FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6773, 118 aa 1>>>pF1KB6773 118 - 118 aa - 118 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5760+/-0.000232; mu= 7.8230+/- 0.015 mean_var=121.4169+/-24.844, 0's: 0 Z-trim(126.1): 16 B-trim: 4419 in 2/57 Lambda= 0.116395 statistics sampled from 51307 (51323) to 51307 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.871), E-opt: 0.2 (0.602), width: 16 Scan time: 5.360 The best scores are: opt bits E(85289) NP_055046 (OMIM: 108600,185880) vesicle-associated ( 118) 788 141.1 4.1e-34 NP_058439 (OMIM: 108600,185880) vesicle-associated ( 116) 754 135.4 2.1e-32 NP_001284367 (OMIM: 108600,185880) vesicle-associa ( 116) 754 135.4 2.1e-32 NP_954740 (OMIM: 108600,185880) vesicle-associated ( 117) 754 135.4 2.1e-32 NP_055047 (OMIM: 185881) vesicle-associated membra ( 116) 609 111.0 4.5e-25 NP_001317054 (OMIM: 185881) vesicle-associated mem ( 118) 608 110.8 5.1e-25 NP_004772 (OMIM: 603657) vesicle-associated membra ( 100) 463 86.4 9.6e-18 XP_016858330 (OMIM: 603657) PREDICTED: vesicle-ass ( 122) 458 85.7 2e-17 NP_001172056 (OMIM: 606909) vesicle-associated mem ( 140) 270 54.1 7.1e-08 NP_003753 (OMIM: 606909) vesicle-associated membra ( 141) 270 54.1 7.1e-08 NP_003752 (OMIM: 603177) vesicle-associated membra ( 100) 224 46.3 1.2e-05 NP_006625 (OMIM: 607029) vesicle-associated membra ( 116) 187 40.1 0.00096 >>NP_055046 (OMIM: 108600,185880) vesicle-associated mem (118 aa) initn: 788 init1: 788 opt: 788 Z-score: 733.5 bits: 141.1 E(85289): 4.1e-34 Smith-Waterman score: 788; 100.0% identity (100.0% similar) in 118 aa overlap (1-118:1-118) 10 20 30 40 50 60 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT 70 80 90 100 110 >>NP_058439 (OMIM: 108600,185880) vesicle-associated mem (116 aa) initn: 754 init1: 754 opt: 754 Z-score: 702.8 bits: 135.4 E(85289): 2.1e-32 Smith-Waterman score: 754; 100.0% identity (100.0% similar) in 113 aa overlap (1-113:1-113) 10 20 30 40 50 60 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVRRD 70 80 90 100 110 >>NP_001284367 (OMIM: 108600,185880) vesicle-associated (116 aa) initn: 754 init1: 754 opt: 754 Z-score: 702.8 bits: 135.4 E(85289): 2.1e-32 Smith-Waterman score: 754; 100.0% identity (100.0% similar) in 113 aa overlap (1-113:1-113) 10 20 30 40 50 60 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVRRG 70 80 90 100 110 >>NP_954740 (OMIM: 108600,185880) vesicle-associated mem (117 aa) initn: 754 init1: 754 opt: 754 Z-score: 702.7 bits: 135.4 E(85289): 2.1e-32 Smith-Waterman score: 754; 100.0% identity (100.0% similar) in 113 aa overlap (1-113:1-113) 10 20 30 40 50 60 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVSKYR 70 80 90 100 110 >>NP_055047 (OMIM: 185881) vesicle-associated membrane p (116 aa) initn: 628 init1: 597 opt: 609 Z-score: 571.2 bits: 111.0 E(85289): 4.5e-25 Smith-Waterman score: 609; 78.3% identity (89.2% similar) in 120 aa overlap (1-118:1-116) 10 20 30 40 50 pF1KB6 MSAPAQ--PPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLER ::: : ::: . : ::::.::::.:::::::::::::.:::::.:::::::::: NP_055 MSATAATAPPA----APAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLER 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 DQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT ::::::::::::::::::::::.::::::::::::: ::::.::.:::::...:..:: : NP_055 DQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST 60 70 80 90 100 110 >>NP_001317054 (OMIM: 185881) vesicle-associated membran (118 aa) initn: 628 init1: 597 opt: 608 