FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6836, 175 aa 1>>>pF1KB6836 175 - 175 aa - 175 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7874+/-0.000329; mu= 16.0504+/- 0.021 mean_var=70.8840+/-14.096, 0's: 0 Z-trim(115.2): 30 B-trim: 0 in 0/55 Lambda= 0.152335 statistics sampled from 25528 (25546) to 25528 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.3), width: 16 Scan time: 5.790 The best scores are: opt bits E(85289) NP_000137 (OMIM: 134790,600886,606159,615604) ferr ( 175) 1152 261.7 4.4e-70 NP_002023 (OMIM: 134770,615517) ferritin heavy cha ( 183) 696 161.5 6.6e-40 NP_803431 (OMIM: 608847) ferritin, mitochondrial p ( 242) 654 152.4 4.9e-37 NP_114100 (OMIM: 300308) ferritin heavy polypeptid ( 183) 576 135.1 5.8e-32 >>NP_000137 (OMIM: 134790,600886,606159,615604) ferritin (175 aa) initn: 1152 init1: 1152 opt: 1152 Z-score: 1379.3 bits: 261.7 E(85289): 4.4e-70 Smith-Waterman score: 1152; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175) 10 20 30 40 50 60 pF1KB6 MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSA 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 RTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD 130 140 150 160 170 >>NP_002023 (OMIM: 134770,615517) ferritin heavy chain [ (183 aa) initn: 696 init1: 696 opt: 696 Z-score: 837.4 bits: 161.5 E(85289): 6.6e-40 Smith-Waterman score: 696; 56.7% identity (86.0% similar) in 171 aa overlap (2-172:6-176) 10 20 30 40 50 pF1KB6 MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELA .::.:::: : :::.: .:: : :::.:::...:::::::::.. ...: . . NP_002 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 EEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHA .:.:: :.:.:.::::::: ..:::::: :.: . .::. :. :::..::.::.:: NP_002 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD :.. ..:::::::.:::.:.:.:: ::..:::.:::...:.::.::.::::.. :: NP_002 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD 130 140 150 160 170 180 NP_002 NES >>NP_803431 (OMIM: 608847) ferritin, mitochondrial precu (242 aa) initn: 660 init1: 644 opt: 654 Z-score: 785.9 bits: 152.4 E(85289): 4.9e-37 Smith-Waterman score: 654; 54.3% identity (82.7% similar) in 173 aa overlap (3-175:66-238) 10 20 30 pF1KB6 MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYL :..:::. : :::.: .:: : :::.:: NP_803 RPLDPRQIAPRRPLAAAASSRDPTGPAAGPSRVRQNFHPDSEAAINRQINLELYASYVYL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 SLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGK :...::.::::::.. :..: . ..:. : :.:...::::::: .:::::: .:.: . NP_803 SMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWES 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB6 TPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNL ::. :. :::..::.::.::::.: . ::::::::::..:.:.:: ::..:::. :: NP_803 GLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNL 160 170 180 190 200 210 160 170 pF1KB6 HRLGGPEAGLGEYLFERLTLKHD ..:.:.:::.::::. :: .. NP_803 VKMGAPDAGLAEYLFDTHTLGNENKQN 220 230 240 >>NP_114100 (OMIM: 300308) ferritin heavy polypeptide-li (183 aa) initn: 576 init1: 576 opt: 576 Z-score: 694.9 bits: 135.1 E(85289): 5.8e-32 Smith-Waterman score: 576; 49.4% identity (81.8% similar) in 170 aa overlap (3-172:7-176) 10 20 30 40 50 pF1KB6 MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELA ::.::.:.:. .::.:: ..: : .:: :::..:::.:::::::. ..: .:. NP_114 MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 EEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHA ..: : ..:...:: :::. ..::.:: . : . ::..:. :::..::.::::. NP_114 DDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD :. . ::.:: :::.:.: :.:: ::..: ...::... .:::::.::::..::: NP_114 LAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRV 130 140 150 160 170 180 NP_114 KET 175 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:56:28 2016 done: Sat Nov 5 11:56:29 2016 Total Scan time: 5.790 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]