FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6790, 155 aa 1>>>pF1KB6790 155 - 155 aa - 155 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1925+/-0.000667; mu= 11.8853+/- 0.040 mean_var=60.6756+/-12.271, 0's: 0 Z-trim(109.5): 36 B-trim: 0 in 0/51 Lambda= 0.164652 statistics sampled from 10895 (10931) to 10895 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.336), width: 16 Scan time: 1.830 The best scores are: opt bits E(32554) CCDS4275.1 FGF1 gene_id:2246|Hs108|chr5 ( 155) 1047 256.6 4.4e-69 CCDS34059.1 FGF2 gene_id:2247|Hs108|chr4 ( 288) 531 134.2 5.9e-32 CCDS4276.1 FGF1 gene_id:2246|Hs108|chr5 ( 60) 386 99.4 3.6e-22 CCDS9298.1 FGF9 gene_id:2254|Hs108|chr13 ( 208) 329 86.1 1.2e-17 CCDS5998.1 FGF20 gene_id:26281|Hs108|chr8 ( 211) 328 85.9 1.5e-17 CCDS75996.1 FGF16 gene_id:8823|Hs108|chrX ( 207) 327 85.7 1.7e-17 CCDS9501.1 FGF14 gene_id:2259|Hs108|chr13 ( 247) 280 74.5 4.6e-14 CCDS9500.1 FGF14 gene_id:2259|Hs108|chr13 ( 252) 280 74.5 4.7e-14 CCDS10131.1 FGF7 gene_id:2252|Hs108|chr15 ( 194) 275 73.3 8.5e-14 CCDS3950.1 FGF10 gene_id:2255|Hs108|chr5 ( 208) 270 72.1 2.1e-13 CCDS12037.1 FGF22 gene_id:27006|Hs108|chr19 ( 170) 265 70.9 3.9e-13 CCDS34021.1 FGF5 gene_id:2250|Hs108|chr4 ( 268) 267 71.5 4.2e-13 CCDS14664.1 FGF13 gene_id:2258|Hs108|chrX ( 192) 265 70.9 4.4e-13 CCDS46983.1 FGF12 gene_id:2257|Hs108|chr3 ( 181) 263 70.4 5.8e-13 CCDS55512.1 FGF13 gene_id:2258|Hs108|chrX ( 199) 262 70.2 7.4e-13 CCDS3301.1 FGF12 gene_id:2257|Hs108|chr3 ( 243) 263 70.5 7.4e-13 CCDS55511.1 FGF13 gene_id:2258|Hs108|chrX ( 226) 260 69.8 1.1e-12 CCDS14665.1 FGF13 gene_id:2258|Hs108|chrX ( 245) 260 69.8 1.2e-12 CCDS55513.1 FGF13 gene_id:2258|Hs108|chrX ( 255) 260 69.8 1.3e-12 CCDS11105.1 FGF11 gene_id:2256|Hs108|chr17 ( 225) 251 67.6 5e-12 CCDS8194.1 FGF4 gene_id:2249|Hs108|chr11 ( 206) 245 66.2 1.2e-11 CCDS8527.1 FGF6 gene_id:2251|Hs108|chr12 ( 208) 235 63.8 6.5e-11 >>CCDS4275.1 FGF1 gene_id:2246|Hs108|chr5 (155 aa) initn: 1047 init1: 1047 opt: 1047 Z-score: 1353.8 bits: 256.6 E(32554): 4.4e-69 Smith-Waterman score: 1047; 100.0% identity (100.0% similar) in 155 aa overlap (1-155:1-155) 10 20 30 40 50 60 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEK 70 80 90 100 110 120 130 140 150 pF1KB6 NWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD ::::::::::::::::::::::::::::::::::: CCDS42 NWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD 130 140 150 >>CCDS34059.1 FGF2 gene_id:2247|Hs108|chr4 (288 aa) initn: 512 init1: 394 opt: 531 Z-score: 687.2 bits: 134.2 E(32554): 5.9e-32 Smith-Waterman score: 531; 54.1% identity (77.1% similar) in 157 aa overlap (1-154:134-288) 10 20 pF1KB6 MAEGEITTFTALTEKFN---LPPGNYKKPK :: : :::. :: : . .:::..: :: CCDS34 RVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPK 110 120 130 140 150 160 30 40 50 60 70 80 pF1KB6 LLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGL :::.::: :::: ::: :::.:..:: ::.:::.:: : : ::.. ...:::: :: CCDS34 RLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGR 170 180 190 200 210 220 90 100 110 120 130 140 pF1KB6 LYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF : .:. ..::.:.:::: :.:::: :.:.. .:.:.::..:. : : .: ::::::: CCDS34 LLASKCVTDECFFFERLESNNYNTYRSRKYT--SWYVALKRTGQYKLGSKTGPGQKAILF 230 240 250 260 270 280 150 pF1KB6 LPLPVSSD ::. ..: CCDS34 LPMSAKS >>CCDS4276.1 FGF1 gene_id:2246|Hs108|chr5 (60 aa) initn: 