FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6829, 166 aa 1>>>pF1KB6829 166 - 166 aa - 166 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3434+/-0.000719; mu= 11.6890+/- 0.043 mean_var=57.2458+/-11.482, 0's: 0 Z-trim(108.9): 120 B-trim: 304 in 1/50 Lambda= 0.169513 statistics sampled from 10378 (10503) to 10378 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.323), width: 16 Scan time: 1.660 The best scores are: opt bits E(32554) CCDS1964.1 REG1A gene_id:5967|Hs108|chr2 ( 166) 1165 292.6 7.5e-80 CCDS1963.1 REG1B gene_id:5968|Hs108|chr2 ( 166) 1006 253.7 3.8e-68 CCDS1965.1 REG3A gene_id:5068|Hs108|chr2 ( 175) 588 151.5 2.4e-37 CCDS1962.1 REG3G gene_id:130120|Hs108|chr2 ( 175) 582 150.0 6.6e-37 CCDS906.1 REG4 gene_id:83998|Hs108|chr1 ( 158) 317 85.2 1.9e-17 CCDS56087.1 CLEC17A gene_id:388512|Hs108|chr19 ( 378) 268 73.3 1.7e-13 CCDS32782.1 COLEC12 gene_id:81035|Hs108|chr18 ( 742) 264 72.4 6.2e-13 CCDS53971.1 ACAN gene_id:176|Hs108|chr15 (2431) 264 72.6 1.8e-12 CCDS53970.1 ACAN gene_id:176|Hs108|chr15 (2530) 264 72.6 1.9e-12 CCDS12184.1 FCER2 gene_id:2208|Hs108|chr19 ( 321) 252 69.4 2.2e-12 CCDS11634.1 MRC2 gene_id:9902|Hs108|chr17 (1479) 258 71.1 3.2e-12 CCDS12397.1 NCAN gene_id:1463|Hs108|chr19 (1321) 253 69.8 6.8e-12 CCDS31739.1 CLEC6A gene_id:93978|Hs108|chr12 ( 209) 230 64.0 6.3e-11 CCDS7123.2 MRC1 gene_id:4360|Hs108|chr10 (1456) 239 66.4 8e-11 CCDS56017.1 ASGR1 gene_id:432|Hs108|chr17 ( 252) 229 63.7 8.9e-11 CCDS47242.1 VCAN gene_id:1462|Hs108|chr5 ( 655) 234 65.1 9e-11 CCDS11088.1 ASGR2 gene_id:433|Hs108|chr17 ( 287) 229 63.8 1e-10 >>CCDS1964.1 REG1A gene_id:5967|Hs108|chr2 (166 aa) initn: 1165 init1: 1165 opt: 1165 Z-score: 1547.0 bits: 292.6 E(32554): 7.5e-80 Smith-Waterman score: 1165; 100.0% identity (100.0% similar) in 166 aa overlap (1-166:1-166) 10 20 30 40 50 60 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 DLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVS 70 80 90 100 110 120 130 140 150 160 pF1KB6 YKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN :::::::::::::::::::::::::::::::::::::::::::::: CCDS19 YKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN 130 140 150 160 >>CCDS1963.1 REG1B gene_id:5968|Hs108|chr2 (166 aa) initn: 1006 init1: 1006 opt: 1006 Z-score: 1336.9 bits: 253.7 E(32554): 3.8e-68 Smith-Waterman score: 1006; 86.7% identity (92.8% similar) in 166 aa overlap (1-166:1-166) 10 20 30 40 50 60 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDA ::::.:.::::: ::::: :::::.:::::. ::::::::::::::::::::: :::::: CCDS19 MAQTNSFFMLISSLMFLSLSQGQESQTELPNPRISCPEGTNAYRSYCYYFNEDPETWVDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVS :::::::::::::::::::::::::::::::.::: :::::::::::::::::::::::: CCDS19 DLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKKNRRWHWSSGSLVS 70 80 90 100 110 120 130 140 150 160 pF1KB6 YKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN :::: :.:::.: :::.:::: .::.:::: :: :::::::::: CCDS19 YKSWDTGSPSSANAGYCASLTSCSGFKKWKDESCEKKFSFVCKFKN 130 140 150 160 >>CCDS1965.1 REG3A gene_id:5068|Hs108|chr2 (175 aa) initn: 578 init1: 417 opt: 588 Z-score: 784.0 bits: 151.5 E(32554): 2.4e-37 Smith-Waterman score: 588; 50.0% identity (75.6% similar) in 172 aa overlap (1-166:5-175) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET :: : .::.::::.::: ::.: : :::.::: ::.:..:: :.:: . . .. CCDS19 