FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6809, 159 aa 1>>>pF1KB6809 159 - 159 aa - 159 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5684+/-0.00035; mu= 15.5898+/- 0.022 mean_var=50.5056+/-10.293, 0's: 0 Z-trim(113.4): 22 B-trim: 0 in 0/51 Lambda= 0.180470 statistics sampled from 22732 (22743) to 22732 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.267), width: 16 Scan time: 5.260 The best scores are: opt bits E(85289) NP_065083 (OMIM: 608729) type-1 angiotensin II rec ( 159) 1066 284.8 3.9e-77 XP_011540102 (OMIM: 608729) PREDICTED: type-1 angi ( 171) 1013 271.0 5.9e-73 NP_001035284 (OMIM: 608729) type-1 angiotensin II ( 152) 998 267.1 8.1e-72 XP_011540101 (OMIM: 608729) PREDICTED: type-1 angi ( 164) 945 253.3 1.2e-67 NP_001035287 (OMIM: 608729) type-1 angiotensin II ( 147) 130 41.1 0.00084 NP_001035286 (OMIM: 608729) type-1 angiotensin II ( 155) 130 41.1 0.00088 >>NP_065083 (OMIM: 608729) type-1 angiotensin II recepto (159 aa) initn: 1066 init1: 1066 opt: 1066 Z-score: 1505.8 bits: 284.8 E(85289): 3.9e-77 Smith-Waterman score: 1066; 100.0% identity (100.0% similar) in 159 aa overlap (1-159:1-159) 10 20 30 40 50 60 pF1KB6 MELPAVNLKVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MELPAVNLKVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFLGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGGELLVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGGELLVH 70 80 90 100 110 120 130 140 150 pF1KB6 TGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY ::::::::::::::::::::::::::::::::::::::: NP_065 TGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY 130 140 150 >>XP_011540102 (OMIM: 608729) PREDICTED: type-1 angioten (171 aa) initn: 1052 init1: 1010 opt: 1013 Z-score: 1430.7 bits: 271.0 E(85289): 5.9e-73 Smith-Waterman score: 1032; 93.0% identity (93.0% similar) in 171 aa overlap (1-159:1-171) 10 20 30 40 pF1KB6 MELPAVNLK------------VILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQR ::::::::: ::::::::::::::::::::::::::::::::::::::: XP_011 MELPAVNLKCASSSVPRNHPHVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 DSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYH 70 80 90 100 110 120 110 120 130 140 150 pF1KB6 MYRERGGELLVHTGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYRERGGELLVHTGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY 130 140 150 160 170 >>NP_001035284 (OMIM: 608729) type-1 angiotensin II rece (152 aa) initn: 777 init1: 777 opt: 998 Z-score: 1410.4 bits: 267.1 E(85289): 8.1e-72 Smith-Waterman score: 998; 95.6% identity (95.6% similar) in 159 aa overlap (1-159:1-152) 10 20 30 40 50 60 pF1KB6 MELPAVNLKVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELPAVNLKVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFLGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGGELLVH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYHMYRERGG----- 70 80 90 100 110 130 140 150 pF1KB6 TGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY ::::::::::::::::::::::::::::::::::::: NP_001 --FLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY 120 130 140 150 >>XP_011540101 (OMIM: 608729) PREDICTED: type-1 angioten (164 aa) initn: 763 init1: 721 opt: 945 Z-score: 1335.3 bits: 253.3 E(85289): 1.2e-67 Smith-Waterman score: 964; 88.9% identity (88.9% similar) in 171 aa overlap (1-159:1-164) 10 20 30 40 pF1KB6 MELPAVNLK------------VILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQR ::::::::: ::::::::::::::::::::::::::::::::::::::: XP_011 MELPAVNLKCASSSVPRNHPHVILLGHWLLTTWGCIVFSGSYAWANFTILALGVWAVAQR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 DSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSIDAISMFLGGLLATIFLDIVHISIFYPRVSLTDTGRFGVGMAILSLLLKPLSCCFVYH 70 80 90 100 110 120 110 120 130 140 150 pF1KB6 MYRERGGELLVHTGFLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY ::::::: ::::::::::::::::::::::::::::::::::::: XP_011 MYRERGG-------FLGSSQDRSAYQTIDSAEAPADPFAVPEGRSQDARGY 130 140 150 160 >>NP_001035287 (OMIM: 608729) type-1 angiotensin II rece (147 aa) initn: 142 init1: 129 opt: 130 Z-score: 189.2 bits: 41.1 E(85289): 0.00084 Smith-Waterman score: 130; 91.3% identity (91.3% similar) in 23 aa overlap (1-21:1-23) 10 20 30 40 50 pF1KB6 MELPAVNLKVILLGHWLLTT--WGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFL :::::::::::::::::::: : NP_001 MELPAVNLKVILLGHWLLTTCFWRHFSAKPRLETIELTCALCKLRSAAHRATAGLHCILR 10 20 30 40 50 60 >>NP_001035286 (OMIM: 608729) type-1 angiotensin II rece (155 aa) initn: 142 init1: 129 opt: 130 Z-score: 188.9 bits: 41.1 E(85289): 0.00088 Smith-Waterman score: 130; 91.3% identity (91.3% similar) in 23 aa overlap (1-21:1-23) 10 20 30 40 50 pF1KB6 MELPAVNLKVILLGHWLLTT--WGCIVFSGSYAWANFTILALGVWAVAQRDSIDAISMFL :::::::::::::::::::: : NP_001 MELPAVNLKVILLGHWLLTTCFWRHFSAKPRLETIELTCALCKLRSAAHRATAGLHCILR 10 20 30 40 50 60 159 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:38:37 2016 done: Fri Nov 4 14:38:38 2016 Total Scan time: 5.260 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]