FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6820, 186 aa 1>>>pF1KB6820 186 - 186 aa - 186 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0424+/-0.000936; mu= 14.5882+/- 0.057 mean_var=81.5978+/-17.381, 0's: 0 Z-trim(106.1): 176 B-trim: 778 in 2/48 Lambda= 0.141983 statistics sampled from 8601 (8818) to 8601 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.271), width: 16 Scan time: 1.890 The best scores are: opt bits E(32554) CCDS2566.1 ARL8B gene_id:55207|Hs108|chr3 ( 186) 1243 264.0 3.7e-71 CCDS1421.1 ARL8A gene_id:127829|Hs108|chr1 ( 186) 1182 251.5 2.2e-67 CCDS73004.1 ARL8A gene_id:127829|Hs108|chr1 ( 147) 785 170.1 5.5e-43 CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 ( 175) 418 95.0 2.7e-20 CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 ( 181) 402 91.7 2.6e-19 CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 ( 181) 399 91.1 4e-19 CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 ( 181) 399 91.1 4e-19 CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 ( 180) 387 88.7 2.2e-18 CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 ( 180) 372 85.6 1.9e-17 CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 ( 182) 370 85.2 2.5e-17 CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 ( 184) 365 84.2 5.1e-17 CCDS2925.1 ARL13B gene_id:200894|Hs108|chr3 ( 428) 358 83.1 2.5e-16 CCDS9419.1 ARL11 gene_id:115761|Hs108|chr13 ( 196) 345 80.1 9.2e-16 CCDS2928.1 ARL6 gene_id:84100|Hs108|chr3 ( 186) 329 76.8 8.6e-15 CCDS2512.1 ARL4C gene_id:10123|Hs108|chr2 ( 192) 328 76.6 1e-14 CCDS63169.1 ARL4C gene_id:10123|Hs108|chr2 ( 201) 328 76.6 1e-14 CCDS5359.1 ARL4A gene_id:10124|Hs108|chr7 ( 200) 325 76.0 1.6e-14 CCDS3192.1 ARL14 gene_id:80117|Hs108|chr3 ( 192) 323 75.6 2.1e-14 CCDS11463.1 ARL4D gene_id:379|Hs108|chr17 ( 201) 321 75.2 2.8e-14 CCDS73510.1 ARL1 gene_id:400|Hs108|chr12 ( 135) 318 74.4 3.2e-14 CCDS3987.1 TRIM23 gene_id:373|Hs108|chr5 ( 574) 315 74.4 1.4e-13 CCDS2195.1 ARL5A gene_id:26225|Hs108|chr2 ( 179) 307 72.3 1.9e-13 CCDS4400.1 ARL10 gene_id:285598|Hs108|chr5 ( 244) 307 72.4 2.4e-13 CCDS3986.1 TRIM23 gene_id:373|Hs108|chr5 ( 546) 309 73.1 3.2e-13 CCDS43322.1 TRIM23 gene_id:373|Hs108|chr5 ( 569) 305 72.3 5.8e-13 CCDS13533.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 201) 299 70.7 6.4e-13 CCDS7131.1 ARL5B gene_id:221079|Hs108|chr10 ( 179) 295 69.8 1e-12 CCDS4177.1 SAR1B gene_id:51128|Hs108|chr5 ( 198) 294 69.7 1.3e-12 CCDS46630.1 ARFRP1 gene_id:10139|Hs108|chr20 ( 173) 291 69.0 1.8e-12 CCDS54850.1 ARL15 gene_id:54622|Hs108|chr5 ( 204) 286 68.0 4.1e-12 CCDS7298.1 SAR1A gene_id:56681|Hs108|chr10 ( 198) 269 64.5 4.5e-11 CCDS45664.1 ARL5C gene_id:390790|Hs108|chr17 ( 179) 266 63.9 6.4e-11 >>CCDS2566.1 ARL8B gene_id:55207|Hs108|chr3 (186 aa) initn: 1243 init1: 1243 opt: 1243 Z-score: 1390.9 bits: 264.0 E(32554): 3.7e-71 Smith-Waterman score: 1243; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH 130 140 150 160 170 180 pF1KB6 SKSRRS :::::: CCDS25 SKSRRS >>CCDS1421.1 ARL8A gene_id:127829|Hs108|chr1 (186 aa) initn: 1182 init1: 1182 opt: 1182 Z-score: 1323.4 bits: 251.5 E(32554): 2.2e-67 Smith-Waterman score: 1182; 91.9% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV :.::...:::::..:::::::::::::::::::::::::::::::.:::::::::::::. CCDS14 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL ::::::::.::::::::::::::::::::.:::::.::::.::::::.:::::::::::: CCDS14 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH :::::::::::::::.:::::.:::::::::::::::::::::::::::::::::::::: CCDS14 QGIPVLVLGNKRDLPGALDEKELIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH 130 140 150 160 170 180 pF1KB6 SKSRRS :::::: CCDS14 SKSRRS >>CCDS73004.1 ARL8A gene_id:127829|Hs108|chr1 (147 aa) initn: 783 init1: 783 opt: 785 Z-score: 885.2 bits: 170.1 E(32554): 5.5e-43 Smith-Waterman score: 785; 85.2% identity (95.6% similar) in 135 aa overlap (1-134:1-135) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV :.::...:::::..:::::::::::::::::::::::::::::::.:::::::::::::. CCDS73 MIALFNKLLDWFKALFWKEEMELTLVGLQYSGKTTFVNVIASGQFNEDMIPTVGFNMRKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL ::::::::.::::::::::::::::::::.:::::.::::.::::::.:::::::::::: CCDS73 TKGNVTIKLWDIGGQPRFRSMWERYCRGVSAIVYMVDAADQEKIEASKNELHNLLDKPQL 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 QGIPVLVLG-NKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQ :::: : . ::: CCDS73 QGIPESVCHPGPRDLLLLHLLQRKGQH 130 140 >>CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 (175 aa) initn: 415 init1: 358 opt: 418 Z-score: 477.9 bits: 95.0 E(32554): 2.7e-20 Smith-Waterman score: 418; 36.5% identity (72.9% similar) in 170 aa overlap (15-183:8-175) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV .: ..::.. ..::. .::::.. . :: : :::::::.. : CCDS96 MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQ-SVTTIPTVGFNVETV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL : :: ...::.::: ..: .:..: :........: :::..:. .:.::: ... .. CCDS96 TYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREM 60 70 80 90 100 110 130 140 150 