FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6810, 185 aa
1>>>pF1KB6810 185 - 185 aa - 185 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4726+/-0.000293; mu= 8.4197+/- 0.018
mean_var=106.3971+/-20.912, 0's: 0 Z-trim(120.0): 43 B-trim: 670 in 2/54
Lambda= 0.124340
statistics sampled from 34566 (34610) to 34566 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.406), width: 16
Scan time: 6.210
The best scores are: opt bits E(85289)
NP_001120700 (OMIM: 604511) chromobox protein homo ( 185) 1238 231.7 5.2e-61
NP_006798 (OMIM: 604511) chromobox protein homolog ( 185) 1238 231.7 5.2e-61
NP_057671 (OMIM: 604477) chromobox protein homolog ( 183) 848 161.7 5.9e-40
XP_005249668 (OMIM: 604477) PREDICTED: chromobox p ( 183) 848 161.7 5.9e-40
NP_009207 (OMIM: 604477) chromobox protein homolog ( 183) 848 161.7 5.9e-40
NP_036249 (OMIM: 604478) chromobox protein homolog ( 191) 781 149.7 2.5e-36
NP_001120793 (OMIM: 604478) chromobox protein homo ( 191) 781 149.7 2.5e-36
NP_001120794 (OMIM: 604478) chromobox protein homo ( 191) 781 149.7 2.5e-36
NP_116036 (OMIM: 602770,613080) chromobox protein ( 211) 205 46.4 3.5e-05
NP_005180 (OMIM: 602770,613080) chromobox protein ( 532) 208 47.2 5.1e-05
XP_011523684 (OMIM: 602770,613080) PREDICTED: chro ( 586) 208 47.3 5.5e-05
NP_059990 (OMIM: 611626) M-phase phosphoprotein 8 ( 860) 207 47.2 8.5e-05
XP_011533426 (OMIM: 611626) PREDICTED: M-phase pho ( 879) 207 47.2 8.6e-05
XP_011513299 (OMIM: 603778) PREDICTED: chromodomai ( 522) 202 46.2 0.00011
NP_004815 (OMIM: 603778) chromodomain Y-like prote ( 544) 202 46.2 0.00011
XP_006724240 (OMIM: 608457) PREDICTED: chromobox p ( 192) 195 44.6 0.00011
XP_006724239 (OMIM: 608457) PREDICTED: chromobox p ( 200) 191 43.9 0.00019
XP_005261470 (OMIM: 608457) PREDICTED: chromobox p ( 158) 185 42.8 0.00033
XP_016884168 (OMIM: 608457) PREDICTED: chromobox p ( 250) 185 42.9 0.00048
NP_783640 (OMIM: 608457) chromobox protein homolog ( 251) 185 42.9 0.00048
XP_011528327 (OMIM: 608457) PREDICTED: chromobox p ( 165) 181 42.1 0.00057
XP_006724241 (OMIM: 608457) PREDICTED: chromobox p ( 166) 181 42.1 0.00057
XP_006724238 (OMIM: 608457) PREDICTED: chromobox p ( 258) 181 42.2 0.00081
XP_006724237 (OMIM: 608457) PREDICTED: chromobox p ( 259) 181 42.2 0.00082
NP_003646 (OMIM: 603079) E3 SUMO-protein ligase CB ( 560) 185 43.1 0.00092
NP_001180355 (OMIM: 606503) histone-lysine N-methy ( 230) 176 41.3 0.0014
NP_001180353 (OMIM: 606503) histone-lysine N-methy ( 410) 176 41.4 0.0022
XP_011529814 (OMIM: 400016,415000) PREDICTED: test ( 470) 165 39.5 0.0096
>>NP_001120700 (OMIM: 604511) chromobox protein homolog (185 aa)
initn: 1238 init1: 1238 opt: 1238 Z-score: 1216.3 bits: 231.7 E(85289): 5.2e-61
Smith-Waterman score: 1238; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDK
130 140 150 160 170 180
pF1KB6 KDDKN
:::::
NP_001 KDDKN
>>NP_006798 (OMIM: 604511) chromobox protein homolog 1 [ (185 aa)
initn: 1238 init1: 1238 opt: 1238 Z-score: 1216.3 bits: 231.7 E(85289): 5.2e-61
Smith-Waterman score: 1238; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDK
130 140 150 160 170 180
pF1KB6 KDDKN
:::::
NP_006 KDDKN
>>NP_057671 (OMIM: 604477) chromobox protein homolog 3 [ (183 aa)
initn: 848 init1: 449 opt: 848 Z-score: 838.3 bits: 161.7 E(85289): 5.9e-40
Smith-Waterman score: 848; 73.6% identity (88.2% similar) in 178 aa overlap (1-178:11-181)
10 20 30 40 50
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDN
:::::: :. ..: : : ::.:::::::::::.:::::.::::::.: ::
NP_057 MASNKTTLQKMGKKQNGKS-KKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADN
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 TWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKP
:::::::::::.:: ::.:::...: : : :::. :::: ...:: :::.. ..::
NP_057 TWEPEENLDCPELIEAFLNSQKAGKEKD---GTKRKSLSDSE--SDDSKSKKKRDAADKP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW
:::::::.:::::::::::::::::::::.::::::: :::::.::::.::.::::::::
NP_057 RGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW
120 130 140 150 160 170
180
pF1KB6 HSYPSEDDDKKDDKN
:: : ::.
