FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6824, 187 aa 1>>>pF1KB6824 187 - 187 aa - 187 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5396+/-0.000988; mu= 11.7957+/- 0.060 mean_var=72.7914+/-14.544, 0's: 0 Z-trim(105.4): 93 B-trim: 0 in 0/50 Lambda= 0.150326 statistics sampled from 8307 (8405) to 8307 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.258), width: 16 Scan time: 1.850 The best scores are: opt bits E(32554) CCDS10296.1 CIB2 gene_id:10518|Hs108|chr15 ( 187) 1243 278.6 1.5e-75 CCDS61722.1 CIB2 gene_id:10518|Hs108|chr15 ( 144) 950 215.0 1.7e-56 CCDS12340.1 CIB3 gene_id:117286|Hs108|chr19 ( 187) 820 186.9 6.3e-48 CCDS61723.1 CIB2 gene_id:10518|Hs108|chr15 ( 138) 804 183.3 5.4e-47 CCDS74305.1 CIB3 gene_id:117286|Hs108|chr19 ( 138) 541 126.3 8.1e-30 CCDS10360.1 CIB1 gene_id:10519|Hs108|chr15 ( 191) 447 106.0 1.4e-23 CCDS33160.1 CIB4 gene_id:130106|Hs108|chr2 ( 185) 415 99.0 1.7e-21 CCDS73781.1 CIB1 gene_id:10519|Hs108|chr15 ( 231) 376 90.6 7.3e-19 CCDS46310.1 PPP3R1 gene_id:5534|Hs108|chr2 ( 170) 263 66.1 1.4e-11 >>CCDS10296.1 CIB2 gene_id:10518|Hs108|chr15 (187 aa) initn: 1243 init1: 1243 opt: 1243 Z-score: 1469.7 bits: 278.6 E(32554): 1.5e-75 Smith-Waterman score: 1243; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187) 10 20 30 40 50 60 pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL 130 140 150 160 170 180 pF1KB6 STFHIRI ::::::: CCDS10 STFHIRI >>CCDS61722.1 CIB2 gene_id:10518|Hs108|chr15 (144 aa) initn: 950 init1: 950 opt: 950 Z-score: 1127.9 bits: 215.0 E(32554): 1.7e-56 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 144 aa overlap (44-187:1-144) 20 30 40 50 60 70 pF1KB6 DNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKER :::::::::::::::::::::::::::::: CCDS61 MDYRKSPIVHVPMSLIIQMPELRENPFKER 10 20 30 80 90 100 110 120 130 pF1KB6 IVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 IVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLA 40 50 60 70 80 90 140 150 160 170 180 pF1KB6 RLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 RLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI 100 110 120 130 140 >>CCDS12340.1 CIB3 gene_id:117286|Hs108|chr19 (187 aa) initn: 820 init1: 820 opt: 820 Z-score: 973.9 bits: 186.9 E(32554): 6.3e-48 Smith-Waterman score: 820; 61.5% identity (87.2% similar) in 187 aa overlap (1-187:1-187) 10 20 30 40 50 60 pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII ::::::.::.:::. :::::::..:.:..: :. .:::.:::.:: : :.::. :: CCDS12 MGNKQTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKVPYELIG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD .::::..:::..::. .:::::.:..:...:.:::::. : :::.::: :::::::::.: CCDS12 SMPELKDNPFRQRIAQVFSEDGDGHMTLDNFLDMFSVMSEMAPRDLKAYYAFKIYDFNND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL ..:: ::: :...::.. :. ::: :::.::..::: : ::.:.. ::..:: .::::: CCDS12 DYICAWDLEQTVTKLTRGGLSAEEVSLVCEKVLDEADGDHDGRLSLEDFQNMILRAPDFL 130 140 150 160 170 180 pF1KB6 STFHIRI ::::::: CCDS12 STFHIRI >>CCDS61723.1 CIB2 gene_id:10518|Hs108|chr15 (138 aa) initn: 804 init1: 804 opt: 804 Z-score: 957.1 bits: 183.3 E(32554): 5.4e-47 Smith-Waterman score: 804; 96.1% identity (98.4% similar) in 127 aa overlap (61-187:12-138) 40 50 60 70 80 90 pF1KB6 HSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVAAFSEDGEGNLTFND :. . .:::::::::::::::::::::::: CCDS61 MGNKQTIFTEEQLDNYQENPFKERIVAAFSEDGEGNLTFND 10 20 30 40 100 110 120 130 140 150 pF1KB6 FVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 FVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCD 50 60 70 80 90 100 160 170 180 pF1KB6 KVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI ::::::::::::::::::::::::::::::::::::: CCDS61 KVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI 110 120 130 >>CCDS74305.1 CIB3 gene_id:117286|Hs108|chr19 (138 aa) initn: 541 init1: 541 opt: 541 Z-score: 648.8 bits: 126.3 E(32554): 8.1e-30 Smith-Waterman score: 541; 59.8% identity (86.6% similar) in 127 aa overlap (61-187:12-138) 40 50 60 70 80 90 pF1KB6 HSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVAAFSEDGEGNLTFND :. ..:::..::. .:::::.:..:... CCDS74 MGNKQTVFTHEQLEAYQDNPFRQRIAQVFSEDGDGHMTLDN 10 20 30 40 100 110 120 130 140 150 pF1KB6 FVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCD :.:::::. : :::.::: :::::::::.:..:: ::: :...::.. :. ::: :::. CCDS74 FLDMFSVMSEMAPRDLKAYYAFKIYDFNNDDYICAWDLEQTVTKLTRGGLSAEEVSLVCE 50 60 70 80 90 100 160 170 180 pF1KB6 KVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI ::..::: : ::.:.. ::..:: .:::::::::::: CCDS74 KVLDEADGDHDGRLSLEDFQNMILRAPDFLSTFHIRI 110 120 130 >>CCDS10360.1 CIB1 gene_id:10519|Hs108|chr15 (191 aa) initn: 284 init1: 185 opt: 447 Z-score: 536.6 bits: 106.0 E(32554): 1.4e-23 Smith-Waterman score: 447; 37.9% identity (73.7% similar) in 190 aa overlap (1-185:1-189) 10 20 30 40 50 60 pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII ::.. . ...: : .::: ::..:..:: : :: :: :. . ..: ..::. :. CCDS10 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQE-QRSVESSLRAQVPFEQIL 10 20 30 40 50 70 80 90 100 110 pF1KB6 QMPELRENPFKERIVAAFSED-GEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNT ..:::. ::::::: .:: . .. .:.:.::.:..::. ..: ..:..:::.:.::. CCDS10 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 DNFICKEDLELTLARLT----KSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAK :. . .::: . :: ..:. :. . :...::.:.: :: .....:. .:.. CCDS10 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 120 130 140 150 160 170 180 pF1KB6 APDFLSTFHIRI .::: :.:.: CCDS10 SPDFASSFKIVL 180 190 >>CCDS33160.1 CIB4 gene_id:130106|Hs108|chr2 (185 aa) initn: 357 init1: 129 opt: 415 Z-score: 499.3 bits: 99.0 E(32554): 1.7e-21 Smith-Waterman score: 415; 39.8% identity (72.2% similar) in 176 aa overlap (11-185:12-180) 10 20 30 40 50 pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLI :.:..:: ::.....:: .:. : .: : : : : . :. . CCDS33 MGQCLRYQMHWEDLEEYQALTFLTRNEILCIHDTFLKLCP---PGKYYKEAT--LTMDQV 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 IQMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNT ..: :: :::..:: .::. .: ..:.: . : ::. :.: :: .:::.::::: CCDS33 SSLPALRVNPFRDRICRVFSH--KGMFSFEDVLGMASVFSEQACPSLKIEYAFRIYDFNE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 DNFICKEDLELTLARLTKSE-LDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPD ..:: .:::. . :: .:. ..:. .. . ..:. :.:::.:. :.:..:: .::.:: CCDS33 NGFIDEEDLQRIILRLLNSDDMSEDLLMDLTNHVLSESDLDNDNMLSFSEFEHAMAKSPD 120 130 140 150 160 170 180 pF1KB6 FLSTFHIRI :...:.: CCDS33 FMNSFRIHFWGC 180 >>CCDS73781.1 CIB1 gene_id:10519|Hs108|chr15 (231 aa) initn: 421 init1: 151 opt: 376 Z-score: 452.1 bits: 90.6 E(32554): 7.3e-19 Smith-Waterman score: 376; 37.0% identity (72.8% similar) in 162 aa overlap (29-185:69-229) 10 20 30 40 50 pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSL . : :: :: :. . ..: ..::. CCDS73 LVDNEQQARSGNEHTGRPIAENTDSSPLSTRAHRRFCELLPQE-QRSVESSLRAQVPFEQ 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB6 IIQMPELRENPFKERIVAAFSED-GEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDF :...:::. ::::::: .:: . .. .:.:.::.:..::. ..: ..:..:::.:.:: CCDS73 ILSLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDF 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB6 NTDNFICKEDLELTLARLT----KSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMI . :. . .::: . :: ..:. :. . :...::.:.: :: .....:. .: CCDS73 DDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 160 170 180 190 200 210 180 pF1KB6 AKAPDFLSTFHIRI ...::: :.:.: CCDS73 SRSPDFASSFKIVL 220 230 >>CCDS46310.1 PPP3R1 gene_id:5534|Hs108|chr2 (170 aa) initn: 329 init1: 258 opt: 263 Z-score: 321.6 bits: 66.1 E(32554): 1.4e-11 Smith-Waterman score: 289; 32.5% identity (64.9% similar) in 151 aa overlap (19-169:12-153) 10 20 30 40 50 60 pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII :. :. .: .: .:: .: .: : :. ::: CCDS46 MGNEASYPLEMCSHFDADEIKRLGKRFKKL-----DLDNSGSLSVEEFMSL-- 10 20 30 40 70 80 90 100 110 120 pF1KB6 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD :::..::. .:.. :. ::.:.. :..:.. : . .. .: : .::.:::.. : CCDS46 --PELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL ..: . .: .: .. ..: . .. . ::.: .:: ::::...: .: CCDS46 GYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHK 110 120 130 140 150 160 pF1KB6 STFHIRI CCDS46 KMVVDV 170 187 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:23:38 2016 done: Fri Nov 4 14:23:39 2016 Total Scan time: 1.850 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]