FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6795, 128 aa 1>>>pF1KB6795 128 - 128 aa - 128 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0390+/-0.000303; mu= 13.3437+/- 0.019 mean_var=76.7168+/-14.958, 0's: 0 Z-trim(118.1): 123 B-trim: 0 in 0/54 Lambda= 0.146430 statistics sampled from 30573 (30715) to 30573 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.36), width: 16 Scan time: 4.370 The best scores are: opt bits E(85289) NP_002092 (OMIM: 110750,611162,616089) glycophorin ( 128) 846 187.0 6.9e-48 XP_006712523 (OMIM: 110750,611162,616089) PREDICTE ( 122) 727 161.9 2.5e-40 NP_001243513 (OMIM: 110750,611162,616089) glycopho ( 107) 688 153.6 6.8e-38 NP_058131 (OMIM: 110750,611162,616089) glycophorin ( 109) 609 136.9 7.2e-33 NP_054860 (OMIM: 604569,610042,612100) contactin-a (1331) 269 66.0 1.9e-10 XP_016872949 (OMIM: 605686) PREDICTED: cell adhesi ( 295) 218 54.7 1.1e-07 NP_001287973 (OMIM: 605686) cell adhesion molecule ( 453) 220 55.3 1.1e-07 XP_016872947 (OMIM: 605686) PREDICTED: cell adhesi ( 402) 218 54.8 1.4e-07 NP_055148 (OMIM: 605686) cell adhesion molecule 1 ( 442) 218 54.8 1.5e-07 NP_001243431 (OMIM: 609938) cell adhesion molecule ( 327) 204 51.8 9.3e-07 NP_001243432 (OMIM: 609938) cell adhesion molecule ( 327) 204 51.8 9.3e-07 XP_006713144 (OMIM: 609938) PREDICTED: cell adhesi ( 435) 204 51.9 1.1e-06 NP_001161146 (OMIM: 609938) cell adhesion molecule ( 435) 204 51.9 1.1e-06 NP_694854 (OMIM: 609938) cell adhesion molecule 2 ( 437) 204 51.9 1.1e-06 XP_016861551 (OMIM: 609938) PREDICTED: cell adhesi ( 449) 204 51.9 1.2e-06 XP_005271551 (OMIM: 605686) PREDICTED: cell adhesi ( 425) 196 50.2 3.6e-06 XP_016872950 (OMIM: 605686) PREDICTED: cell adhesi ( 267) 193 49.4 4e-06 XP_016872948 (OMIM: 605686) PREDICTED: cell adhesi ( 324) 193 49.4 4.6e-06 NP_001091987 (OMIM: 605686) cell adhesion molecule ( 414) 193 49.5 5.5e-06 NP_001287974 (OMIM: 605686) cell adhesion molecule ( 443) 193 49.6 5.8e-06 NP_001287972 (OMIM: 605686) cell adhesion molecule ( 471) 193 49.6 6.1e-06 XP_016872946 (OMIM: 605686) PREDICTED: cell adhesi ( 477) 193 49.6 6.1e-06 NP_001243433 (OMIM: 609938) cell adhesion molecule ( 287) 184 47.5 1.6e-05 NP_001243434 (OMIM: 609938) cell adhesion molecule ( 287) 184 47.5 1.6e-05 XP_016858805 (OMIM: 610519) PREDICTED: contactin-a (1227) 191 49.5 1.7e-05 NP_570129 (OMIM: 610519) contactin-associated prot (1306) 191 49.6 1.7e-05 XP_006712321 (OMIM: 610519) PREDICTED: contactin-a (1307) 191 49.6 1.7e-05 XP_006713145 (OMIM: 609938) PREDICTED: cell adhesi ( 395) 184 47.6 2e-05 XP_016861552 (OMIM: 609938) PREDICTED: cell adhesi ( 397) 184 47.6 2e-05 NP_001161147 (OMIM: 609938) cell adhesion molecule ( 404) 184 47.6 2e-05 NP_001333439 (OMIM: 609743) cell adhesion molecule ( 352) 183 47.4 2.1e-05 NP_001120645 (OMIM: 609743) cell adhesion molecule ( 398) 183 47.4 2.3e-05 NP_067012 (OMIM: 609743) cell adhesion molecule 3 ( 432) 183 47.4 2.5e-05 NP_620063 (OMIM: 600566) neurexin-2-beta isoform b ( 666) 165 43.8 0.00047 NP_001309116 (OMIM: 610518) contactin-associated p ( 836) 166 44.1 0.00048 NP_001309120 (OMIM: 610518) contactin-associated p ( 999) 166 44.2 0.00055 XP_016879294 (OMIM: 610518) PREDICTED: contactin-a ( 999) 166 44.2 0.00055 NP_001309109 (OMIM: 610518) contactin-associated p (1179) 166 44.2 0.00062 XP_016874066 (OMIM: 600566) PREDICTED: neurexin-2- ( 974) 165 43.9 0.00063 XP_011543687 (OMIM: 600566) PREDICTED: neurexin-2- ( 977) 165 43.9 0.00063 NP_001309118 (OMIM: 610518) contactin-associated p (1220) 166 44.2 0.00064 NP_001309108 (OMIM: 610518) contactin-associated p (1228) 166 44.2 0.00064 NP_620481 (OMIM: 610518) contactin-associated prot (1235) 166 44.2 0.00065 NP_001309107 (OMIM: 610518) contactin-associated