FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6765, 114 aa 1>>>pF1KB6765 114 - 114 aa - 114 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6539+/-0.00024; mu= 14.5336+/- 0.015 mean_var=65.0282+/-12.588, 0's: 0 Z-trim(123.4): 38 B-trim: 0 in 0/56 Lambda= 0.159046 statistics sampled from 43053 (43099) to 43053 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.841), E-opt: 0.2 (0.505), width: 16 Scan time: 4.560 The best scores are: opt bits E(85289) NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 p ( 114) 747 178.5 2.1e-45 NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 p ( 114) 599 144.5 3.4e-35 NP_001502 (OMIM: 155730) growth-regulated alpha pr ( 107) 287 72.9 1.2e-13 NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 p ( 107) 269 68.8 2e-12 NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 p ( 107) 263 67.4 5.3e-12 NP_002695 (OMIM: 121010) platelet basic protein pr ( 128) 251 64.7 4.1e-11 NP_002610 (OMIM: 173460) platelet factor 4 precurs ( 101) 245 63.3 8.9e-11 XP_005265753 (OMIM: 173460) PREDICTED: platelet fa ( 110) 236 61.2 4e-10 NP_002611 (OMIM: 173461) platelet factor 4 variant ( 104) 221 57.8 4.1e-09 NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 196 52.0 2.1e-07 NP_001556 (OMIM: 147310) C-X-C motif chemokine 10 ( 98) 186 49.7 1e-06 NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 p ( 125) 173 46.8 9.8e-06 NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 166 45.2 2.7e-05 XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 166 45.2 2.7e-05 NP_001029058 (OMIM: 600835,609423) stromal cell-de ( 119) 142 39.7 0.0013 NP_954637 (OMIM: 600835,609423) stromal cell-deriv ( 89) 131 37.1 0.0061 NP_000600 (OMIM: 600835,609423) stromal cell-deriv ( 93) 131 37.1 0.0063 NP_001171605 (OMIM: 600835,609423) stromal cell-de ( 140) 132 37.5 0.0072 >>NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 precu (114 aa) initn: 747 init1: 747 opt: 747 Z-score: 936.3 bits: 178.5 E(85289): 2.1e-45 Smith-Waterman score: 747; 100.0% identity (100.0% similar) in 114 aa overlap (1-114:1-114) 10 20 30 40 50 60 pF1KB6 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN 70 80 90 100 110 >>NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 precu (114 aa) initn: 645 init1: 599 opt: 599 Z-score: 752.8 bits: 144.5 E(85289): 3.4e-35 Smith-Waterman score: 599; 79.8% identity (93.0% similar) in 114 aa overlap (1-114:1-114) 10 20 30 40 50 60 pF1KB6 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP ::: :::::::::::.::::::.:::::: :::.:::::..::: ::::.::..: :.: NP_002 MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQGVHP 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN : :..:::: :::::::::::::::::..::::::::::::::::::.:::.: NP_002 KMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN 70 80 90 100 110 >>NP_001502 (OMIM: 155730) growth-regulated alpha protei (107 aa) initn: 296 init1: 249 opt: 287 Z-score: 366.2 bits: 72.9 E(85289): 1.2e-13 Smith-Waterman score: 287; 43.1% identity (75.2% similar) in 109 aa overlap (6-114:2-107) 10 20 30 40 50 60 pF1KB6 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP .::: .::. .:::::: . .:: ..: ::::: ::.. ..: NP_001 MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAG--ASVATELRCQCLQTLQGIHP 10 20 30 40 50 70 80 90 100 110 pF1KB6 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN :.: ...: ::.:...::.:.::::...::.: .:..::.:.:.:.: .:.: NP_001 KNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNS-DKSN 60 70 80 90 100 >>NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 precu (107 aa) initn: 288 init1: 245 opt: 269 Z-score: 343.9 bits: 68.8 E(85289): 2e-12 Smith-Waterman score: 269; 42.9% identity (76.5% similar) in 98 aa overlap (14-111:10-105) 10 20 30 40 50 60 pF1KB6 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP ::. .:::::: . .:: ..:.::::: ::.. .. NP_002 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAG--ASVVTELRCQCLQTLQGIHL 10 20 30 40 50 70 80 90 100 110 pF1KB6 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN :.: ...: ::.:...::.:.:::::..::.: .:...:.:.:::..:. NP_002 KNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN 60 70 80 90 100 >>NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 precu (107 aa) initn: 287 init1: 232 opt: 263 Z-score: 336.5 bits: 67.4 E(85289): 5.3e-12 Smith-Waterman score: 263; 40.4% identity (72.5% similar) in 109 aa overlap (6-114:2-107) 10 20 30 40 50 60 pF1KB6 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP .::. .::. .:::::: . .:: . . ::::: ::.. .. NP_002 MARATLSAAPSNPRLLRVALLLLLLVAASRRAAG--APLATELRCQCLQTLQGIHL 10 20 30 40 50 70 80 90 100 110 pF1KB6 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN :.: ...: ::.:...::.:.::::...::.: .:..::.:.:.: .: :.: NP_002 KNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNG-KSN 60 70 80 90 100 >>NP_002695 (OMIM: 121010) platelet basic protein prepro (128 aa) initn: 297 init1: 248 opt: 251 Z-score: 320.6 bits: 64.7 E(85289): 4.1e-11 Smith-Waterman score: 256; 40.5% identity (65.3% similar) in 121 aa overlap (2-107:7-121) 10 20 30 40 pF1KB6 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASA--GPV------------- . :: .:: : .: .:: : :::: :::. : . NP_002 MSLRLDTTPSCNSAR---PLHALQVLLLLSLLLTA---LASSTKGQTKRNLAKGKEESLD 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 SAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLK : . .:::: :...: ..::.: .:.:. : .:..:::.:.::.:...::::.:: .: NP_002 SDLYAELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIK 60 70 80 90 100 110 110 pF1KB6 KVIQKILDSGNKKN :..:: : NP_002 KIVQKKLAGDESAD 120 >>NP_002610 (OMIM: 173460) platelet factor 4 precursor [ (101 aa) initn: 227 init1: 166 opt: 245 Z-score: 314.5 bits: 63.3 E(85289): 8.9e-11 Smith-Waterman score: 245; 40.4% identity (72.7% similar) in 99 aa overlap (15-109:4-101) 10 20 30 40 50 pF1KB6 MSLPSSRAARVPGPSGSLCA----LLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTL ....:: :: : ::: : .: :. . .:.: :...: NP_002 MSSAAGFCASRPGLLFLGLLLLPL-VVAFASAEAEEDGDLQCLCVKTTS 10 20 30 40 60 70 80 90 100 110 pF1KB6 RVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN .: :. : .:.:. :::.: ....:.::::...::: .::. ::.:.:.:.: NP_002 QVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES 50 60 70 80 90 100 >>XP_005265753 (OMIM: 173460) PREDICTED: platelet factor (110 aa) initn: 212 init1: 166 opt: 236 Z-score: 302.8 bits: 61.2 E(85289): 4e-10 Smith-Waterman score: 236; 35.8% identity (68.9% similar) in 106 aa overlap (4-109:10-110) 10 20 30 40 50 pF1KB6 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRV :. : ::: . . . : : :. : . . . .. .:.: :... XP_005 MITATLNGEPAECLATVPGAAPAPPTWLEQL--LSGGGVIYAEAEEDG---DLQCLCVKT 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 TLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN : .: :. : .:.:. :::.: ....:.::::...::: .::. ::.:.:.:.: XP_005 TSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES 60 70 80 90 100 110 >>NP_002611 (OMIM: 173461) platelet factor 4 variant pre (104 aa) initn: 199 init1: 141 opt: 221 Z-score: 284.6 bits: 57.8 E(85289): 4.1e-09 Smith-Waterman score: 221; 37.5% identity (66.3% similar) in 104 aa overlap (6-109:2-104) 10 20 30 40 50 60 pF1KB6 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP : ::: .. .: : ::: : .: : . .:.: :...: .: : NP_002 MSSAARSRLTRATRQEMLFLALLLLPV-VVAFARAEAEEDGDLQCLCVKTTSQVRP 10 20 30 40 50 70 80 90 100 110 pF1KB6 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN . : .:.:. :::.: ....:.::::...::: .: . ::.:.. :.: NP_002 RHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES 60 70 80 90 100 >>NP_000575 (OMIM: 146930) interleukin-8 precursor [Homo (99 aa) initn: 206 init1: 160 opt: 196 Z-score: 253.8 bits: 52.0 E(85289): 2.1e-07 Smith-Waterman score: 196; 37.1% identity (80.0% similar) in 70 aa overlap (39-107:26-93) 10 20 30 40 50 60 pF1KB6 ARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLR-VNPKTIGKLQ : :: :::: :... . .:: : .:. NP_000 MTSKLAVALLAAFLISAALCEGAVLPRSA--KELRCQCIKTYSKPFHPKFIKELR 10 20 30 40 50 70 80 90 100 110 pF1KB6 VFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN :. .::.:...:....:..:...::::. ....:..:.: NP_000 VIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS 60 70 80 90 114 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:52:57 2016 done: Fri Nov 4 23:52:58 2016 Total Scan time: 4.560 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]