FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6768, 148 aa 1>>>pF1KB6768 148 - 148 aa - 148 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3287+/-0.000767; mu= 11.9712+/- 0.046 mean_var=77.4053+/-15.014, 0's: 0 Z-trim(110.0): 26 B-trim: 8 in 1/52 Lambda= 0.145777 statistics sampled from 11274 (11291) to 11274 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.347), width: 16 Scan time: 1.680 The best scores are: opt bits E(32554) CCDS9195.1 PLA2G1B gene_id:5319|Hs108|chr12 ( 148) 1057 231.0 2.1e-61 CCDS201.1 PLA2G2A gene_id:5320|Hs108|chr1 ( 144) 338 79.7 6.9e-16 CCDS203.1 PLA2G2D gene_id:26279|Hs108|chr1 ( 145) 325 77.0 4.6e-15 CCDS10555.1 PLA2G10 gene_id:8399|Hs108|chr16 ( 165) 314 74.7 2.5e-14 CCDS200.1 PLA2G2E gene_id:30814|Hs108|chr1 ( 142) 308 73.4 5.4e-14 CCDS204.2 PLA2G2F gene_id:64600|Hs108|chr1 ( 211) 304 72.7 1.3e-13 CCDS47919.1 OC90 gene_id:729330|Hs108|chr8 ( 477) 269 65.6 4.1e-11 CCDS202.1 PLA2G5 gene_id:5322|Hs108|chr1 ( 138) 262 63.7 4.3e-11 >>CCDS9195.1 PLA2G1B gene_id:5319|Hs108|chr12 (148 aa) initn: 1057 init1: 1057 opt: 1057 Z-score: 1215.8 bits: 231.0 E(32554): 2.1e-61 Smith-Waterman score: 1057; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS91 DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC 70 80 90 100 110 120 130 140 pF1KB6 DRNAAICFSKAPYNKAHKNLDTKKYCQS :::::::::::::::::::::::::::: CCDS91 DRNAAICFSKAPYNKAHKNLDTKKYCQS 130 140 >>CCDS201.1 PLA2G2A gene_id:5320|Hs108|chr1 (144 aa) initn: 316 init1: 197 opt: 338 Z-score: 398.7 bits: 79.7 E(32554): 6.9e-16 Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138) 10 20 30 40 50 pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP :: ::.:::.. . .. . . .:..::: . :.. : :. :::.::.:: :.: CCDS20 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI : :.:: ::: :: . .: .: ::: .:..: ::: :::. :. :.. . CCDS20 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL 60 70 80 90 100 120 130 140 pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS :.::. :: ::. :. ::: .. ..:.:. CCDS20 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC 110 120 130 140 >>CCDS203.1 PLA2G2D gene_id:26279|Hs108|chr1 (145 aa) initn: 312 init1: 185 opt: 325 Z-score: 383.9 bits: 77.0 E(32554): 4.6e-15 Smith-Waterman score: 325; 40.2% identity (64.4% similar) in 132 aa overlap (1-130:1-121) 10 20 30 40 50 pF1KB6 MKLLVLAVLLTVAAADSGISP--RAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGT :.: .: :...: :. : .. .. ::.: : :. :.: : :::.::::: : CCDS20 MELALLCGLVVMA----GVIPIQGGILNLNKMVKQVT-GKMPILSYWPYGCHCGLGGRGQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFIC : : : :::::: :::. : ..:.. : : :. : . : ::.:.. :: .: CCDS20 PKDATDWCCQTHDCCYDHLKT-QGCSI-----YKDYYRYNFSQGNIHCSDKGSWCEQQLC 60 70 80 90 100 120 130 140 pF1KB6 NCDRNAAICFSKAPYNKAHKNLDTKKYCQS ::...:.:... CCDS20 ACDKEVAFCLKRNLDTYQKRLRFYWRPHCRGQTPGC 110 120 130 140 >>CCDS10555.1 PLA2G10 gene_id:8399|Hs108|chr16 (165 aa) initn: 312 init1: 171 opt: 314 Z-score: 370.6 bits: 74.7 E(32554): 2.5e-14 Smith-Waterman score: 314; 35.4% identity (68.1% similar) in 113 aa overlap (22-134:42-146) 10 20 30 40 50 pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYC :.. .. . :: : . : . : .:::.: CCDS10 LLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRT-P-IAYMKYGCFC 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 GLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNK :::: : : : .: ::. :: :: .:.. .: .: :. ::..: .... :. .. CCDS10 GLGGHGQPRDAIDWCCHGHDCCYTRAEEA-GC-----SPKTERYSWQCVNQSVLCGPAEN 70 80 90 100 110 120 120 130 140 pF1KB6 ECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS .:. ..:.::.. : :.... :: CCDS10 KCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD 130 140 150 160 >>CCDS200.1 PLA2G2E gene_id:30814|Hs108|chr1 (142 aa) initn: 258 init1: 202 opt: 308 Z-score: 364.7 bits: 73.4 E(32554): 5.4e-14 Smith-Waterman score: 308; 39.2% identity (64.2% similar) in 120 aa overlap (26-143:23-133) 10 20 30 40 50 60 pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV :: ::. . : :.::.::::::.::: :: CCDS20 MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSA--LQYNDYGCYCGIGGSHWPV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC :. : ::..:: :: . .:: .:. : . : .: : .: :.... :. . :.: CCDS20 DQTDWCCHAHDCCYGRLEKL-GCE-----PKLEKYLFSVSERGIFCAGRTT-CQRLTCEC 60 70 80 90 100 130 140 pF1KB6 DRNAAICFSK--APYNKAHKNLDTKKYCQS :. ::.:: . . ::. . . .: CCDS20 DKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC 110 120 130 140 >>CCDS204.2 PLA2G2F gene_id:64600|Hs108|chr1 (211 aa) initn: 290 init1: 178 opt: 304 Z-score: 357.8 bits: 72.7 E(32554): 1.3e-13 Smith-Waterman score: 304; 34.5% identity (64.2% similar) in 148 aa overlap (2-147:46-182) 10 20 30 pF1KB6 MKLLVLAVLL-TVAAADSGISPRAVWQFRKM :....:.: .: .. : .. ... : CCDS20 VLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHG----SLLNLKAM 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 IKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNP .. : : . .: . .::::::::: : : ::.: ::..:: :: : ..:. .:. CCDS20 VEAVT-GRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCY-QELFDQGCHPYVDH- 80 90 100 110 120 100 110 120 130 140 pF1KB6 YTHTYSYSCSGSAITCSSKNK-ECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS : :: ... :.::. :: ::. : ::.: ..:. . : . .... . ::: CCDS20 YDHTIE---NNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGF-LNVYCQGP 130 140 150 160 170 180 CCDS20 TPNCSIYEPPPEEVTCSHQSPAPPAPP 190 200 210 >>CCDS47919.1 OC90 gene_id:729330|Hs108|chr8 (477 aa) initn: 397 init1: 165 opt: 269 Z-score: 313.0 bits: 65.6 E(32554): 4.1e-11 Smith-Waterman score: 286; 36.4% identity (63.6% similar) in 121 aa overlap (26-146:78-190) 10 20 30 40 50 pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGG :: . .::: : : ....::: : . CCDS47 NVESVAEIFDCLGPHFTWLQAVFTNFPVLIQFVNGMKCVA-GLCPR-DFEDYGCTCRFEM 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB6 SGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEA : :::: :.:: : ::..: ..: : :..: . .: .. : : ::.. :: CCDS47 EGLPVDESDSCCFQHRRCYEEAAEMD-C---LQDPAKLSTEVNCVSKKIICESKDN-CEH 110 120 130 140 150 160 120 130 140 pF1KB6 FICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS ..:.::. : :.... :.. . :::. .: CCDS47 LLCTCDKAAIECLARSSLNSSLNLLDTS-FCLAQTPETTIKEDLTTLLPRVVPVEPTDTS 170 180 190 200 210 CCDS47 LTALSGEEAGHDQEGVGAARATSPPGSAEIVATRVTAKIVTLVPAGIKSLGLAVSSVEND 220 230 240 250 260 270 >-- initn: 397 init1: 165 opt: 269 Z-score: 313.0 bits: 65.6 E(32554): 4.1e-11 Smith-Waterman score: 269; 33.3% identity (65.9% similar) in 123 aa overlap (17-139:298-412) 10 20 30 40 pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNN :: . ... :. .:. : . . : :... CCDS47 SLGLAVSSVENDPEETTEKACDRFTFLHLGSGDNMQVMPQLGEMLFC-LTSRCPE-EFES 270 280 290 300 310 320 50 60 70 80 90 100 pF1KB6 YGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITC :::::: : : : :.::.:: .: : .:...: .: .: :.. . : . : CCDS47 YGCYCGQEGRGEPRDDLDRCCLSHHCCLEQVRRL-GC-LLERLPWSPVV---CVDHTPKC 330 340 350 360 370 380 110 120 130 140 pF1KB6 SSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS .... :: ..: ::..:: :...: .:.. :. CCDS47 GGQSL-CEKLLCACDQTAAECMTSASFNQSLKSPSRLGCPGQPAACEDSLHPVPAAPTLG 390 400 410 420 430 CCDS47 SSSEEDSEEDPPQEDLGRAKRFLRKSLGPLGIGPLHGR 440 450 460 470 >>CCDS202.1 PLA2G5 gene_id:5322|Hs108|chr1 (138 aa) initn: 209 init1: 181 opt: 262 Z-score: 312.6 bits: 63.7 E(32554): 4.3e-11 Smith-Waterman score: 262; 34.3% identity (62.2% similar) in 143 aa overlap (1-138:1-130) 10 20 30 40 50 pF1KB6 MK-LLVLAVLL--TVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSG :: :: :: .: .: :...:. ....::. : :.. . .:. :::::: :: : CCDS20 MKGLLPLAWFLACSVPAVQGGL-----LDLKSMIEKVT-GKNALTNYGFYGCYCGWGGRG 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 TPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI :: : : :: .::.:: . .. .: : :..:.: . ...:: . :.. . CCDS20 TPKDGTDWCCWAHDHCYGRLEE-KGC-----NIRTQSYKYRFAWGVVTCEP-GPFCHVNL 60 70 80 90 100 120 130 140 pF1KB6 CNCDRNAAICFSKA--PYNKAHKNLDTKKYCQS : :::. . :... :: .. CCDS20 CACDRKLVYCLKRNLRSYNPQYQYFPNILCS 110 120 130 148 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:54:03 2016 done: Fri Nov 4 23:54:04 2016 Total Scan time: 1.680 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]