FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6804, 184 aa 1>>>pF1KB6804 184 - 184 aa - 184 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3478+/-0.000418; mu= 12.8207+/- 0.026 mean_var=77.6839+/-15.415, 0's: 0 Z-trim(113.2): 431 B-trim: 652 in 1/54 Lambda= 0.145515 statistics sampled from 21967 (22470) to 21967 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.263), width: 16 Scan time: 5.580 The best scores are: opt bits E(85289) XP_016857452 (OMIM: 179520) PREDICTED: ras-related ( 184) 1209 263.1 1.9e-70 XP_016857453 (OMIM: 179520) PREDICTED: ras-related ( 184) 1209 263.1 1.9e-70 XP_016857451 (OMIM: 179520) PREDICTED: ras-related ( 184) 1209 263.1 1.9e-70 NP_002875 (OMIM: 179520) ras-related protein Rap-1 ( 184) 1209 263.1 1.9e-70 NP_001010935 (OMIM: 179520) ras-related protein Ra ( 184) 1209 263.1 1.9e-70 NP_001278825 (OMIM: 179520) ras-related protein Ra ( 184) 1209 263.1 1.9e-70 NP_056461 (OMIM: 179530) ras-related protein Rap-1 ( 184) 1128 246.1 2.4e-65 NP_001010942 (OMIM: 179530) ras-related protein Ra ( 184) 1128 246.1 2.4e-65 XP_016857449 (OMIM: 179520) PREDICTED: ras-related ( 195) 1038 227.2 1.2e-59 XP_016857450 (OMIM: 179520) PREDICTED: ras-related ( 195) 1038 227.2 1.2e-59 NP_001238850 (OMIM: 179530) ras-related protein Ra ( 165) 750 166.7 1.7e-41 NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 750 166.7 1.9e-41 NP_001238847 (OMIM: 179530) ras-related protein Ra ( 142) 744 165.4 3.7e-41 NP_001238846 (OMIM: 179530) ras-related protein Ra ( 142) 744 165.4 3.7e-41 NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 737 164.0 1.2e-40 NP_004976 (OMIM: 109800,114480,137215,163200,19007 ( 188) 677 151.4 7.9e-37 XP_011518955 (OMIM: 109800,114480,137215,163200,19 ( 188) 677 151.4 7.9e-37 NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 670 149.9 2.2e-36 XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 670 149.9 2.2e-36 XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 670 150.0 2.5e-36 NP_005334 (OMIM: 109800,137550,162900,163200,18847 ( 189) 653 146.4 2.6e-35 NP_001123914 (OMIM: 109800,137550,162900,163200,18 ( 189) 653 146.4 2.6e-35 NP_002515 (OMIM: 114500,137550,162900,163200,16479 ( 189) 633 142.2 4.8e-34 NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 607 136.7 2.2e-32 NP_036351 (OMIM: 608435) ras-related protein M-Ras ( 208) 606 136.5 2.6e-32 XP_005247285 (OMIM: 608435) PREDICTED: ras-related ( 208) 606 136.5 2.6e-32 NP_001078518 (OMIM: 608435) ras-related protein M- ( 208) 606 136.5 2.6e-32 NP_001239019 (OMIM: 608435) ras-related protein M- ( 208) 606 136.5 2.6e-32 XP_016861376 (OMIM: 608435) PREDICTED: ras-related ( 208) 606 136.5 2.6e-32 NP_789765 (OMIM: 109800,137550,162900,163200,18847 ( 170) 599 135.0 6.2e-32 NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 595 134.2 1.3e-31 XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 595 134.2 1.3e-31 XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 595 134.2 1.3e-31 NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 581 131.3 1e-30 NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 581 131.3 1.1e-30 NP_002921 (OMIM: 609592) GTP-binding protein Rit2 ( 217) 567 128.3 7.9e-30 NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 561 127.1 1.8e-29 XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 561 127.1 1.8e-29 XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 561 127.1 1.8e-29 XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 561 127.1 1.8e-29 XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 561 127.1 1.8e-29 XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 561 127.1 2e-29 XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 561 127.1 2e-29 XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 561 127.1 2e-29 NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 551 125.0 8.1e-29 NP_060064 (OMIM: 607863) GTP-binding protein