p (1258) 166 44.3 0.00065 NP_001309119 (OMIM: 610518) contactin-associated p (1260) 166 44.3 0.00066 NP_001309117 (OMIM: 610518) contactin-associated p (1273) 166 44.3 0.00066 XP_011521705 (OMIM: 610518) PREDICTED: contactin-a (1283) 166 44.3 0.00066 NP_001309110 (OMIM: 610518) contactin-associated p (1307) 166 44.3 0.00067 NP_207837 (OMIM: 610518) contactin-associated prot (1308) 166 44.3 0.00067 XP_016874065 (OMIM: 600566) PREDICTED: neurexin-2- (1296) 165 44.1 0.00077 >>NP_002092 (OMIM: 110750,611162,616089) glycophorin-C i (128 aa) initn: 846 init1: 846 opt: 846 Z-score: 980.7 bits: 187.0 E(85289): 6.9e-48 Smith-Waterman score: 846; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGD 70 80 90 100 110 120 pF1KB6 SSRKEYFI :::::::: NP_002 SSRKEYFI >>XP_006712523 (OMIM: 110750,611162,616089) PREDICTED: g (122 aa) initn: 727 init1: 727 opt: 727 Z-score: 845.1 bits: 161.9 E(85289): 2.5e-40 Smith-Waterman score: 727; 97.4% identity (98.3% similar) in 115 aa overlap (14-128:8-122) 10 20 30 40 50 60 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIV : .::::::::::::::::::::::::::::::::::::::::::: XP_006 MLTKPQELPRQPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGD 60 70 80 90 100 110 pF1KB6 SSRKEYFI :::::::: XP_006 SSRKEYFI 120 >>NP_001243513 (OMIM: 110750,611162,616089) glycophorin- (107 aa) initn: 688 init1: 688 opt: 688 Z-score: 801.3 bits: 153.6 E(85289): 6.8e-38 Smith-Waterman score: 688; 100.0% identity (100.0% similar) in 107 aa overlap (22-128:1-107) 10 20 30 40 50 60 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIV ::::::::::::::::::::::::::::::::::::::: NP_001 MASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIV 10 20 30 70 80 90 100 110 120 pF1KB6 VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGD 40 50 60 70 80 90 pF1KB6 SSRKEYFI :::::::: NP_001 SSRKEYFI 100 >>NP_058131 (OMIM: 110750,611162,616089) glycophorin-C i (109 aa) initn: 609 init1: 609 opt: 609 Z-score: 711.0 bits: 136.9 E(85289): 7.2e-33 Smith-Waterman score: 677; 85.2% identity (85.2% similar) in 128 aa overlap (1-128:1-109) 10 20 30 40 50 60 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIV :::::::::::::::::::::: ::::::::::::::::::: NP_058 MWSTRSPNSTAWPLSLEPDPGM-------------------SGWPDGRMETSTPTIMDIV 10 20 30 40 70 80 90 100 110 120 pF1KB6 VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_058 VIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGD 50 60 70 80 90 100 pF1KB6 SSRKEYFI :::::::: NP_058 SSRKEYFI >>NP_054860 (OMIM: 604569,610042,612100) contactin-assoc (1331 aa) initn: 230 init1: 199 opt: 269 Z-score: 308.5 bits: 66.0 E(85289): 1.9e-10 Smith-Waterman score: 269; 40.2% identity (65.6% similar) in 122 aa overlap (8-128:1213-1331) 10 20 30 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEP : : ::.: : :.::. : . NP_054 QFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSP---MSSATDPWHLDHLDSA 1190 1200 1210 1220 1230 40 50 60 70 80 90 pF1KB6 DPGMSGWPDGRMETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAK . . : . . . . ..:.::::.: .... : ..:::.:::::::::::: NP_054 SADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAK 1240 1250 1260 1270 1280 1290 100 110 120 pF1KB6 GTEFAESADAA-LQGDPALQDAGDSSRKEYFI :.: ::::::: ...:: . .. : :.::..: NP_054 GAESAESADAAIMNNDPNFTETIDESKKEWLI 1300 1310 1320 1330 >>XP_016872949 (OMIM: 605686) PREDICTED: cell adhesion m (295 aa) initn: 223 init1: 168 opt: 218 Z-score: 258.9 bits: 54.7 E(85289): 1.1e-07 Smith-Waterman score: 218; 37.6% identity (68.4% similar) in 117 aa overlap (13-128:186-295) 10 20 30 40 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMS : . : : ....:: :::: .. XP_016 LNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTI------LT 160 170 180 190 