FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6791, 127 aa
1>>>pF1KB6791 127 - 127 aa - 127 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2238+/-0.000398; mu= 11.0073+/- 0.025
mean_var=57.5808+/-11.231, 0's: 0 Z-trim(110.7): 26 B-trim: 165 in 2/52
Lambda= 0.169019
statistics sampled from 19088 (19111) to 19088 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.224), width: 16
Scan time: 4.200
The best scores are: opt bits E(85289)
NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 793 201.5 3.1e-52
NP_001436 (OMIM: 600422) gastrotropin isoform 2 [H ( 128) 337 90.3 9.2e-19
NP_001124430 (OMIM: 600422) gastrotropin isoform 1 ( 177) 337 90.3 1.2e-18
NP_001035532 (OMIM: 600422) gastrotropin isoform 1 ( 177) 337 90.3 1.2e-18
NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 184 53.0 1.7e-07
XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 184 53.0 1.7e-07
NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 184 53.0 1.7e-07
NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 166 48.6 3.5e-06
NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 161 47.4 7.8e-06
NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 154 45.7 2.6e-05
NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 152 45.3 5.1e-05
NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 137 41.6 0.00055
NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 135 41.0 0.00063
NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 133 40.6 0.00089
NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 132 40.3 0.0011
XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 127 39.1 0.0023
NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 123 38.1 0.0055
NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 123 38.1 0.0056
NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 121 37.6 0.0068
>>NP_001434 (OMIM: 134650) fatty acid-binding protein, l (127 aa)
initn: 793 init1: 793 opt: 793 Z-score: 1058.9 bits: 201.5 E(85289): 3.1e-52
Smith-Waterman score: 793; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127)
10 20 30 40 50 60
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVF
70 80 90 100 110 120
pF1KB6 KRISKRI
:::::::
NP_001 KRISKRI
>>NP_001436 (OMIM: 600422) gastrotropin isoform 2 [Homo (128 aa)
initn: 322 init1: 139 opt: 337 Z-score: 457.9 bits: 90.3 E(85289): 9.2e-19
Smith-Waterman score: 337; 36.7% identity (82.0% similar) in 128 aa overlap (1-127:1-127)
10 20 30 40 50
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTIT-AGSKVI
:.:.::....:..:.. ::: .:. ..:.:....: :.:. :.:. : .. .:....
NP_001 MAFTGKFEMESEKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 QNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIV
:.::::.: ...:: :. :..::.:: .:::..: : ....:. :: .... :.: ..
NP_001 TNKFTVGKESNIQTMGGKTFKATVQMEG-GKLVVNFPNYHQTSEIVGDKLVEVSTIGGVT
70 80 90 100 110
120
pF1KB6 FKRISKRI
..:.:::.
NP_001 YERVSKRLA
120
>>NP_001124430 (OMIM: 600422) gastrotropin isoform 1 [Ho (177 aa)
initn: 322 init1: 139 opt: 337 Z-score: 455.6 bits: 90.3 E(85289): 1.2e-18
Smith-Waterman score: 337; 36.7% identity (82.0% similar) in 128 aa overlap (1-127:50-176)
10 20 30
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQ
:.:.::....:..:.. ::: .:. ..:.
NP_001 RAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIE
20 30 40 50 60 70
40 50 60 70 80
pF1KB6 KGKDIKGVSEIVQNGKHFKFTIT-AGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDN
:....: :.:. :.:. : .. .:.... :.::::.: ...:: :. :..::.:: .
NP_001 KARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEG-G
80 90 100 110 120 130
90 100 110 120
pF1KB6 KLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI
:::..: : ....:. :: .... :.: ....:.:::.
NP_001 KLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA
140 150 160 170
>>NP_001035532 (OMIM: 600422) gastrotropin isoform 1 [Ho (177 aa)
initn: 322 init1: 139 opt: 337 Z-score: 455.6 bits: 90.3 E(85289): 1.2e-18
Smith-Waterman score: 337; 36.7% identity (82.0% similar) in 128 aa overlap (1-127:50-176)
10 20 30
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQ
:.:.::....:..:.. ::: .:. ..:.
NP_001 RAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIE
20 30 40 50 60 70
40 50 60 70 80
pF1KB6 KGKDIKGVSEIVQNGKHFKFTIT-AGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDN
:....: :.:. :.:. : .. .:.... :.::::.: ...:: :. :..::.:: .
NP_001 KARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEG-G
80 90 100 110 120 130
90 100 110 120
pF1KB6 KLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI
:::..: : ....:. :: .... :.: ....:.:::.
NP_001 KLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA
140 150 160 170
>>NP_001186652 (OMIM: 180231) cellular retinoic acid-bin (138 aa)
initn: 175 init1: 82 opt: 184 Z-score: 255.7 bits: 53.0 E(85289): 1.7e-07
Smith-Waterman score: 187; 32.4% identity (60.3% similar) in 136 aa overlap (2-126:3-137)
10 20 30 40 50
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEEL--IQKGKDIKGVSEIVQNGKHFKFTITAGSK
.:::.... .:::: ..:..:. : : . : . :: :.: : . .. .
