FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6791, 127 aa 1>>>pF1KB6791 127 - 127 aa - 127 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2238+/-0.000398; mu= 11.0073+/- 0.025 mean_var=57.5808+/-11.231, 0's: 0 Z-trim(110.7): 26 B-trim: 165 in 2/52 Lambda= 0.169019 statistics sampled from 19088 (19111) to 19088 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.224), width: 16 Scan time: 4.200 The best scores are: opt bits E(85289) NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 793 201.5 3.1e-52 NP_001436 (OMIM: 600422) gastrotropin isoform 2 [H ( 128) 337 90.3 9.2e-19 NP_001124430 (OMIM: 600422) gastrotropin isoform 1 ( 177) 337 90.3 1.2e-18 NP_001035532 (OMIM: 600422) gastrotropin isoform 1 ( 177) 337 90.3 1.2e-18 NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 184 53.0 1.7e-07 XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 184 53.0 1.7e-07 NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 184 53.0 1.7e-07 NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 166 48.6 3.5e-06 NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 161 47.4 7.8e-06 NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 154 45.7 2.6e-05 NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 152 45.3 5.1e-05 NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 137 41.6 0.00055 NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 135 41.0 0.00063 NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 133 40.6 0.00089 NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 132 40.3 0.0011 XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 127 39.1 0.0023 NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 123 38.1 0.0055 NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 123 38.1 0.0056 NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 121 37.6 0.0068 >>NP_001434 (OMIM: 134650) fatty acid-binding protein, l (127 aa) initn: 793 init1: 793 opt: 793 Z-score: 1058.9 bits: 201.5 E(85289): 3.1e-52 Smith-Waterman score: 793; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVF 70 80 90 100 110 120 pF1KB6 KRISKRI ::::::: NP_001 KRISKRI >>NP_001436 (OMIM: 600422) gastrotropin isoform 2 [Homo (128 aa) initn: 322 init1: 139 opt: 337 Z-score: 457.9 bits: 90.3 E(85289): 9.2e-19 Smith-Waterman score: 337; 36.7% identity (82.0% similar) in 128 aa overlap (1-127:1-127) 10 20 30 40 50 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTIT-AGSKVI :.:.::....:..:.. ::: .:. ..:.:....: :.:. :.:. : .. .:.... NP_001 MAFTGKFEMESEKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 QNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIV :.::::.: ...:: :. :..::.:: .:::..: : ....:. :: .... :.: .. NP_001 TNKFTVGKESNIQTMGGKTFKATVQMEG-GKLVVNFPNYHQTSEIVGDKLVEVSTIGGVT 70 80 90 100 110 120 pF1KB6 FKRISKRI ..:.:::. NP_001 YERVSKRLA 120 >>NP_001124430 (OMIM: 600422) gastrotropin isoform 1 [Ho (177 aa) initn: 322 init1: 139 opt: 337 Z-score: 455.6 bits: 90.3 E(85289): 1.2e-18 Smith-Waterman score: 337; 36.7% identity (82.0% similar) in 128 aa overlap (1-127:50-176) 10 20 30 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQ :.:.::....:..:.. ::: .:. ..:. NP_001 RAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIE 20 30 40 50 60 70 40 50 60 70 80 pF1KB6 KGKDIKGVSEIVQNGKHFKFTIT-AGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDN :....: :.:. :.:. : .. .:.... :.::::.: ...:: :. :..::.:: . NP_001 KARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEG-G 80 90 100 110 120 130 90 100 110 120 pF1KB6 KLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI :::..: : ....:. :: .... :.: ....:.:::. NP_001 KLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA 140 150 160 170 >>NP_001035532 (OMIM: 600422) gastrotropin isoform 1 [Ho (177 aa) initn: 322 init1: 139 opt: 337 Z-score: 455.6 bits: 90.3 E(85289): 1.2e-18 Smith-Waterman score: 337; 36.7% identity (82.0% similar) in 128 aa overlap (1-127:50-176) 10 20 30 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQ :.:.::....:..:.. ::: .:. ..:. NP_001 RAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIE 20 30 40 50 60 70 40 50 60 70 80 pF1KB6 KGKDIKGVSEIVQNGKHFKFTIT-AGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDN :....: :.:. :.:. : .. .:.... :.::::.: ...:: :. :..::.:: . NP_001 KARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEG-G 80 90 100 110 120 130 90 100 110 120 pF1KB6 KLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI :::..: : ....:. :: .... :.: ....:.:::. NP_001 KLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA 140 150 160 170 >>NP_001186652 (OMIM: 180231) cellular retinoic acid-bin (138 aa) initn: 175 init1: 82 opt: 184 Z-score: 