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W :.:::: ::. ::::::::. :::.::.::.: :.. :::::::: .. . : CCDS19 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 HWSSGSLVSYKSWGIGAPSSVN-PGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN .:::.....: .: ::... ::.:.::. ::.: .::: :. .. .:::: . CCDS19 EWSSSDVMNYFAWE-RNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD 130 140 150 160 170 >>CCDS1962.1 REG3G gene_id:130120|Hs108|chr2 (175 aa) initn: 574 init1: 384 opt: 582 Z-score: 776.1 bits: 150.0 E(32554): 6.6e-37 Smith-Waterman score: 582; 48.5% identity (74.3% similar) in 171 aa overlap (1-166:5-175) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET :: : .::.:::..: : ::.:.: :::. :::::.:..:: : :: . . .. CCDS19 MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W :.:::: ::. ::.:::::. :::.::.::.. ... .::::::: .. . : CCDS19 WMDADLACQKRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGLHDPTQGSEPDGDGW 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 HWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN .::: ....: .: . . .:::.: ::. :::: :::: :. :. .:::::. CCDS19 EWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD 130 140 150 160 170 >>CCDS906.1 REG4 gene_id:83998|Hs108|chr1 (158 aa) initn: 238 init1: 218 opt: 317 Z-score: 426.6 bits: 85.2 E(32554): 1.9e-17 Smith-Waterman score: 317; 36.0% identity (67.6% similar) in 136 aa overlap (33-165:27-157) 10 20 30 40 50 60 pF1KB6 QTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCY-YFNEDRETWVDAD : :: : ..: :: :: . :. : ::. CCDS90 MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRN-WSDAE 10 20 30 40 50 70 80 90 100 110 pF1KB6 LYCQNMNSG-NLVSVLTQAEGAFVASLIKESGTDDFN-VWIGLHDPKKNRRWHWSSGSLV : ::....: .:.:.:. :.. .: : :: . . .:::::::.: ..:.: .:.. CCDS90 LECQSYGNGAHLASILSLKEASTIAEYI--SGYQRSQPIWIGLHDPQKRQQWQWIDGAMY 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 SYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN :.::. : . : .:. ..:...: :.. :. . :.::.. CCDS90 LYRSWS-GKSMGGNK-HCAEMSSNNNFLTWSSNECNKRQHFLCKYRP 120 130 140 150 >>CCDS56087.1 CLEC17A gene_id:388512|Hs108|chr19 (378 aa) initn: 128 init1: 128 opt: 268 Z-score: 355.7 bits: 73.3 E(32554): 1.7e-13 Smith-Waterman score: 268; 31.6% identity (61.7% similar) in 133 aa overlap (33-165:251-375) 10 20 30 40 50 60 pF1KB6 QTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADL ::.:::: ... ::::. . ..: .: . CCDS56 GLAGLKHDIARVRADTNQSLVELWGLLDCRRITCPEGWLPFEGKCYYFSPSTKSWDEARM 230 240 250 260 270 280 70 80 90 100 110 120 pF1KB6 YCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYK .::. : ..:: . . :: ::: : :. :.::.: .. :.: .:: :. . CCDS56 FCQE-NYSHLVIINSFAEHNFVA---KAHGSPRV-YWLGLNDRAQEGDWRWLDGSPVTLS 290 300 310 320 330 130 140 150 160 pF1KB6 SWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN : :.... :...... : :.:. : ..:. : CCDS56 FWEPEEPNNIHDEDCATMNKG-G--TWNDLSCYKTTYWICERKCSC 340 350 360 370 >>CCDS32782.1 COLEC12 gene_id:81035|Hs108|chr18 (742 aa) initn: 241 init1: 117 opt: 264 Z-score: 345.6 bits: 72.4 E(32554): 6.2e-13 Smith-Waterman score: 264; 30.8% identity (61.0% similar) in 146 aa overlap (23-163:595-731) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNE :. : :. .:: . . . ::::. CCDS32 PGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDN-GCPPHWKNFTDKCYYFSV 570 580 590 600 610 620 60 70 80 90 100 110 pF1KB6 DRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWH ..: . :: :.:.. .:..:: . :. : . ::.. . . :::: : ... .:. CCDS32 EKEIFEDAKLFCED-KSSHLVFINTREEQQW----IKKQMVGRESHWIGLTDSERENEWK 630 640 650 660 670 120 130 140 150 160 pF1KB6 WSSGSLVSYKSWGIGAPSSVNPGY-----CVSLTSSTGFQKWKDVPCEDKFSFVCKFKN : .:. .::.: : :.. . :. :..: . : .:.: ::: .:.:. CCDS32 WLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYA-G--QWNDFQCEDVNNFICEKDRE 680 690 700 710 720 730 CCDS32 TVLSSAL 740 >>CCDS53971.1 ACAN gene_id:176|Hs108|chr15 (2431 aa) initn: 225 init1: 118 opt: 264 Z-score: 337.2 bits: 72.6 E(32554): 1.8e-12 Smith-Waterman score: 264; 35.1% identity (64.1% similar) in 131 aa overlap (36-163:2282-2403) 10 20 30 40 50 60 pF1KB6 SYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQ : :: : :...:: ::::::::. :. CCDS53 ETATSPTDASIPASPEWKRESESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCR 2260 2270 2280 2290 2300 2310 70 80 90 100 110 120 pF1KB6 NMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWG ...: .: :..: : :: .....:.. ::::.: . ..::.: .....: CCDS53 EQQS-HLSSIVTPEEQEFV-----NNNAQDYQ-WIGLNDRTIEGDFRWSDGHPMQFENWR 2320 2330 2340 2350 2360 130 140 150 160 pF1KB6 IGAPSSV-NPGY-CVSLT-SSTGFQKWKDVPCEDKFSFVCKFKN . :.. : :: . : .:.::::. .. :.:: CCDS53 PNQPDNFFAAGEDCVVMIWHEKG--EWNDVPCNYHLPFTCKKGTATTYKRRLQKRSSRHP 2370 2380 2390 2400 2410 2420 CCDS53 RRSRPSTAH 2430 >>CCDS53970.1 ACAN gene_id:176|Hs108|chr15 (2530 aa) initn: 225 init1: 118 opt: 264 Z-score: 337.0 bits: 72.6 E(32554): 1.9e-12 Smith-Waterman score: 264; 35.1% identity (64.1% similar) in 131 aa overlap (36-163:2320-2441) 10 20 30 40 50 60 pF1KB6 SYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQ : :: : :...:: ::::::::. :. CCDS53 AGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCR 2290 2300 2310 2320 2330 2340 70 80 90 100 110 120 pF1KB6 NMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWG ...: .: :..: : :: .....:.. ::::.: . ..::.: .....: CCDS53 EQQS-HLSSIVTPEEQEFV-----NNNAQDYQ-WIGLNDRTIEGDFRWSDGHPMQFENWR 2350 2360 2370 2380 2390 2400 130 140 150 160 pF1KB6 IGAPSSV-NPGY-CVSLT-SSTGFQKWKDVPCEDKFSFVCKFKN . :.. : :: . : .:.::::. .. :.:: CCDS53 PNQPDNFFAAGEDCVVMIWHEKG--EWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFG 2410 2420 2430 2440 2450 2460 CCDS53 QKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQKRSSRH 2470 2480 2490 2500 2510 2520 >>CCDS12184.1 FCER2 gene_id:2208|Hs108|chr19 (321 aa) initn: 191 init1: 99 opt: 252 Z-score: 335.7 bits: 69.4 E(32554): 2.2e-12 Smith-Waterman score: 252; 32.3% identity (63.1% similar) in 130 aa overlap (35-162:162-282) 10 20 30 40 50 60 pF1KB6 SSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYC .::: .. ::::.. . :: : : CCDS12 NEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYAC 140 150 160 170 180 190 70 80 90 100 110 120 pF1KB6 QNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSW ..:. :.:::. . : :... ...:. ::::.. . .. : .:: :.:..: CCDS12 DDME-GQLVSIHSPEEQDFLTKHASHTGS-----WIGLRNLDLKGEFIWVDGSHVDYSNW 200 210 220 230 240 130 140 150 160 pF1KB6 GIGAPSSVNPGY-CVSLTSSTGFQKWKDVPCEDKF-SFVCKFKN . : :.: . : :: . .: .:.:. :. :. ..:: CCDS12 APGEPTSRSQGEDCVMMRGS---GRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGP 250 260 270 280 290 300 CCDS12 DSRPDPDGRLPTPSAPLHS 310 320 166 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:06:04 2016 done: Sat Nov 5 14:06:04 2016 Total Scan time: 1.660 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]