FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6802, 184 aa 1>>>pF1KB6802 184 - 184 aa - 184 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8810+/-0.000804; mu= 9.3776+/- 0.048 mean_var=68.5555+/-13.275, 0's: 0 Z-trim(108.0): 56 B-trim: 0 in 0/52 Lambda= 0.154901 statistics sampled from 9876 (9933) to 9876 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.305), width: 16 Scan time: 1.870 The best scores are: opt bits E(32554) CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 ( 184) 1250 288.0 2.2e-78 CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 ( 205) 1146 264.8 2.4e-71 CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 686 162.0 2.4e-40 CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 643 152.4 1.9e-37 CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 ( 295) 572 136.5 1.4e-32 CCDS9033.1 DUSP6 gene_id:1848|Hs108|chr12 ( 381) 320 80.2 1.6e-15 CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX ( 384) 320 80.2 1.6e-15 CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 ( 482) 321 80.5 1.7e-15 CCDS33766.2 DUSP7 gene_id:1849|Hs108|chr3 ( 419) 312 78.5 6e-15 CCDS9711.1 STYX gene_id:6815|Hs108|chr14 ( 223) 307 77.3 7.3e-15 CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 ( 659) 304 76.7 3.1e-14 CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 ( 625) 299 75.6 6.5e-14 CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 289 73.3 1.9e-13 CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 ( 211) 282 71.7 3.3e-13 CCDS55882.1 SSH1 gene_id:54434|Hs108|chr12 ( 692) 286 72.7 5.3e-13 CCDS53825.1 SSH1 gene_id:54434|Hs108|chr12 ( 703) 286 72.7 5.4e-13 CCDS9121.1 SSH1 gene_id:54434|Hs108|chr12 (1049) 286 72.8 7.7e-13 CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 283 72.1 8.1e-13 CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 275 70.1 8.9e-13 CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 ( 217) 271 69.2 1.9e-12 CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 268 68.6 4.1e-12 CCDS1234.1 DUSP12 gene_id:11266|Hs108|chr1 ( 340) 268 68.6 4.5e-12 CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 ( 394) 268 68.6 5.2e-12 CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 ( 314) 263 67.5 9.1e-12 CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 ( 176) 258 66.3 1.2e-11 CCDS11253.1 SSH2 gene_id:85464|Hs108|chr17 (1423) 267 68.6 1.9e-11 CCDS74024.1 SSH2 gene_id:85464|Hs108|chr17 (1450) 267 68.6 2e-11 CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 ( 367) 257 66.2 2.7e-11 CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 253 65.2 2.8e-11 CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 ( 188) 249 64.3 5e-11 >>CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 (184 aa) initn: 1250 init1: 1250 opt: 1250 Z-score: 1520.6 bits: 288.0 E(32554): 2.2e-78 Smith-Waterman score: 1250; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF 130 140 150 160 170 180 pF1KB6 LRRL :::: CCDS44 LRRL >>CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 (205 aa) initn: 1146 init1: 1146 opt: 1146 Z-score: 1394.2 bits: 264.8 E(32554): 2.4e-71 Smith-Waterman score: 1146; 100.0% identity (100.0% similar) in 169 aa overlap (1-169:1-169) 10 20 30 40 50 60 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS69 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS69 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS69 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILGKYKEQGRTEP 130 140 150 160 170 180 pF1KB6 LRRL CCDS69 QPGARRWSSFPALAPLTYDNYTTET 190 200 >>CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 (235 aa) initn: 706 init1: 686 opt: 686 Z-score: 837.7 bits: 162.0 E(32554): 2.4e-40 Smith-Waterman score: 686; 55.0% identity (82.2% similar) in 169 aa overlap (1-169:1-169) 10 20 30 40 50 60 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS :::::.:.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.: CCDS13 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA . .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....: CCDS13 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF : :::: ::..::.:: .. :. :.:..::::..: :: . .: CCDS13 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA 130 140 150 160 170 180 pF1KB6 LRRL CCDS13 TSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK 190 200 210 220 230 >>CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 (232 aa) initn: 659 init1: 639 opt: 643 Z-score: 785.8 bits: 152.4 E(32554): 1.9e-37 Smith-Waterman score: 643; 53.7% identity (81.5% similar) in 162 aa overlap (8-169:5-166) 10 20 30 40 50 60 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS .:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.: CCDS82 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA . .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....: CCDS82 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF : :::: ::..::.:: .. :. :.:..::::..: :: . .: CCDS82 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA 120 130 140 150 160 170 pF1KB6 LRRL CCDS82 TSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK 180 190 200 210 220 230 >>CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 (295 aa) initn: 572 init1: 572 opt: 572 Z-score: 698.4 bits: 136.5 E(32554): 1.4e-32 Smith-Waterman score: 572; 58.0% identity (84.7% similar) in 131 aa overlap (8-138:5-135) 10 20 30 40 50 60 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS .:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.: CCDS82 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA . .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....: CCDS82 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAF : :::: ::..::.:: CCDS82 TRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAAL 120 130 140 150 160 170 >>CCDS9033.1 DUSP6 gene_id:1848|Hs108|chr12 (381 aa) initn: 320 init1: 267 opt: 320 Z-score: 392.2 bits: 80.2 E(32554): 1.6e-15 Smith-Waterman score: 320; 41.0% identity (67.6% similar) in 139 aa overlap (7-140:209-345) 10 20 30 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILS .::: ::.: ::. . . : . . .::. CCDS90 DIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILN 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB6 VHDSARPMLEGV---KYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESC--LVHCLAG : . ..:.. :: :: .: ::::.. : :.:.:: : ::..: ::::::: CCDS90 VTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEA--RGKNCGVLVHCLAG 240 250 260 270 280 290 100 110 120 130 140 150 pF1KB6 VSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLK .:::::...::.: ... .:: :. .: .:: .:. :: .::. CCDS90 ISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNR 300 310 320 330 340 350 160 170 180 pF1KB6 EEYGESPLQDAEEAKNILAAPGILKFWAFLRRL CCDS90 VPAQQLYFTTPSNQNVYQVDSLQST 360 370 380 >>CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX (384 aa) initn: 321 init1: 251 opt: 320 Z-score: 392.1 bits: 80.2 E(32554): 1.6e-15 Smith-Waterman score: 320; 39.6% identity (66.4% similar) in 149 aa overlap (7-148:206-354) 10 20 30 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILS .:::.::.:. .:. . :.:.: . .::. CCDS14 SEADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILN 180 190 200 210 220 230 40 50 60 70 80 90 pF1KB6 VHDSARPMLE---GVKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVS : . ..: .: :: .: ::::.: : :.:.:: : .. . ::::::::: CCDS14 VTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVS 240 250 260 270 280 290 100 110 120 130 140 pF1KB6 RSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEK----HEVHQYRQW ::::...::.: .. .:: :. .: .:: .:. :: .::. .: :. .: CCDS14 RSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQG 300 310 320 330 340 350 150 160 170 180 pF1KB6 LKEEYGESPLQDAEEAKNILAAPGILKFWAFLRRL CCDS14 SGGQASAASNPPSFFTTPTSDGAFELAPT 360 370 380 >>CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 (482 aa) initn: 321 init1: 255 opt: 321 Z-score: 391.7 bits: 80.5 E(32554): 1.7e-15 Smith-Waterman score: 321; 38.8% identity (71.9% similar) in 139 aa overlap (5-140:322-460) 10 20 30 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHI .. ::: :..:: .::.: . ... .. .. CCDS15 ECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYV 300 310 320 330 340 350 40 50 60 70 80 90 pF1KB6 LSV--HDSARPMLEGV-KYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAG ..: : . .:. .: .::.:: .::: ..:.:...::.: . :.. :.:: :: CCDS15 INVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAG 360 370 380 390 400 410 100 110 120 130 140 150 pF1KB6 VSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLK ::::.:.::::.: : . :: . :.. : .::..:. :: :::. CCDS15 VSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRIL 420 430 440 450 460 470 160 170 180 pF1KB6 EEYGESPLQDAEEAKNILAAPGILKFWAFLRRL CCDS15 TPKLMGVETVV 480 >>CCDS33766.2 DUSP7 gene_id:1849|Hs108|chr3 (419 aa) initn: 317 init1: 255 opt: 312 Z-score: 381.9 bits: 78.5 E(32554): 6e-15 Smith-Waterman score: 312; 40.1% identity (65.0% similar) in 137 aa overlap (7-140:247-383) 10 20 30 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILS .::: ::.: ::. . . :.: . .::. CCDS33 SDGESDRELPSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILN 220 230 240 250 260 270 40 50 60 70 80 90 pF1KB6 VHDSARPMLEG---VKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVS : . .: : :: .: ::::.. : :.:.:: : : . . :::::::.: CCDS33 VTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGIS 280 290 300 310 320 330 100 110 120 130 140 150 pF1KB6 RSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEE ::::...::.: ... .:: :. .: .:: .:. :: .::. CCDS33 RSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHAS 340 350 360 370 380 390 160 170 180 pF1KB6 YGESPLQDAEEAKNILAAPGILKFWAFLRRL CCDS33 SEQLYFSTPTNHNLFPLNTLEST 400 410 >>CCDS9711.1 STYX gene_id:6815|Hs108|chr14 (223 aa) initn: 279 init1: 239 opt: 307 Z-score: 380.3 bits: 77.3 E(32554): 7.3e-15 Smith-Waterman score: 307; 37.8% identity (67.1% similar) in 143 aa overlap (5-139:29-171) 10 20 30 pF1KB6 MGNGMNKILPGLYIGNFKDARDAEQ--LSKNKVTHI :..:::::..: ...: .. :.:. .::: CCDS97 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 10 20 30 40 50 60 40 50 60 70 80 pF1KB6 LSVHDSA-----RPMLEGV-KYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHC . .... .: .. . .:: . ::.: .:. : : . .:: : . ::: CCDS97 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB6 LAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQ ::.:::...:::::: . . ..::. :. : : :::.:: .::::.: CCDS97 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 130 140 150 160 170 180 150 160 170 180 pF1KB6 WLKEEYGESPLQDAEEAKNILAAPGILKFWAFLRRL CCDS97 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 190 200 210 220 184 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:06:44 2016 done: Fri Nov 4 15:06:45 2016 Total Scan time: 1.870 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]