NP_057 HSCP-EDEAQ
180
>>XP_005249668 (OMIM: 604477) PREDICTED: chromobox prote (183 aa)
initn: 848 init1: 449 opt: 848 Z-score: 838.3 bits: 161.7 E(85289): 5.9e-40
Smith-Waterman score: 848; 73.6% identity (88.2% similar) in 178 aa overlap (1-178:11-181)
10 20 30 40 50
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDN
:::::: :. ..: : : ::.:::::::::::.:::::.::::::.: ::
XP_005 MASNKTTLQKMGKKQNGKS-KKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADN
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 TWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKP
:::::::::::.:: ::.:::...: : : :::. :::: ...:: :::.. ..::
XP_005 TWEPEENLDCPELIEAFLNSQKAGKEKD---GTKRKSLSDSE--SDDSKSKKKRDAADKP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW
:::::::.:::::::::::::::::::::.::::::: :::::.::::.::.::::::::
XP_005 RGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW
120 130 140 150 160 170
180
pF1KB6 HSYPSEDDDKKDDKN
:: : ::.
XP_005 HSCP-EDEAQ
180
>>NP_009207 (OMIM: 604477) chromobox protein homolog 3 [ (183 aa)
initn: 848 init1: 449 opt: 848 Z-score: 838.3 bits: 161.7 E(85289): 5.9e-40
Smith-Waterman score: 848; 73.6% identity (88.2% similar) in 178 aa overlap (1-178:11-181)
10 20 30 40 50
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDN
:::::: :. ..: : : ::.:::::::::::.:::::.::::::.: ::
NP_009 MASNKTTLQKMGKKQNGKS-KKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADN
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 TWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKP
:::::::::::.:: ::.:::...: : : :::. :::: ...:: :::.. ..::
NP_009 TWEPEENLDCPELIEAFLNSQKAGKEKD---GTKRKSLSDSE--SDDSKSKKKRDAADKP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTW
:::::::.:::::::::::::::::::::.::::::: :::::.::::.::.::::::::
NP_009 RGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTW
120 130 140 150 160 170
180
pF1KB6 HSYPSEDDDKKDDKN
:: : ::.
NP_009 HSCP-EDEAQ
180
>>NP_036249 (OMIM: 604478) chromobox protein homolog 5 [ (191 aa)
initn: 817 init1: 414 opt: 781 Z-score: 773.1 bits: 149.7 E(85289): 2.5e-36
Smith-Waterman score: 781; 63.9% identity (82.7% similar) in 191 aa overlap (1-183:1-187)
10 20 30 40 50 60
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
:::: .:. .. :.:::::::::::::::::.:::::::::::.: ::::::.::::
NP_036 MGKK-TKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDC
10 20 30 40 50
70 80 90 100 110
pF1KB6 PDLIAEFLQSQKTAHE------TDKSEGGKRKAD-SDSEDKGEESKPKKKKEESEK-PRG
:.::.::... : .: .:::..:::.. :.: : . : :::.:.:. ::
NP_036 PELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSAD---DIKSKKKREQSNDIARG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 FARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHS
: ::::::.::::::: :.::::::::..:::::: ::::::::::.::.:::::::::.
