Result of FASTA (omim) for
pF1KB6777
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6777, 119 aa
1>>>pF1KB6777 119 - 119 aa - 119 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7778+/-0.000331; mu= 12.7192+/- 0.020
mean_var=56.4535+/-11.876, 0's: 0 Z-trim(114.3): 99 B-trim: 1023 in 1/54
Lambda= 0.170698
statistics sampled from 23971 (24079) to 23971 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.282), width: 16
Scan time: 4.210
The best scores are: opt bits E(85289)
NP_004039 (OMIM: 105200,109700,241600) beta-2-micr ( 119) 791 202.5 1.3e-52
XP_005254606 (OMIM: 105200,109700,241600) PREDICTE ( 122) 763 195.6 1.6e-50
NP_291032 (OMIM: 142880) HLA class II histocompati ( 260) 229 64.3 1.2e-10
NP_001229453 (OMIM: 142880) HLA class II histocomp ( 260) 229 64.3 1.2e-10
NP_001229454 (OMIM: 142880) HLA class II histocomp ( 260) 229 64.3 1.2e-10
NP_002112 (OMIM: 142858) HLA class II histocompati ( 258) 215 60.8 1.3e-09
NP_001230894 (OMIM: 126200,142857,180300,181000) m ( 266) 212 60.1 2.2e-09
NP_002115 (OMIM: 126200,142857,180300,181000) majo ( 266) 199 56.9 2e-08
XP_011546040 (OMIM: 126200,142857,180300,181000) P ( 266) 199 56.9 2e-08
NP_002116 (OMIM: 604776) major histocompatibility ( 266) 196 56.2 3.3e-08
XP_011512864 (OMIM: 604776) PREDICTED: major histo ( 276) 196 56.2 3.4e-08
NP_002109 (OMIM: 142856) HLA class II histocompati ( 263) 195 55.9 3.9e-08
XP_011512863 (OMIM: 615161) PREDICTED: HLA class I ( 219) 193 55.4 4.7e-08
NP_001185787 (OMIM: 615161) HLA class II histocomp ( 227) 193 55.4 4.9e-08
XP_011512862 (OMIM: 615161) PREDICTED: HLA class I ( 256) 193 55.4 5.4e-08
NP_001287719 (OMIM: 615161) HLA class II histocomp ( 264) 193 55.4 5.5e-08
NP_072049 (OMIM: 612735) major histocompatibility ( 266) 193 55.4 5.5e-08
XP_005249108 (OMIM: 615161) PREDICTED: HLA class I ( 275) 193 55.4 5.7e-08
NP_001230891 (OMIM: 123400,126200,212750,604305) H ( 261) 190 54.7 9.1e-08
NP_002114 (OMIM: 123400,126200,212750,604305) HLA ( 261) 189 54.4 1.1e-07
NP_001230890 (OMIM: 123400,126200,212750,604305) H ( 269) 189 54.5 1.1e-07
NP_061984 (OMIM: 142860) HLA class II histocompati ( 254) 188 54.2 1.3e-07
NP_002111 (OMIM: 600629) HLA class II histocompati ( 273) 186 53.7 1.9e-07
XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 177 51.5 7.5e-07
XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 177 51.5 1e-06
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 177 51.6 1e-06
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 177 51.6 1.1e-06
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 177 51.6 1.2e-06
XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 177 51.6 1.2e-06
XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 177 51.6 1.3e-06
XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 177 51.6 1.3e-06
NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 177 51.6 1.3e-06
NP_001307581 (OMIM: 188370) T-cell surface glycopr ( 316) 162 47.8 1.3e-05
NP_001754 (OMIM: 188370) T-cell surface glycoprote ( 327) 162 47.9 1.3e-05
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 153 45.7 6.6e-05
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 153 45.7 6.6e-05
NP_006111 (OMIM: 142855) HLA class II histocompati ( 261) 151 45.1 7.1e-05
NP_001756 (OMIM: 188340) T-cell surface glycoprote ( 333) 152 45.4 7.3e-05
NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 152 45.4 7.4e-05
XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 152 45.4 7.5e-05
XP_005245636 (OMIM: 188340) PREDICTED: T-cell surf ( 346) 152 45.4 7.5e-05
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 149 44.6 9.8e-05
NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 149 44.6 0.00011
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 149 44.7 0.00012
XP_011508429 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 140 42.3 0.00042
XP_005245640 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 140 42.3 0.00042
XP_006711684 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 140 42.3 0.00042
NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 142 43.0 0.00043
NP_001755 (OMIM: 188360) T-cell surface glycoprote ( 333) 141 42.7 0.00048
NP_001229971 (OMIM: 142840,177900,609423) HLA clas ( 366) 141 42.7 0.00051
>>NP_004039 (OMIM: 105200,109700,241600) beta-2-microglo (119 aa)
initn: 791 init1: 791 opt: 791 Z-score: 1065.3 bits: 202.5 E(85289): 1.3e-52
Smith-Waterman score: 791; 100.0% identity (100.0% similar) in 119 aa overlap (1-119:1-119)
10 20 30 40 50 60
pF1KB6 MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLL
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 KNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM
70 80 90 100 110
>>XP_005254606 (OMIM: 105200,109700,241600) PREDICTED: b (122 aa)
initn: 763 init1: 763 opt: 763 Z-score: 1027.9 bits: 195.6 E(85289): 1.6e-50
Smith-Waterman score: 763; 98.3% identity (99.1% similar) in 117 aa overlap (1-117:1-117)
10 20 30 40 50 60
pF1KB6 MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLL
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 KNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::: .
