FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6781, 120 aa 1>>>pF1KB6781 120 - 120 aa - 120 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7540+/-0.000297; mu= 12.8954+/- 0.018 mean_var=51.5989+/-10.191, 0's: 0 Z-trim(116.4): 65 B-trim: 0 in 0/50 Lambda= 0.178548 statistics sampled from 27512 (27584) to 27512 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.323), width: 16 Scan time: 4.440 The best scores are: opt bits E(85289) XP_005258077 (OMIM: 601394) PREDICTED: C-C motif c ( 120) 795 211.9 2e-55 NP_004581 (OMIM: 601394) C-C motif chemokine 16 pr ( 120) 795 211.9 2e-55 NP_996890 (OMIM: 603782) C-C motif chemokine 4-lik ( 92) 249 71.2 3.5e-13 NP_002975 (OMIM: 182284) C-C motif chemokine 4 pre ( 92) 247 70.7 5.1e-13 NP_116739 (OMIM: 601392) C-C motif chemokine 14 is ( 93) 246 70.4 6.1e-13 NP_066286 (OMIM: 601395,609423) C-C motif chemokin ( 93) 240 68.9 1.8e-12 NP_001001437 (OMIM: 609468) C-C motif chemokine 3- ( 93) 240 68.9 1.8e-12 NP_002974 (OMIM: 182283,609423) C-C motif chemokin ( 92) 232 66.8 7.4e-12 NP_002976 (OMIM: 187011) C-C motif chemokine 5 iso ( 91) 219 63.4 7.4e-11 NP_006264 (OMIM: 158106) C-C motif chemokine 7 pre ( 99) 218 63.2 9.5e-11 NP_116738 (OMIM: 601392) C-C motif chemokine 14 is ( 109) 215 62.5 1.8e-10 NP_001278397 (OMIM: 610757) C-C motif chemokine 4- ( 87) 206 60.1 7.3e-10 NP_005614 (OMIM: 602283) C-C motif chemokine 8 pre ( 99) 195 57.3 5.8e-09 NP_002979 (OMIM: 603757) C-C motif chemokine 18 pr ( 89) 192 56.5 9e-09 NP_005399 (OMIM: 601391) C-C motif chemokine 13 pr ( 98) 190 56.0 1.4e-08 NP_002978 (OMIM: 601520) C-C motif chemokine 17 pr ( 94) 187 55.2 2.3e-08 XP_011521558 (OMIM: 601520) PREDICTED: C-C motif c ( 122) 187 55.3 2.9e-08 XP_016879019 (OMIM: 601520) PREDICTED: C-C motif c ( 123) 187 55.3 2.9e-08 NP_002980 (OMIM: 602737) C-C motif chemokine 21 pr ( 134) 185 54.8 4.5e-08 XP_011516306 (OMIM: 602737) PREDICTED: C-C motif c ( 145) 185 54.8 4.8e-08 XP_016867161 (OMIM: 604697) PREDICTED: C-C motif c ( 94) 180 53.4 8.1e-08 NP_006063 (OMIM: 604697) C-C motif chemokine 26 pr ( 94) 180 53.4 8.1e-08 XP_016867160 (OMIM: 604697) PREDICTED: C-C motif c ( 148) 180 53.5 1.2e-07 NP_002973 (OMIM: 158105,182940,607948,609423) C-C ( 99) 174 51.9 2.5e-07 NP_002977 (OMIM: 600807,601156,609423) eotaxin pre ( 97) 172 51.3 3.5e-07 NP_002982 (OMIM: 602495) C-C motif chemokine 24 pr ( 119) 162 48.8 2.5e-06 XP_011514761 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 162 48.8 2.5e-06 XP_011514762 (OMIM: 602495) PREDICTED: C-C motif c ( 119) 162 48.8 2.5e-06 NP_001123518 (OMIM: 601960) C-C motif chemokine 20 ( 95) 160 48.3 2.9e-06 NP_004582 (OMIM: 601960) C-C motif chemokine 20 is ( 96) 160 48.3 2.9e-06 NP_006265 (OMIM: 602227) C-C motif chemokine 19 pr ( 98) 155 47.0 7.3e-06 NP_002981 (OMIM: 602957) C-C motif chemokine 22 pr ( 93) 151 45.9 1.4e-05 XP_016879020 (OMIM: 602957) PREDICTED: C-C motif c ( 93) 151 45.9 1.4e-05 NP_001278401 (OMIM: 610757) C-C motif chemokine 4- ( 96) 149 45.4 2.1e-05 NP_665905 (OMIM: 602494) C-C motif chemokine 23 is ( 120) 145 44.4 5.1e-05 NP_005055 (OMIM: 602494) C-C motif chemokine 23 is ( 137) 145 44.5 5.8e-05 NP_116741 (OMIM: 601393) C-C motif chemokine 15 pr ( 113) 142 43.7 8.3e-05 NP_001278400 (OMIM: 610757) C-C motif chemokine 4- ( 103) 140 43.1 0.00011 