FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6813, 160 aa 1>>>pF1KB6813 160 - 160 aa - 160 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4019+/-0.000646; mu= 11.9657+/- 0.039 mean_var=71.0484+/-13.696, 0's: 0 Z-trim(110.7): 23 B-trim: 68 in 1/54 Lambda= 0.152159 statistics sampled from 11823 (11835) to 11823 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.364), width: 16 Scan time: 1.630 The best scores are: opt bits E(32554) CCDS31836.1 PTGES3 gene_id:10728|Hs108|chr12 ( 160) 1146 259.9 5e-70 CCDS73485.1 PTGES3 gene_id:10728|Hs108|chr12 ( 164) 1139 258.3 1.5e-69 CCDS61160.1 PTGES3 gene_id:10728|Hs108|chr12 ( 139) 906 207.1 3.2e-54 CCDS61159.1 PTGES3 gene_id:10728|Hs108|chr12 ( 130) 687 159.0 9e-40 CCDS61158.1 PTGES3 gene_id:10728|Hs108|chr12 ( 127) 472 111.8 1.4e-25 CCDS45691.1 AARSD1 gene_id:100885850|Hs108|chr17 ( 586) 427 102.4 4.7e-22 CCDS11447.1 AARSD1 gene_id:100885850|Hs108|chr17 ( 525) 367 89.2 4e-18 CCDS45692.1 PTGES3L gene_id:100885848|Hs108|chr17 ( 161) 317 77.9 3e-15 >>CCDS31836.1 PTGES3 gene_id:10728|Hs108|chr12 (160 aa) initn: 1146 init1: 1146 opt: 1146 Z-score: 1370.8 bits: 259.9 E(32554): 5e-70 Smith-Waterman score: 1146; 100.0% identity (100.0% similar) in 160 aa overlap (1-160:1-160) 10 20 30 40 50 60 pF1KB6 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNF 70 80 90 100 110 120 130 140 150 160 pF1KB6 DRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE :::::::::::::::::::::::::::::::::::::::: CCDS31 DRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE 130 140 150 160 >>CCDS73485.1 PTGES3 gene_id:10728|Hs108|chr12 (164 aa) initn: 1139 init1: 1139 opt: 1139 Z-score: 1362.3 bits: 258.3 E(32554): 1.5e-69 Smith-Waterman score: 1139; 100.0% identity (100.0% similar) in 159 aa overlap (2-160:6-164) 10 20 30 40 50 pF1KB6 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MSLEKQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 HCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 HCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDED 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 MSNFDRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE :::::::::::::::::::::::::::::::::::::::::::: CCDS73 MSNFDRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE 130 140 150 160 >>CCDS61160.1 PTGES3 gene_id:10728|Hs108|chr12 (139 aa) initn: 901 init1: 901 opt: 906 Z-score: 1086.9 bits: 207.1 E(32554): 3.2e-54 Smith-Waterman score: 945; 86.9% identity (86.9% similar) in 160 aa overlap (1-160:1-139) 10 20 30 40 50 60 pF1KB6 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNF 70 80 90 100 110 120 130 140 150 160 pF1KB6 DRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE ::::: :::::::::::::: CCDS61 DRFSE---------------------DSQDSDDEKMPDLE 130 >>CCDS61159.1 PTGES3 gene_id:10728|Hs108|chr12 (130 aa) initn: 692 init1: 677 opt: 687 Z-score: 827.5 bits: 159.0 E(32554): 9e-40 Smith-Waterman score: 850; 81.2% identity (81.2% similar) in 160 aa overlap (1-160:1-130) 10 20 30 40 50 60 pF1KB6 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNF ::::::::::::::::::::::::::::::::::: CCDS61 PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAK------------------------- 70 80 90 130 140 150 160 pF1KB6 DRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE ::::::::::::::::::::::::::::::::::: CCDS61 -----MMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE 100 110 120 130 >>CCDS61158.1 PTGES3 gene_id:10728|Hs108|chr12 (127 