FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6793, 127 aa 1>>>pF1KB6793 127 - 127 aa - 127 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6058+/-0.000777; mu= 10.2661+/- 0.047 mean_var=72.7934+/-13.840, 0's: 0 Z-trim(108.4): 12 B-trim: 99 in 1/51 Lambda= 0.150324 statistics sampled from 10175 (10183) to 10175 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.313), width: 16 Scan time: 1.390 The best scores are: opt bits E(32554) CCDS7380.1 SNCG gene_id:6623|Hs108|chr10 ( 127) 756 172.3 7e-44 CCDS3634.1 SNCA gene_id:6622|Hs108|chr4 ( 140) 388 92.5 8e-20 CCDS43252.1 SNCA gene_id:6622|Hs108|chr4 ( 112) 383 91.4 1.4e-19 CCDS4406.1 SNCB gene_id:6620|Hs108|chr5 ( 134) 342 82.6 7.8e-17 CCDS81483.1 SNCG gene_id:6623|Hs108|chr10 ( 126) 325 78.9 9.5e-16 >>CCDS7380.1 SNCG gene_id:6623|Hs108|chr10 (127 aa) initn: 756 init1: 756 opt: 756 Z-score: 901.3 bits: 172.3 E(32554): 7e-44 Smith-Waterman score: 756; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KB6 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAE 70 80 90 100 110 120 pF1KB6 EAQSGGD ::::::: CCDS73 EAQSGGD >>CCDS3634.1 SNCA gene_id:6622|Hs108|chr4 (140 aa) initn: 569 init1: 381 opt: 388 Z-score: 469.3 bits: 92.5 E(32554): 8e-20 Smith-Waterman score: 388; 62.7% identity (88.2% similar) in 110 aa overlap (1-107:1-110) 10 20 30 40 50 60 pF1KB6 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTK :::: ::.: ::::::.:.:::::::.::: ::::::.:::.::::.::..:..:::::: CCDS36 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 EQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDL---RPSAPQQEGEASKEKEE ::.. :. :::..:..:: :::: : .::...: :.:..: . .:::. CCDS36 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP 70 80 90 100 110 120 120 pF1KB6 VAEEAQSGGD CCDS36 DNEAYEMPSEEGYQDYEPEA 130 140 >>CCDS43252.1 SNCA gene_id:6622|Hs108|chr4 (112 aa) initn: 481 init1: 381 opt: 383 Z-score: 464.9 bits: 91.4 E(32554): 1.4e-19 Smith-Waterman score: 383; 62.5% identity (86.6% similar) in 112 aa overlap (1-111:1-112) 10 20 30 40 50 60 pF1KB6 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTK :::: ::.: ::::::.:.:::::::.::: ::::::.:::.::::.::..:..:::::: CCDS43 MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 EQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQ-EGEASKEKEEVA ::.. :. :::..:..:: :::: : .::...: :.:..: . :. : :: CCDS43 EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKEGYQDYEPEA 70 80 90 100 110 120 pF1KB6 EEAQSGGD >>CCDS4406.1 SNCB gene_id:6620|Hs108|chr5 (134 aa) initn: 570 init1: 341 opt: 342 Z-score: 415.7 bits: 82.6 E(32554): 7.8e-17 Smith-Waterman score: 362; 54.5% identity (73.5% similar) in 132 aa overlap (1-127:1-121) 10 20 30 40 50 60 pF1KB6 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTK :::: ::.:.::::::.:.::::::::::::::::::.:::.::.:.:::.:.::::::: CCDS44 MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTREGVVQGVASVAEKTK 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 EQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKE----DLRPSAPQQEGEASKEKE :::. .. :: :. : :::...:.:..: ::.: ::. : CCDS44 EQASHLGGAVFSG-----------AGNIAAATGLVKREEFPTDLKPEEVAQEAAEEPLIE 70 80 90 100 120 pF1KB6 EVAE-EAQSGGD . : :..: : CCDS44 PLMEPEGESYEDPPQEEYQEYEPEA 110 120 130 >>CCDS81483.1 SNCG gene_id:6623|Hs108|chr10 (126 aa) initn: 335 init1: 325 opt: 325 Z-score: 396.2 bits: 78.9 E(32554): 9.5e-16 Smith-Waterman score: 325; 100.0% identity (100.0% similar) in 54 aa overlap (1-54:1-54) 10 20 30 40 50 60 pF1KB6 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTK :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSGLPWGW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAE CCDS81 GWGGGQPVSSHSGREDQGAGQRRERGCGEQRQHCGHQDRGGGGEHRGHLRGGAQGGLEAI 70 80 90 100 110 120 127 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:01:33 2016 done: Sat Nov 5 00:01:34 2016 Total Scan time: 1.390 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]