FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6829, 166 aa 1>>>pF1KB6829 166 - 166 aa - 166 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9911+/-0.000329; mu= 13.9382+/- 0.021 mean_var=59.0920+/-11.607, 0's: 0 Z-trim(115.7): 271 B-trim: 0 in 0/50 Lambda= 0.166844 statistics sampled from 26087 (26372) to 26087 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.309), width: 16 Scan time: 4.540 The best scores are: opt bits E(85289) NP_002900 (OMIM: 167770) lithostathine-1-alpha pre ( 166) 1165 288.2 4.1e-78 NP_006498 (OMIM: 167771) lithostathine-1-beta prec ( 166) 1006 249.9 1.4e-66 NP_002571 (OMIM: 167805) regenerating islet-derive ( 175) 588 149.3 2.8e-36 NP_620355 (OMIM: 167805) regenerating islet-derive ( 175) 588 149.3 2.8e-36 NP_620354 (OMIM: 167805) regenerating islet-derive ( 175) 588 149.3 2.8e-36 NP_001008388 (OMIM: 609933) regenerating islet-der ( 175) 582 147.9 7.5e-36 NP_940850 (OMIM: 609933) regenerating islet-derive ( 175) 582 147.9 7.5e-36 XP_005264192 (OMIM: 609933) PREDICTED: regeneratin ( 175) 582 147.9 7.5e-36 NP_001152824 (OMIM: 609846) regenerating islet-der ( 158) 317 84.1 1.1e-16 NP_114433 (OMIM: 609846) regenerating islet-derive ( 158) 317 84.1 1.1e-16 XP_016882280 (OMIM: 616838) PREDICTED: C-type lect ( 243) 268 72.4 5.6e-13 XP_016882279 (OMIM: 616838) PREDICTED: C-type lect ( 293) 268 72.4 6.5e-13 XP_016882274 (OMIM: 616838) PREDICTED: C-type lect ( 310) 268 72.4 6.9e-13 XP_016882278 (OMIM: 616838) PREDICTED: C-type lect ( 310) 268 72.4 6.9e-13 XP_016882275 (OMIM: 616838) PREDICTED: C-type lect ( 310) 268 72.4 6.9e-13 XP_016882277 (OMIM: 616838) PREDICTED: C-type lect ( 310) 268 72.4 6.9e-13 XP_016882276 (OMIM: 616838) PREDICTED: C-type lect ( 310) 268 72.4 6.9e-13 NP_001191047 (OMIM: 616838) C-type lectin domain f ( 378) 268 72.5 8.1e-13 XP_011524043 (OMIM: 607621) PREDICTED: collectin-1 ( 725) 264 71.7 2.7e-12 NP_569057 (OMIM: 607621) collectin-12 [Homo sapien ( 742) 264 71.7 2.8e-12 NP_001126 (OMIM: 155760,165800,608361,612813) aggr (2431) 264 72.0 7.4e-12 XP_011519616 (OMIM: 155760,165800,608361,612813) P (2492) 264 72.0 7.6e-12 XP_016877476 (OMIM: 155760,165800,608361,612813) P (2515) 264 72.0 7.6e-12 XP_011519615 (OMIM: 155760,165800,608361,612813) P (2530) 264 72.0 7.7e-12 NP_037359 (OMIM: 155760,165800,608361,612813) aggr (2530) 264 72.0 7.7e-12 XP_016877474 (OMIM: 155760,165800,608361,612813) P (2553) 264 72.0 7.7e-12 XP_016877475 (OMIM: 155760,165800,608361,612813) P (2553) 264 72.0 7.7e-12 XP_006720482 (OMIM: 155760,165800,608361,612813) P (2568) 264 72.0 7.8e-12 NP_001193948 (OMIM: 151445) low affinity immunoglo ( 320) 252 68.6 1e-11 NP_001993 (OMIM: 151445) low affinity immunoglobul ( 321) 252 68.6 1e-11 NP_001207429 (OMIM: 151445) low affinity immunoglo ( 321) 252 68.6 1e-11 XP_005272519 (OMIM: 151445) PREDICTED: low affinit ( 321) 252 68.6 1e-11 XP_011523845 (OMIM: 612264) PREDICTED: C-type mann (1156) 258 70.3 1.1e-11 NP_006030 (OMIM: 612264) C-type mannose receptor 2 (1479) 258 70.4 1.3e-11 NP_004377 (OMIM: 600826) neurocan core protein pre (1321) 253 69.2 2.8e-11 NP_001304928 (OMIM: 613579) C-type lectin domain f ( 179) 230 63.2 2.5e-10 NP_001007034 (OMIM: 613579) C-type lectin domain f ( 209) 230 63.2 2.8e-10 NP_002429 (OMIM: 153618) macrophage mannose recept (1456) 239 65.8 3.1e-10 NP_001119808 (OMIM: 118661,143200) versican core p ( 655) 234 64.4 3.7e-10 XP_006721587 (OMIM: 108361) PREDICTED: asialoglyco ( 248) 229 63.0 3.8e-10 NP_001184145 (OMIM: 108360) asialoglycoprotein rec ( 252) 229 63.0 3.9e-10 NP_550435 (OMIM: 108361) asialoglycoprotein recept ( 287) 229 63.0 4.3e-10 XP_006721589 (OMIM: 108361) PREDICTED: asialoglyco ( 287) 229 63.0 4.3e-10 XP_005256705 (OMIM: 108361) PREDICTED: asialoglyco ( 287) 229 63.0 4.3e-10 XP_011522163 (OMIM: 108360) PREDICTED: asialoglyco ( 291) 229 63.0 4.4e-10 NP_001662 (OMIM: 108360) asialoglycoprotein recept ( 291) 229 63.0 4.4e-10 NP_550436 (OMIM: 108361) asialoglycoprotein recept ( 292) 229 63.0 4.4e-10 XP_016880140 (OMIM: 108361) PREDICTED: asialoglyco ( 292) 229 63.0 4.4e-10 