aa) initn: 900 init1: 472 opt: 472 Z-score: 572.6 bits: 111.8 E(32554): 1.4e-25 Smith-Waterman score: 838; 79.4% identity (79.4% similar) in 160 aa overlap (1-160:1-127) 10 20 30 40 50 60 pF1KB6 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNF :: ::::::::::::::::::::::::: CCDS61 PN---------------------------------LNWLSVDFNNWKDWEDDSDEDMSNF 70 80 130 140 150 160 pF1KB6 DRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE :::::::::::::::::::::::::::::::::::::::: CCDS61 DRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE 90 100 110 120 >>CCDS45691.1 AARSD1 gene_id:100885850|Hs108|chr17 (586 aa) initn: 444 init1: 272 opt: 427 Z-score: 509.4 bits: 102.4 E(32554): 4.7e-22 Smith-Waterman score: 427; 42.4% identity (71.5% similar) in 144 aa overlap (2-145:47-187) 10 20 30 pF1KB6 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNF : : . :::: :::.::::::: ::.: . CCDS45 SCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYVFMEFCVEDSTDVHVLI 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 EKSKLTFSCLGGSDNFKHLNEIDLFHCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTK : ...::: ..:. . :::... .. .::. ::..::: : .:: . .:::::: CCDS45 EDHRIVFSC-KNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTK 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 ERAKLNWLSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPEVDGADDDSQDS : : ::::::.::.::: : . .... ....:...... . : .: : CCDS45 EDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP--PAMDDLDFTTTVV 140 150 160 170 180 190 160 pF1KB6 DDEKMPDLE CCDS45 SCCPAELQTEGSNGKKEVLSGFQVVLEDTVLFPEGGGQPDDRGTINDISVLRVTRRGEQA 200 210 220 230 240 250 >>CCDS11447.1 AARSD1 gene_id:100885850|Hs108|chr17 (525 aa) initn: 384 init1: 272 opt: 367 Z-score: 439.0 bits: 89.2 E(32554): 4e-18 Smith-Waterman score: 367; 40.3% identity (72.1% similar) in 129 aa overlap (17-145:1-126) 10 20 30 40 50 60 pF1KB6 MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCID .::::::: ::.: .: ...::: ..:. . :::... .. CCDS11 MEFCVEDSTDVHVLIEDHRIVFSC-KNADGVELYNEIEFYAKVN 10 20 30 40 70 80 90 100 110 120 pF1KB6 PNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNF .::. ::..::: : .:: . .::::::: : ::::::.::.::: : . .... CCDS11 SKDSQDKRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHV 50 60 70 80 90 100 130 140 150 160 pF1KB6 DRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE ....:...... . : .: : CCDS11 EHYAELLKKVSTKRPP--PAMDDLDFTTTVVSCCPAELQTEGSNGKKEVLSGFQVVLEDT 110 120 130 140 150 160 >>CCDS45692.1 PTGES3L gene_id:100885848|Hs108|chr17 (161 aa) initn: 324 init1: 277 opt: 317 Z-score: 387.2 bits: 77.9 E(32554): 3e-15 Smith-Waterman score: 317; 39.1% identity (72.7% similar) in 110 aa overlap (44-153:50-157) 20 30 40 50 60 70 pF1KB6 YVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDPNDSKHKRTDRSI .:. . :::... .. .::. ::..::: CCDS45 GRPQDLKIAAPAWNSKCHPGAGAAMARCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSI 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB6 LCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGD : .:: . .::::::: : ::::::.::.::: : . .... ....:...... CCDS45 TCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTK 80 90 100 110 120 130 140 150 160 pF1KB6 EDVDLPEVDGADDDSQDSDDEKMPDLE . : .: ::::...:: CCDS45 RPP--PAMDDLDDDSDSADDATSN 140 150 160 160 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:02:47 2016 done: Sat Nov 5 00:02:47 2016 Total Scan time: 1.630 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]