386 init1: 386 opt: 386 Z-score: 511.5 bits: 99.4 E(32554): 3.6e-22 Smith-Waterman score: 386; 100.0% identity (100.0% similar) in 56 aa overlap (1-56:1-56) 10 20 30 40 50 60 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHTDTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEK >>CCDS9298.1 FGF9 gene_id:2254|Hs108|chr13 (208 aa) initn: 261 init1: 218 opt: 329 Z-score: 430.0 bits: 86.1 E(32554): 1.2e-17 Smith-Waterman score: 329; 42.1% identity (72.2% similar) in 133 aa overlap (27-155:64-195) 10 20 30 40 50 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQH . ::: .: : :.:.:.::..::: .. CCDS92 SDHLGQSEAGGLPRGPAVTDLDHLKGILRRRQLYCRTGFH-LEIFPNGTIQGTRKDHSRF 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB6 IQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISK- :.. . .:: : :.....: ::.:. : ::::. ..::.: :..::: :::: :. CCDS92 GILEFISIAVGLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNL 100 110 120 130 140 150 120 130 140 150 pF1KB6 -KHAE--KNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD ::.. . ..:.:.:.:. ..: ::. :: ::: ::. : CCDS92 YKHVDTGRRYYVALNKDGTPREGTRTKRHQKFTHFLPRPVDPDKVPELYKDILSQS 160 170 180 190 200 >>CCDS5998.1 FGF20 gene_id:26281|Hs108|chr8 (211 aa) initn: 321 init1: 224 opt: 328 Z-score: 428.7 bits: 85.9 E(32554): 1.5e-17 Smith-Waterman score: 328; 42.9% identity (70.7% similar) in 133 aa overlap (27-155:67-198) 10 20 30 40 50 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQH . ::: .: : :.:::::.:.:::. . CCDS59 LGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGFH-LQILPDGSVQGTRQDHSLF 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB6 IQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISK- :.. . .:: : :.....: ::.:. : ::::. . ::.: :..::: :::: :. CCDS59 GILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNI 100 110 120 130 140 150 120 130 140 150 pF1KB6 -KHAE--KNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD ::.. . .::.:.:.:. . : :.. :: ::: ::. . CCDS59 YKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPERVPELYKDLLMYT 160 170 180 190 200 210 >>CCDS75996.1 FGF16 gene_id:8823|Hs108|chrX (207 aa) initn: 217 init1: 217 opt: 327 Z-score: 427.5 bits: 85.7 E(32554): 1.7e-17 Smith-Waterman score: 327; 43.8% identity (71.5% similar) in 130 aa overlap (27-152:63-191) 10 20 30 40 50 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQH . ::: .: : :.:.:.::: ::: .. CCDS75 FLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFH-LEIFPNGTVHGTRHDHSRF 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB6 IQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISK- :.. . .:: . :.....: ::.:. : ::::. ..::.: :..::: :::: : CCDS75 GILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEENWYNTYASTL 100 110 120 130 140 150 120 130 140 150 pF1KB6 -KHA--EKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD ::. :....:.:.:.:: ..: ::. :: ::: :: CCDS75 YKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKLPSMSRDLFHYR 160 170 180 190 200 >>CCDS9501.1 FGF14 gene_id:2259|Hs108|chr13 (247 aa) initn: 298 init1: 169 opt: 280 Z-score: 366.0 bits: 74.5 E(32554): 4.6e-14 Smith-Waterman score: 280; 36.7% identity (66.4% similar) in 128 aa overlap (29-152:75-201) 10 20 30 40 50 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQ ::: .: ..:.. :::..:::.: : . CCDS95 VDIFSKVRIFGLKKRRLRRQDPQLKGIVTRLYCRQG-YYLQMHPDGALDGTKDDSTNSTL 