Di-Ra ( 199) 523 119.1 4.4e-27 XP_005247286 (OMIM: 608435) PREDICTED: ras-related ( 170) 511 116.5 2.3e-26 NP_660156 (OMIM: 607862) GTP-binding protein Di-Ra ( 198) 497 113.6 1.9e-25 XP_011526015 (OMIM: 607862) PREDICTED: GTP-binding ( 232) 497 113.7 2.2e-25 XP_016872852 (OMIM: 600098) PREDICTED: ras-related ( 182) 493 112.8 3.3e-25 >>XP_016857452 (OMIM: 179520) PREDICTED: ras-related pro (184 aa) initn: 1209 init1: 1209 opt: 1209 Z-score: 1385.9 bits: 263.1 E(85289): 1.9e-70 Smith-Waterman score: 1209; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB6 CLLL :::: XP_016 CLLL >>XP_016857453 (OMIM: 179520) PREDICTED: ras-related pro (184 aa) initn: 1209 init1: 1209 opt: 1209 Z-score: 1385.9 bits: 263.1 E(85289): 1.9e-70 Smith-Waterman score: 1209; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB6 CLLL :::: XP_016 CLLL >>XP_016857451 (OMIM: 179520) PREDICTED: ras-related pro (184 aa) initn: 1209 init1: 1209 opt: 1209 Z-score: 1385.9 bits: 263.1 E(85289): 1.9e-70 Smith-Waterman score: 1209; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB6 CLLL :::: XP_016 CLLL >>NP_002875 (OMIM: 179520) ras-related protein Rap-1A pr (184 aa) initn: 1209 init1: 1209 opt: 1209 Z-score: 1385.9 bits: 263.1 E(85289): 1.9e-70 Smith-Waterman score: 1209; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB6 CLLL :::: NP_002 CLLL >>NP_001010935 (OMIM: 179520) ras-related protein Rap-1A (184 aa) initn: 1209 init1: 1209 opt: 1209 Z-score: 1385.9 bits: 263.1 E(85289): 1.9e-70 Smith-Waterman score: 1209; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB6 CLLL :::: NP_001 CLLL >>NP_001278825 (OMIM: 179520) ras-related protein Rap-1A (184 aa) initn: 1209 init1: 1209 opt: 1209 Z-score: 1385.9 bits: 263.1 E(85289): 1.9e-70 Smith-Waterman score: 1209; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB6 CLLL :::: NP_001 CLLL >>NP_056461 (OMIM: 179530) ras-related protein Rap-1b is (184 aa) initn: 1128 init1: 1128 opt: 1128 Z-score: 1294.0 bits: 246.1 E(85289): 2.4e-65 Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_056 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_056 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS :::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.: NP_056 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS 130 140 150 160 170 180 pF1KB6 CLLL : :: NP_056 CQLL >>NP_001010942 (OMIM: 179530) ras-related protein Rap-1b (184 aa) initn: 1128 init1: 1128 opt: 1128 Z-score: 1294.0 bits: 246.1 E(85289): 2.4e-65 Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS :::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.: NP_001 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS 130 140 150 160 170 180 pF1KB6 CLLL : :: NP_001 CQLL >>XP_016857449 (OMIM: 179520) PREDICTED: ras-related pro (195 aa) initn: 1057 init1: 1038 opt: 1038 Z-score: 1191.6 bits: 227.2 E(85289): 1.2e-59 Smith-Waterman score: 1038; 98.1% identity (99.4% similar) in 160 aa overlap (1-160:1-160) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS ::::::::::::::::::::::::::::::::::::. :. XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEVTYNCWAAQTSAFLVCFKLTARLL 130 140 150 160 170 180 pF1KB6 CLLL XP_016 RKNFYLLSNLDSIIL 190 >>XP_016857450 (OMIM: 179520) PREDICTED: ras-related pro (195 aa) initn: 1057 init1: 1038 opt: 1038 Z-score: 1191.6 bits: 227.2 E(85289): 1.2e-59 Smith-Waterman score: 1038; 98.1% identity (99.4% similar) in 160 aa overlap (1-160:1-160) 10 20 30 40 50 60 pF1KB6 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS ::::::::::::::::::::::::::::::::::::. :. XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEVTYNCWAAQTSAFLVCFKLTARLL 130 140 150 160 170 180 pF1KB6 CLLL XP_016 RKNFYLLSNLDSIIL 190 184 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:09:53 2016 done: Sat Nov 5 00:09:54 2016 Total Scan time: 5.580 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]