FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6792, 155 aa 1>>>pF1KB6792 155 - 155 aa - 155 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2279+/-0.000674; mu= 12.0475+/- 0.041 mean_var=55.8541+/-11.508, 0's: 0 Z-trim(109.4): 19 B-trim: 172 in 1/51 Lambda= 0.171612 statistics sampled from 10832 (10851) to 10832 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.333), width: 16 Scan time: 1.850 The best scores are: opt bits E(32554) CCDS2111.1 IL36RN gene_id:26525|Hs108|chr2 ( 155) 1060 269.9 4.4e-73 CCDS2115.1 IL1RN gene_id:3557|Hs108|chr2 ( 143) 414 109.9 5.8e-25 CCDS2113.1 IL1RN gene_id:3557|Hs108|chr2 ( 159) 414 110.0 6.3e-25 CCDS46396.1 IL1RN gene_id:3557|Hs108|chr2 ( 177) 414 110.0 7e-25 CCDS2114.1 IL1RN gene_id:3557|Hs108|chr2 ( 180) 414 110.0 7.1e-25 CCDS2112.1 IL1F10 gene_id:84639|Hs108|chr2 ( 152) 365 97.8 2.7e-21 CCDS2110.1 IL36B gene_id:27177|Hs108|chr2 ( 157) 260 71.8 1.9e-13 CCDS42734.1 IL36A gene_id:27179|Hs108|chr2 ( 158) 245 68.1 2.5e-12 CCDS62992.1 IL36G gene_id:56300|Hs108|chr2 ( 134) 230 64.4 2.8e-11 CCDS2108.1 IL36G gene_id:56300|Hs108|chr2 ( 169) 230 64.4 3.5e-11 CCDS2107.1 IL37 gene_id:27178|Hs108|chr2 ( 192) 229 64.2 4.6e-11 CCDS2104.1 IL37 gene_id:27178|Hs108|chr2 ( 197) 229 64.2 4.7e-11 CCDS2103.1 IL37 gene_id:27178|Hs108|chr2 ( 218) 229 64.2 5.2e-11 >>CCDS2111.1 IL36RN gene_id:26525|Hs108|chr2 (155 aa) initn: 1060 init1: 1060 opt: 1060 Z-score: 1425.5 bits: 269.9 E(32554): 4.4e-73 Smith-Waterman score: 1060; 100.0% identity (100.0% similar) in 155 aa overlap (1-155:1-155) 10 20 30 40 50 60 pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 VQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWF 70 80 90 100 110 120 130 140 150 pF1KB6 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD ::::::::::::::::::::::::::::::::::: CCDS21 LCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD 130 140 150 >>CCDS2115.1 IL1RN gene_id:3557|Hs108|chr2 (143 aa) initn: 410 init1: 242 opt: 414 Z-score: 561.7 bits: 109.9 E(32554): 5.8e-25 Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:4-141) 10 20 30 40 50 pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP--VI ::. : :..::.::::.:: :.. .: :.:.::: . : .. CCDS21 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP-------IEPHALF 10 20 30 40 60 70 80 90 100 110 pF1KB6 LGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYP ::..::..:::: :.: : :: ::: .: . :..: :.: : : : :.:::::: : CCDS21 LGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACP 50 60 70 80 90 100 120 130 140 150 pF1KB6 GWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD ::::::. :::::: ::..:..: . .: ::::. CCDS21 GWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE 110 120 130 140 >>CCDS2113.1 IL1RN gene_id:3557|Hs108|chr2 (159 aa) initn: 410 init1: 242 opt: 414 Z-score: 560.9 bits: 110.0 E(32554): 6.3e-25 Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:20-157) 10 20 30 40 pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRW ::. : :..::.::::.:: :.. .: :.:.::: CCDS21 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP--- 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 LDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMG . : ..::..::..:::: :.: : :: ::: .: . :..: :.: : : : CCDS21 ----IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSG 60 70 80 90 100 110 110 120 130 140 150 pF1KB6 LTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD :.:::::: :::::::. :::::: ::..:..: . .: ::::. CCDS21 PTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE 120 130 140 150 >>CCDS46396.1 IL1RN gene_id:3557|Hs108|chr2 (177 aa) initn: 410 init1: 242 opt: 414 Z-score: 560.2 bits: 110.0 E(32554): 7e-25 Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:38-175) 10 20 30 pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIK ::. : :..::.::::.:: :.. .: CCDS46 RSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNL 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 GEEISVVPNRWLDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKES :.:.::: . : ..::..::..:::: :.: : :: ::: .: . :.. CCDS46 EEKIDVVP-------IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 KSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD : :.: : : : :.:::::: :::::::. :::::: ::..:..: . .: ::::. CCDS46 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE 130 140 150 160 170 >>CCDS2114.1 IL1RN gene_id:3557|Hs108|chr2 (180 aa) initn: 410 init1: 242 opt: 414 Z-score: 560.1 bits: 110.0 E(32554): 7.1e-25 Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (9-153:41-178) 10 20 30 pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIK ::. : :..::.::::.:: :.. .: CCDS21 GGGGGEGEDNADSKETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNL 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 GEEISVVPNRWLDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKES :.:.::: . : ..::..::..:::: :.: : :: ::: .: . :.. CCDS21 EEKIDVVP-------IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 KSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD : :.: : : : :.:::::: :::::::. :::::: ::..:..: . .: ::::. CCDS21 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE 130 140 150 160 170 180 >>CCDS2112.1 IL1F10 gene_id:84639|Hs108|chr2 (152 aa) initn: 342 init1: 210 opt: 365 Z-score: 495.7 bits: 97.8 E(32554): 2.7e-21 Smith-Waterman score: 365; 43.8% identity (68.8% similar) in 144 aa overlap (11-153:12-150) 10 20 30 40 50 pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVIL .: . :.:: ...:::.: : . .:.: ..::: : . :..: CCDS21 MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCC-AEKICILPNRGLARTKVPIFL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GVQGGSQCLSCGVGQE-PTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPG :.::::.::.: .: :.: :: ::: ::: :..:. :::.. . : . .:.::.:: CCDS21 GIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPG 60 70 80 90 100 110 120 130 140 150 pF1KB6 WFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD :::: : .:::.::. : .. : :::.: CCDS21 WFLCGPAEPQQPVQLTKESEPSAR----TKFYFEQSW 120 130 140 150 >>CCDS2110.1 IL36B gene_id:27177|Hs108|chr2 (157 aa) initn: 224 init1: 187 opt: 260 Z-score: 355.0 bits: 71.8 E(32554): 1.9e-13 Smith-Waterman score: 260; 35.7% identity (59.7% similar) in 154 aa overlap (9-155:12-157) 10 20 30 40 50 pF1KB6 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSP- . ..:: : : .:.:.:. : .. :: . .. : :. .: CCDS21 MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPL--SRSIKPVTLHLIACR--DTEFSDK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 -----VILGVQGGSQCLSCGVGQ-EPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSS : ::..: . :: :. : .::: :. :::.::. : .: : :.. : :: CCDS21 EKGNMVYLGIKGKDLCLFCAEIQGKPTLQLKEKNIMDLYVEKKAQKPFLFFHNKEGSTSV 60 70 80 90 100 110 120 130 140 150 pF1KB6 FESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD :.:..:::::. : . ::. ::. : : : :.::... . CCDS21 FQSVSYPGWFIATSTTSGQPIFLTK--ERGITNN--TNFYLDSVE 120 130 140 150 >>CCDS42734.1 IL36A gene_id:27179|Hs108|chr2 (158 aa) initn: 224 init1: 192 opt: 245 Z-score: 334.9 bits: 68.1 E(32554): 2.5e-12 Smith-Waterman score: 245; 44.8% identity (68.8% similar) in 96 aa overlap (55-149:61-152) 30 40 50 60 70 80 pF1KB6 QLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILGVQGGSQCLSCG-VGQEPTLTLEPV .:. ::..: . :: :. ::..::: :. CCDS42 IAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEK 40 50 60 70 80 90 90 100 110 120 130 140 pF1KB6 NIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWN .::.:: . ::: ::. . : .:.:::.:.::::. . :. :. ::: : : . CCDS42 DIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQ--ELG--K 100 110 120 130 140 150 pF1KB6 APITDFYFQQCD : ::: CCDS42 ANTTDFGLTMLF 150 >>CCDS62992.1 IL36G gene_id:56300|Hs108|chr2 (134 aa) initn: 217 init1: 160 opt: 230 Z-score: 315.9 bits: 64.4 E(32554): 2.8e-11 Smith-Waterman score: 230; 45.0% identity (67.5% similar) in 80 aa overlap (56-134:39-117) 30 40 50 60 70 80 pF1KB6 LLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILGVQGGSQCLSC-GVGQEPTLTLEPVN :. ::.:. .:: : ::..::: :. . CCDS62 DGGGRAVYQSITVAVITCKYPEALEQGRGDPIYLGIQNPEMCLYCEKVGEQPTLQLKEQK 10 20 30 40 50 60 90 100 110 120 130 140 pF1KB6 IMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNA ::.:: . : : ::: : ::..::.:.: ::. . . :::. :: CCDS62 IMDLYGQPEPVKPFLFYRAKTGRTSTLESVAFPDWFIAS-SKRDQPIILTSELGKSYNTA 70 80 90 100 110 120 150 pF1KB6 PITDFYFQQCD CCDS62 FELNIND 130 >>CCDS2108.1 IL36G gene_id:56300|Hs108|chr2 (169 aa) initn: 217 init1: 160 opt: 230 Z-score: 314.3 bits: 64.4 E(32554): 3.5e-11 Smith-Waterman score: 230; 45.0% identity (67.5% similar) in 80 aa overlap (56-134:74-152) 30 40 50 60 70 80 pF1KB6 LLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILGVQGGSQCLSC-GVGQEPTLTLEPVN :. ::.:. .:: : ::..::: :. . CCDS21 AVPRSDSVTPVTVAVITCKYPEALEQGRGDPIYLGIQNPEMCLYCEKVGEQPTLQLKEQK 50 60 70 80 90 100 90 100 110 120 130 140 pF1KB6 IMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNA ::.:: . : : ::: : ::..::.:.: ::. . . :::. :: CCDS21 IMDLYGQPEPVKPFLFYRAKTGRTSTLESVAFPDWFIAS-SKRDQPIILTSELGKSYNTA 110 120 130 140 150 160 150 pF1KB6 PITDFYFQQCD CCDS21 FELNIND 155 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:18:11 2016 done: Sat Nov 5 18:18:11 2016 Total Scan time: 1.850 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]