PQGIRAWVAWRNRCQNRDVRQYVQGCGV 130 140 >>NP_776246 (OMIM: 612749) sperm acrosome membrane-assoc (215 aa) initn: 478 init1: 222 opt: 500 Z-score: 669.4 bits: 130.4 E(85289): 1.5e-30 Smith-Waterman score: 500; 48.6% identity (78.5% similar) in 144 aa overlap (3-146:73-213) 10 20 30 pF1KB6 MKALIVLGLVLLSVTVQGKVFERCELARTLKR ::. : :: . ..:.. ::::::.:. NP_776 SGGGSTSAAGIEARSRALRRRWCPAGIMLLALVCLLSCLLPSS-EAKLYGRCELARVLHD 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB6 LGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKNPGAV .:.::::: :::.:.::: . ::.:. : .:.: : ::. :::::::: ::.. .:.. NP_776 FGLDGYRGYSLADWVCLAYFTSGFNAAALDYEA-DGSTNNGIFQINSRRWCSN-LTPNVP 110 120 130 140 150 100 110 120 130 140 pF1KB6 NACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV :.:.. :: ::. :. :.: :: .....:::. : :::..::..:. ..:.:: NP_776 NVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGYWEAWRHHCQGKDLTEWVDGCDF 160 170 180 190 200 210 >>XP_016885001 (OMIM: 300593) PREDICTED: sperm acrosome- (159 aa) initn: 451 init1: 192 opt: 482 Z-score: 647.5 bits: 125.9 E(85289): 2.5e-29 Smith-Waterman score: 482; 42.3% identity (77.9% similar) in 149 aa overlap (1-146:1-147) 10 20 30 40 50 pF1KB6 MKA---LIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYN ::: ..: .:. :::..:..:::::: :.: :..::.: ....:.:.:..:::.. XP_016 MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TRATNYNAGDRSTDYGIFQINSRYWCNDGKNPGAVNACHLSCSALLQDNIADAVACAKRV : ...: : :..:::::.:: .::..: .: : ::..: ::. .: : . :::.. XP_016 TAFVDHNP-DGSSEYGIFQLNSAWWCDNGITPTK-NLCHMDCHDLLNRHILDDIRCAKQI 70 80 90 100 110 120 130 140 pF1KB6 VRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV : . .:. ::..:: .:...:. ....:: XP_016 VSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP 120 130 140 150 >>NP_995328 (OMIM: 300593) sperm acrosome-associated pro (159 aa) initn: 451 init1: 192 opt: 482 Z-score: 647.5 bits: 125.9 E(85289): 2.5e-29 Smith-Waterman score: 482; 42.3% identity (77.9% similar) in 149 aa overlap (1-146:1-147) 10 20 30 40 50 pF1KB6 MKA---LIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYN ::: ..: .:. :::..:..:::::: :.: :..::.: ....:.:.:..:::.. NP_995 MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFD 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 TRATNYNAGDRSTDYGIFQINSRYWCNDGKNPGAVNACHLSCSALLQDNIADAVACAKRV : ...: : :..:::::.:: .::..: .: : ::..: ::. .: : . :::.. NP_995 TAFVDHNP-DGSSEYGIFQLNSAWWCDNGITPTK-NLCHMDCHDLLNRHILDDIRCAKQI 70 80 90 100 110 120 130 140 pF1KB6 VRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV : . .:. ::..:: .:...:. ....:: NP_995 VSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP 120 130 140 150 >>NP_898881 (OMIM: 612748) lysozyme-like protein 2 [Homo (194 aa) initn: 472 init1: 210 opt: 482 Z-score: 646.2 bits: 126.0 E(85289): 3e-29 Smith-Waterman score: 482; 45.6% identity (73.2% similar) in 149 aa overlap (1-148:47-193) 10 20 pF1KB6 MKALIVLGLVLLSVT-VQGKVFERCELART ::: .: :. :: ...:.. ::.::. NP_898 VSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLVTGAESKIYTRCKLAKI 20 30 40 50 60 70 30 40 50 60 70 80 pF1KB6 LKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKNP ..: :.:.: :.::.::.:.: .:::::: : . : : ::::::::: :: :: NP_898 FSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTV-LDDGSIDYGIFQINSFAWCRRGKLK 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB6 GAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV : ::..::::. :...::. :::..:.. ::. : .:...:..::. .. . : : NP_898 -ENNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS 140 150 160 170 180 190 >>NP_065159 (OMIM: 612751) lysozyme-like protein 6 precu (148 aa) initn: 420 init1: 178 opt: 428 Z-score: 576.5 bits: 112.7 E(85289): 2.2e-25 Smith-Waterman score: 428; 42.1% identity (69.7% similar) in 145 aa overlap (2-146:3-145) 10 20 30 40 50 pF1KB6 MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTR :::.. . . . :.... ::.::..:. .::..: ::..:.::: :: .: NP_065 MTKALLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNIS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ATNYNAGDRSTDYGIFQINSRYWCNDGKNPGAVNACHLSCSALLQDNIADAVACAKRVVR : :: : : :::.:::::.::::: :. . : ::..:. ::. :. .. ::::.: NP_065 KINENA-DGSFDYGLFQINSHYWCNDYKSYSE-NLCHVDCQDLLNPNLLAGIHCAKRIVS 70 80 90 100 110 120 130 140 pF1KB6 DPQGIRAWVAWRNRCQNRDVRQYVQGCGV .:. :: :: .:..: . .. :: NP_065 GARGMNNWVEWRLHCSGRPLFYWLTGCRLR 120 130 140 >>NP_001186880 (OMIM: 612751) lysozyme-like protein 6 pr (148 aa) initn: 420 init1: 178 opt: 428 Z-score: 576.5 bits: 112.7 E(85289): 2.2e-25 Smith-Waterman score: 428; 42.1% identity (69.7% similar) in 145 aa overlap (2-146:3-145) 10 20 30 40 50 pF1KB6 MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTR :::.. . . . :.... ::.::..:. .::..: ::..:.::: :: .: NP_001 MTKALLIYLVSSFLALNQASLISRCDLAQVLQLEDLDGFEGYSLSDWLCLAFVESKFNIS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ATNYNAGDRSTDYGIFQINSRYWCNDGKNPGAVNACHLSCSALLQDNIADAVACAKRVVR : :: : : :::.:::::.::::: :. . : ::..:. ::. :. .. ::::.: NP_001 KINENA-DGSFDYGLFQINSHYWCNDYKSYSE-NLCHVDCQDLLNPNLLAGIHCAKRIVS 70 80 90 100 110 120 130 140 pF1KB6 DPQGIRAWVAWRNRCQNRDVRQYVQGCGV .:. :: :: .:..: . .. :: NP_001 GARGMNNWVEWRLHCSGRPLFYWLTGCRLR 120 130 140 >>XP_016861195 (OMIM: 612750) PREDICTED: lysozyme-like p (146 aa) initn: 404 init1: 191 opt: 382 Z-score: 515.8 bits: 101.4 E(85289): 5.4e-22 Smith-Waterman score: 382; 38.9% identity (65.1% similar) in 149 aa overlap (1-146:1-144) 10 20 30 40 50 pF1KB6 MKALIVLGLVLLSVTVQGK-VFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTR ::: .::.:. :. .: .. :: .:. :. :.: ..: :: ::.::: .:: .: XP_016 MKASVVLSLLGYLVVPSGAYILGRCTVAKKLHDGGLDYFEGYSLENWVCLAYFESKFNPM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ATNYNAGDRSTDYGIFQINSRYWCND-GKNPGAVNACHLSCSALLQDNIADAVACAKRVV : :. . : .:.::. . ::.: :.: ::.::::::. :. .. ::: .: XP_016 AIYENTREGYTGFGLFQMRGSDWCGDHGRN-----RCHMSCSALLNPNLEKTIKCAKTIV 70 80 90 100 110 120 130 140 pF1KB6 RDPQGIRAWVAWRNRCQNRD-VRQYVQGCGV . .:. :: .: :: : . ....:: XP_016 KGKEGMGAWPTWSRYCQYSDTLARWLDGCKL 120 130 140 >>NP_653235 (OMIM: 612750) lysozyme-like protein 4 precu (146 aa) initn: 404 init1: 191 opt: 382 Z-score: 515.8 bits: 101.4 E(85289): 5.4e-22 Smith-Waterman score: 382; 38.9% identity (65.1% similar) in 149 aa overlap (1-146:1-144) 10 20 30 40 50 pF1KB6 MKALIVLGLVLLSVTVQGK-VFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTR ::: .::.:. :. .: .. :: .:. :. :.: ..: :: ::.::: .:: .: NP_653 MKASVVLSLLGYLVVPSGAYILGRCTVAKKLHDGGLDYFEGYSLENWVCLAYFESKFNPM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ATNYNAGDRSTDYGIFQINSRYWCND-GKNPGAVNACHLSCSALLQDNIADAVACAKRVV : :. . : .:.::. . ::.: :.: ::.::::::. :. .. ::: .: NP_653 AIYENTREGYTGFGLFQMRGSDWCGDHGRN-----RCHMSCSALLNPNLEKTIKCAKTIV 70 80 90 100 110 120 130 140 pF1KB6 RDPQGIRAWVAWRNRCQNRD-VRQYVQGCGV . .:. :: .: :: : . ....:: NP_653 KGKEGMGAWPTWSRYCQYSDTLARWLDGCKL 120 130 140 >>NP_001291315 (OMIM: 612750) lysozyme-like protein 4 pr (146 aa) initn: 404 init1: 191 opt: 382 Z-score: 515.8 bits: 101.4 E(85289): 5.4e-22 Smith-Waterman score: 382; 38.9% identity (65.1% similar) in 149 aa overlap (1-146:1-144) 10 20 30 40 50 pF1KB6 MKALIVLGLVLLSVTVQGK-VFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTR ::: .::.:. :. .: .. :: .:. :. :.: ..: :: ::.::: .:: .: NP_001 MKASVVLSLLGYLVVPSGAYILGRCTVAKKLHDGGLDYFEGYSLENWVCLAYFESKFNPM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ATNYNAGDRSTDYGIFQINSRYWCND-GKNPGAVNACHLSCSALLQDNIADAVACAKRVV : :. . : .:.::. . ::.: :.: ::.::::::. :. .. ::: .: NP_001 AIYENTREGYTGFGLFQMRGSDWCGDHGRN-----RCHMSCSALLNPNLEKTIKCAKTIV 70 80 90 100 110 120 130 140 pF1KB6 RDPQGIRAWVAWRNRCQNRD-VRQYVQGCGV . .:. :: .: :: : . ....:: NP_001 KGKEGMGAWPTWSRYCQYSDTLARWLDGCKL 120 130 140 148 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:52:18 2016 done: Fri Nov 4 23:52:19 2016 Total Scan time: 4.540 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]