FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6826, 187 aa 1>>>pF1KB6826 187 - 187 aa - 187 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7362+/-0.000806; mu= 10.7431+/- 0.048 mean_var=65.1612+/-13.245, 0's: 0 Z-trim(106.4): 26 B-trim: 84 in 1/52 Lambda= 0.158884 statistics sampled from 8965 (8983) to 8965 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.276), width: 16 Scan time: 1.690 The best scores are: opt bits E(32554) CCDS6495.1 IFNB1 gene_id:3456|Hs108|chr9 ( 187) 1235 291.5 2e-79 CCDS34997.1 IFNE gene_id:338376|Hs108|chr9 ( 208) 380 95.6 2.2e-20 CCDS34996.1 IFNA16 gene_id:3449|Hs108|chr9 ( 189) 347 88.0 3.8e-18 CCDS6502.1 IFNA5 gene_id:3442|Hs108|chr9 ( 189) 346 87.8 4.4e-18 CCDS6501.1 IFNA14 gene_id:3448|Hs108|chr9 ( 189) 338 85.9 1.6e-17 CCDS6498.1 IFNA4 gene_id:3441|Hs108|chr9 ( 189) 335 85.2 2.5e-17 CCDS6496.1 IFNW1 gene_id:3467|Hs108|chr9 ( 195) 334 85.0 3.1e-17 CCDS6500.1 IFNA17 gene_id:3451|Hs108|chr9 ( 189) 331 84.3 4.8e-17 CCDS34995.1 IFNA7 gene_id:3444|Hs108|chr9 ( 189) 330 84.1 5.6e-17 CCDS6499.1 IFNA10 gene_id:3446|Hs108|chr9 ( 189) 325 82.9 1.2e-16 CCDS6506.1 IFNA2 gene_id:3440|Hs108|chr9 ( 188) 324 82.7 1.4e-16 CCDS6505.2 IFNA13 gene_id:3447|Hs108|chr9 ( 190) 312 80.0 9.8e-16 CCDS6497.1 IFNA21 gene_id:3452|Hs108|chr9 ( 189) 310 79.5 1.3e-15 CCDS6508.1 IFNA1 gene_id:3439|Hs108|chr9 ( 189) 310 79.5 1.3e-15 CCDS6504.1 IFNA6 gene_id:3443|Hs108|chr9 ( 189) 308 79.0 1.8e-15 CCDS6507.1 IFNA8 gene_id:3445|Hs108|chr9 ( 189) 291 75.1 2.7e-14 >>CCDS6495.1 IFNB1 gene_id:3456|Hs108|chr9 (187 aa) initn: 1235 init1: 1235 opt: 1235 Z-score: 1539.5 bits: 291.5 E(32554): 2e-79 Smith-Waterman score: 1235; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187) 10 20 30 40 50 60 pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 TVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR 130 140 150 160 170 180 pF1KB6 LTGYLRN ::::::: CCDS64 LTGYLRN >>CCDS34997.1 IFNE gene_id:338376|Hs108|chr9 (208 aa) initn: 370 init1: 320 opt: 380 Z-score: 479.6 bits: 95.6 E(32554): 2.2e-20 Smith-Waterman score: 380; 37.2% identity (68.3% similar) in 183 aa overlap (1-182:1-183) 10 20 30 40 50 pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNG-RLEYCLKDRMNF : : .. .:.: ::: .:.. .:. : ::. : . ::: .:. .. :: : :: CCDS34 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 DIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHL .:.. . ::.:: . ..::::.::..:: . : ::.:. .:..: ....:...: CCDS34 LLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 KTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFIN .... . :: . : :. :..: :. :: ::. ..:: :::.::.::: : ..:. CCDS34 EALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVF 130 140 150 160 170 180 180 pF1KB6 RLTGYLRN :: CCDS34 SLTEKLSKQGRPLNDMKQELTTEFRSPR 190 200 >>CCDS34996.1 IFNA16 gene_id:3449|Hs108|chr9 (189 aa) initn: 338 init1: 338 opt: 347 Z-score: 439.4 bits: 88.0 E(32554): 3.8e-18 Smith-Waterman score: 347; 37.2% identity (72.3% similar) in 148 aa overlap (41-186:40-186) 20 30 40 50 60 pF1KB6 LLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEY--CLKDRMNFDIPEEIKQL :: :. ::. . :::::..: .:.:. . CCDS34 AVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQM-GRISHFSCLKDRYDFGFPQEVFDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLE .:::: .: ...::.:. : .: .::..:.::..... ....:.: :.. . ... CCDS34 NQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLEACVTQEVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN :... . : : ...:. :: :: .:.:: ::: .::.::.:.: : . : :: CCDS34 VEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTNLQKGLRRK 130 140 150 160 170 180 CCDS34 D >>CCDS6502.1 IFNA5 gene_id:3442|Hs108|chr9 (189 aa) initn: 335 init1: 335 opt: 346 Z-score: 438.1 bits: 87.8 E(32554): 4.4e-18 Smith-Waterman score: 346; 33.9% identity (64.5% similar) in 183 aa overlap (6-186:8-186) 10 20 30 40 50 pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLE--YCLKDR :. ...: : : .:. . : . :: . .. :. ::. ::::: CCDS65 MALPFVLLMALVVLNCKSICSLGCD---LPQTHSLSNRRTLMIMAQM-GRISPFSCLKDR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 MNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQI .: .:.: . .:::: .: ...::.:. : .: .::. :.::..... ...:.:. CCDS65 HDFGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 NHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFY : :.. . ... :: .. : : ...:. :: :: :.:: ::: .::.::.:.: CCDS65 NDLEACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFS 120 130 140 150 160 170 180 pF1KB6 FINRLTGYLRN . : :: CCDS65 LSANLQERLRRKE 180 >>CCDS6501.1 IFNA14 gene_id:3448|Hs108|chr9 (189 aa) initn: 331 init1: 331 opt: 338 Z-score: 428.2 bits: 85.9 E(32554): 1.6e-17 Smith-Waterman score: 338; 32.4% identity (65.4% similar) in 182 aa overlap (6-186:8-186) 10 20 30 40 50 pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEY-CLKDRM .. ...: : :. .:. . :. . .: . :. :. . ::::: CCDS65 MALPFALMMALVVLSCKSSCSLGCN---LSQTHSLNNRRTLMLMAQMRRISPFSCLKDRH 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQIN .:..:.: . .:::: .: ...::.:. : .: .::..:.::..:.. ....:.: CCDS65 DFEFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 HLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYF :.. . ... :. . : : .:.:. :: :: :.:: ::: .::.::.:.. : CCDS65 DLEACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSF 120 130 140 150 160 170 180 pF1KB6 INRLTGYLRN . : :: CCDS65 STNLQKRLRRKD 180 >>CCDS6498.1 IFNA4 gene_id:3441|Hs108|chr9 (189 aa) initn: 326 init1: 326 opt: 335 Z-score: 424.5 bits: 85.2 E(32554): 2.5e-17 Smith-Waterman score: 335; 37.2% identity (70.3% similar) in 148 aa overlap (41-186:40-186) 20 30 40 50 60 pF1KB6 LLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEY--CLKDRMNFDIPEEIKQL :: :. ::. . ::::: .: .::: . CCDS64 AVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQM-GRISHFSCLKDRHDFGFPEEEFDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLE .:::: .: ...::.:. : .: ..::..:.....:.. ...:.:.: :.. . ... CCDS64 HQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN :. . : : ...:. :: :: :.:: ::: .::.::.:.. : . : :: CCDS64 VEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRK 130 140 150 160 170 180 CCDS64 D >>CCDS6496.1 IFNW1 gene_id:3467|Hs108|chr9 (195 aa) initn: 351 init1: 328 opt: 334 Z-score: 423.0 bits: 85.0 E(32554): 3.1e-17 Smith-Waterman score: 334; 38.0% identity (73.7% similar) in 137 aa overlap (52-187:52-187) 30 40 50 60 70 80 pF1KB6 MSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIY ::::: .: .:.:. . .:.:: . ... CCDS64 LGCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFRFPQEMVKGSQLQKAHVMSVLH 30 40 50 60 70 80 90 100 110 120 130 140 pF1KB6 EMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMS-S ::::.::..:. . ::..:: :....: .....:..::.: : . . : . : . : . CCDS64 EMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHLETCLLQVV-GEGESAGAISSPA 90 100 110 120 130 140 150 160 170 180 pF1KB6 LHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN : :.::. : ::: :.:: ::: .::.::...... . . ::. CCDS64 LTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTNMQERLRSKDRDLGSS 150 160 170 180 190 >>CCDS6500.1 IFNA17 gene_id:3451|Hs108|chr9 (189 aa) initn: 326 init1: 326 opt: 331 Z-score: 419.5 bits: 84.3 E(32554): 4.8e-17 Smith-Waterman score: 331; 36.5% identity (70.3% similar) in 148 aa overlap (41-186:40-186) 20 30 40 50 60 pF1KB6 LLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLE--YCLKDRMNFDIPEEIKQL :: :. ::. ::::: .: .:.: . CCDS65 AVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQM-GRISPFSCLKDRHDFGLPQEEFDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLE .:::: .: ...::.:. : .: ..::..:.....:.. ...:.:.:.:.. . ... CCDS65 NQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACVIQEVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN :. . : : ...:. :: :: :.:: ::: .::.::.:.. : . : :: CCDS65 MEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKILRRK 130 140 150 160 170 180 CCDS65 D >>CCDS34995.1 IFNA7 gene_id:3444|Hs108|chr9 (189 aa) initn: 319 init1: 319 opt: 330 Z-score: 418.3 bits: 84.1 E(32554): 5.6e-17 Smith-Waterman score: 330; 35.3% identity (63.7% similar) in 190 aa overlap (6-186:7-186) 10 20 30 40 50 pF1KB6 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLE--YCLKDRM ::...:.: ... :.. .: . : . :: :. ::. ::::: CCDS34 MARSFSLLMVVLVLSYKSIC-SLGCDL-PQTHSLRNRRALILLAQM-GRISPFSCLKDRH 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQIN .: .::: . .:::: .: ...::.:. : .: ..::..:.....:.. ...:.:.: CCDS34 EFRFPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 HLKT-------VLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVE :.. : : : .::: : ...:. :: :: :.:: ::: .::.: CCDS34 DLEACVIQEVGVEETPLMNEDFI-------LAVRKYFQRITLYLMEKKYSPCAWEVVRAE 120 130 140 150 160 170 180 pF1KB6 ILRNFYFINRLTGYLRN :.:.: : . : :: CCDS34 IMRSFSFSTNLKKGLRRKD 180 >>CCDS6499.1 IFNA10 gene_id:3446|Hs108|chr9 (189 aa) initn: 320 init1: 320 opt: 325 Z-score: 412.1 bits: 82.9 E(32554): 1.2e-16 Smith-Waterman score: 325; 36.5% identity (69.6% similar) in 148 aa overlap (41-186:40-186) 20 30 40 50 60 pF1KB6 LLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLE--YCLKDRMNFDIPEEIKQL :: :. ::. ::::: .: ::.: . CCDS64 AVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQM-GRISPFSCLKDRHDFRIPQEEFDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLE .:::: .: ...::.:. : .: ..::..:.....:.. ...:.:.: :.. . ... CCDS64 NQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN :. . : : ...:. :: :: ..:: ::: .::.::.:.. : . : :: CCDS64 VEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRK 130 140 150 160 170 180 CCDS64 D 187 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:27:19 2016 done: Sat Nov 5 20:27:19 2016 Total Scan time: 1.690 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]