FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6769, 116 aa 1>>>pF1KB6769 116 - 116 aa - 116 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9474+/-0.000244; mu= 13.3238+/- 0.015 mean_var=73.3892+/-15.001, 0's: 0 Z-trim(122.8): 15 B-trim: 430 in 1/50 Lambda= 0.149713 statistics sampled from 41394 (41419) to 41394 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.842), E-opt: 0.2 (0.486), width: 16 Scan time: 4.100 The best scores are: opt bits E(85289) XP_016862102 (OMIM: 601665,605353) PREDICTED: appe ( 116) 790 178.3 2.5e-45 NP_001289752 (OMIM: 601665,605353) appetite-regula ( 116) 790 178.3 2.5e-45 NP_001128413 (OMIM: 601665,605353) appetite-regula ( 116) 790 178.3 2.5e-45 NP_001289751 (OMIM: 601665,605353) appetite-regula ( 117) 778 175.7 1.5e-44 NP_001289750 (OMIM: 601665,605353) appetite-regula ( 117) 778 175.7 1.5e-44 NP_001289753 (OMIM: 601665,605353) appetite-regula ( 117) 778 175.7 1.5e-44 XP_016862101 (OMIM: 601665,605353) PREDICTED: appe ( 117) 778 175.7 1.5e-44 NP_057446 (OMIM: 601665,605353) appetite-regulatin ( 117) 778 175.7 1.5e-44 NP_001289754 (OMIM: 601665,605353) appetite-regula ( 117) 778 175.7 1.5e-44 NP_001128417 (OMIM: 601665,605353) appetite-regula ( 104) 567 130.1 7.3e-31 NP_001128416 (OMIM: 601665,605353) appetite-regula ( 105) 555 127.5 4.4e-30 NP_001128418 (OMIM: 601665,605353) appetite-regula ( 66) 290 70.1 5.3e-13 >>XP_016862102 (OMIM: 601665,605353) PREDICTED: appetite (116 aa) initn: 790 init1: 790 opt: 790 Z-score: 934.8 bits: 178.3 E(85289): 2.5e-45 Smith-Waterman score: 790; 100.0% identity (100.0% similar) in 116 aa overlap (1-116:1-116) 10 20 30 40 50 60 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQRKESKKPPAKLQPRALAGWLRPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQRKESKKPPAKLQPRALAGWLRPED 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>NP_001289752 (OMIM: 601665,605353) appetite-regulating (116 aa) initn: 790 init1: 790 opt: 790 Z-score: 934.8 bits: 178.3 E(85289): 2.5e-45 Smith-Waterman score: 790; 100.0% identity (100.0% similar) in 116 aa overlap (1-116:1-116) 10 20 30 40 50 60 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQRKESKKPPAKLQPRALAGWLRPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQRKESKKPPAKLQPRALAGWLRPED 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>NP_001128413 (OMIM: 601665,605353) appetite-regulating (116 aa) initn: 790 init1: 790 opt: 790 Z-score: 934.8 bits: 178.3 E(85289): 2.5e-45 Smith-Waterman score: 790; 100.0% identity (100.0% similar) in 116 aa overlap (1-116:1-116) 10 20 30 40 50 60 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQRKESKKPPAKLQPRALAGWLRPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQRKESKKPPAKLQPRALAGWLRPED 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>NP_001289751 (OMIM: 601665,605353) appetite-regulating (117 aa) initn: 551 init1: 551 opt: 778 Z-score: 920.7 bits: 175.7 E(85289): 1.5e-44 Smith-Waterman score: 778; 99.1% identity (99.1% similar) in 117 aa overlap (1-116:1-117) 10 20 30 40 50 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQ-RKESKKPPAKLQPRALAGWLRPE :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_001 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>NP_001289750 (OMIM: 601665,605353) appetite-regulating (117 aa) initn: 551 init1: 551 opt: 778 Z-score: 920.7 bits: 175.7 E(85289): 1.5e-44 Smith-Waterman score: 778; 99.1% identity (99.1% similar) in 117 aa overlap (1-116:1-117) 10 20 30 40 50 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQ-RKESKKPPAKLQPRALAGWLRPE :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_001 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>NP_001289753 (OMIM: 601665,605353) appetite-regulating (117 aa) initn: 551 init1: 551 opt: 778 Z-score: 920.7 bits: 175.7 E(85289): 1.5e-44 Smith-Waterman score: 778; 99.1% identity (99.1% similar) in 117 aa overlap (1-116:1-117) 10 20 30 40 50 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQ-RKESKKPPAKLQPRALAGWLRPE :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_001 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>XP_016862101 (OMIM: 601665,605353) PREDICTED: appetite (117 aa) initn: 551 init1: 551 opt: 778 Z-score: 920.7 bits: 175.7 E(85289): 1.5e-44 Smith-Waterman score: 778; 99.1% identity (99.1% similar) in 117 aa overlap (1-116:1-117) 10 20 30 40 50 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQ-RKESKKPPAKLQPRALAGWLRPE :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>NP_057446 (OMIM: 601665,605353) appetite-regulating ho (117 aa) initn: 551 init1: 551 opt: 778 Z-score: 920.7 bits: 175.7 E(85289): 1.5e-44 Smith-Waterman score: 778; 99.1% identity (99.1% similar) in 117 aa overlap (1-116:1-117) 10 20 30 40 50 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQ-RKESKKPPAKLQPRALAGWLRPE :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_057 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>NP_001289754 (OMIM: 601665,605353) appetite-regulating (117 aa) initn: 551 init1: 551 opt: 778 Z-score: 920.7 bits: 175.7 E(85289): 1.5e-44 Smith-Waterman score: 778; 99.1% identity (99.1% similar) in 117 aa overlap (1-116:1-117) 10 20 30 40 50 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQ-RKESKKPPAKLQPRALAGWLRPE :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: NP_001 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 70 80 90 100 110 >>NP_001128417 (OMIM: 601665,605353) appetite-regulating (104 aa) initn: 567 init1: 567 opt: 567 Z-score: 675.1 bits: 130.1 E(85289): 7.3e-31 Smith-Waterman score: 567; 97.7% identity (98.8% similar) in 86 aa overlap (31-116:19-104) 10 20 30 40 50 60 pF1KB6 MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQRKESKKPPAKLQPRALAGWLRPED : .::::::::::::::::::::::::::: NP_001 MFTCWWSYLRSTLAAVPGEASRVQRKESKKPPAKLQPRALAGWLRPED 10 20 30 40 70 80 90 100 110 pF1KB6 GGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK 50 60 70 80 90 100 116 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:54:32 2016 done: Fri Nov 4 23:54:33 2016 Total Scan time: 4.100 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]