XP_005 KNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWGKSYI
70 80 90 100 110 120
XP_005 LL
>>NP_291032 (OMIM: 142880) HLA class II histocompatibili (260 aa)
initn: 163 init1: 117 opt: 229 Z-score: 312.4 bits: 64.3 E(85289): 1.2e-10
Smith-Waterman score: 229; 35.4% identity (64.6% similar) in 99 aa overlap (19-116:112-210)
10 20 30 40
pF1KB6 MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVS
.: . :.. :. ..:.: :. : : :...
NP_291 AFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVELGQPNTLICHID
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB6 GFHPSDIEVDLLKNGERI-EKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTL
: : ..: : ::: . : : .: . :.::. ..: :.:. .: : :::.: :
NP_291 KFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDFYDCRVEHWGL
150 160 170 180 190 200
110
pF1KB6 SQPKIVKWDRDM
.:: . .:.
NP_291 DQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGTL
210 220 230 240 250 260
>>NP_001229453 (OMIM: 142880) HLA class II histocompatib (260 aa)
initn: 163 init1: 117 opt: 229 Z-score: 312.4 bits: 64.3 E(85289): 1.2e-10
Smith-Waterman score: 229; 35.4% identity (64.6% similar) in 99 aa overlap (19-116:112-210)
10 20 30 40
pF1KB6 MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVS
.: . :.. :. ..:.: :. : : :...
NP_001 AFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVELGQPNTLICHID
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB6 GFHPSDIEVDLLKNGERI-EKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTL
: : ..: : ::: . : : .: . :.::. ..: :.:. .: : :::.: :
NP_001 KFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDFYDCRVEHWGL
150 160 170 180 190 200
110
pF1KB6 SQPKIVKWDRDM
.:: . .:.
NP_001 DQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGTL
210 220 230 240 250 260
>>NP_001229454 (OMIM: 142880) HLA class II histocompatib (260 aa)
initn: 163 init1: 117 opt: 229 Z-score: 312.4 bits: 64.3 E(85289): 1.2e-10
Smith-Waterman score: 229; 35.4% identity (64.6% similar) in 99 aa overlap (19-116:112-210)
10 20 30 40
pF1KB6 MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVS
.: . :.. :. ..:.: :. : : :...
NP_001 AFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVELGQPNTLICHID
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB6 GFHPSDIEVDLLKNGERI-EKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTL
: : ..: : ::: . : : .: . :.::. ..: :.:. .: : :::.: :
NP_001 KFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDFYDCRVEHWGL
150 160 170 180 190 200
110
pF1KB6 SQPKIVKWDRDM
.:: . .:.
NP_001 DQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGTL
210 220 230 240 250 260
>>NP_002112 (OMIM: 142858) HLA class II histocompatibili (258 aa)
initn: 188 init1: 133 opt: 215 Z-score: 293.8 bits: 60.8 E(85289): 1.3e-09
Smith-Waterman score: 215; 33.7% identity (66.3% similar) in 104 aa overlap (15-115:112-215)
10 20 30 40
pF1KB6 MSRSVALAVLALLSLSGLEAIQRT--PKIQVYSRHPAENGKSNF
:.: ..:: :...: . . . :.
NP_002 RPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNL
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB6 LNCYVSGFHPSDIEVDLLKNG-ERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACR
: :.:. :.:..:.: . :: :. : ..: . ::.: .: . :.:: . : :.:.