160 170 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEK-DNIDITLQWLIQ . .:...::.:::.:. ... ::..:. :.::. :: . :.. : :: . CCDS96 RDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQP-SCATSGDGLYEGLTWLTS 120 130 140 150 160 170 180 pF1KB6 HSKSRRS . :: CCDS96 NYKS >>CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 (181 aa) initn: 401 init1: 325 opt: 402 Z-score: 460.0 bits: 91.7 E(32554): 2.6e-19 Smith-Waterman score: 402; 31.6% identity (72.4% similar) in 174 aa overlap (12-185:9-181) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV :..:: :.::.. .:::. .::::.. . :.. :::.:::.. : CCDS15 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL :... .::.::: ..: .:..: ..........:. :::... .:.:: .: . .: CCDS15 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH . .::..::.:::::.. .. .:..: ... :. . :.. :.:: .. CCDS15 RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQ 120 130 140 150 160 170 pF1KB6 SKSRRS .... CCDS15 LRNQK 180 >>CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 (181 aa) initn: 391 init1: 338 opt: 399 Z-score: 456.7 bits: 91.1 E(32554): 4e-19 Smith-Waterman score: 399; 32.8% identity (71.8% similar) in 174 aa overlap (12-185:9-181) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV : ::: .::.. ..::. .::::.. . :. :::.:::.. : CCDS44 MGGFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTT-IPTIGFNVETV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL : :. ...::.::: .: .:. : ...:..:..:. ::..: :..:: .:.. .: CCDS44 TYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEEL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH . ..:..::.:. .:. ... ....: :..::. .. : . ..: ...::.. CCDS44 RKAILVVFANKQDMEQAMTSSEMANSLGLPALKDRKWQIFKTSATKGTGLDEAMEWLVET 120 130 140 150 160 170 pF1KB6 SKSRRS :::. CCDS44 LKSRQ 180 >>CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 (181 aa) initn: 401 init1: 335 opt: 399 Z-score: 456.7 bits: 91.1 E(32554): 4e-19 Smith-Waterman score: 399; 31.6% identity (72.4% similar) in 174 aa overlap (12-185:9-181) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV ..::. :.::.. .:::. .::::.. . :.. :::.:::.. : CCDS87 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL :... .::.::: ..: .:..: ..........:. :::... .:.:: .: . .: CCDS87 EYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDEL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH . .::..::.:::::.. .. .:..: ... :. . :.. :.:: .. CCDS87 RDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQ 120 130 140 150 160 170 pF1KB6 SKSRRS :... CCDS87 LKNKK 180 >>CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 (180 aa) initn: 344 init1: 316 opt: 387 Z-score: 443.5 bits: 88.7 E(32554): 2.2e-18 Smith-Waterman score: 387; 31.6% identity (71.3% similar) in 174 aa overlap (12-185:9-180) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV : .: :..:.. .:::. .::::.. . :.. :::.:::.. : CCDS34 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL :. . .::.::: ..: .:..: ..........:. :::... : .::...:.. .: CCDS34 EYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDEL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH . .::..::.:.:::. ..: .:..:. ...: . . .. :.:: .: CCDS34 RDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWL-SH 120 130 140 150 160 170 pF1KB6 SKSRRS :.: CCDS34 ELSKR 180 >>CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 (180 aa) initn: 373 init1: 306 opt: 372 Z-score: 426.9 bits: 85.6 E(32554): 1.9e-17 Smith-Waterman score: 372; 31.2% identity (70.5% similar) in 173 aa overlap (12-184:9-180) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV : :: :..:.. .:::. .::::.. . :.. :::.:::.. : CCDS28 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTT-IPTIGFNVETV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL :. . .::.::: :.: .:..: ..........:. :::.:. .::...: .: CCDS28 EYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDEL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH . .:...::.:::::. ... .:..:.....: . . .. :.:: .. CCDS28 RDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNE 120 130 140 150 160 170 pF1KB6 SKSRRS ..: CCDS28 LSKR 180 >>CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 (182 aa) initn: 338 init1: 303 opt: 370 Z-score: 424.6 bits: 85.2 E(32554): 2.5e-17 Smith-Waterman score: 370; 32.9% identity (74.9% similar) in 167 aa overlap (19-185:16-181) 10 20 30 40 50 60 pF1KB6 MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKV .:... :.::. .::::... .:: ..:. . :: :::...: CCDS75 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISH-ITPTQGFNIKSV 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQL . . ...:::::: ..: .:. : .... ..:.::.:::...: . .:: .::.. .: CCDS75 QSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQH . .:::...::.:: .: ... : .:: .:.:: : : .... ..:. .. CCDS75 SCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKN 120 130 140 150 160 170 pF1KB6 SKSRRS .... CCDS75 VNAKKK 180 186 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:04:56 2016 done: Sat Nov 5 04:04:57 2016 Total Scan time: 1.890 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]