FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6804, 184 aa
1>>>pF1KB6804 184 - 184 aa - 184 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1718+/-0.000978; mu= 13.6689+/- 0.059
mean_var=73.2393+/-14.730, 0's: 0 Z-trim(106.4): 193 B-trim: 609 in 2/49
Lambda= 0.149866
statistics sampled from 8767 (8985) to 8767 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.276), width: 16
Scan time: 1.910
The best scores are: opt bits E(32554)
CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 ( 184) 1209 270.3 4.6e-73
CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 ( 184) 1128 252.8 8.5e-68
CCDS58253.1 RAP1B gene_id:5908|Hs108|chr12 ( 165) 750 171.1 3.1e-43
CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 ( 183) 750 171.1 3.4e-43
CCDS58254.1 RAP1B gene_id:5908|Hs108|chr12 ( 142) 744 169.7 6.9e-43
CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX ( 183) 744 169.8 8.4e-43
CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 ( 183) 737 168.3 2.4e-42
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 677 155.3 2e-38
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 670 153.8 5.6e-38
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 653 150.1 7.2e-37
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 633 145.8 1.4e-35
CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11 ( 204) 607 140.2 7.5e-34
CCDS3100.1 MRAS gene_id:22808|Hs108|chr3 ( 208) 606 140.0 8.9e-34
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 599 138.4 2.2e-33
CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 595 137.6 4.6e-33
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 581 134.6 3.9e-32
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 581 134.6 4.1e-32
CCDS11921.1 RIT2 gene_id:6014|Hs108|chr18 ( 217) 567 131.6 3.2e-31
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 561 130.3 7.5e-31
CCDS12774.1 RRAS gene_id:6237|Hs108|chr19 ( 218) 551 128.1 3.5e-30
CCDS6687.1 DIRAS2 gene_id:54769|Hs108|chr9 ( 199) 523 122.1 2.2e-28
CCDS12092.1 DIRAS1 gene_id:148252|Hs108|chr19 ( 198) 497 116.4 1.1e-26
CCDS53603.1 RRAS2 gene_id:22800|Hs108|chr11 ( 169) 487 114.2 4.2e-26
CCDS58036.1 RIT1 gene_id:6016|Hs108|chr1 ( 183) 484 113.6 7e-26
CCDS8673.1 RERG gene_id:85004|Hs108|chr12 ( 199) 467 109.9 9.5e-25
CCDS58252.1 RAP1B gene_id:5908|Hs108|chr12 ( 137) 463 109.0 1.3e-24
CCDS62431.1 RIT2 gene_id:6014|Hs108|chr18 ( 153) 446 105.3 1.8e-23
CCDS5927.1 RHEB gene_id:6009|Hs108|chr7 ( 184) 426 101.1 4.2e-22
CCDS76024.1 RAP2C gene_id:57826|Hs108|chrX ( 117) 406 96.6 5.9e-21
CCDS35246.1 ERAS gene_id:3266|Hs108|chrX ( 233) 396 94.6 4.5e-20
CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 ( 183) 387 92.6 1.4e-19
CCDS42410.1 RAB12 gene_id:201475|Hs108|chr18 ( 244) 375 90.1 1.1e-18
CCDS641.1 DIRAS3 gene_id:9077|Hs108|chr1 ( 229) 367 88.4 3.4e-18
CCDS1720.1 RAB10 gene_id:10890|Hs108|chr2 ( 200) 363 87.5 5.6e-18
CCDS1058.1 RAB13 gene_id:5872|Hs108|chr1 ( 203) 363 87.5 5.7e-18
CCDS10183.1 RAB8B gene_id:51762|Hs108|chr15 ( 207) 363 87.5 5.8e-18
CCDS3976.1 RAB3C gene_id:115827|Hs108|chr5 ( 227) 359 86.6 1.1e-17
CCDS12339.1 RAB8A gene_id:4218|Hs108|chr19 ( 207) 353 85.3 2.6e-17
CCDS53753.1 RERG gene_id:85004|Hs108|chr12 ( 180) 346 83.8 6.6e-17
CCDS9570.1 RAB2B gene_id:84932|Hs108|chr14 ( 216) 346 83.8 7.6e-17
CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 345 83.6 8.9e-17
CCDS560.1 RAB3B gene_id:5865|Hs108|chr1 ( 219) 345 83.6 9e-17
CCDS12372.1 RAB3A gene_id:5864|Hs108|chr19 ( 220) 345 83.6 9e-17
CCDS44544.1 RRAS2 gene_id:22800|Hs108|chr11 ( 127) 339 82.1 1.4e-16
CCDS12257.1 RAB3D gene_id:9545|Hs108|chr19 ( 219) 340 82.5 1.9e-16
CCDS4962.1 RAB23 gene_id:51715|Hs108|chr6 ( 237) 339 82.3 2.3e-16
