FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6814, 185 aa 1>>>pF1KB6814 185 - 185 aa - 185 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0608+/-0.000326; mu= 14.0328+/- 0.020 mean_var=60.6720+/-11.748, 0's: 0 Z-trim(115.4): 61 B-trim: 0 in 0/52 Lambda= 0.164657 statistics sampled from 25797 (25858) to 25797 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.303), width: 16 Scan time: 5.580 The best scores are: opt bits E(85289) XP_011529826 (OMIM: 613745) PREDICTED: anaphase-pr ( 185) 1261 307.6 7.6e-84 NP_001243637 (OMIM: 613745) anaphase-promoting com ( 185) 1261 307.6 7.6e-84 NP_001243635 (OMIM: 613745) anaphase-promoting com ( 185) 1261 307.6 7.6e-84 NP_055700 (OMIM: 613745) anaphase-promoting comple ( 185) 1261 307.6 7.6e-84 NP_001243636 (OMIM: 613745) anaphase-promoting com ( 185) 1261 307.6 7.6e-84 XP_016863129 (OMIM: 613745) PREDICTED: anaphase-pr ( 196) 1261 307.6 8e-84 NP_001243638 (OMIM: 613745) anaphase-promoting com ( 196) 1261 307.6 8e-84 XP_016863128 (OMIM: 613745) PREDICTED: anaphase-pr ( 219) 1261 307.6 8.8e-84 NP_001305296 (OMIM: 613745) anaphase-promoting com ( 219) 1261 307.6 8.8e-84 XP_016863127 (OMIM: 613745) PREDICTED: anaphase-pr ( 223) 1261 307.6 8.9e-84 XP_016863133 (OMIM: 613745) PREDICTED: anaphase-pr ( 114) 747 185.3 2.9e-47 NP_001243639 (OMIM: 613745) anaphase-promoting com ( 114) 747 185.3 2.9e-47 NP_001243640 (OMIM: 613745) anaphase-promoting com ( 114) 747 185.3 2.9e-47 XP_016863132 (OMIM: 613745) PREDICTED: anaphase-pr ( 152) 747 185.4 3.7e-47 XP_011529834 (OMIM: 613745) PREDICTED: anaphase-pr ( 110) 745 184.9 3.9e-47 XP_011529831 (OMIM: 613745) PREDICTED: anaphase-pr ( 148) 745 184.9 5e-47 XP_011529832 (OMIM: 613745) PREDICTED: anaphase-pr ( 126) 743 184.4 6.1e-47 XP_016863131 (OMIM: 613745) PREDICTED: anaphase-pr ( 153) 743 184.5 7.1e-47 XP_011529829 (OMIM: 613745) PREDICTED: anaphase-pr ( 157) 743 184.5 7.3e-47 XP_011529828 (OMIM: 613745) PREDICTED: anaphase-pr ( 164) 743 184.5 7.6e-47 XP_016863130 (OMIM: 613745) PREDICTED: anaphase-pr ( 176) 743 184.5 8e-47 XP_011529827 (OMIM: 613745) PREDICTED: anaphase-pr ( 180) 743 184.5 8.2e-47 NP_001243641 (OMIM: 613745) anaphase-promoting com ( 83) 477 121.1 4.5e-28 XP_011529833 (OMIM: 613745) PREDICTED: anaphase-pr ( 121) 477 121.2 6.2e-28 XP_011513323 (OMIM: 273750,609577) PREDICTED: cull ( 989) 168 48.3 4.4e-05 NP_055595 (OMIM: 273750,609577) cullin-7 isoform 2 (1698) 168 48.4 7e-05 XP_016867028 (OMIM: 273750,609577) PREDICTED: cull (1702) 168 48.5 7e-05 XP_016867027 (OMIM: 273750,609577) PREDICTED: cull (1711) 168 48.5 7e-05 XP_016867026 (OMIM: 273750,609577) PREDICTED: cull (1730) 168 48.5 7.1e-05 XP_006715348 (OMIM: 273750,609577) PREDICTED: cull (1734) 168 48.5 7.1e-05 XP_016867025 (OMIM: 273750,609577) PREDICTED: cull (1743) 168 48.5 7.1e-05 XP_005249560 (OMIM: 273750,609577) PREDICTED: cull (1750) 168 48.5 7.1e-05 XP_011513322 (OMIM: 273750,609577) PREDICTED: cull (1754) 168 48.5 7.2e-05 XP_016867024 (OMIM: 273750,609577) PREDICTED: cull (1763) 168 48.5 7.2e-05 NP_001161842 (OMIM: 273750,609577) cullin-7 isofor (1782) 168 48.5 7.3e-05 XP_011513321 (OMIM: 273750,609577) PREDICTED: cull (1786) 168 48.5 7.3e-05 XP_016867023 (OMIM: 273750,609577) PREDICTED: cull (1791) 168 48.5 7.3e-05 XP_016867022 (OMIM: 273750,609577) PREDICTED: cull (1795) 168 48.5 7.3e-05 XP_016878186 (OMIM: 176270,227220,605837,615516) P (2556) 165 47.8 0.00016 XP_016878187 (OMIM: 176270,227220,605837,615516) P (2556) 165 47.8 0.00016 XP_011520435 (OMIM: 176270,227220,605837,615516) P (3749) 165 47.9 0.00022 XP_011520433 (OMIM: 176270,227220,605837,615516) P (4673) 165 48.0 0.00027 XP_006720790 (OMIM: 176270,227220,605837,615516) P (4748) 165 48.0 0.00027 XP_005268333 (OMIM: 176270,227220,605837,615516) P (4796) 165 48.0 0.00027 XP_016878184 (OMIM: 176270,227220,605837,615516) P (4796) 165 48.0 0.00027 XP_016878185 (OMIM: 176270,227220,605837,615516) P (4796) 165 48.0 0.00027 XP_006720789 (OMIM: 176270,227220,605837,615516) P (4829) 165 48.0 0.00027 NP_004658 (OMIM: 176270,227220,605837,615516) E3 u (4834) 165 48.0 0.00027 XP_011512732 (OMIM: 607489) PREDICTED: cullin-9 is (1403) 153 44.8 0.0007 XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 is (1834) 153 44.9 0.00088 >>XP_011529826 (OMIM: 613745) PREDICTED: anaphase-promot (185 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1626.3 bits: 307.6 E(85289): 7.6e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185) 10 20 30 40 50 60 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM 130 140 150 160 170 180 pF1KB6 YRSIR ::::: XP_011 YRSIR >>NP_001243637 (OMIM: 613745) anaphase-promoting complex (185 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1626.3 bits: 307.6 E(85289): 7.6e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185) 10 20 30 40 50 60 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM 130 140 150 160 170 180 pF1KB6 YRSIR ::::: NP_001 YRSIR >>NP_001243635 (OMIM: 613745) anaphase-promoting complex (185 