Result of FASTA (omim) for
pF1KB6768
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6768, 148 aa
1>>>pF1KB6768 148 - 148 aa - 148 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3307+/-0.000338; mu= 11.9319+/- 0.021
mean_var=75.1877+/-15.184, 0's: 0 Z-trim(116.4): 32 B-trim: 901 in 1/54
Lambda= 0.147911
statistics sampled from 27552 (27586) to 27552 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.323), width: 16
Scan time: 4.970
The best scores are: opt bits E(85289)
NP_000919 (OMIM: 172410) phospholipase A2 precurso ( 148) 1057 234.2 5.9e-62
NP_001155201 (OMIM: 172411) phospholipase A2, memb ( 144) 338 80.8 8.8e-16
NP_000291 (OMIM: 172411) phospholipase A2, membran ( 144) 338 80.8 8.8e-16
NP_001155199 (OMIM: 172411) phospholipase A2, memb ( 144) 338 80.8 8.8e-16
NP_001155200 (OMIM: 172411) phospholipase A2, memb ( 144) 338 80.8 8.8e-16
NP_036532 (OMIM: 605630) group IID secretory phosp ( 145) 325 78.0 6.1e-15
NP_003552 (OMIM: 603603) group 10 secretory phosph ( 165) 314 75.7 3.4e-14
XP_011540258 (OMIM: 616793) PREDICTED: group IIF s ( 211) 304 73.6 1.8e-13
NP_073730 (OMIM: 616793) group IIF secretory phosp ( 211) 304 73.6 1.8e-13
NP_001073868 (OMIM: 601658) otoconin-90 precursor ( 477) 269 66.4 6.1e-11
XP_011539890 (OMIM: 228980,601192) PREDICTED: calc ( 138) 262 64.5 6.5e-11
XP_011539893 (OMIM: 228980,601192) PREDICTED: calc ( 138) 262 64.5 6.5e-11
XP_005245950 (OMIM: 228980,601192) PREDICTED: calc ( 138) 262 64.5 6.5e-11
NP_000920 (OMIM: 228980,601192) calcium-dependent ( 138) 262 64.5 6.5e-11
XP_011539889 (OMIM: 228980,601192) PREDICTED: calc ( 138) 262 64.5 6.5e-11
XP_011539894 (OMIM: 228980,601192) PREDICTED: calc ( 138) 262 64.5 6.5e-11
XP_011539891 (OMIM: 228980,601192) PREDICTED: calc ( 138) 262 64.5 6.5e-11
XP_011539892 (OMIM: 228980,601192) PREDICTED: calc ( 138) 262 64.5 6.5e-11
XP_005245949 (OMIM: 228980,601192) PREDICTED: calc ( 169) 262 64.6 7.6e-11
XP_011539888 (OMIM: 228980,601192) PREDICTED: calc ( 169) 262 64.6 7.6e-11
XP_005245948 (OMIM: 228980,601192) PREDICTED: calc ( 169) 262 64.6 7.6e-11
XP_011520997 (OMIM: 603603) PREDICTED: group 10 se ( 133) 238 59.4 2.2e-09
XP_011521000 (OMIM: 603603) PREDICTED: group 10 se ( 120) 231 57.9 5.7e-09
XP_011520999 (OMIM: 603603) PREDICTED: group 10 se ( 124) 231 57.9 5.9e-09
XP_011520998 (OMIM: 603603) PREDICTED: group 10 se ( 131) 231 57.9 6.1e-09
XP_011540257 (OMIM: 616793) PREDICTED: group IIF s ( 219) 214 54.4 1.1e-07
NP_001258743 (OMIM: 605630) group IID secretory ph ( 62) 143 38.9 0.0015
>>NP_000919 (OMIM: 172410) phospholipase A2 precursor [H (148 aa)
initn: 1057 init1: 1057 opt: 1057 Z-score: 1233.3 bits: 234.2 E(85289): 5.9e-62
Smith-Waterman score: 1057; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148)
10 20 30 40 50 60
pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
70 80 90 100 110 120
130 140
pF1KB6 DRNAAICFSKAPYNKAHKNLDTKKYCQS
::::::::::::::::::::::::::::
NP_000 DRNAAICFSKAPYNKAHKNLDTKKYCQS
130 140
>>NP_001155201 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 316 init1: 197 opt: 338 Z-score: 404.3 bits: 80.8 E(85289): 8.8e-16
Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138)
10 20 30 40 50
pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP
:: ::.:::.. . .. . . .:..::: . :.. : :. :::.::.:: :.:
NP_001 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI
: :.:: ::: :: . .: .: ::: .:..: ::: :::. :. :.. .