XP_011522167 (OMIM: 108361) PREDICTED: asialoglyco ( 299) 229 63.0 4.5e-10 XP_011522165 (OMIM: 108361) PREDICTED: asialoglyco ( 299) 229 63.0 4.5e-10 >>NP_002900 (OMIM: 167770) lithostathine-1-alpha precurs (166 aa) initn: 1165 init1: 1165 opt: 1165 Z-score: 1523.3 bits: 288.2 E(85289): 4.1e-78 Smith-Waterman score: 1165; 100.0% identity (100.0% similar) in 166 aa overlap (1-166:1-166) 10 20 30 40 50 60 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVS 70 80 90 100 110 120 130 140 150 160 pF1KB6 YKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN :::::::::::::::::::::::::::::::::::::::::::::: NP_002 YKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN 130 140 150 160 >>NP_006498 (OMIM: 167771) lithostathine-1-beta precurso (166 aa) initn: 1006 init1: 1006 opt: 1006 Z-score: 1316.5 bits: 249.9 E(85289): 1.4e-66 Smith-Waterman score: 1006; 86.7% identity (92.8% similar) in 166 aa overlap (1-166:1-166) 10 20 30 40 50 60 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDA ::::.:.::::: ::::: :::::.:::::. ::::::::::::::::::::: :::::: NP_006 MAQTNSFFMLISSLMFLSLSQGQESQTELPNPRISCPEGTNAYRSYCYYFNEDPETWVDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVS :::::::::::::::::::::::::::::::.::: :::::::::::::::::::::::: NP_006 DLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKKNRRWHWSSGSLVS 70 80 90 100 110 120 130 140 150 160 pF1KB6 YKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN :::: :.:::.: :::.:::: .::.:::: :: :::::::::: NP_006 YKSWDTGSPSSANAGYCASLTSCSGFKKWKDESCEKKFSFVCKFKN 130 140 150 160 >>NP_002571 (OMIM: 167805) regenerating islet-derived pr (175 aa) initn: 578 init1: 417 opt: 588 Z-score: 772.4 bits: 149.3 E(85289): 2.8e-36 Smith-Waterman score: 588; 50.0% identity (75.6% similar) in 172 aa overlap (1-166:5-175) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET :: : .::.::::.::: ::.: : :::.::: ::.:..:: :.:: . . .. NP_002 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W :.:::: ::. ::::::::. :::.::.::.: :.. :::::::: .. . : NP_002 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 HWSSGSLVSYKSWGIGAPSSVN-PGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN .:::.....: .: ::... ::.:.::. ::.: .::: :. .. .:::: . NP_002 EWSSSDVMNYFAWE-RNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD 130 140 150 160 170 >>NP_620355 (OMIM: 167805) regenerating islet-derived pr (175 aa) initn: 578 init1: 417 opt: 588 Z-score: 772.4 bits: 149.3 E(85289): 2.8e-36 Smith-Waterman score: 588; 50.0% identity (75.6% similar) in 172 aa overlap (1-166:5-175) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET :: : .::.::::.::: ::.: : :::.::: ::.:..:: :.:: . . .. NP_620 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W :.:::: ::. ::::::::. :::.::.::.: :.. :::::::: .. . : NP_620 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 HWSSGSLVSYKSWGIGAPSSVN-PGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN .:::.....: .: ::... ::.:.::. ::.: .::: :. .. .:::: . NP_620 EWSSSDVMNYFAWE-RNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD 130 140 150 160 170 >>NP_620354 (OMIM: 167805) regenerating islet-derived pr (175 aa) initn: 578 init1: 417 opt: 588 Z-score: 772.4 bits: 149.3 E(85289): 2.8e-36 Smith-Waterman score: 588; 50.0% identity (75.6% similar) in 172 aa overlap (1-166:5-175) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET :: : .::.::::.::: ::.: : :::.::: ::.:..:: :.:: . . .. NP_620 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W :.:::: ::. ::::::::. :::.::.::.: :.. :::::::: .. . : NP_620 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 HWSSGSLVSYKSWGIGAPSSVN-PGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN .:::.....: .: ::... ::.:.::. ::.: .::: :. .. .:::: . NP_620 EWSSSDVMNYFAWE-RNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD 130 140 150 160 170 >>NP_001008388 (OMIM: 609933) regenerating islet-derived (175 aa) initn: 574 init1: 384 opt: 582 Z-score: 764.6 bits: 147.9 E(85289): 7.5e-36 Smith-Waterman score: 582; 48.5% identity (74.3% similar) in 171 aa overlap (1-166:5-175) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET :: : .::.:::..: : ::.:.: :::. :::::.:..:: : :: . . .. NP_001 MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W :.:::: ::. ::.:::::. :::.::.::.. ... .::::::: .. . : NP_001 WMDADLACQKRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGLHDPTQGSEPDGDGW 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 HWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN .::: ....: .: . . .:::.: ::. :::: :::: :. :. .:::::. NP_001 EWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD 130 140 150 160 170 >>NP_940850 (OMIM: 609933) regenerating islet-derived pr (175 aa) initn: 574 init1: 384 opt: 582 Z-score: 764.6 bits: 147.9 E(85289): 7.5e-36 Smith-Waterman score: 582; 48.5% identity (74.3% similar) in 171 aa overlap (1-166:5-175) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET :: : .::.:::..: : ::.:.: :::. :::::.:..:: : :: . . .. NP_940 MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W :.:::: ::. ::.:::::. :::.::.::.. ... .::::::: .. . : NP_940 WMDADLACQKRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGLHDPTQGSEPDGDGW 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 HWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN .::: ....: .: . . .:::.: ::. :::: :::: :. :. .:::::. NP_940 EWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD 130 140 150 160 170 >>XP_005264192 (OMIM: 609933) PREDICTED: regenerating is (175 aa) initn: 574 init1: 384 opt: 582 Z-score: 764.6 bits: 147.9 E(85289): 7.5e-36 Smith-Waterman score: 582; 48.5% identity (74.3% similar) in 171 aa overlap (1-166:5-175) 10 20 30 40 50 pF1KB6 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET :: : .::.:::..: : ::.:.: :::. :::::.:..:: : :: . . .. XP_005 MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W :.:::: ::. ::.:::::. :::.::.::.. ... .::::::: .. . : XP_005 WMDADLACQKRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGLHDPTQGSEPDGDGW 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 HWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN .::: ....: .: . . .:::.: ::. :::: :::: :. :. .:::::. XP_005 EWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD 130 140 150 160 170 >>NP_001152824 (OMIM: 609846) regenerating islet-derived (158 aa) initn: 238 init1: 218 opt: 317 Z-score: 420.5 bits: 84.1 E(85289): 1.1e-16 Smith-Waterman score: 317; 36.0% identity (67.6% similar) in 136 aa overlap (33-165:27-157) 10 20 30 40 50 60 pF1KB6 QTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCY-YFNEDRETWVDAD : :: : ..: :: :: . :. : ::. NP_001 MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRN-WSDAE 10 20 30 40 50 70 80 90 100 110 pF1KB6 LYCQNMNSG-NLVSVLTQAEGAFVASLIKESGTDDFN-VWIGLHDPKKNRRWHWSSGSLV : ::....: .:.:.:. :.. .: : :: . . .:::::::.: ..:.: .:.. NP_001 LECQSYGNGAHLASILSLKEASTIAEYI--SGYQRSQPIWIGLHDPQKRQQWQWIDGAMY 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 SYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN :.::. : . : .:. ..:...: :.. :. . :.::.. NP_001 LYRSWS-GKSMGGNK-HCAEMSSNNNFLTWSSNECNKRQHFLCKYRP 120 130 140 150 >>NP_114433 (OMIM: 609846) regenerating islet-derived pr (158 aa) initn: 238 init1: 218 opt: 317 Z-score: 420.5 bits: 84.1 E(85289): 1.1e-16 Smith-Waterman score: 317; 36.0% identity (67.6% similar) in 136 aa overlap (33-165:27-157) 10 20 30 40 50 60 pF1KB6 QTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCY-YFNEDRETWVDAD : :: : ..: :: :: . :. : ::. NP_114 MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRN-WSDAE 10 20 30 40 50 70 80 90 100 110 pF1KB6 LYCQNMNSG-NLVSVLTQAEGAFVASLIKESGTDDFN-VWIGLHDPKKNRRWHWSSGSLV : ::....: .:.:.:. :.. .: : :: . . .:::::::.: ..:.: .:.. NP_114 LECQSYGNGAHLASILSLKEASTIAEYI--SGYQRSQPIWIGLHDPQKRQQWQWIDGAMY 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 SYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN :.::. : . : .:. ..:...: :.. :. . :.::.. NP_114 LYRSWS-GKSMGGNK-HCAEMSSNNNFLTWSSNECNKRQHFLCKYRP 120 130 140 150 166 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:06:05 2016 done: Sat Nov 5 14:06:06 2016 Total Scan time: 4.540 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]