NP_001 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVR
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 VIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKS-------VTEL--NGDI
. . .: :::: : .:. :. :..:. :..::.: : .:. . :: .:..
NP_001 TTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGEL
70 80 90 100 110 120
110 120
pF1KB6 ITNTMTLGDIVFKRISKRI
: ::: :.: :. :
NP_001 IL-TMTADDVVCTRVYVRE
130
>>XP_016855832 (OMIM: 180231) PREDICTED: cellular retino (138 aa)
initn: 175 init1: 82 opt: 184 Z-score: 255.7 bits: 53.0 E(85289): 1.7e-07
Smith-Waterman score: 187; 32.4% identity (60.3% similar) in 136 aa overlap (2-126:3-137)
10 20 30 40 50
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEEL--IQKGKDIKGVSEIVQNGKHFKFTITAGSK
.:::.... .:::: ..:..:. : : . : . :: :.: : . .. .
XP_016 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVR
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 VIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKS-------VTEL--NGDI
. . .: :::: : .:. :. :..:. :..::.: : .:. . :: .:..
XP_016 TTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGEL
70 80 90 100 110 120
110 120
pF1KB6 ITNTMTLGDIVFKRISKRI
: ::: :.: :. :
XP_016 IL-TMTADDVVCTRVYVRE
130
>>NP_001869 (OMIM: 180231) cellular retinoic acid-bindin (138 aa)
initn: 175 init1: 82 opt: 184 Z-score: 255.7 bits: 53.0 E(85289): 1.7e-07
Smith-Waterman score: 187; 32.4% identity (60.3% similar) in 136 aa overlap (2-126:3-137)
10 20 30 40 50
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEEL--IQKGKDIKGVSEIVQNGKHFKFTITAGSK
.:::.... .:::: ..:..:. : : . : . :: :.: : . .. .
NP_001 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVR
10 20 30 40 50 60
60 70 80 90 100
pF1KB6 VIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKS-------VTEL--NGDI
. . .: :::: : .:. :. :..:. :..::.: : .:. . :: .:..
NP_001 TTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGEL
70 80 90 100 110 120
110 120
pF1KB6 ITNTMTLGDIVFKRISKRI
: ::: :.: :. :
NP_001 IL-TMTADDVVCTRVYVRE
130
>>NP_004369 (OMIM: 180230) cellular retinoic acid-bindin (137 aa)
initn: 112 init1: 67 opt: 166 Z-score: 232.0 bits: 48.6 E(85289): 3.5e-06
Smith-Waterman score: 166; 28.4% identity (58.2% similar) in 134 aa overlap (2-126:3-136)
10 20 30 40 50
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEEL--IQKGKDIKGVSEIVQNGKHFKFTITAGSK
.:.: ....:.:::. ..::.:. : . . : :: :.: .: . .. .
NP_004 MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 VIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKS-------VTELNGDIIT
. . .: ::: : ::. :.: .... :..::. : ... . :: .: .
NP_004 TTEINFKVGEGFEEETVDGRKCRSLATWENENKIHCTQTLLEGDGPKTYWTRELANDELI
70 80 90 100 110 120
120
pF1KB6 NTMTLGDIVFKRISKRI
:. :.: :: :
NP_004 LTFGADDVVCTRIYVRE
130
>>NP_001437 (OMIM: 602965) fatty acid-binding protein, b (132 aa)
initn: 133 init1: 133 opt: 161 Z-score: 225.7 bits: 47.4 E(85289): 7.8e-06
Smith-Waterman score: 161; 30.4% identity (57.6% similar) in 125 aa overlap (2-122:4-127)
10 20 30 40 50
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKV
.: . ..: ...::. .:::.:. : :. : . : :.: . . . :
NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 IQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFK----NIKSVTELNGDIITNTMT
. : .::: . : .. :.::.:.:: ::: : . . : :.. .. :.:
NP_001 TEISFQLGEEFDETTADDRNCKSVVSLDGD-KLVHIQKWDGKETNFVREIKDGKMVMTLT
70 80 90 100 110
120
pF1KB6 LGDIVFKRISKRI
.::.: :
NP_001 FGDVVAVRHYEKA
120 130
>>NP_004155 (OMIM: 180280) retinol-binding protein 2 [Ho (134 aa)
initn: 145 init1: 88 opt: 154 Z-score: 216.4 bits: 45.7 E(85289): 2.6e-05
Smith-Waterman score: 154; 28.7% identity (59.7% similar) in 129 aa overlap (4-126:6-133)
10 20 30 40 50
pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKV
.: ....:.::::..:::. . . . . .. : :.: .:: :. .
NP_004 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 IQNEFTVGEECE--LETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTE----LNGDIITNT
. .:::: : . ... ...::..: ::: :: . :. : ..:: .
NP_004 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDV-LVCVQKGEKENRGWKQWIEGDKLYLE
70 80 90 100 110
120
pF1KB6 MTLGDIVFKRISKRI
.: :: : ... :.
NP_004 LTCGDQVCRQVFKKK
120 130
127 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:37:35 2016 done: Sat Nov 5 17:37:36 2016
Total Scan time: 4.200 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]