CCDS46306.1 RAB1A gene_id:5861|Hs108|chr2 ( 205) 338 82.1 2.4e-16
CCDS6175.1 RAB2A gene_id:5862|Hs108|chr8 ( 212) 338 82.1 2.5e-16
CCDS82198.1 RAB37 gene_id:326624|Hs108|chr17 ( 196) 333 81.0 5e-16
CCDS3052.1 RAB7A gene_id:7879|Hs108|chr3 ( 207) 333 81.0 5.2e-16
>>CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 (184 aa)
initn: 1209 init1: 1209 opt: 1209 Z-score: 1425.3 bits: 270.3 E(32554): 4.6e-73
Smith-Waterman score: 1209; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS84 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
130 140 150 160 170 180
pF1KB6 CLLL
::::
CCDS84 CLLL
>>CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 (184 aa)
initn: 1128 init1: 1128 opt: 1128 Z-score: 1330.6 bits: 252.8 E(32554): 8.5e-68
Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
CCDS89 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
CCDS89 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
:::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.:
CCDS89 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
130 140 150 160 170 180
pF1KB6 CLLL
: ::
CCDS89 CQLL
>>CCDS58253.1 RAP1B gene_id:5908|Hs108|chr12 (165 aa)
initn: 1000 init1: 744 opt: 750 Z-score: 889.6 bits: 171.1 E(32554): 3.1e-43
Smith-Waterman score: 964; 85.3% identity (86.4% similar) in 184 aa overlap (1-184:1-165)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
::::::::::::::::::::::::::::::::::::::::::
CCDS58 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRK------------------
10 20 30 40
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
:::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
CCDS58 -EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
:::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.:
CCDS58 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
110 120 130 140 150 160
pF1KB6 CLLL
: ::
CCDS58 CQLL
>>CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 (183 aa)
initn: 699 init1: 636 opt: 750 Z-score: 889.0 bits: 171.1 E(32554): 3.4e-43
Smith-Waterman score: 750; 62.4% identity (84.0% similar) in 181 aa overlap (1-181:1-180)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..::: . .::::::::
CCDS94 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: : ::.:::::: ::
CCDS94 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
:.:: :.. .:. ::..: .: :.:.::::: :.:.: ..:::.: . .: : ..
CCDS94 ESEREVSSSEGRALAEEW-GCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSA
130 140 150 160 170
pF1KB6 CLLL
:
CCDS94 CNIQ
180
>>CCDS58254.1 RAP1B gene_id:5908|Hs108|chr12 (142 aa)
initn: 847 init1: 744 opt: 744 Z-score: 883.5 bits: 169.7 E(32554): 6.9e-43
Smith-Waterman score: 767; 72.8% identity (73.9% similar) in 184 aa overlap (1-184:1-142)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
:::::::::::::::::::
CCDS58 MREYKLVVLGSGGVGKSAL-----------------------------------------
10
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
:::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
CCDS58 -EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
:::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.:
CCDS58 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
80 90 100 110 120 130
pF1KB6 CLLL
: ::
CCDS58 CQLL
140
>>CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX (183 aa)
initn: 703 init1: 634 opt: 744 Z-score: 881.9 bits: 169.8 E(32554): 8.4e-43
Smith-Waterman score: 744; 61.7% identity (83.1% similar) in 183 aa overlap (1-183:1-182)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..::: . .::::::::
CCDS14 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: : ::.:::::: ::
CCDS14 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
: :: : . .:. ::..: .: :.:.::::: :.:.: ..:::.: .. ::. .