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1626.3 bits: 307.6 E(85289): 7.6e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185) 10 20 30 40 50 60 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM 130 140 150 160 170 180 pF1KB6 YRSIR ::::: NP_001 YRSIR >>NP_055700 (OMIM: 613745) anaphase-promoting complex su (185 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1626.3 bits: 307.6 E(85289): 7.6e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185) 10 20 30 40 50 60 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM 130 140 150 160 170 180 pF1KB6 YRSIR ::::: NP_055 YRSIR >>NP_001243636 (OMIM: 613745) anaphase-promoting complex (185 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1626.3 bits: 307.6 E(85289): 7.6e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185) 10 20 30 40 50 60 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM 130 140 150 160 170 180 pF1KB6 YRSIR ::::: NP_001 YRSIR >>XP_016863129 (OMIM: 613745) PREDICTED: anaphase-promot (196 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1625.9 bits: 307.6 E(85289): 8e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:12-196) 10 20 30 40 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDN ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGGVKETNILKMTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 LETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIR 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 QLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGK 130 140 150 160 170 180 170 180 pF1KB6 FPRCTTIDFMMYRSIR :::::::::::::::: XP_016 FPRCTTIDFMMYRSIR 190 >>NP_001243638 (OMIM: 613745) anaphase-promoting complex (196 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1625.9 bits: 307.6 E(85289): 8e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:12-196) 10 20 30 40 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDN ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGGVKETNILKMTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDN 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 LETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIR 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 QLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGK 130 140 150 160 170 180 170 180 pF1KB6 FPRCTTIDFMMYRSIR :::::::::::::::: NP_001 FPRCTTIDFMMYRSIR 190 >>XP_016863128 (OMIM: 613745) PREDICTED: anaphase-promot (219 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1625.2 bits: 307.6 E(85289): 8.8e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:35-219) 10 20 30 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAV :::::::::::::::::::::::::::::: XP_016 FLEWASYSLQNLEAIFLTLSSMVRAYNILKMTTPNKTPPGADPKQLERTGTVREIGSQAV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 WSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYT 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 PSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRD 130 140 150 160 170 180 160 170 180 pF1KB6 THMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR ::::::::::::::::::::::::::::::::::: XP_016 THMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR 190 200 210 >>NP_001305296 (OMIM: 613745) anaphase-promoting complex (219 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1625.2 bits: 307.6 E(85289): 8.8e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:35-219) 10 20 30 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAV :::::::::::::::::::::::::::::: NP_001 FLEWASYSLQNLEAIFLTLSSMVRAYNILKMTTPNKTPPGADPKQLERTGTVREIGSQAV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 WSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYT 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 PSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRD 130 140 150 160 170 180 160 170 180 pF1KB6 THMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR ::::::::::::::::::::::::::::::::::: NP_001 THMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR 190 200 210 >>XP_016863127 (OMIM: 613745) PREDICTED: anaphase-promot (223 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1625.1 bits: 307.6 E(85289): 8.9e-84 Smith-Waterman score: 1261; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:39-223) 10 20 30 pF1KB6 MTTPNKTPPGADPKQLERTGTVREIGSQAV :::::::::::::::::::::::::::::: XP_016 CSTPLAKPAAGGAENLSFGKQPGLETNILKMTTPNKTPPGADPKQLERTGTVREIGSQAV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 WSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYT 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 PSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRD 130 140 150 160 170 180 160 170 180 pF1KB6 THMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR ::::::::::::::::::::::::::::::::::: XP_016 THMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR 190 200 210 220 185 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:10:07 2016 done: Sat Nov 5 20:10:07 2016 Total Scan time: 5.580 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]