NP_002 LVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQ
150 160 170 180 190 200
110
pF1KB6 VNHVTLSQPKIVKWDRDM
:.:..:..: :.:
NP_002 VEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRGSA
210 220 230 240 250
>>NP_001230894 (OMIM: 126200,142857,180300,181000) major (266 aa)
initn: 146 init1: 112 opt: 212 Z-score: 289.6 bits: 60.1 E(85289): 2.2e-09
Smith-Waterman score: 212; 36.4% identity (62.6% similar) in 99 aa overlap (21-115:120-217)
10 20 30 40
pF1KB6 MSRSVALAVLALLSLSGLEAIQRT--PKIQVYSRHPAENGKSNFLNCYVS
.:: ::. :: . . :.: : ::
NP_001 WNSQKDLLEQKRGRVDNYCRHNYGVVESFTVQRRVHPKVTVYPSKTQPLQHHNLLVCSVS
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB6 GFHPSDIEVDLLKNGERIEK--VEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVT
::.:..::: ..::.. :: : . : . ::.: : . : .: . :.:.:.: .
NP_001 GFYPGSIEVRWFRNGQE-EKTGVVSTGLIHNGDWTFQTLVMLETVPRSGEVYTCQVEHPS
150 160 170 180 190 200
110
pF1KB6 LSQPKIVKWDRDM
...: :.:
NP_001 VTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPRGFLS
210 220 230 240 250 260
>>NP_002115 (OMIM: 126200,142857,180300,181000) major hi (266 aa)
initn: 140 init1: 106 opt: 199 Z-score: 272.3 bits: 56.9 E(85289): 2e-08
Smith-Waterman score: 199; 35.4% identity (61.6% similar) in 99 aa overlap (21-115:120-217)
10 20 30 40
pF1KB6 MSRSVALAVLALLSLSGLEAIQRT--PKIQVYSRHPAENGKSNFLNCYVS
.:: ::. :: . . :.: : ::
NP_002 WNSQKDILEQARAAVDTYCRHNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVS
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB6 GFHPSDIEVDLLKNGERIEK--VEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVT
::.:..::: . ::.. :: . . : . ::.: : . : .: . :.:.:.: .
NP_002 GFYPGSIEVRWFLNGQE-EKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS
150 160 170 180 190 200
110
pF1KB6 LSQPKIVKWDRDM
...: :.:
NP_002 VTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
210 220 230 240 250 260
>>XP_011546040 (OMIM: 126200,142857,180300,181000) PREDI (266 aa)
initn: 126 init1: 92 opt: 199 Z-score: 272.3 bits: 56.9 E(85289): 2e-08
Smith-Waterman score: 199; 35.4% identity (61.6% similar) in 99 aa overlap (21-115:120-217)
10 20 30 40
pF1KB6 MSRSVALAVLALLSLSGLEAIQRT--PKIQVYSRHPAENGKSNFLNCYVS
.:: :.. :: . . :.: : ::
XP_011 WNSQKDILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVS
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB6 GFHPSDIEVDLLKNGERIEK--VEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVT
::.:..::: ..::.. :: : . : . ::.: : . : .: . :.:.:.: .
XP_011 GFYPGSIEVRWFRNGQE-EKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS
150 160 170 180 190 200
110
pF1KB6 LSQPKIVKWDRDM
. .: :.:
XP_011 VMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
210 220 230 240 250 260
>>NP_002116 (OMIM: 604776) major histocompatibility comp (266 aa)
initn: 133 init1: 99 opt: 196 Z-score: 268.3 bits: 56.2 E(85289): 3.3e-08
Smith-Waterman score: 196; 34.3% identity (62.6% similar) in 99 aa overlap (21-115:120-217)
10 20 30 40
pF1KB6 MSRSVALAVLALLSLSGLEAIQRT--PKIQVYSRHPAENGKSNFLNCYVS
.:: ::. :: . . :.: : :.
NP_002 WNSQKDFLEDRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYPARTQTLQHHNLLVCSVN
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB6 GFHPSDIEVDLLKNGERIEK--VEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVT
::.:..::: ..:... :: : . : . ::.: : . : .: . :.:.:.: .
NP_002 GFYPGSIEVRWFRNSQE-EKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS
150 160 170 180 190 200
110
pF1KB6 LSQPKIVKWDRDM
...: :.:
NP_002 VTSPLTVEWRAQSESAQSKMLSGVGGFVLGLLFLGAGLFIYFKNQKGHSGLHPTGLVS
210 220 230 240 250 260
119 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:58:12 2016 done: Fri Nov 4 23:58:12 2016
Total Scan time: 4.210 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]