FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6840, 191 aa 1>>>pF1KB6840 191 - 191 aa - 191 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0551+/-0.000827; mu= 13.9730+/- 0.049 mean_var=58.8586+/-11.904, 0's: 0 Z-trim(106.2): 32 B-trim: 165 in 1/48 Lambda= 0.167174 statistics sampled from 8845 (8857) to 8845 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.272), width: 16 Scan time: 1.880 The best scores are: opt bits E(32554) CCDS4373.1 KCNMB1 gene_id:3779|Hs108|chr5 ( 191) 1272 314.9 1.9e-86 CCDS3223.1 KCNMB2 gene_id:10242|Hs108|chr3 ( 235) 534 136.9 8.8e-33 CCDS43172.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 257) 235 64.8 4.9e-11 CCDS43173.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 275) 235 64.9 5.1e-11 CCDS3225.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 277) 235 64.9 5.2e-11 CCDS3226.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 279) 235 64.9 5.2e-11 >>CCDS4373.1 KCNMB1 gene_id:3779|Hs108|chr5 (191 aa) initn: 1272 init1: 1272 opt: 1272 Z-score: 1665.3 bits: 314.9 E(32554): 1.9e-86 Smith-Waterman score: 1272; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS 130 140 150 160 170 180 190 pF1KB6 NQYLSILAAQK ::::::::::: CCDS43 NQYLSILAAQK 190 >>CCDS3223.1 KCNMB2 gene_id:10242|Hs108|chr3 (235 aa) initn: 532 init1: 339 opt: 534 Z-score: 702.0 bits: 136.9 E(32554): 8.8e-33 Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226) 10 20 30 pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYY .: : : : :: ::. ::..:.::... :. CCDS32 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF 10 20 30 40 50 60 40 50 60 70 80 pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA .: :.: :..::::.::.: :....: . . . : :. ::::: .::.... CCDS32 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET :. .:::::.: ::.::::: :.. . . :. : .:.. : : :.: :.::. CCDS32 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK 130 140 150 160 170 180 150 160 170 180 190 pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK ::.. .::. ..:. :::::: ...::. :.:::: .::::.: CCDS32 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR 190 200 210 220 230 >>CCDS43172.1 KCNMB3 gene_id:27094|Hs108|chr3 (257 aa) initn: 324 init1: 153 opt: 235 Z-score: 311.7 bits: 64.8 E(32554): 4.9e-11 Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:32-218) 10 20 30 40 pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL :: ::. :: .:. .:. ...: ::.: CCDS43 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 10 20 30 40 50 60 50 60 70 80 90 pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH .. :. .:: : :.:.: :. .. . .:::: .::.: :. :.:.. CCDS43 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR .:.. . : .: : : .. . .. .. :.... : :: .: .. .:.. . CCDS43 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 130 140 150 160 170 180 160 170 180 190 pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK : .:.. ::::.. : :: ::..::. .:.::.: CCDS43 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 190 200 210 220 230 240 CCDS43 FKLCIMRRSKGRAEKS 250 >>CCDS43173.1 KCNMB3 gene_id:27094|Hs108|chr3 (275 aa) initn: 324 init1: 153 opt: 235 Z-score: 311.2 bits: 64.9 E(32554): 5.1e-11 Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:50-236) 10 20 30 40 pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL :: ::. :: .:. .:. ...: ::.: CCDS43 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 20 30 40 50 60 70 50 60 70 80 90 pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH .. :. .:: : :.:.: :. .. . .:::: .::.: :. :.:.. CCDS43 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR .:.. . : .: : : .. . .. .. :.... : :: .: .. .:.. . CCDS43 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 140 150 160 170 180 190 160 170 180 190 pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK : .:.. ::::.. : :: ::..::. .:.::.: CCDS43 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 200 210 220 230 240 250 CCDS43 FKLCIMRRSKGRAEKS 260 270 >>CCDS3225.1 KCNMB3 gene_id:27094|Hs108|chr3 (277 aa) initn: 324 init1: 153 opt: 235 Z-score: 311.2 bits: 64.9 E(32554): 5.2e-11 Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:52-238) 10 20 30 40 pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL :: ::. :: .:. .:. ...: ::.: CCDS32 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 30 40 50 60 70 80 50 60 70 80 90 pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH .. :. .:: : :.:.: :. .. . .:::: .::.: :. :.:.. CCDS32 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR .:.. . : .: : : .. . .. .. :.... : :: .: .. .:.. . CCDS32 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 150 160 170 180 190 200 160 170 180 190 pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK : .:.. ::::.. : :: ::..::. .:.::.: CCDS32 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 210 220 230 240 250 260 CCDS32 FKLCIMRRSKGRAEKS 270 >>CCDS3226.1 KCNMB3 gene_id:27094|Hs108|chr3 (279 aa) initn: 324 init1: 153 opt: 235 Z-score: 311.1 bits: 64.9 E(32554): 5.2e-11 Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:54-240) 10 20 30 40 pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL :: ::. :: .:. .:. ...: ::.: CCDS32 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 30 40 50 60 70 80 50 60 70 80 90 pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH .. :. .:: : :.:.: :. .. . .:::: .::.: :. :.:.. CCDS32 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR .:.. . : .: : : .. . .. .. :.... : :: .: .. .:.. . CCDS32 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 150 160 170 180 190 200 160 170 180 190 pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK : .:.. ::::.. : :: ::..::. .:.::.: CCDS32 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 210 220 230 240 250 260 CCDS32 FKLCIMRRSKGRAEKS 270 191 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:56:36 2016 done: Fri Nov 4 14:56:36 2016 Total Scan time: 1.880 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]