FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6824, 187 aa
1>>>pF1KB6824 187 - 187 aa - 187 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0644+/-0.000443; mu= 14.8320+/- 0.028
mean_var=81.8794+/-16.731, 0's: 0 Z-trim(112.4): 159 B-trim: 597 in 1/50
Lambda= 0.141738
statistics sampled from 21144 (21364) to 21144 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.25), width: 16
Scan time: 5.280
The best scores are: opt bits E(85289)
NP_006374 (OMIM: 605564,609439,614869) calcium and ( 187) 1243 263.6 1.3e-70
XP_005254183 (OMIM: 605564,609439,614869) PREDICTE ( 210) 1210 256.9 1.5e-68
NP_001288153 (OMIM: 605564,609439,614869) calcium ( 192) 960 205.8 3.4e-53
XP_006720437 (OMIM: 605564,609439,614869) PREDICTE ( 144) 950 203.6 1.2e-52
NP_001258817 (OMIM: 605564,609439,614869) calcium ( 144) 950 203.6 1.2e-52
XP_011519463 (OMIM: 605564,609439,614869) PREDICTE ( 167) 917 196.9 1.4e-50
NP_473454 (OMIM: 610645) calcium and integrin-bind ( 187) 820 177.2 1.4e-44
NP_001258818 (OMIM: 605564,609439,614869) calcium ( 138) 804 173.8 1.1e-43
NP_001287851 (OMIM: 610645) calcium and integrin-b ( 138) 541 120.0 1.7e-27
NP_006375 (OMIM: 602293) calcium and integrin-bind ( 191) 447 100.9 1.3e-21
XP_006720438 (OMIM: 602293) PREDICTED: calcium and ( 264) 429 97.3 2.1e-20
NP_001025052 (OMIM: 610646) calcium and integrin-b ( 185) 415 94.3 1.2e-19
XP_011530816 (OMIM: 610646) PREDICTED: calcium and ( 201) 397 90.7 1.6e-18
NP_001264693 (OMIM: 602293) calcium and integrin-b ( 231) 376 86.4 3.5e-17
XP_016858818 (OMIM: 610646) PREDICTED: calcium and ( 162) 371 85.3 5.5e-17
XP_011530819 (OMIM: 610646) PREDICTED: calcium and ( 187) 338 78.6 6.6e-15
XP_016858819 (OMIM: 610646) PREDICTED: calcium and ( 140) 324 75.6 3.9e-14
NP_000936 (OMIM: 601302) calcineurin subunit B typ ( 170) 263 63.2 2.5e-10
NP_671709 (OMIM: 613821) calcineurin subunit B typ ( 173) 246 59.7 2.9e-09
NP_009167 (OMIM: 606988) calcineurin B homologous ( 195) 200 50.4 2.1e-06
NP_001030086 (OMIM: 604662) calsenilin isoform 2 p ( 230) 197 49.8 3.6e-06
NP_038462 (OMIM: 604662) calsenilin isoform 1 [Hom ( 256) 197 49.9 3.9e-06
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 180 46.1 2.4e-05
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 180 46.1 2.4e-05
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 180 46.1 2.4e-05
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 180 46.1 2.4e-05
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 180 46.1 2.4e-05
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 180 46.1 2.4e-05
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 180 46.1 2.4e-05
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 180 46.2 3e-05
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 180 46.2 3e-05
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 180 46.2 3e-05
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 180 46.2 3e-05
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 180 46.2 3e-05
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 180 46.3 3.6e-05
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 178 45.8 3.9e-05
XP_016859440 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
XP_011508648 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
XP_005246218 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
XP_016859441 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
NP_002140 (OMIM: 600207) hippocalcin-like protein ( 193) 171 44.5 0.00013
XP_005246220 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
XP_016859439 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
NP_001245286 (OMIM: 600207) hippocalcin-like prote ( 193) 171 44.5 0.00013
XP_005246219 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