255.7 bits: 53.0 E(85289): 1.7e-07 Smith-Waterman score: 187; 32.4% identity (60.3% similar) in 136 aa overlap (2-126:3-137) 10 20 30 40 50 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEEL--IQKGKDIKGVSEIVQNGKHFKFTITAGSK .:::.... .:::: ..:..:. : : . : . :: :.: : . .. . NP_001 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVR 10 20 30 40 50 60 60 70 80 90 100 pF1KB6 VIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKS-------VTEL--NGDI . . .: :::: : .:. :. :..:. :..::.: : .:. . :: .:.. NP_001 TTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGEL 70 80 90 100 110 120 110 120 pF1KB6 ITNTMTLGDIVFKRISKRI : ::: :.: :. : NP_001 IL-TMTADDVVCTRVYVRE 130 >>XP_016855832 (OMIM: 180231) PREDICTED: cellular retino (138 aa) initn: 175 init1: 82 opt: 184 Z-score: 255.7 bits: 53.0 E(85289): 1.7e-07 Smith-Waterman score: 187; 32.4% identity (60.3% similar) in 136 aa overlap (2-126:3-137) 10 20 30 40 50 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEEL--IQKGKDIKGVSEIVQNGKHFKFTITAGSK .:::.... .:::: ..:..:. : : . : . :: :.: : . .. . XP_016 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVR 10 20 30 40 50 60 60 70 80 90 100 pF1KB6 VIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKS-------VTEL--NGDI . . .: :::: : .:. :. :..:. :..::.: : .:. . :: .:.. XP_016 TTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGEL 70 80 90 100 110 120 110 120 pF1KB6 ITNTMTLGDIVFKRISKRI : ::: :.: :. : XP_016 IL-TMTADDVVCTRVYVRE 130 >>NP_001869 (OMIM: 180231) cellular retinoic acid-bindin (138 aa) initn: 175 init1: 82 opt: 184 Z-score: 255.7 bits: 53.0 E(85289): 1.7e-07 Smith-Waterman score: 187; 32.4% identity (60.3% similar) in 136 aa overlap (2-126:3-137) 10 20 30 40 50 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEEL--IQKGKDIKGVSEIVQNGKHFKFTITAGSK .:::.... .:::: ..:..:. : : . : . :: :.: : . .. . NP_001 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVR 10 20 30 40 50 60 60 70 80 90 100 pF1KB6 VIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKS-------VTEL--NGDI . . .: :::: : .:. :. :..:. :..::.: : .:. . :: .:.. NP_001 TTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGEL 70 80 90 100 110 120 110 120 pF1KB6 ITNTMTLGDIVFKRISKRI : ::: :.: :. : NP_001 IL-TMTADDVVCTRVYVRE 130 >>NP_004369 (OMIM: 180230) cellular retinoic acid-bindin (137 aa) initn: 112 init1: 67 opt: 166 Z-score: 232.0 bits: 48.6 E(85289): 3.5e-06 Smith-Waterman score: 166; 28.4% identity (58.2% similar) in 134 aa overlap (2-126:3-136) 10 20 30 40 50 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEEL--IQKGKDIKGVSEIVQNGKHFKFTITAGSK .:.: ....:.:::. ..::.:. : . . : :: :.: .: . .. . NP_004 MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 VIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKS-------VTELNGDIIT . . .: ::: : ::. :.: .... :..::. : ... . :: .: . NP_004 TTEINFKVGEGFEEETVDGRKCRSLATWENENKIHCTQTLLEGDGPKTYWTRELANDELI 70 80 90 100 110 120 120 pF1KB6 NTMTLGDIVFKRISKRI :. :.: :: : NP_004 LTFGADDVVCTRIYVRE 130 >>NP_001437 (OMIM: 602965) fatty acid-binding protein, b (132 aa) initn: 133 init1: 133 opt: 161 Z-score: 225.7 bits: 47.4 E(85289): 7.8e-06 Smith-Waterman score: 161; 30.4% identity (57.6% similar) in 125 aa overlap (2-122:4-127) 10 20 30 40 50 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKV .: . ..: ...::. .:::.:. : :. : . : :.: . . . : NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 IQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFK----NIKSVTELNGDIITNTMT . : .::: . : .. :.::.:.:: ::: : . . : :.. .. :.: NP_001 TEISFQLGEEFDETTADDRNCKSVVSLDGD-KLVHIQKWDGKETNFVREIKDGKMVMTLT 70 80 90 100 110 120 pF1KB6 LGDIVFKRISKRI .::.: : NP_001 FGDVVAVRHYEKA 120 130 >>NP_004155 (OMIM: 180280) retinol-binding protein 2 [Ho (134 aa) initn: 145 init1: 88 opt: 154 Z-score: 216.4 bits: 45.7 E(85289): 2.6e-05 Smith-Waterman score: 154; 28.7% identity (59.7% similar) in 129 aa overlap (4-126:6-133) 10 20 30 40 50 pF1KB6 MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKV .: ....:.::::..:::. . . . . .. : :.: .:: :. . NP_004 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVRLTQTKVIDQDGDNFKTKTTSTFRN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 IQNEFTVGEECE--LETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTE----LNGDIITNT . .:::: : . ... ...::..: ::: :: . :. : ..:: . NP_004 YDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDV-LVCVQKGEKENRGWKQWIEGDKLYLE 70 80 90 100 110 120 pF1KB6 MTLGDIVFKRISKRI .: :: : ... :. NP_004 LTCGDQVCRQVFKKK 120 130 127 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:37:35 2016 done: Sat Nov 5 17:37:36 2016 Total Scan time: 4.200 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]