NP_036 FERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHA
120 130 140 150 160 170
180
pF1KB6 YPSEDDDKKDDKN
:: . ..:. .
NP_036 YPEDAENKEKETAKS
180 190
>>NP_001120793 (OMIM: 604478) chromobox protein homolog (191 aa)
initn: 817 init1: 414 opt: 781 Z-score: 773.1 bits: 149.7 E(85289): 2.5e-36
Smith-Waterman score: 781; 63.9% identity (82.7% similar) in 191 aa overlap (1-183:1-187)
10 20 30 40 50 60
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
:::: .:. .. :.:::::::::::::::::.:::::::::::.: ::::::.::::
NP_001 MGKK-TKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDC
10 20 30 40 50
70 80 90 100 110
pF1KB6 PDLIAEFLQSQKTAHE------TDKSEGGKRKAD-SDSEDKGEESKPKKKKEESEK-PRG
:.::.::... : .: .:::..:::.. :.: : . : :::.:.:. ::
NP_001 PELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSAD---DIKSKKKREQSNDIARG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 FARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHS
: ::::::.::::::: :.::::::::..:::::: ::::::::::.::.:::::::::.
NP_001 FERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHA
120 130 140 150 160 170
180
pF1KB6 YPSEDDDKKDDKN
:: . ..:. .
NP_001 YPEDAENKEKETAKS
180 190
>>NP_001120794 (OMIM: 604478) chromobox protein homolog (191 aa)
initn: 817 init1: 414 opt: 781 Z-score: 773.1 bits: 149.7 E(85289): 2.5e-36
Smith-Waterman score: 781; 63.9% identity (82.7% similar) in 191 aa overlap (1-183:1-187)
10 20 30 40 50 60
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
:::: .:. .. :.:::::::::::::::::.:::::::::::.: ::::::.::::
NP_001 MGKK-TKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDC
10 20 30 40 50
70 80 90 100 110
pF1KB6 PDLIAEFLQSQKTAHE------TDKSEGGKRKAD-SDSEDKGEESKPKKKKEESEK-PRG
:.::.::... : .: .:::..:::.. :.: : . : :::.:.:. ::
NP_001 PELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSAD---DIKSKKKREQSNDIARG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 FARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHS
: ::::::.::::::: :.::::::::..:::::: ::::::::::.::.:::::::::.
NP_001 FERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHA
120 130 140 150 160 170
180
pF1KB6 YPSEDDDKKDDKN
:: . ..:. .
NP_001 YPEDAENKEKETAKS
180 190
>>NP_116036 (OMIM: 602770,613080) chromobox protein homo (211 aa)
initn: 229 init1: 172 opt: 205 Z-score: 214.0 bits: 46.4 E(85289): 3.5e-05
Smith-Waterman score: 205; 33.3% identity (65.7% similar) in 105 aa overlap (10-114:1-104)
10 20 30 40 50 60
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
.::. :. ...: .:..:. :::.:::.::.:.:.. :.::::::.
NP_116 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPE
: :. : :... .:... . ::: . . : ...: . :.:
NP_116 PRLLLAF-QKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKVGGCAGYADPTSQH
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 RIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDK
NP_116 PLGVGGRQREGLGPSGRGWHFCQQSVPLLGKQEPPFFLSLSFCCQGPQPAESSSPPLPGA
120 130 140 150 160 170
>>NP_005180 (OMIM: 602770,613080) chromobox protein homo (532 aa)
initn: 199 init1: 199 opt: 208 Z-score: 211.1 bits: 47.2 E(85289): 5.1e-05
Smith-Waterman score: 208; 34.3% identity (67.6% similar) in 102 aa overlap (10-110:1-101)
10 20 30 40 50 60
pF1KB6 MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDC
.::. :. ...: .:..:. :::.:::.::.:.:.. :.::::::.
NP_005 MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILD
10 20 30 40 50
70 80 90 100 110
pF1KB6 PDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKK-EESEKPRGFARGLEP
: :. : :... .:... . ::: . . : ...: .: . :
NP_005 PRLLLAF-QKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDD
NP_005 SSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLP
120 130 140 150 160 170
185 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:09:30 2016 done: Sat Nov 5 20:09:30 2016
Total Scan time: 6.210 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]