XP_005246217 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
NP_001245288 (OMIM: 600207) hippocalcin-like prote ( 193) 171 44.5 0.00013
XP_011508650 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
XP_016859442 (OMIM: 600207) PREDICTED: hippocalcin ( 193) 171 44.5 0.00013
NP_001245287 (OMIM: 600207) hippocalcin-like prote ( 193) 171 44.5 0.00013
>>NP_006374 (OMIM: 605564,609439,614869) calcium and int (187 aa)
initn: 1243 init1: 1243 opt: 1243 Z-score: 1388.8 bits: 263.6 E(85289): 1.3e-70
Smith-Waterman score: 1243; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187)
10 20 30 40 50 60
pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL
130 140 150 160 170 180
pF1KB6 STFHIRI
:::::::
NP_006 STFHIRI
>>XP_005254183 (OMIM: 605564,609439,614869) PREDICTED: c (210 aa)
initn: 1261 init1: 1210 opt: 1210 Z-score: 1351.7 bits: 256.9 E(85289): 1.5e-68
Smith-Waterman score: 1210; 97.8% identity (97.8% similar) in 186 aa overlap (1-186:1-186)
10 20 30 40 50 60
pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL
130 140 150 160 170 180
pF1KB6 STFHIRI
: :
XP_005 RCCHYRGRAWAGQSRAGRDVGAEAPITRYL
190 200 210
>>NP_001288153 (OMIM: 605564,609439,614869) calcium and (192 aa)
initn: 988 init1: 801 opt: 960 Z-score: 1075.9 bits: 205.8 E(85289): 3.4e-53
Smith-Waterman score: 960; 80.7% identity (84.4% similar) in 192 aa overlap (1-187:1-192)
10 20 30 40 50 60
pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
::::::::::::::::::::::::::::: .: : . . .. : :
NP_001 MGNKQTIFTEEQLDNYQDCTFFNKKDILKWGNRGSEGFGHSSRVTQAVHSLAPGPSCLSC
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 QMPE-----LRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIY
. :.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THSDCCVCFLQENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 DFNTDNFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFNTDNFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAK
130 140 150 160 170 180
180
pF1KB6 APDFLSTFHIRI
::::::::::::
NP_001 APDFLSTFHIRI
190
>>XP_006720437 (OMIM: 605564,609439,614869) PREDICTED: c (144 aa)
initn: 950 init1: 950 opt: 950 Z-score: 1066.5 bits: 203.6 E(85289): 1.2e-52
Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 144 aa overlap (44-187:1-144)
20 30 40 50 60 70
pF1KB6 DNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKER
::::::::::::::::::::::::::::::
XP_006 MDYRKSPIVHVPMSLIIQMPELRENPFKER
10 20 30
80 90 100 110 120 130
pF1KB6 IVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLA
40 50 60 70 80 90
140 150 160 170 180
pF1KB6 RLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
100 110 120 130 140
>>NP_001258817 (OMIM: 605564,609439,614869) calcium and (144 aa)
initn: 950 init1: 950 opt: 950 Z-score: 1066.5 bits: 203.6 E(85289): 1.2e-52
Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 144 aa overlap (44-187:1-144)
20 30 40 50 60 70
pF1KB6 DNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKER
::::::::::::::::::::::::::::::
NP_001 MDYRKSPIVHVPMSLIIQMPELRENPFKER
10 20 30
80 90 100 110 120 130
pF1KB6 IVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLA
40 50 60 70 80 90
140 150 160 170 180
pF1KB6 RLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
100 110 120 130 140
>>XP_011519463 (OMIM: 605564,609439,614869) PREDICTED: c (167 aa)
initn: 968 init1: 917 opt: 917 Z-score: 1029.2 bits: 196.9 E(85289): 1.4e-50
Smith-Waterman score: 917; 97.2% identity (97.2% similar) in 143 aa overlap (44-186:1-143)
20 30 40 50 60 70
pF1KB6 DNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKER
::::::::::::::::::::::::::::::
XP_011 MDYRKSPIVHVPMSLIIQMPELRENPFKER
10 20 30
80 90 100 110 120 130
pF1KB6 IVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLA
40 50 60 70 80 90
140 150 160 170 180
pF1KB6 RLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
