FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6837, 172 aa 1>>>pF1KB6837 172 - 172 aa - 172 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5014+/-0.000288; mu= 4.5816+/- 0.018 mean_var=171.2402+/-34.233, 0's: 0 Z-trim(123.3): 3 B-trim: 22 in 1/57 Lambda= 0.098010 statistics sampled from 42748 (42751) to 42748 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.819), E-opt: 0.2 (0.501), width: 16 Scan time: 6.730 The best scores are: opt bits E(85289) NP_036520 (OMIM: 604310,614171) biogenesis of lyso ( 172) 1112 167.8 7.7e-42 NP_001298184 (OMIM: 604310,614171) biogenesis of l ( 177) 913 139.7 2.3e-33 NP_001298185 (OMIM: 604310,614171) biogenesis of l ( 91) 300 52.8 1.8e-07 >>NP_036520 (OMIM: 604310,614171) biogenesis of lysosome (172 aa) initn: 1112 init1: 1112 opt: 1112 Z-score: 872.1 bits: 167.8 E(85289): 7.7e-42 Smith-Waterman score: 1112; 100.0% identity (100.0% similar) in 172 aa overlap (1-172:1-172) 10 20 30 40 50 60 pF1KB6 MSVPGPSSPDGALTRPPYCLEAGEPTPGLSDTSPDEGLIEDLTIEDKAVEQLAEGLLSHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MSVPGPSSPDGALTRPPYCLEAGEPTPGLSDTSPDEGLIEDLTIEDKAVEQLAEGLLSHY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LPDLQRSKQALQELTQNQVVLLDTLEQEISKFKECHSMLDINALFAEAKHYHAKLVNIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LPDLQRSKQALQELTQNQVVLLDTLEQEISKFKECHSMLDINALFAEAKHYHAKLVNIRK 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EMLMLHEKTSKLKKRALKLQQKRQKEELEREQQREKEFEREKQLTARPAKRM :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EMLMLHEKTSKLKKRALKLQQKRQKEELEREQQREKEFEREKQLTARPAKRM 130 140 150 160 170 >>NP_001298184 (OMIM: 604310,614171) biogenesis of lysos (177 aa) initn: 913 init1: 913 opt: 913 Z-score: 719.9 bits: 139.7 E(85289): 2.3e-33 Smith-Waterman score: 913; 100.0% identity (100.0% similar) in 145 aa overlap (28-172:33-177) 10 20 30 40 50 pF1KB6 MSVPGPSSPDGALTRPPYCLEAGEPTPGLSDTSPDEGLIEDLTIEDKAVEQLAEGLL :::::::::::::::::::::::::::::: NP_001 GTEVPRGSFVLGVQLKAVDGEAILSLCVDSGLSDTSPDEGLIEDLTIEDKAVEQLAEGLL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SHYLPDLQRSKQALQELTQNQVVLLDTLEQEISKFKECHSMLDINALFAEAKHYHAKLVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHYLPDLQRSKQALQELTQNQVVLLDTLEQEISKFKECHSMLDINALFAEAKHYHAKLVN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 IRKEMLMLHEKTSKLKKRALKLQQKRQKEELEREQQREKEFEREKQLTARPAKRM ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRKEMLMLHEKTSKLKKRALKLQQKRQKEELEREQQREKEFEREKQLTARPAKRM 130 140 150 160 170 >>NP_001298185 (OMIM: 604310,614171) biogenesis of lysos (91 aa) initn: 300 init1: 300 opt: 300 Z-score: 255.3 bits: 52.8 E(85289): 1.8e-07 Smith-Waterman score: 300; 100.0% identity (100.0% similar) in 48 aa overlap (28-75:33-80) 10 20 30 40 50 pF1KB6 MSVPGPSSPDGALTRPPYCLEAGEPTPGLSDTSPDEGLIEDLTIEDKAVEQLAEGLL :::::::::::::::::::::::::::::: NP_001 GTEVPRGSFVLGVQLKAVDGEAILSLCVDSGLSDTSPDEGLIEDLTIEDKAVEQLAEGLL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SHYLPDLQRSKQALQELTQNQVVLLDTLEQEISKFKECHSMLDINALFAEAKHYHAKLVN :::::::::::::::::: NP_001 SHYLPDLQRSKQALQELTLLRLNTIMPSW 70 80 90 172 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:03:39 2016 done: Sat Nov 5 14:03:40 2016 Total Scan time: 6.730 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]