FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6833, 169 aa 1>>>pF1KB6833 169 - 169 aa - 169 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8352+/-0.000308; mu= 14.5446+/- 0.019 mean_var=55.7802+/-11.272, 0's: 0 Z-trim(116.3): 39 B-trim: 1410 in 1/52 Lambda= 0.171725 statistics sampled from 27274 (27313) to 27274 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.32), width: 16 Scan time: 5.430 The best scores are: opt bits E(85289) NP_002504 (OMIM: 601817) nucleoside diphosphate ki ( 169) 1138 289.5 1.8e-78 XP_005255389 (OMIM: 601817) PREDICTED: nucleoside ( 165) 847 217.4 8.8e-57 NP_000260 (OMIM: 156490,256700) nucleoside diphosp ( 152) 726 187.4 8.7e-48 NP_937818 (OMIM: 156490,256700) nucleoside diphosp ( 177) 726 187.4 9.8e-48 NP_001018148 (OMIM: 156491) nucleoside diphosphate ( 152) 711 183.7 1.1e-46 NP_002503 (OMIM: 156491) nucleoside diphosphate ki ( 152) 711 183.7 1.1e-46 NP_001018147 (OMIM: 156491) nucleoside diphosphate ( 152) 711 183.7 1.1e-46 NP_001018149 (OMIM: 156491) nucleoside diphosphate ( 152) 711 183.7 1.1e-46 NP_005000 (OMIM: 601818) nucleoside diphosphate ki ( 187) 652 169.1 3.4e-42 XP_011520805 (OMIM: 601817) PREDICTED: nucleoside ( 170) 624 162.1 3.8e-40 NP_001273364 (OMIM: 601818) nucleoside diphosphate ( 173) 504 132.4 3.5e-31 NP_001273368 (OMIM: 601818) nucleoside diphosphate ( 117) 479 126.1 1.8e-29 NP_001273367 (OMIM: 601818) nucleoside diphosphate ( 117) 479 126.1 1.8e-29 NP_001273369 (OMIM: 601818) nucleoside diphosphate ( 117) 479 126.1 1.8e-29 NP_001273365 (OMIM: 601818) nucleoside diphosphate ( 117) 479 126.1 1.8e-29 XP_011520806 (OMIM: 601817) PREDICTED: nucleoside ( 136) 383 102.4 3e-22 NP_001185611 (OMIM: 156491) nucleoside diphosphate ( 82) 356 95.5 2e-20 NP_001273362 (OMIM: 601818) nucleoside diphosphate ( 153) 312 84.8 6.5e-17 NP_001295356 (OMIM: 608294) nucleoside diphosphate ( 186) 251 69.7 2.7e-12 NP_001295357 (OMIM: 608294) nucleoside diphosphate ( 186) 251 69.7 2.7e-12 NP_001295355 (OMIM: 608294) nucleoside diphosphate ( 186) 251 69.7 2.7e-12 XP_016861003 (OMIM: 608294) PREDICTED: nucleoside ( 186) 251 69.7 2.7e-12 XP_016861002 (OMIM: 608294) PREDICTED: nucleoside ( 190) 251 69.7 2.8e-12 NP_005784 (OMIM: 608294) nucleoside diphosphate ki ( 194) 251 69.7 2.8e-12 NP_932076 (OMIM: 613465) nucleoside diphosphate ki ( 340) 250 69.6 5.3e-12 XP_016856588 (OMIM: 613465) PREDICTED: nucleoside ( 367) 250 69.7 5.7e-12 NP_037462 (OMIM: 613465) nucleoside diphosphate ki ( 376) 250 69.7 5.8e-12 NP_001295363 (OMIM: 608294) nucleoside diphosphate ( 141) 213 60.3 1.5e-09 XP_005272156 (OMIM: 603575) PREDICTED: nucleoside ( 148) 199 56.8 1.7e-08 XP_006714779 (OMIM: 603575) PREDICTED: nucleoside ( 149) 199 56.8 1.7e-08 NP_003542 (OMIM: 603575) nucleoside diphosphate ki ( 212) 195 55.9 4.6e-08 XP_016865434 (OMIM: 603575) PREDICTED: nucleoside ( 278) 195 56.0 5.7e-08 XP_016861007 (OMIM: 608294) PREDICTED: nucleoside ( 111) 166 48.6 3.9e-06 XP_016861001 (OMIM: 608294) PREDICTED: nucleoside ( 264) 162 47.8 1.6e-05 XP_016856589 (OMIM: 613465) PREDICTED: nucleoside ( 252) 159 47.0 2.5e-05 XP_005245163 (OMIM: 613465) PREDICTED: nucleoside ( 252) 159 47.0 2.5e-05 XP_016861006 (OMIM: 608294) PREDICTED: nucleoside ( 114) 149 44.3 7.3e-05 >>NP_002504 (OMIM: 601817) nucleoside diphosphate kinase (169 aa) initn: 1138 init1: 1138 opt: 1138 Z-score: 1529.9 bits: 289.5 E(85289): 1.8e-78 Smith-Waterman score: 1138; 100.0% identity (100.0% similar) in 169 aa overlap (1-169:1-169) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT 70 80 90 100 110 120 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE ::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE 130 140 150 160 >>XP_005255389 (OMIM: 601817) PREDICTED: nucleoside diph (165 aa) initn: 847 init1: 847 opt: 847 Z-score: 1140.4 bits: 217.4 E(85289): 8.8e-57 Smith-Waterman score: 847; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT 70 80 90 100 110 120 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::: XP_005 IRGDFCIEEPDSRQRLGGECPPRDRSLVPRRRAPLLGGQRWALAV 130 140 150 160 >>NP_000260 (OMIM: 156490,256700) nucleoside diphosphate (152 aa) initn: 726 init1: 726 opt: 726 Z-score: 978.9 bits: 187.4 E(85289): 8.7e-48 Smith-Waterman score: 726; 67.6% identity (93.2% similar) in 148 aa overlap (22-169:5-152) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.::.::..:: NP_000 MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQA 10 20 30 40 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT ::.::.:::..:..:::.. ::::: :::::::::.::.::.:.:...: :::::. ::: NP_000 SEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGT 50 60 70 80 90 100 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::.::.:.::::::::::..::.:::. .::. . . : .:.:: NP_000 IRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 110 120 130 140 150 >>NP_937818 (OMIM: 156490,256700) nucleoside diphosphate (177 aa) initn: 726 init1: 726 opt: 726 Z-score: 978.0 bits: 187.4 E(85289): 9.8e-48 Smith-Waterman score: 726; 67.6% identity (93.2% similar) in 148 aa overlap (22-169:30-177) 10 20 30 40 50 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKL ::::.:.::::::: :::::..:::.:::.: NP_937 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 VALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATN :.::..::::.::.:::..:..:::.. ::::: :::::::::.::.::.:.:...: :: NP_937 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 PADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::. ::::::::::.::.:.::::::::::..::.:::. .::. . . : .:.:: NP_937 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 130 140 150 160 170 >>NP_001018148 (OMIM: 156491) nucleoside diphosphate kin (152 aa) initn: 711 init1: 711 opt: 711 Z-score: 958.9 bits: 183.7 E(85289): 1.1e-46 Smith-Waterman score: 711; 65.5% identity (91.2% similar) in 148 aa overlap (22-169:5-152) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.:::.:...: NP_001 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRA 10 20 30 40 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT ::: :..:: .:..:::. ::::: :::::::::.::.::.:.:...: :::::. ::: NP_001 SEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGT 50 60 70 80 90 100 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::.::.:.:::::::.::..::.:::. .::. ... : :.:: NP_001 IRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 110 120 130 140 150 >>NP_002503 (OMIM: 156491) nucleoside diphosphate kinase (152 aa) initn: 711 init1: 711 opt: 711 Z-score: 958.9 bits: 183.7 E(85289): 1.1e-46 Smith-Waterman score: 711; 65.5% identity (91.2% similar) in 148 aa overlap (22-169:5-152) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.:::.:...: NP_002 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRA 10 20 30 40 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT ::: :..:: .:..:::. ::::: :::::::::.::.::.:.:...: :::::. ::: NP_002 SEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGT 50 60 70 80 90 100 