NP_001 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL
60 70 80 90 100
120 130 140
pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS
:.::. :: ::. :. ::: .. ..:.:.
NP_001 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC
110 120 130 140
>>NP_000291 (OMIM: 172411) phospholipase A2, membrane as (144 aa)
initn: 316 init1: 197 opt: 338 Z-score: 404.3 bits: 80.8 E(85289): 8.8e-16
Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138)
10 20 30 40 50
pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP
:: ::.:::.. . .. . . .:..::: . :.. : :. :::.::.:: :.:
NP_000 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI
: :.:: ::: :: . .: .: ::: .:..: ::: :::. :. :.. .
NP_000 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL
60 70 80 90 100
120 130 140
pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS
:.::. :: ::. :. ::: .. ..:.:.
NP_000 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC
110 120 130 140
>>NP_001155199 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 316 init1: 197 opt: 338 Z-score: 404.3 bits: 80.8 E(85289): 8.8e-16
Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138)
10 20 30 40 50
pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP
:: ::.:::.. . .. . . .:..::: . :.. : :. :::.::.:: :.:
NP_001 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI
: :.:: ::: :: . .: .: ::: .:..: ::: :::. :. :.. .
NP_001 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL
60 70 80 90 100
120 130 140
pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS
:.::. :: ::. :. ::: .. ..:.:.
NP_001 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC
110 120 130 140
>>NP_001155200 (OMIM: 172411) phospholipase A2, membrane (144 aa)
initn: 316 init1: 197 opt: 338 Z-score: 404.3 bits: 80.8 E(85289): 8.8e-16
Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138)
10 20 30 40 50
pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP
:: ::.:::.. . .. . . .:..::: . :.. : :. :::.::.:: :.:
NP_001 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI
: :.:: ::: :: . .: .: ::: .:..: ::: :::. :. :.. .
NP_001 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL
60 70 80 90 100
120 130 140
pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS
:.::. :: ::. :. ::: .. ..:.:.
NP_001 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC
110 120 130 140
>>NP_036532 (OMIM: 605630) group IID secretory phospholi (145 aa)
initn: 312 init1: 185 opt: 325 Z-score: 389.3 bits: 78.0 E(85289): 6.1e-15
Smith-Waterman score: 325; 40.2% identity (64.4% similar) in 132 aa overlap (1-130:1-121)
10 20 30 40 50
pF1KB6 MKLLVLAVLLTVAAADSGISP--RAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGT
:.: .: :...: :. : .. .. ::.: : :. :.: : :::.::::: :
NP_036 MELALLCGLVVMA----GVIPIQGGILNLNKMVKQVT-GKMPILSYWPYGCHCGLGGRGQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 PVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFIC
: : : :::::: :::. : ..:.. : : :. : . : ::.:.. :: .:
NP_036 PKDATDWCCQTHDCCYDHLKT-QGCSI-----YKDYYRYNFSQGNIHCSDKGSWCEQQLC
60 70 80 90 100
120 130 140
pF1KB6 NCDRNAAICFSKAPYNKAHKNLDTKKYCQS
::...:.:...
NP_036 ACDKEVAFCLKRNLDTYQKRLRFYWRPHCRGQTPGC
110 120 130 140
>>NP_003552 (OMIM: 603603) group 10 secretory phospholip (165 aa)
initn: 312 init1: 171 opt: 314 Z-score: 375.8 bits: 75.7 E(85289): 3.4e-14
Smith-Waterman score: 314; 35.4% identity (68.1% similar) in 113 aa overlap (22-134:42-146)
10 20 30 40 50
pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYC
:.. .. . :: : . : . : .:::.:
NP_003 LLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRT-P-IAYMKYGCFC
20 30 40 50 60
60 70 80 90 100 110
pF1KB6 GLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNK
:::: : : : .: ::. :: :: .:.. .: .: :. ::..: .... :. ..
NP_003 GLGGHGQPRDAIDWCCHGHDCCYTRAEEA-GC-----SPKTERYSWQCVNQSVLCGPAEN
70 80 90 100 110 120
120 130 140
pF1KB6 ECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
.:. ..:.::.. : :.... ::
NP_003 KCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
130 140 150 160
>>XP_011540258 (OMIM: 616793) PREDICTED: group IIF secre (211 aa)
initn: 290 init1: 178 opt: 304 Z-score: 362.7 bits: 73.6 E(85289): 1.8e-13
Smith-Waterman score: 304; 34.5% identity (64.2% similar) in 148 aa overlap (2-147:46-182)
10 20 30
pF1KB6 MKLLVLAVLL-TVAAADSGISPRAVWQFRKM
:....:.: .: .. : .. ... :
XP_011 VLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHG----SLLNLKAM
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB6 IKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNP
.. : : . .: . .::::::::: : : ::.: ::..:: :: : ..:. .:.
