FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6822, 186 aa 1>>>pF1KB6822 186 - 186 aa - 186 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1360+/-0.000347; mu= 8.6745+/- 0.022 mean_var=79.6880+/-15.936, 0's: 0 Z-trim(115.0): 13 B-trim: 0 in 0/53 Lambda= 0.143674 statistics sampled from 25140 (25152) to 25140 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.295), width: 16 Scan time: 5.900 The best scores are: opt bits E(85289) NP_009165 (OMIM: 607387) dynactin subunit 3 isofor ( 186) 1181 254.0 1e-67 NP_077324 (OMIM: 607387) dynactin subunit 3 isofor ( 176) 876 190.8 1e-48 NP_001268356 (OMIM: 607387) dynactin subunit 3 iso ( 176) 872 190.0 1.8e-48 NP_001268355 (OMIM: 607387) dynactin subunit 3 iso ( 154) 866 188.7 3.8e-48 NP_001268354 (OMIM: 607387) dynactin subunit 3 iso ( 158) 573 128.0 7.5e-30 >>NP_009165 (OMIM: 607387) dynactin subunit 3 isoform 1 (186 aa) initn: 1181 init1: 1181 opt: 1181 Z-score: 1336.9 bits: 254.0 E(85289): 1e-67 Smith-Waterman score: 1181; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186) 10 20 30 40 50 60 pF1KB6 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQ 130 140 150 160 170 180 pF1KB6 VKPAEE :::::: NP_009 VKPAEE >>NP_077324 (OMIM: 607387) dynactin subunit 3 isoform 2 (176 aa) initn: 866 init1: 866 opt: 876 Z-score: 995.6 bits: 190.8 E(85289): 1e-48 Smith-Waterman score: 876; 91.6% identity (95.5% similar) in 154 aa overlap (1-153:1-154) 10 20 30 40 50 60 pF1KB6 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_077 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EHAARLQRLAQIHIQQQ-DQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAAT ::::::::::::::::: : . .:. .:.:. NP_077 EHAARLQRLAQIHIQQQAPWGVGVRDEAGSLVEDVGFAQFLSVLHFGPTGPVCGNH 130 140 150 160 170 180 pF1KB6 QVKPAEE >>NP_001268356 (OMIM: 607387) dynactin subunit 3 isoform (176 aa) initn: 872 init1: 872 opt: 872 Z-score: 991.1 bits: 190.0 E(85289): 1.8e-48 Smith-Waterman score: 1033; 90.9% identity (92.5% similar) in 186 aa overlap (1-186:1-176) 10 20 30 40 50 60 pF1KB6 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQ ::::::::::::::::: . .: ::.: :::::::::::::::::::::: NP_001 EHAARLQRLAQIHIQQQIPILTLT---------YNQT-MLLSKQFVQWDELLCQLEAATQ 130 140 150 160 170 pF1KB6 VKPAEE :::::: NP_001 VKPAEE >>NP_001268355 (OMIM: 607387) dynactin subunit 3 isoform (154 aa) initn: 866 init1: 866 opt: 866 Z-score: 985.3 bits: 188.7 E(85289): 3.8e-48 Smith-Waterman score: 866; 100.0% identity (100.0% similar) in 137 aa overlap (1-137:1-137) 10 20 30 40 50 60 pF1KB6 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQ ::::::::::::::::: NP_001 EHAARLQRLAQIHIQQQFLSVLHFGPTGPVCGNH 130 140 150 >>NP_001268354 (OMIM: 607387) dynactin subunit 3 isoform (158 aa) initn: 582 init1: 566 opt: 573 Z-score: 656.9 bits: 128.0 E(85289): 7.5e-30 Smith-Waterman score: 945; 84.9% identity (84.9% similar) in 186 aa overlap (1-186:1-158) 10 20 30 40 50 60 pF1KB6 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP ::::::::::::::::::::::::::::: ::: NP_001 IEDLIKYLDPEYIDRIAIPDASKLQFILA----------------------------AVP 70 80 90 130 140 150 160 170 180 pF1KB6 EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAATQ 100 110 120 130 140 150 pF1KB6 VKPAEE :::::: NP_001 VKPAEE 186 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:27:03 2016 done: Sat Nov 5 00:27:04 2016 Total Scan time: 5.900 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]