NP_001278399 (OMIM: 610757) C-C motif chemokine 4- ( 64) 136 42.0 0.00015 NP_001278398 (OMIM: 610757) C-C motif chemokine 4- ( 64) 136 42.0 0.00015 NP_001278402 (OMIM: 610757) C-C motif chemokine 4- ( 86) 136 42.1 0.00019 NP_001278404 (OMIM: 610757) C-C motif chemokine 4- ( 103) 136 42.1 0.00023 NP_954637 (OMIM: 600835,609423) stromal cell-deriv ( 89) 130 40.5 0.00058 NP_000600 (OMIM: 600835,609423) stromal cell-deriv ( 93) 130 40.5 0.0006 NP_002972 (OMIM: 182281) C-C motif chemokine 1 pre ( 96) 129 40.3 0.00074 NP_001029058 (OMIM: 600835,609423) stromal cell-de ( 119) 130 40.6 0.00074 NP_001171605 (OMIM: 600835,609423) stromal cell-de ( 140) 130 40.6 0.00085 XP_016882611 (OMIM: 602565) PREDICTED: C-C motif c ( 149) 119 37.8 0.0064 NP_001188288 (OMIM: 602565) C-C motif chemokine 25 ( 149) 119 37.8 0.0064 XP_011526479 (OMIM: 602565) PREDICTED: C-C motif c ( 150) 119 37.8 0.0064 >>XP_005258077 (OMIM: 601394) PREDICTED: C-C motif chemo (120 aa) initn: 795 init1: 795 opt: 795 Z-score: 1115.9 bits: 211.9 E(85289): 2e-55 Smith-Waterman score: 795; 100.0% identity (100.0% similar) in 120 aa overlap (1-120:1-120) 10 20 30 40 50 60 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ 70 80 90 100 110 120 >>NP_004581 (OMIM: 601394) C-C motif chemokine 16 precur (120 aa) initn: 795 init1: 795 opt: 795 Z-score: 1115.9 bits: 211.9 E(85289): 2e-55 Smith-Waterman score: 795; 100.0% identity (100.0% similar) in 120 aa overlap (1-120:1-120) 10 20 30 40 50 60 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ 70 80 90 100 110 120 >>NP_996890 (OMIM: 603782) C-C motif chemokine 4-like pr (92 aa) initn: 234 init1: 136 opt: 249 Z-score: 357.6 bits: 71.2 E(85289): 3.5e-13 Smith-Waterman score: 249; 40.4% identity (71.3% similar) in 94 aa overlap (1-93:1-91) 10 20 30 40 50 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALN- ::. ..::::::. . : . : .: . :..::..: . ::: .:: : .. . NP_996 MKLCVTVLSLLVLVAAFCSLALS---APMGSDPPTACCFSYTARKLPRNFVVDYYETSSL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNS : ::..: :::...::..:...:::::. : .: NP_996 CSQPAVVFQTKRGKQVCADPSESWVQEYVYDLELN 60 70 80 90 120 pF1KB6 Q >>NP_002975 (OMIM: 182284) C-C motif chemokine 4 precurs (92 aa) initn: 232 init1: 137 opt: 247 Z-score: 354.8 bits: 70.7 E(85289): 5.1e-13 Smith-Waterman score: 247; 39.4% identity (71.3% similar) in 94 aa overlap (1-93:1-91) 10 20 30 40 50 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALN- ::. ..::::.:. . : . : .: . :..::..: . ::: .:: : .. . NP_002 MKLCVTVLSLLMLVAAFCSPALS---APMGSDPPTACCFSYTARKLPRNFVVDYYETSSL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNS : ::..: :::...::..:...:::::. : .: NP_002 CSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN 60 70 80 90 120 pF1KB6 Q >>NP_116739 (OMIM: 601392) C-C motif chemokine 14 isofor (93 aa) initn: 249 init1: 161 opt: 246 Z-score: 353.3 bits: 70.4 E(85289): 6.1e-13 Smith-Waterman score: 246; 41.3% identity (69.6% similar) in 92 aa overlap (1-90:1-89) 10 20 30 40 50 pF1KB6 MKVSEAALSLLVLILI-ITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALN ::.: ::. ...:: : . . ..:. . : :: ::. : .::. .. : .. . NP_116 MKISVAAIPFFLLITIALGTKTESSSRGPY---HPSECCFTYTTYKIPRQRIMDYYETNS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 -CHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLN : :.:.:.:::.. :::::.: :::.:::: NP_116 QCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN 60 70 80 90 120 pF1KB6 SQ >>NP_066286 (OMIM: 601395,609423) C-C motif chemokine 3- (93 aa) initn: 203 init1: 125 opt: 240 Z-score: 345.0 bits: 68.9 E(85289): 1.8e-12 Smith-Waterman score: 240; 35.1% identity (74.5% similar) in 94 aa overlap (1-93:1-91) 10 20 30 40 50 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGY-RKALN :.:: :::..:. . . . : : . ..::..::..: . .:. ... : . . . NP_066 MQVSTAALAVLLCTMALCNQVLSAPLA---ADTPTACCFSYTSRQIPQNFIADYFETSSQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNS : :..::.:::.:.::..:...:::.:..: .: NP_066 CSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 120 pF1KB6 Q >>NP_001001437 (OMIM: 609468) C-C motif chemokine 3-like (93 aa) initn: 203 init1: 125 opt: 240 Z-score: 345.0 bits: 68.9 E(85289): 1.8e-12 Smith-Waterman score: 240; 35.1% identity (74.5% similar) in 94 aa overlap (1-93:1-91) 10 20 30 40 50 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGY-RKALN :.:: :::..:. . . . : : . ..::..::..: . .:. ... : . . . NP_001 MQVSTAALAVLLCTMALCNQVLSAPLA---ADTPTACCFSYTSRQIPQNFIADYFETSSQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNS : :..::.:::.:.::..:...:::.:..: .: NP_001 CSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 120 pF1KB6 Q >>NP_002974 (OMIM: 182283,609423) C-C motif chemokine 3 (92 aa) initn: 204 init1: 126 opt: 232 Z-score: 333.9 bits: 66.8 E(85289): 7.4e-12 Smith-Waterman score: 232; 36.2% identity (74.5% similar) in 94 aa overlap (1-93:1-90) 10 20 30 40 50 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGY-RKALN :.:: :::. .:. : : .: .. ..::..::..: . .:. ... : . . . NP_002 MQVSTAALA----VLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNS : :..::.:::.:.::..:...:::.:..: .: NP_002 CSKPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA 60 70 80 90 120 pF1KB6 Q >>NP_002976 (OMIM: 187011) C-C motif chemokine 5 isoform (91 aa) initn: 216 init1: 136 opt: 219 Z-score: 315.9 bits: 63.4 E(85289): 7.4e-11 Smith-Waterman score: 219; 38.2% identity (66.3% similar) in 89 aa overlap (1-88:1-85) 10 20 30 40 50 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGY-RKALN :::: :::..... . . . ..: . .:: ::. : . ::: . : . . NP_002 MKVSAAALAVILIATALCAPASASPYSSD--TTP--CCFAYIARPLPRAHIKEYFYTSGK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNS : ::..:::..::.::.::. ::.::: NP_002 CSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS 60 70 80 90 >>NP_006264 (OMIM: 158106) C-C motif chemokine 7 precurs (99 aa) initn: 230 init1: 115 opt: 218 Z-score: 313.9 bits: 63.2 E(85289): 9.5e-11 Smith-Waterman score: 218; 35.2% identity (68.1% similar) in 91 aa overlap (1-89:1-88) 10 20 30 40 50 60 pF1KB6 MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNC ::.: : : ::. .. . .: : .:: .::: .. .: .:.. . .::.. . NP_006 MKASAALLCLLLTAAAFSPQGLAQ---PVGINTSTTCCYRFINKKIPKQRLESYRRTTSS 10 20 30 40 50 70 80 90 100 110 pF1KB6 HLP--AIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLN : : :.:: :: ..:.:..:.. :::...: NP_006 HCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL 60 70 80 90 120 pF1KB6 SQ 120 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:31:38 2016 done: Sat Nov 5 17:31:38 2016 Total Scan time: 4.440 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]