XP_011 VEAVT-GRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCY-QELFDQGCHPYVDH-
80 90 100 110 120
100 110 120 130 140
pF1KB6 YTHTYSYSCSGSAITCSSKNK-ECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
: :: ... :.::. :: ::. : ::.: ..:. . : . .... . :::
XP_011 YDHTIE---NNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGF-LNVYCQGP
130 140 150 160 170 180
XP_011 TPNCSIYEPPPEEVTCSHQSPAPPAPP
190 200 210
>>NP_073730 (OMIM: 616793) group IIF secretory phospholi (211 aa)
initn: 290 init1: 178 opt: 304 Z-score: 362.7 bits: 73.6 E(85289): 1.8e-13
Smith-Waterman score: 304; 34.5% identity (64.2% similar) in 148 aa overlap (2-147:46-182)
10 20 30
pF1KB6 MKLLVLAVLL-TVAAADSGISPRAVWQFRKM
:....:.: .: .. : .. ... :
NP_073 VLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHG----SLLNLKAM
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB6 IKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNP
.. : : . .: . .::::::::: : : ::.: ::..:: :: : ..:. .:.
NP_073 VEAVT-GRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCY-QELFDQGCHPYVDH-
80 90 100 110 120
100 110 120 130 140
pF1KB6 YTHTYSYSCSGSAITCSSKNK-ECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
: :: ... :.::. :: ::. : ::.: ..:. . : . .... . :::
NP_073 YDHTIE---NNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGF-LNVYCQGP
130 140 150 160 170 180
NP_073 TPNCSIYEPPPEEVTCSHQSPAPPAPP
190 200 210
>>NP_001073868 (OMIM: 601658) otoconin-90 precursor [Hom (477 aa)
initn: 397 init1: 165 opt: 269 Z-score: 317.4 bits: 66.4 E(85289): 6.1e-11
Smith-Waterman score: 286; 36.4% identity (63.6% similar) in 121 aa overlap (26-146:78-190)
10 20 30 40 50
pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGG
:: . .::: : : ....::: : .
NP_001 NVESVAEIFDCLGPHFTWLQAVFTNFPVLIQFVNGMKCVA-GLCPR-DFEDYGCTCRFEM
50 60 70 80 90 100
60 70 80 90 100 110
pF1KB6 SGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEA
: :::: :.:: : ::..: ..: : :..: . .: .. : : ::.. ::
NP_001 EGLPVDESDSCCFQHRRCYEEAAEMD-C---LQDPAKLSTEVNCVSKKIICESKDN-CEH
110 120 130 140 150 160
120 130 140
pF1KB6 FICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
..:.::. : :.... :.. . :::. .:
NP_001 LLCTCDKAAIECLARSSLNSSLNLLDTS-FCLAQTPETTIKEDLTTLLPRVVPVEPTDTS
170 180 190 200 210
NP_001 LTALSGEEAGHDQEGVGAARATSPPGSAEIVATRVTAKIVTLVPAGIKSLGLAVSSVEND
220 230 240 250 260 270
>--
initn: 397 init1: 165 opt: 269 Z-score: 317.4 bits: 66.4 E(85289): 6.1e-11
Smith-Waterman score: 269; 33.3% identity (65.9% similar) in 123 aa overlap (17-139:298-412)
10 20 30 40
pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNN
:: . ... :. .:. : . . : :...
NP_001 SLGLAVSSVENDPEETTEKACDRFTFLHLGSGDNMQVMPQLGEMLFC-LTSRCPE-EFES
270 280 290 300 310 320
50 60 70 80 90 100
pF1KB6 YGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITC
:::::: : : : :.::.:: .: : .:...: .: .: :.. . : . :
NP_001 YGCYCGQEGRGEPRDDLDRCCLSHHCCLEQVRRL-GC-LLERLPWSPVV---CVDHTPKC
330 340 350 360 370 380
110 120 130 140
pF1KB6 SSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
.... :: ..: ::..:: :...: .:.. :.
NP_001 GGQSL-CEKLLCACDQTAAECMTSASFNQSLKSPSRLGCPGQPAACEDSLHPVPAAPTLG
390 400 410 420 430
NP_001 SSSEEDSEEDPPQEDLGRAKRFLRKSLGPLGIGPLHGR
440 450 460 470
148 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:54:04 2016 done: Fri Nov 4 23:54:05 2016
Total Scan time: 4.970 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]