::::::::::::::::::::::::::::::::::::::::::::::: : :
XP_011 RLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLRCCHYRGRAWAGQ
100 110 120 130 140 150
XP_011 SRAGRDVGAEAPITRYL
160
>>NP_473454 (OMIM: 610645) calcium and integrin-binding (187 aa)
initn: 820 init1: 820 opt: 820 Z-score: 921.3 bits: 177.2 E(85289): 1.4e-44
Smith-Waterman score: 820; 61.5% identity (87.2% similar) in 187 aa overlap (1-187:1-187)
10 20 30 40 50 60
pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
::::::.::.:::. :::::::..:.:..: :. .:::.:::.:: : :.::. ::
NP_473 MGNKQTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKVPYELIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTD
.::::..:::..::. .:::::.:..:...:.:::::. : :::.::: :::::::::.:
NP_473 SMPELKDNPFRQRIAQVFSEDGDGHMTLDNFLDMFSVMSEMAPRDLKAYYAFKIYDFNND
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFL
..:: ::: :...::.. :. ::: :::.::..::: : ::.:.. ::..:: .:::::
NP_473 DYICAWDLEQTVTKLTRGGLSAEEVSLVCEKVLDEADGDHDGRLSLEDFQNMILRAPDFL
130 140 150 160 170 180
pF1KB6 STFHIRI
:::::::
NP_473 STFHIRI
>>NP_001258818 (OMIM: 605564,609439,614869) calcium and (138 aa)
initn: 804 init1: 804 opt: 804 Z-score: 905.3 bits: 173.8 E(85289): 1.1e-43
Smith-Waterman score: 804; 96.1% identity (98.4% similar) in 127 aa overlap (61-187:12-138)
40 50 60 70 80 90
pF1KB6 HSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVAAFSEDGEGNLTFND
:. . .::::::::::::::::::::::::
NP_001 MGNKQTIFTEEQLDNYQENPFKERIVAAFSEDGEGNLTFND
10 20 30 40
100 110 120 130 140 150
pF1KB6 FVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCD
50 60 70 80 90 100
160 170 180
pF1KB6 KVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
:::::::::::::::::::::::::::::::::::::
NP_001 KVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
110 120 130
>>NP_001287851 (OMIM: 610645) calcium and integrin-bindi (138 aa)
initn: 541 init1: 541 opt: 541 Z-score: 614.7 bits: 120.0 E(85289): 1.7e-27
Smith-Waterman score: 541; 59.8% identity (86.6% similar) in 127 aa overlap (61-187:12-138)
40 50 60 70 80 90
pF1KB6 HSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVAAFSEDGEGNLTFND
:. ..:::..::. .:::::.:..:...
NP_001 MGNKQTVFTHEQLEAYQDNPFRQRIAQVFSEDGDGHMTLDN
10 20 30 40
100 110 120 130 140 150
pF1KB6 FVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCD
:.:::::. : :::.::: :::::::::.:..:: ::: :...::.. :. ::: :::.
NP_001 FLDMFSVMSEMAPRDLKAYYAFKIYDFNNDDYICAWDLEQTVTKLTRGGLSAEEVSLVCE
50 60 70 80 90 100
160 170 180
pF1KB6 KVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
::..::: : ::.:.. ::..:: .::::::::::::
NP_001 KVLDEADGDHDGRLSLEDFQNMILRAPDFLSTFHIRI
110 120 130
>>NP_006375 (OMIM: 602293) calcium and integrin-binding (191 aa)
initn: 284 init1: 185 opt: 447 Z-score: 509.0 bits: 100.9 E(85289): 1.3e-21
Smith-Waterman score: 447; 37.9% identity (73.7% similar) in 190 aa overlap (1-185:1-189)
10 20 30 40 50 60
pF1KB6 MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLII
::.. . ...: : .::: ::..:..:: : :: :: :. . ..: ..::. :.
NP_006 MGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQE-QRSVESSLRAQVPFEQIL
10 20 30 40 50
70 80 90 100 110
pF1KB6 QMPELRENPFKERIVAAFSED-GEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNT
..:::. ::::::: .:: . .. .:.:.::.:..::. ..: ..:..:::.:.::.
NP_006 SLPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 DNFICKEDLELTLARLT----KSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAK
:. . .::: . :: ..:. :. . :...::.:.: :: .....:. .:..
NP_006 DGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR
120 130 140 150 160 170
180
pF1KB6 APDFLSTFHIRI
.::: :.:.:
NP_006 SPDFASSFKIVL
180 190
187 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:23:39 2016 done: Fri Nov 4 14:23:40 2016
Total Scan time: 5.280 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]