CCDS14 EPEREVMSSEGRALAQEW-GCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTT
130 140 150 160 170
pF1KB6 CLLL
:..
CCDS14 CVVQ
180
>>CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 (183 aa)
initn: 697 init1: 635 opt: 737 Z-score: 873.8 bits: 168.3 E(32554): 2.4e-42
Smith-Waterman score: 737; 60.9% identity (83.2% similar) in 184 aa overlap (1-184:1-183)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..::: . .::::::::
CCDS31 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: : ::::::::: ::
CCDS31 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
: :: :. .:. ::..: .: :.:.:::.: .:.:.: ..:::.: . . . ..
CCDS31 EGEREVSYGEGKALAEEW-SCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSA
130 140 150 160 170
pF1KB6 CLLL
:..:
CCDS31 CVIL
180
>>CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 (188 aa)
initn: 642 init1: 557 opt: 677 Z-score: 803.5 bits: 155.3 E(32554): 2e-38
Smith-Waterman score: 677; 55.3% identity (81.1% similar) in 190 aa overlap (1-184:1-188)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
: ::::::.:.:::::::::.:..:. ::..::::::::::::: .: . :.:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
:...:::: ::..:.:: :..:. ..:.:.. :::: ::::.:::::.::::::::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINR---KTPVEKKKPK
. :.: .:.:.:::.. . :.:.:::.. .:.. :: :::.: . : . :: :
CCDS87 PS-RTVDTKQAQDLARSY-GIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKK
130 140 150 160 170
180
pF1KB6 KKS---CLLL
::: :...
CCDS87 KKSKTKCVIM
180
>>CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 (189 aa)
initn: 597 init1: 549 opt: 670 Z-score: 795.3 bits: 153.8 E(32554): 5.6e-38
Smith-Waterman score: 670; 54.5% identity (80.1% similar) in 191 aa overlap (1-184:1-189)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
: ::::::.:.:::::::::.:..:. ::..::::::::::::: .: . :.:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
:...:::: ::..:.:: :..:. ..:.:.. :::: ::::.:::::.::::::::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQIN----RKTPVEKKKP
. :.: .:.:.:::.. . :.:.:::.. :.. :: :::.: .: :.: :
CCDS87 PS-RTVDTKQAQDLARSY-GIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTP
130 140 150 160 170
180
pF1KB6 ---KKKSCLLL
: :.:...
CCDS87 GCVKIKKCIIM
180
>>CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 (189 aa)
initn: 595 init1: 546 opt: 653 Z-score: 775.4 bits: 150.1 E(32554): 7.2e-37
Smith-Waterman score: 653; 55.0% identity (83.9% similar) in 180 aa overlap (1-180:1-177)
10 20 30 40 50 60
pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
: ::::::.:.:::::::::.:..:. ::..::::::::::::: .: . :.:.::::::
CCDS76 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
:...:::: ::..:.:: :..:. ..:.:... :::: ::::..::::.::::::::
CCDS76 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
:.: ..:.:.:::.. . ..:.:::.. .:.. :: :::.: :. ..: .: .:
CCDS76 A-ARTVESRQAQDLARSY-GIPYIETSAKTRQGVEDAFYTLVREI-RQHKLRKLNPPDES
130 140 150 160 170
pF1KB6 CLLL
CCDS76 GPGCMSCKCVLS
180
184 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:09:52 2016 done: Sat Nov 5 00:09:53 2016
Total Scan time: 1.910 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]