FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6833, 169 aa 1>>>pF1KB6833 169 - 169 aa - 169 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8386+/-0.00066; mu= 14.3871+/- 0.040 mean_var=54.0415+/-10.655, 0's: 0 Z-trim(109.5): 19 B-trim: 55 in 1/49 Lambda= 0.174466 statistics sampled from 10902 (10919) to 10902 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.335), width: 16 Scan time: 1.930 The best scores are: opt bits E(32554) CCDS10443.1 NME3 gene_id:4832|Hs108|chr16 ( 169) 1138 293.8 3.4e-80 CCDS11579.1 NME1 gene_id:4830|Hs108|chr17 ( 152) 726 190.1 5.1e-49 CCDS11578.1 NME1 gene_id:4830|Hs108|chr17 ( 177) 726 190.1 5.8e-49 CCDS11580.1 NME2 gene_id:4831|Hs108|chr17 ( 152) 711 186.3 7e-48 CCDS32682.1 NME2 gene_id:654364|Hs108|chr17 ( 267) 711 186.4 1.1e-47 CCDS10408.1 NME4 gene_id:4833|Hs108|chr16 ( 187) 652 171.5 2.5e-43 CCDS66886.1 NME4 gene_id:4833|Hs108|chr16 ( 117) 479 127.8 2.1e-30 CCDS74107.1 NME2 gene_id:4831|Hs108|chr17 ( 82) 356 96.8 3.3e-21 CCDS73797.1 NME4 gene_id:4833|Hs108|chr16 ( 153) 312 85.9 1.2e-17 CCDS77734.1 NME6 gene_id:10201|Hs108|chr3 ( 186) 251 70.5 6e-13 CCDS2763.1 NME6 gene_id:10201|Hs108|chr3 ( 194) 251 70.5 6.2e-13 CCDS44274.1 NME7 gene_id:29922|Hs108|chr1 ( 340) 250 70.4 1.2e-12 CCDS1277.1 NME7 gene_id:29922|Hs108|chr1 ( 376) 250 70.4 1.3e-12 >>CCDS10443.1 NME3 gene_id:4832|Hs108|chr16 (169 aa) initn: 1138 init1: 1138 opt: 1138 Z-score: 1553.2 bits: 293.8 E(32554): 3.4e-80 Smith-Waterman score: 1138; 100.0% identity (100.0% similar) in 169 aa overlap (1-169:1-169) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT 70 80 90 100 110 120 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE 130 140 150 160 >>CCDS11579.1 NME1 gene_id:4830|Hs108|chr17 (152 aa) initn: 726 init1: 726 opt: 726 Z-score: 993.5 bits: 190.1 E(32554): 5.1e-49 Smith-Waterman score: 726; 67.6% identity (93.2% similar) in 148 aa overlap (22-169:5-152) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.::.::..:: CCDS11 MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQA 10 20 30 40 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT ::.::.:::..:..:::.. ::::: :::::::::.::.::.:.:...: :::::. ::: CCDS11 SEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGT 50 60 70 80 90 100 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::.::.:.::::::::::..::.:::. .::. . . : .:.:: CCDS11 IRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 110 120 130 140 150 >>CCDS11578.1 NME1 gene_id:4830|Hs108|chr17 (177 aa) initn: 726 init1: 726 opt: 726 Z-score: 992.5 bits: 190.1 E(32554): 5.8e-49 Smith-Waterman score: 726; 67.6% identity (93.2% similar) in 148 aa overlap (22-169:30-177) 10 20 30 40 50 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKL ::::.:.::::::: :::::..:::.:::.: CCDS11 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 VALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATN :.::..::::.::.:::..:..:::.. ::::: :::::::::.::.::.:.:...: :: CCDS11 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 PADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::. ::::::::::.::.:.::::::::::..::.:::. .::. . . : .:.:: CCDS11 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 130 140 150 160 170 >>CCDS11580.1 NME2 gene_id:4831|Hs108|chr17 (152 aa) initn: 711 init1: 711 opt: 711 Z-score: 973.1 bits: 186.3 E(32554): 7e-48 Smith-Waterman score: 711; 65.5% identity (91.2% similar) in 148 aa overlap (22-169:5-152) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.:::.:...: CCDS11 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRA 10 20 30 40 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT ::: :..:: .:..:::. ::::: :::::::::.::.::.:.:...: :::::. ::: CCDS11 SEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGT 50 60 70 80 90 100 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::.::.:.:::::::.::..::.:::. .::. ... : :.:: CCDS11 IRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 110 120 130 140 150 >>CCDS32682.1 NME2 gene_id:654364|Hs108|chr17 (267 aa) initn: 711 init1: 711 opt: 711 Z-score: 969.3 bits: 186.4 E(32554): 1.1e-47 Smith-Waterman score: 711; 65.5% identity (91.2% similar) in 148 aa overlap (22-169:120-267) 10 20 30 40 50 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFK ::::.:.::::::: :::::..:::.:::. CCDS32 MLGETNPADSKPGTIRGDFCIQVGRTMANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFR 90 100 110 120 130 140 60 70 80 90 100 110 pF1KB6 LVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGAT :::.:...:::: :..:: .:..:::. ::::: :::::::::.::.::.:.:...: : CCDS32 LVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGET 150 160 170 180 190 200 120 130 140 150 160 pF1KB6 NPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE ::::. ::::::::::.::.:.:::::::.::..::.:::. .::. ... : :.:: CCDS32 NPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 210 220 230 240 250 260 >-- initn: 587 init1: 572 opt: 572 Z-score: 780.3 bits: 151.4 E(32554): 3.9e-37 Smith-Waterman score: 572; 69.6% identity (95.5% similar) in 112 aa overlap (22-133:5-116) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.::.::..:: CCDS32 MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQA 10 20 30 40 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT ::.::.:::..:..:::.. ::::: :::::::::.::.::.:.:...: :::::. ::: CCDS32 SEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGT 50 60 70 80 90 100 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::.::... CCDS32 IRGDFCIQVGRTMANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHL 110 120 130 140 150 160 >>CCDS10408.1 NME4 gene_id:4833|Hs108|chr16 (187 aa) initn: 683 init1: 652 opt: 652 Z-score: 891.4 bits: 171.5 E(32554): 2.5e-43 Smith-Waterman score: 652; 61.8% identity (88.9% similar) in 144 aa overlap (22-165:38-181) 10 20 30 40 50 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFK :::..:::::::::::::....::::.:: CCDS10 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGAT ::..:..:: : .: ::: .::..::: :..::.:::::::::.: .:::.:::.:: : CCDS10 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 NPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE . :.: :::::::: .....:.::.:::::.:.::: :::...::. : :.. : CCDS10 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA 130 140 150 160 170 180 >>CCDS66886.1 NME4 gene_id:4833|Hs108|chr16 (117 aa) initn: 489 init1: 466 opt: 479 Z-score: 659.2 bits: 127.8 E(32554): 2.1e-30 Smith-Waterman score: 479; 58.6% identity (86.5% similar) in 111 aa overlap (55-165:1-111) 30 40 50 60 70 80 pF1KB6 FLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELRERPFYGRLVKY .:..:: : .: ::: .::..::: :..: CCDS66 MKMLQAPESVLAEHYQDLRRKPFYPALIRY 10 20 30 90 100 110 120 130 140 pF1KB6 MASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGTIRGDFCIEVGKNLIHGSDSVESAR :.:::::::::.: .:::.:::.:: :. :.: :::::::: .....:.::.:::::.:. CCDS66 MSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQ 40 50 60 70 80 90 150 160 pF1KB6 REIALWFRADELLCWEDSAGHWLYE ::: :::...::. : :.. : CCDS66 REIQLWFQSSELVSWADGGQHSSIHPA 100 110 >>CCDS74107.1 NME2 gene_id:4831|Hs108|chr17 (82 aa) initn: 352 init1: 352 opt: 356 Z-score: 494.2 bits: 96.8 E(32554): 3.3e-21 Smith-Waterman score: 356; 66.7% identity (87.2% similar) in 78 aa overlap (22-96:5-82) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.:::.:...: CCDS74 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRA 10 20 30 40 70 80 90 100 110 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAM---VWQGLDVVRTSRALIGATNPADAP ::: :..:: .:..:::. ::::: ::::::: :: CCDS74 SEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMEHHSWQ 50 60 70 80 120 130 140 150 160 pF1KB6 PGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE >>CCDS73797.1 NME4 gene_id:4833|Hs108|chr16 (153 aa) initn: 492 init1: 311 opt: 312 Z-score: 430.3 bits: 85.9 E(32554): 1.2e-17 Smith-Waterman score: 426; 47.2% identity (69.4% similar) in 144 aa overlap (22-165:38-147) 10 20 30 40 50 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFK :::..:::::::::::::....::::.:: CCDS73 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGAT ::..:..: ::.: .:::.:::.:: : CCDS73 LVGMKMLQ----------------------------------VWEGYNVVRASRAMIGHT 70 80 90 120 130 140 150 160 pF1KB6 NPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE . :.: :::::::: .....:.::.:::::.:.::: :::...::. : :.. : CCDS73 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA 100 110 120 130 140 150 >>CCDS77734.1 NME6 gene_id:10201|Hs108|chr3 (186 aa) initn: 210 init1: 116 opt: 251 Z-score: 346.0 bits: 70.5 E(32554): 6e-13 Smith-Waterman score: 251; 37.5% identity (61.8% similar) in 136 aa overlap (20-151:10-145) 10 20 30 40 50 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIV-RRFERKGFKLVALKLVQ : . :. .:::.: . :. : : ... . : .: .. . CCDS77 MASILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELL 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 ASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADA--- .: .. : : . : :: :::..:::::. :.. :... :.:.: : : CCDS77 WRKEDCQRFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHV 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 PPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE : .:::.: . .: :::::: :: :::: .: CCDS77 APDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSP 120 130 140 150 160 170 CCDS77 EGGVHYVAGTGGLGPA 180 169 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:09:51 2016 done: Sat Nov 5 14:09:52 2016 Total Scan time: 1.930 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]