200 50 60 70 80 90 100 pF1KB6 GWPDGRM-ETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEF :.: : .. .: .::.::.:.:..... ::... ::. :::::: :.::::.. XP_016 IITDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADD 210 220 230 240 250 260 110 120 pF1KB6 AESADAALQGDPALQDAGDSSRKEYFI : .::.:. . . :. .. .::::: XP_016 AADADTAIINAEGGQNNSEE-KKEYFI 270 280 290 >>NP_001287973 (OMIM: 605686) cell adhesion molecule 1 i (453 aa) initn: 216 init1: 161 opt: 220 Z-score: 258.7 bits: 55.3 E(85289): 1.1e-07 Smith-Waterman score: 220; 37.7% identity (66.4% similar) in 122 aa overlap (13-128:333-453) 10 20 30 40 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAE--PDPG : . : : ....:: :::: : NP_001 LNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDTT 310 320 330 340 350 360 50 60 70 80 90 pF1KB6 MSGWP---DGRM-ETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEA . : :.: : .. .: .::.::.:.:..... ::... ::. :::::: :.:: NP_001 ATTEPAVHDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEA 370 380 390 400 410 420 100 110 120 pF1KB6 KGTEFAESADAALQGDPALQDAGDSSRKEYFI ::.. : .::.:. . . :. .. .::::: NP_001 KGADDAADADTAIINAEGGQNNSEE-KKEYFI 430 440 450 >>XP_016872947 (OMIM: 605686) PREDICTED: cell adhesion m (402 aa) initn: 223 init1: 168 opt: 218 Z-score: 257.1 bits: 54.8 E(85289): 1.4e-07 Smith-Waterman score: 218; 37.6% identity (68.4% similar) in 117 aa overlap (13-128:293-402) 10 20 30 40 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMS : . : : ....:: :::: .. XP_016 LNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTI------LT 270 280 290 300 310 50 60 70 80 90 100 pF1KB6 GWPDGRM-ETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEF :.: : .. .: .::.::.:.:..... ::... ::. :::::: :.::::.. XP_016 IITDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADD 320 330 340 350 360 370 110 120 pF1KB6 AESADAALQGDPALQDAGDSSRKEYFI : .::.:. . . :. .. .::::: XP_016 AADADTAIINAEGGQNNSEE-KKEYFI 380 390 400 >>NP_055148 (OMIM: 605686) cell adhesion molecule 1 isof (442 aa) initn: 223 init1: 168 opt: 218 Z-score: 256.6 bits: 54.8 E(85289): 1.5e-07 Smith-Waterman score: 218; 37.6% identity (68.4% similar) in 117 aa overlap (13-128:333-442) 10 20 30 40 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMS : . : : ....:: :::: .. NP_055 LNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTI------LT 310 320 330 340 350 50 60 70 80 90 100 pF1KB6 GWPDGRM-ETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEF :.: : .. .: .::.::.:.:..... ::... ::. :::::: :.::::.. NP_055 IITDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADD 360 370 380 390 400 410 110 120 pF1KB6 AESADAALQGDPALQDAGDSSRKEYFI : .::.:. . . :. .. .::::: NP_055 AADADTAIINAEGGQNNSEE-KKEYFI 420 430 440 >>NP_001243431 (OMIM: 609938) cell adhesion molecule 2 i (327 aa) initn: 160 init1: 119 opt: 204 Z-score: 242.3 bits: 51.8 E(85289): 9.3e-07 Smith-Waterman score: 204; 36.3% identity (63.7% similar) in 124 aa overlap (7-128:209-327) 10 20 30 pF1KB6 MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAE :: : : .. :. :...::. :: NP_001 NKTDNGTYRCEATNTIGQSSAEYVLIVHDVPN-TLLPTTIIPSLTTATVTTTVAITTSPT 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB6 PDPGMSGW--PDGRMETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTN . :. :.. . : : ..:.:..:.:..: . .:.. ::. :::::: :: NP_001 TSATTSSIRDPNALAGQNGP---DHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTYLTN 240 250 260 270 280 290 100 110 120 pF1KB6 EAKGTEFAESADAALQGDPALQDAGDSSRKEYFI ::::.: : .::.:. . . : .. .::::: NP_001 EAKGAEDAPDADTAIINAEGSQVNAEE-KKEYFI 300 310 320 128 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:02:08 2016 done: Sat Nov 5 00:02:09 2016 Total Scan time: 4.370 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]