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB6 LQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYIS---- ..: .. : :....:: :.::. .: :: :. . :: : : . ::.: : : CCDS95 FNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYR 110 120 130 140 150 160 120 130 140 150 pF1KB6 KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD .... . ::.::.:.:. .: :.. . : ::: :. CCDS95 QQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGV 170 180 190 200 210 220 CCDS95 TPSKSTSASAIMNGGKPVNKSKTT 230 240 >>CCDS9500.1 FGF14 gene_id:2259|Hs108|chr13 (252 aa) initn: 298 init1: 169 opt: 280 Z-score: 365.9 bits: 74.5 E(32554): 4.7e-14 Smith-Waterman score: 280; 36.7% identity (66.4% similar) in 128 aa overlap (29-152:80-206) 10 20 30 40 50 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQ ::: .: ..:.. :::..:::.: : . CCDS95 GTHMLQCLCGKSLKKNKNPTDPQLKGIVTRLYCRQG-YYLQMHPDGALDGTKDDSTNSTL 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB6 LQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYIS---- ..: .. : :....:: :.::. .: :: :. . :: : : . ::.: : : CCDS95 FNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYR 110 120 130 140 150 160 120 130 140 150 pF1KB6 KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD .... . ::.::.:.:. .: :.. . : ::: :. CCDS95 QQESGRAWFLGLNKEGQAMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGV 170 180 190 200 210 220 CCDS95 TPSKSTSASAIMNGGKPVNKSKTT 230 240 250 >>CCDS10131.1 FGF7 gene_id:2252|Hs108|chr15 (194 aa) initn: 260 init1: 199 opt: 275 Z-score: 361.2 bits: 73.3 E(32554): 8.5e-14 Smith-Waterman score: 275; 35.7% identity (65.0% similar) in 143 aa overlap (13-153:53-194) 10 20 30 40 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILP :.... :. . . :.: . .::: CCDS10 CLVGTISLACNDMTPEQMATNVNCSSPERHTRSYDYMEGGDIRVRRLFCRTQW-YLRIDK 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB6 DGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLE : : ::.. .... ... . .:: : ::..:. ::::. .: ::... ::.: : : CCDS10 RGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLAMNKEGKLYAKKECNEDCNFKE 90 100 110 120 130 140 110 120 130 140 150 pF1KB6 RLEENHYNTYISKK--HAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD . ::::::: : : : . ::.:...: :: .:. ::. :::. .. CCDS10 LILENHYNTYASAKWTHNGGEMFVALNQKGIPVRGKKTKKEQKTAHFLPMAIT 150 160 170 180 190 >>CCDS3950.1 FGF10 gene_id:2255|Hs108|chr5 (208 aa) initn: 238 init1: 205 opt: 270 Z-score: 354.3 bits: 72.1 E(32554): 2.1e-13 Smith-Waterman score: 270; 34.0% identity (65.2% similar) in 141 aa overlap (16-154:70-208) 10 20 30 40 pF1KB6 MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGT .: :. . ::. .. .::.: .: CCDS39 LGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTK--YFLKIEKNGK 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB6 VDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLE :.::. .. . :.... .: : .:. ... ::::. : ::::. :..: . ::.: CCDS39 VSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIE 100 110 120 130 140 150 110 120 130 140 150 pF1KB6 ENHYNTYIS--KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD :: :::: : .: .. .:.:. .:. .:: .:. . . :::. : : CCDS39 ENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS 160 170 180 190 200 155 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:12:54 2016 done: Fri Nov 4 15:12:54 2016 Total Scan time: 1.830 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]