FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6816, 185 aa 1>>>pF1KB6816 185 - 185 aa - 185 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4842+/-0.000313; mu= 8.1945+/- 0.020 mean_var=98.7227+/-19.695, 0's: 0 Z-trim(118.2): 8 B-trim: 0 in 0/52 Lambda= 0.129082 statistics sampled from 30884 (30889) to 30884 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.362), width: 16 Scan time: 5.260 The best scores are: opt bits E(85289) NP_001881 (OMIM: 115450) alpha-S1-casein isoform 1 ( 185) 1243 241.0 8.2e-64 XP_006714152 (OMIM: 115450) PREDICTED: alpha-S1-ca ( 184) 1224 237.5 9.5e-63 XP_006714153 (OMIM: 115450) PREDICTED: alpha-S1-ca ( 177) 1167 226.8 1.4e-59 XP_006714154 (OMIM: 115450) PREDICTED: alpha-S1-ca ( 176) 826 163.3 1.9e-40 NP_001020275 (OMIM: 115450) alpha-S1-casein isofor ( 176) 824 163.0 2.4e-40 >>NP_001881 (OMIM: 115450) alpha-S1-casein isoform 1 pre (185 aa) initn: 1243 init1: 1243 opt: 1243 Z-score: 1266.6 bits: 241.0 E(85289): 8.2e-64 Smith-Waterman score: 1243; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185) 10 20 30 40 50 60 pF1KB6 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN 130 140 150 160 170 180 pF1KB6 VMLQW ::::: NP_001 VMLQW >>XP_006714152 (OMIM: 115450) PREDICTED: alpha-S1-casein (184 aa) initn: 902 init1: 902 opt: 1224 Z-score: 1247.5 bits: 237.5 E(85289): 9.5e-63 Smith-Waterman score: 1224; 99.5% identity (99.5% similar) in 185 aa overlap (1-185:1-184) 10 20 30 40 50 60 pF1KB6 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_006 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNR-RNILREKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN 120 130 140 150 160 170 pF1KB6 VMLQW ::::: XP_006 VMLQW 180 >>XP_006714153 (OMIM: 115450) PREDICTED: alpha-S1-casein (177 aa) initn: 787 init1: 787 opt: 1167 Z-score: 1190.4 bits: 226.8 E(85289): 1.4e-59 Smith-Waterman score: 1167; 95.7% identity (95.7% similar) in 185 aa overlap (1-185:1-177) 10 20 30 40 50 60 pF1KB6 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ ::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TDEIK--------NCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN 120 130 140 150 160 170 pF1KB6 VMLQW ::::: XP_006 VMLQW >>XP_006714154 (OMIM: 115450) PREDICTED: alpha-S1-casein (176 aa) initn: 1102 init1: 780 opt: 826 Z-score: 847.3 bits: 163.3 E(85289): 1.9e-40 Smith-Waterman score: 1148; 95.1% identity (95.1% similar) in 185 aa overlap (1-185:1-176) 10 20 30 40 50 60 pF1KB6 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_006 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNR-RNILREKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ ::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TDEIK--------NCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN 120 130 140 150 160 170 pF1KB6 VMLQW ::::: XP_006 VMLQW >>NP_001020275 (OMIM: 115450) alpha-S1-casein isoform 2 (176 aa) initn: 927 init1: 605 opt: 824 Z-score: 845.2 bits: 163.0 E(85289): 2.4e-40 Smith-Waterman score: 1146; 95.1% identity (95.1% similar) in 185 aa overlap (1-185:1-176) 10 20 30 40 50 60 pF1KB6 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ ::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: NP_001 MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNR-RNILREKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQ ::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 TDEIKDTRNESTQNCVVAEPEKMESSISSSSEE--------QFCRLNEYNQLQLQAAHAQ 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNN 120 130 140 150 160 170 pF1KB6 VMLQW ::::: NP_001 VMLQW 185 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:14:11 2016 done: Sat Nov 5 04:14:11 2016 Total Scan time: 5.260 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]