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::.::.:.:::::::.::..::.:::. .::. ... : :.:: NP_002 IRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 110 120 130 140 150 >>NP_001018147 (OMIM: 156491) nucleoside diphosphate kin (152 aa) initn: 711 init1: 711 opt: 711 Z-score: 958.9 bits: 183.7 E(85289): 1.1e-46 Smith-Waterman score: 711; 65.5% identity (91.2% similar) in 148 aa overlap (22-169:5-152) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.:::.:...: NP_001 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRA 10 20 30 40 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT ::: :..:: .:..:::. ::::: :::::::::.::.::.:.:...: :::::. ::: NP_001 SEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGT 50 60 70 80 90 100 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::.::.:.:::::::.::..::.:::. .::. ... : :.:: NP_001 IRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 110 120 130 140 150 >>NP_001018149 (OMIM: 156491) nucleoside diphosphate kin (152 aa) initn: 711 init1: 711 opt: 711 Z-score: 958.9 bits: 183.7 E(85289): 1.1e-46 Smith-Waterman score: 711; 65.5% identity (91.2% similar) in 148 aa overlap (22-169:5-152) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA ::::.:.::::::: :::::..:::.:::.:::.:...: NP_001 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRA 10 20 30 40 70 80 90 100 110 120 pF1KB6 SEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADAPPGT ::: :..:: .:..:::. ::::: :::::::::.::.::.:.:...: :::::. ::: NP_001 SEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGT 50 60 70 80 90 100 130 140 150 160 pF1KB6 IRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE :::::::.::.:.:::::::.::..::.:::. .::. ... : :.:: NP_001 IRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 110 120 130 140 150 >>NP_005000 (OMIM: 601818) nucleoside diphosphate kinase (187 aa) initn: 683 init1: 652 opt: 652 Z-score: 878.5 bits: 169.1 E(85289): 3.4e-42 Smith-Waterman score: 652; 61.8% identity (88.9% similar) in 144 aa overlap (22-165:38-181) 10 20 30 40 50 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFK :::..:::::::::::::....::::.:: NP_005 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGAT ::..:..:: : .: ::: .::..::: :..::.:::::::::.: .:::.:::.:: : NP_005 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 NPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE . :.: :::::::: .....:.::.:::::.:.::: :::...::. : :.. : NP_005 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA 130 140 150 160 170 180 >>XP_011520805 (OMIM: 601817) PREDICTED: nucleoside diph (170 aa) initn: 668 init1: 383 opt: 624 Z-score: 841.7 bits: 162.1 E(85289): 3.8e-40 Smith-Waterman score: 624; 62.6% identity (71.8% similar) in 174 aa overlap (1-169:1-170) 10 20 30 40 50 60 pF1KB6 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQV 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 SEELLREHYAELRERPFYGRLVKYMAS--GPVVAMVWQGLD---VVRTSRALIGATNPAD . . : . .: . ..: : : : . .:. : :. XP_011 GARPPRSCCVSTTPSCVNARSTAALSSIWPPGRWWPWYGRGWTWCAPRGRSSEPRTRPTP 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 APPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE : . : : ...:::::::::::::::::::::::::::::::::::::: XP_011 RPAPSA-G---ISASRNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE 130 140 150 160 170 169 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:09:52 2016 done: Sat Nov 5 14:09:53 2016 Total Scan time: 5.430 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]