FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6766, 148 aa 1>>>pF1KB6766 148 - 148 aa - 148 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7197+/-0.000246; mu= 10.7256+/- 0.015 mean_var=75.5667+/-14.684, 0's: 0 Z-trim(122.4): 17 B-trim: 0 in 0/59 Lambda= 0.147540 statistics sampled from 40376 (40394) to 40376 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.474), width: 16 Scan time: 4.910 The best scores are: opt bits E(85289) NP_002082 (OMIM: 137260) gastrin-releasing peptide ( 148) 1004 221.7 3.5e-58 NP_001012530 (OMIM: 137260) gastrin-releasing pept ( 141) 935 207.0 8.8e-54 XP_016881201 (OMIM: 137260) PREDICTED: gastrin-rel ( 142) 861 191.2 4.9e-49 NP_001012531 (OMIM: 137260) gastrin-releasing pept ( 138) 824 183.3 1.1e-46 XP_016881202 (OMIM: 137260) PREDICTED: gastrin-rel ( 129) 823 183.1 1.2e-46 XP_016881203 (OMIM: 137260) PREDICTED: gastrin-rel ( 117) 690 154.8 3.8e-38 XP_011524235 (OMIM: 137260) PREDICTED: gastrin-rel ( 125) 687 154.2 6.2e-38 >>NP_002082 (OMIM: 137260) gastrin-releasing peptide iso (148 aa) initn: 1004 init1: 1004 opt: 1004 Z-score: 1165.6 bits: 221.7 E(85289): 3.5e-58 Smith-Waterman score: 1004; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB6 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK 70 80 90 100 110 120 130 140 pF1KB6 DVGSKGKVGRLSAPGSQREGRNPQLNQQ :::::::::::::::::::::::::::: NP_002 DVGSKGKVGRLSAPGSQREGRNPQLNQQ 130 140 >>NP_001012530 (OMIM: 137260) gastrin-releasing peptide (141 aa) initn: 945 init1: 861 opt: 935 Z-score: 1086.5 bits: 207.0 E(85289): 8.8e-54 Smith-Waterman score: 935; 95.3% identity (95.3% similar) in 148 aa overlap (1-148:1-141) 10 20 30 40 50 60 pF1KB6 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK 70 80 90 100 110 120 130 140 pF1KB6 DVGSKGKVGRLSAPGSQREGRNPQLNQQ ::::::: :::::::::::::: NP_001 DVGSKGK-------GSQREGRNPQLNQQ 130 140 >>XP_016881201 (OMIM: 137260) PREDICTED: gastrin-releasi (142 aa) initn: 861 init1: 861 opt: 861 Z-score: 1001.3 bits: 191.2 E(85289): 4.9e-49 Smith-Waterman score: 861; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB6 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK 70 80 90 100 110 120 130 140 pF1KB6 DVGSKGKVGRLSAPGSQREGRNPQLNQQ ::::::: XP_016 DVGSKGKDSLLQVLNVKEGTPS 130 140 >>NP_001012531 (OMIM: 137260) gastrin-releasing peptide (138 aa) initn: 859 init1: 824 opt: 824 Z-score: 959.0 bits: 183.3 E(85289): 1.1e-46 Smith-Waterman score: 824; 99.2% identity (100.0% similar) in 122 aa overlap (1-122:1-122) 10 20 30 40 50 60 pF1KB6 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK 70 80 90 100 110 120 130 140 pF1KB6 DVGSKGKVGRLSAPGSQREGRNPQLNQQ :. NP_001 DLVDSLLQVLNVKEGTPS 130 >>XP_016881202 (OMIM: 137260) PREDICTED: gastrin-releasi (129 aa) initn: 823 init1: 823 opt: 823 Z-score: 958.3 bits: 183.1 E(85289): 1.2e-46 Smith-Waterman score: 823; 100.0% identity (100.0% similar) in 121 aa overlap (1-121:1-121) 10 20 30 40 50 60 pF1KB6 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFK 70 80 90 100 110 120 130 140 pF1KB6 DVGSKGKVGRLSAPGSQREGRNPQLNQQ : XP_016 DTLCSRFST >>XP_016881203 (OMIM: 137260) PREDICTED: gastrin-releasi (117 aa) initn: 688 init1: 688 opt: 690 Z-score: 805.9 bits: 154.8 E(85289): 3.8e-38 Smith-Waterman score: 690; 89.7% identity (94.0% similar) in 117 aa overlap (33-148:1-117) 10 20 30 40 50 60 pF1KB6 GRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNH-WAVGHLMGKKSTGESSSV .: .: . : . .::::::::::::::: XP_016 MLLSMRMLSAHIYRLGHLMGKKSTGESSSV 10 20 30 70 80 90 100 110 120 pF1KB6 SERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKD 40 50 60 70 80 90 130 140 pF1KB6 VGSKGKVGRLSAPGSQREGRNPQLNQQ ::::::::::::::::::::::::::: XP_016 VGSKGKVGRLSAPGSQREGRNPQLNQQ 100 110 >>XP_011524235 (OMIM: 137260) PREDICTED: gastrin-releasi (125 aa) initn: 687 init1: 687 opt: 687 Z-score: 802.0 bits: 154.2 E(85289): 6.2e-38 Smith-Waterman score: 687; 100.0% identity (100.0% similar) in 102 aa overlap (47-148:24-125) 20 30 40 50 60 70 pF1KB6 LAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSSVSERGSLKQQLREYIR :::::::::::::::::::::::::::::: XP_011 MLVKRASYLLSCHTSGQSCLGIPGHLMGKKSTGESSSVSERGSLKQQLREYIR 10 20 30 40 50 80 90 100 110 120 130 pF1KB6 WEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKDVGSKGKVGRLSAPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKDVGSKGKVGRLSAPGS 60 70 80 90 100 110 140 pF1KB6 QREGRNPQLNQQ :::::::::::: XP_011 QREGRNPQLNQQ 120 148 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:17:32 2016 done: Fri Nov 4 15:17:33 2016 Total Scan time: 4.910 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]