Z-score: 570.2 bits: 110.8 E(85289): 5.1e-25 Smith-Waterman score: 608; 77.8% identity (90.6% similar) in 117 aa overlap (2-118:6-118) 10 20 30 40 50 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVL .: . ::: . : ::::.::::.:::::::::::::.:::::.:::::::: NP_001 MDRSATAATAPPA----APAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 ERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYF ::::::::::::::::::::::::.::::::::::::: ::::.::.:::::...:..:: NP_001 ERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYF 60 70 80 90 100 110 pF1KB6 FT : NP_001 ST >>NP_004772 (OMIM: 603657) vesicle-associated membrane p (100 aa) initn: 454 init1: 437 opt: 463 Z-score: 439.6 bits: 86.4 E(85289): 9.6e-18 Smith-Waterman score: 463; 73.1% identity (88.2% similar) in 93 aa overlap (23-115:4-96) 10 20 30 40 50 60 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ :: ::::::::: ::.:::::.:::::::::::: NP_004 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQ 10 20 30 40 70 80 90 100 110 pF1KB6 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT ::::::::::::::::::::.:::::::::::::::: . .. .:....:... NP_004 KLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLVIFIIIIIVWVVSS 50 60 70 80 90 100 >>XP_016858330 (OMIM: 603657) PREDICTED: vesicle-associa (122 aa) initn: 454 init1: 437 opt: 458 Z-score: 433.8 bits: 85.7 E(85289): 2e-17 Smith-Waterman score: 458; 76.1% identity (84.8% similar) in 92 aa overlap (23-114:4-94) 10 20 30 40 50 60 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ :: ::::::::: ::.:::::.:::::::::::: XP_016 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQ 10 20 30 40 70 80 90 100 110 pF1KB6 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT ::::::::::::::::::::.:::::::::::::::: . : .: ..:.: XP_016 KLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAI-GITVLVIFIIIIIGELPFS 50 60 70 80 90 100 XP_016 KLIGKVFSMCSQTIDFVYKNSD 110 120 >>NP_001172056 (OMIM: 606909) vesicle-associated membran (140 aa) initn: 258 init1: 237 opt: 270 Z-score: 262.4 bits: 54.1 E(85289): 7.1e-08 Smith-Waterman score: 270; 35.8% identity (78.9% similar) in 95 aa overlap (20-114:39-132) 10 20 30 40 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIR :: :: . : .....: ::.::.:... NP_001 LNDDDVTGSVKSERRNLLEDDSDEEEDFFLGPSGPRFG-PRNDKIKHVQNQVDEVIDVMQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 VNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIV :. ::.:: ..:.::.:....:. .:. : . . .:.:..::..::. ... . ::.. NP_001 ENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALVAAILL 70 80 90 100 110 120 110 pF1KB6 VVIVIYFFT .::.: NP_001 LVIIILIVMKYRT 130 140 >>NP_003753 (OMIM: 606909) vesicle-associated membrane p (141 aa) initn: 258 init1: 237 opt: 270 Z-score: 262.4 bits: 54.1 E(85289): 7.1e-08 Smith-Waterman score: 270; 35.8% identity (78.9% similar) in 95 aa overlap (20-114:40-133) 10 20 30 40 pF1KB6 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIR :: :: . : .....: ::.::.:... NP_003 NDDDVTGSVKSERRNLLEDDSDEEEDFFLRGPSGPRFG-PRNDKIKHVQNQVDEVIDVMQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 VNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIV :. ::.:: ..:.::.:....:. .:. : . . .:.:..::..::. ... . ::.. NP_003 ENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALVAAILL 70 80 90 100 110 120 110 pF1KB6 VVIVIYFFT .::.: NP_003 LVIIILIVMKYRT 130 140 118 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:08:53 2016 done: Sat Nov 5 20:08:54 2016 Total Scan time: 5.360 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]